ES2422275T3 - Derivado del oxindol sustituido y su uso como un modulador del receptor de la vasopresina - Google Patents
Derivado del oxindol sustituido y su uso como un modulador del receptor de la vasopresinaInfo
- Publication number
- ES2422275T3 ES2422275T3 ES07866323T ES07866323T ES2422275T3 ES 2422275 T3 ES2422275 T3 ES 2422275T3 ES 07866323 T ES07866323 T ES 07866323T ES 07866323 T ES07866323 T ES 07866323T ES 2422275 T3 ES2422275 T3 ES 2422275T3
- Authority
- ES
- Spain
- Prior art keywords
- derived
- receptor modulator
- vasopressin receptor
- substituted oxindole
- oxindole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
Abstract
Compuesto de la fórmula general (I) **Fórmula** y las sales farmacéuticamente aceptables y las formas tautoméricas de este.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102006062506 | 2006-12-30 | ||
PCT/EP2007/064621 WO2008080972A1 (en) | 2006-12-30 | 2007-12-28 | Substituted oxindole derivative and its use as a vasopressin receptor modulator |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2422275T3 true ES2422275T3 (es) | 2013-09-10 |
Family
ID=39122411
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES07866323T Active ES2422275T3 (es) | 2006-12-30 | 2007-12-28 | Derivado del oxindol sustituido y su uso como un modulador del receptor de la vasopresina |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP2114922B1 (es) |
ES (1) | ES2422275T3 (es) |
HK (1) | HK1132742A1 (es) |
WO (1) | WO2008080972A1 (es) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8580842B2 (en) | 2003-09-30 | 2013-11-12 | Abbott Gmbh & Co. Kg | Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them |
US20080167286A1 (en) | 2006-12-12 | 2008-07-10 | Abbott Laboratories | Pharmaceutical compositions and their methods of use |
US8486979B2 (en) | 2006-12-12 | 2013-07-16 | Abbvie Inc. | 1,2,4 oxadiazole compounds and methods of use thereof |
UY30846A1 (es) | 2006-12-30 | 2008-07-31 | Abbott Gmbh & Amp | Derivados de oxindol sustituidos, medicamentos que los comprenden y uso de los mismos |
US8703774B2 (en) | 2007-12-07 | 2014-04-22 | AbbVie Deutschland GmbH & Co. KG | Carbamate-substituted oxindole derivatives and use thereof for the treatment of vasopressin-dependent diseases |
JP5595926B2 (ja) * | 2007-12-07 | 2014-09-24 | アボット ゲーエムベーハー ウント カンパニー カーゲー | 5−ハロゲン−置換オキシインドール誘導体およびバソプレッシン依存性疾患の治療へのこれらの使用 |
WO2009071691A2 (de) * | 2007-12-07 | 2009-06-11 | Abbott Gmbh & Co. Kg | Oxindol-derivate und ihre verwendung als medikament |
MX2010006202A (es) * | 2007-12-07 | 2011-03-04 | Abbott Gmbh & Co Kg | Derivados de oxindol substituidos por amidometil y el uso de los mismos para el tratamiento de enfermedades dependientes de la vasopresina. |
CN102026995B (zh) * | 2007-12-07 | 2014-10-29 | Abbvie德国有限责任两合公司 | 5,6-二取代的羟吲哚衍生物和其用途 |
WO2010138600A2 (en) | 2009-05-29 | 2010-12-02 | Abbott Laboratories | Pharmaceutical compositions for the treatment of pain |
CA2763931A1 (en) * | 2009-06-10 | 2010-12-16 | Abbott Gmbh & Co. Kg | Use of substituted oxindole derivatives for the treatment and prophylaxis of pain |
US9273036B2 (en) | 2013-03-14 | 2016-03-01 | AbbVie Deutschland GmbH & Co. KG | Oxindole derivatives carrying an oxetane substituent and use thereof for treating vasopressine-related diseases |
CA2903141A1 (en) | 2013-03-14 | 2014-09-18 | AbbVie Deutschland GmbH & Co. KG | Oxindole derivatives carrying an oxetane substituent and use thereof for treating vasopressine-related diseases |
US9862704B2 (en) | 2013-12-20 | 2018-01-09 | AbbVie Deutschland GmbH & Co. KG | Oxindole derivatives carrying an amine-substituted piperidyl-acetidinyl substituent and use thereof for treating vasopressine-related diseases |
WO2015091931A1 (en) | 2013-12-20 | 2015-06-25 | AbbVie Deutschland GmbH & Co. KG | Oxindole derivatives carrying a piperidyl-substituted azetidinyl substituent and use thereof for treating vasopressine-related diseases |
WO2015173392A1 (en) | 2014-05-15 | 2015-11-19 | AbbVie Deutschland GmbH & Co. KG | Oxindole compounds carrying a co-bound spiro substituent and use thereof for treating vasopressin-related diseases |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050070718A1 (en) * | 2003-09-30 | 2005-03-31 | Abbott Gmbh & Co. Kg | Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them |
DE102004033834A1 (de) * | 2004-07-13 | 2006-02-02 | Abbott Gmbh & Co. Kg | Substituierte Oxindol-Derivate und diese enthaltende Arzneimittel |
MX2007011693A (es) * | 2005-03-24 | 2008-03-11 | Abbott Gmbh & Co Kg | Derivados de oxindoles sustituidos, farmacos que contienen dichos derivados y uso de los mismos. |
DE102005014904A1 (de) * | 2005-03-26 | 2007-02-01 | Abbott Gmbh & Co. Kg | Substituierte Oxindol-Derivate, diese enthaltende Arzneimittel und deren Verwendung |
-
2007
- 2007-12-28 WO PCT/EP2007/064621 patent/WO2008080972A1/en active Application Filing
- 2007-12-28 EP EP07866323.4A patent/EP2114922B1/en active Active
- 2007-12-28 ES ES07866323T patent/ES2422275T3/es active Active
-
2010
- 2010-01-08 HK HK10100157.7A patent/HK1132742A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
HK1132742A1 (en) | 2010-03-05 |
WO2008080972A1 (en) | 2008-07-10 |
EP2114922A1 (en) | 2009-11-11 |
EP2114922B1 (en) | 2013-04-24 |
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