HK1132742A1 - Substituted oxindole derivative and its use as a vasopressin receptor modulator - Google Patents

Substituted oxindole derivative and its use as a vasopressin receptor modulator

Info

Publication number
HK1132742A1
HK1132742A1 HK10100157.7A HK10100157A HK1132742A1 HK 1132742 A1 HK1132742 A1 HK 1132742A1 HK 10100157 A HK10100157 A HK 10100157A HK 1132742 A1 HK1132742 A1 HK 1132742A1
Authority
HK
Hong Kong
Prior art keywords
receptor modulator
vasopressin receptor
oxindole derivative
substituted oxindole
substituted
Prior art date
Application number
HK10100157.7A
Other languages
English (en)
Inventor
Astrid Netz
Thorsten Oost
Herve Geneste
Wilfried Martin Braje
Wolfgang Wernet
Liliane Unger
Wilfried Horneberger
Wilfried Lubisch
Original Assignee
Abbott Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Gmbh & Co Kg filed Critical Abbott Gmbh & Co Kg
Publication of HK1132742A1 publication Critical patent/HK1132742A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
HK10100157.7A 2006-12-30 2010-01-08 Substituted oxindole derivative and its use as a vasopressin receptor modulator HK1132742A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102006062506 2006-12-30
PCT/EP2007/064621 WO2008080972A1 (en) 2006-12-30 2007-12-28 Substituted oxindole derivative and its use as a vasopressin receptor modulator

Publications (1)

Publication Number Publication Date
HK1132742A1 true HK1132742A1 (en) 2010-03-05

Family

ID=39122411

Family Applications (1)

Application Number Title Priority Date Filing Date
HK10100157.7A HK1132742A1 (en) 2006-12-30 2010-01-08 Substituted oxindole derivative and its use as a vasopressin receptor modulator

Country Status (4)

Country Link
EP (1) EP2114922B1 (es)
ES (1) ES2422275T3 (es)
HK (1) HK1132742A1 (es)
WO (1) WO2008080972A1 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8580842B2 (en) 2003-09-30 2013-11-12 Abbott Gmbh & Co. Kg Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them
US8486979B2 (en) 2006-12-12 2013-07-16 Abbvie Inc. 1,2,4 oxadiazole compounds and methods of use thereof
US20080167286A1 (en) 2006-12-12 2008-07-10 Abbott Laboratories Pharmaceutical compositions and their methods of use
UY30846A1 (es) 2006-12-30 2008-07-31 Abbott Gmbh & Amp Derivados de oxindol sustituidos, medicamentos que los comprenden y uso de los mismos
WO2009071691A2 (de) * 2007-12-07 2009-06-11 Abbott Gmbh & Co. Kg Oxindol-derivate und ihre verwendung als medikament
WO2010009775A1 (de) * 2007-12-07 2010-01-28 Abbott Gmbh & Co. Kg Carbamat-substituierte oxindol-derivate und ihre verwendung zur behandlung von vasopressin-abhängigen erkrankungen
JP5701607B2 (ja) 2007-12-07 2015-04-15 アッヴィ・ドイチュラント・ゲー・エム・ベー・ハー・ウント・コー・カー・ゲー アミドメチル置換オキシインドール誘導体およびバソプレッシン依存性疾患の治療へのこれらの使用
NZ586651A (en) * 2007-12-07 2012-06-29 Abbott Gmbh & Co Kg 5-halogen-substituted oxindole derivatives and use thereof for treating vasopressine-dependent diseases
MX2010006204A (es) 2007-12-07 2011-03-16 Abbott Gmbh & Co Kg Derivados de oxindol 5,6-disubstituidos y el uso de los mismos para el tratamiento de enfermedades dependientes de la vasopresina.
EP2435080A2 (en) 2009-05-29 2012-04-04 Abbott Laboratories Pharmaceutical compositions for the treatment of pain
WO2010142739A1 (en) * 2009-06-10 2010-12-16 Abbott Gmbh & Co. Kg Use of substituted oxindole derivatives for the treatment and prophylaxis of pain
MX2015012393A (es) 2013-03-14 2016-04-28 Abbvie Deutschland Derivados oxindol con un sustituyente oxetano y uso de los mismos para tratar enfermedades relacionadas con la vasopresina.
AR095327A1 (es) 2013-03-14 2015-10-07 Abbvie Deutschland Derivados oxindol con un sustituyente oxetano y uso de los mismos para tratar enfermedades relacionadas con la vasopresina
WO2015091934A1 (en) 2013-12-20 2015-06-25 AbbVie Deutschland GmbH & Co. KG Oxindole derivatives carrying an amine-substituted piperidyl-azetidinyl substituent and use thereof for treating vasopressine-related diseases
WO2015091931A1 (en) 2013-12-20 2015-06-25 AbbVie Deutschland GmbH & Co. KG Oxindole derivatives carrying a piperidyl-substituted azetidinyl substituent and use thereof for treating vasopressine-related diseases
US9527856B2 (en) 2014-05-15 2016-12-27 AbbVie Deutschland GmbH & Co. KG Oxindole compounds carrying a CO-bound spiro substituent and use thereof for treating vasopressin-related diseases

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050070718A1 (en) * 2003-09-30 2005-03-31 Abbott Gmbh & Co. Kg Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them
DE102004033834A1 (de) * 2004-07-13 2006-02-02 Abbott Gmbh & Co. Kg Substituierte Oxindol-Derivate und diese enthaltende Arzneimittel
DE102005014904A1 (de) * 2005-03-26 2007-02-01 Abbott Gmbh & Co. Kg Substituierte Oxindol-Derivate, diese enthaltende Arzneimittel und deren Verwendung
EP1861392A2 (de) * 2005-03-24 2007-12-05 Abbott GmbH & Co. KG Substituierte oxindol-derivate, diese enthaltende arzneimittel und deren verwendung

Also Published As

Publication number Publication date
ES2422275T3 (es) 2013-09-10
EP2114922B1 (en) 2013-04-24
WO2008080972A1 (en) 2008-07-10
EP2114922A1 (en) 2009-11-11

Similar Documents

Publication Publication Date Title
HK1132742A1 (en) Substituted oxindole derivative and its use as a vasopressin receptor modulator
MX2009007104A (es) Derivados de oxindol sustituido y su uso como ligandos del receptor de vasopresina.
GEP20135907B (en) L-(piperidin-4-yl)-pyrazole derivatives as gpr 119 modulators
GEP20146125B (en) Aminopyrimidines as syk inhibitors
MX2009003316A (es) Derivados de pirazina-2-carboxamida como moduladores receptores de cb2.
TNSN08373A1 (en) Azolopyrimidines as inhibitors of cannabinoid 1 activity
TNSN08283A1 (en) Cytotoxic agents comprising new tomaymycin derivatives and their therapeutic use
PL1979355T3 (pl) Pochodne spiro imidazoli jako modulatory PPAR
MX2009006540A (es) Derivados de ester y amida de indazolilo para el tratamiento de enfermedades mediadas por un receptor de glucocorticoides.
MX2010009752A (es) Compuestos de oxadiazoantraceno para el tratamiento de diabetes.
UA94749C2 (en) Benzimidazole modulators of vr1
GEP20135744B (en) Quinuclidine carbonate derivatives and medicinal compositions containing the same
GEP20135793B (en) Heteroaryls amide derivatives and their use as glucokinase activators
MX2007002393A (es) Compuestos indolicos sustituidos y su uso como moduladores del receptor de 5-hidroxitriptamina 6 (5-ht6).
IL189191A0 (en) Thiazolyl piperidine derivatives useful as h3 receptor modulators
MX2008013196A (es) 5-amido-2-carboxiamida-indoles.
TW200626158A (en) Naphthaline derivatives
MEP1008A (xx) 3-aminociklopentankarboksamidi kao modulatori receptora hemokina
MX2010006204A (es) Derivados de oxindol 5,6-disubstituidos y el uso de los mismos para el tratamiento de enfermedades dependientes de la vasopresina.
NO20085029L (no) Substituerte pyridylamidforbindelser som modulatorer av histamin H3 reseptoren
MX2010006206A (es) Derivados de oxindol substituidos por 5-halogeno y el uso de los mismos para el tratamiento de enfermedades dependientes de la vasopresina.
MX2007011698A (es) Derivados de oxindol sustituido, medicamentos que contienen dichos derivados y uso de los mismos.
GEP20135806B (en) Lactams as beta secretase inhibitors
MX2009003981A (es) Agentes moduladores del receptor de calcio.
NO20083058L (no) Cykloheksylsulfonamidderivater med H3 reseptor aktivitet

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20171228