HK1131058A1 - Nitrogen containing substituted heterocycles as platelet adp receptor inhibitors - Google Patents
Nitrogen containing substituted heterocycles as platelet adp receptor inhibitorsInfo
- Publication number
- HK1131058A1 HK1131058A1 HK09110735.0A HK09110735A HK1131058A1 HK 1131058 A1 HK1131058 A1 HK 1131058A1 HK 09110735 A HK09110735 A HK 09110735A HK 1131058 A1 HK1131058 A1 HK 1131058A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- nitrogen containing
- receptor inhibitors
- containing substituted
- substituted heterocycles
- adp receptor
- Prior art date
Links
- 102000007466 Purinergic P2 Receptors Human genes 0.000 title 1
- 108010085249 Purinergic P2 Receptors Proteins 0.000 title 1
- 125000000623 heterocyclic group Chemical group 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/536—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
- C07D239/96—Two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
- C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D265/20—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 4
- C07D265/22—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US84632806P | 2006-09-20 | 2006-09-20 | |
US11/856,616 US7834023B2 (en) | 2006-09-20 | 2007-09-17 | Substituted dihydroquinazolines as platelet ADP receptor inhibitors |
PCT/US2007/079076 WO2008036843A2 (en) | 2006-09-20 | 2007-09-20 | Nitrogen containing substituted heterocycles as platelet adp receptor inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1131058A1 true HK1131058A1 (en) | 2010-01-15 |
Family
ID=39048759
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK09110735.0A HK1131058A1 (en) | 2006-09-20 | 2009-11-17 | Nitrogen containing substituted heterocycles as platelet adp receptor inhibitors |
Country Status (17)
Country | Link |
---|---|
US (2) | US7834023B2 (xx) |
EP (1) | EP2094272B1 (xx) |
JP (1) | JP5266232B2 (xx) |
KR (1) | KR20090057314A (xx) |
AU (1) | AU2007299723A1 (xx) |
BR (1) | BRPI0718444A2 (xx) |
CA (1) | CA2664411A1 (xx) |
CO (1) | CO6160324A2 (xx) |
HK (1) | HK1131058A1 (xx) |
IL (1) | IL197726A0 (xx) |
MA (1) | MA30775B1 (xx) |
MX (1) | MX2009003017A (xx) |
NO (1) | NO20091331L (xx) |
NZ (1) | NZ576162A (xx) |
RU (1) | RU2009114827A (xx) |
TN (1) | TN2009000091A1 (xx) |
WO (1) | WO2008036843A2 (xx) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100260825A1 (en) * | 2009-04-13 | 2010-10-14 | Nair Madhavan G | Antifolates for the treatment of cardiovascular, inflammatory, neoplastic, autoimmune and related diseases in sublingual dosage units, film strips, or skin patches |
CA2839699A1 (en) | 2011-06-24 | 2012-12-27 | Amgen Inc. | Trpm8 antagonists and their use in treatments |
MX2013015058A (es) | 2011-06-24 | 2014-01-20 | Amgen Inc | Antagonistas de melastatina 8 de potencial receptor transitorio y su uso en tratamientos. |
US8952009B2 (en) | 2012-08-06 | 2015-02-10 | Amgen Inc. | Chroman derivatives as TRPM8 inhibitors |
KR20150046259A (ko) | 2012-08-23 | 2015-04-29 | 앨리오스 바이오파마 인크. | 파라믹소바이러스 바이러스성 감염의 치료용 화합물 |
CA2988572A1 (en) | 2015-06-26 | 2016-12-29 | Takeda Pharmaceutical Company Limited | 2,3-dihydro-4h-1,3-benzoxazin-4-one derivatives as modulators of cholinergic muscarinic m1 receptor |
JP6787913B2 (ja) | 2015-10-20 | 2020-11-18 | 武田薬品工業株式会社 | 複素環化合物 |
JP7089062B2 (ja) | 2018-04-30 | 2022-06-21 | ユニティ バイオテクノロジー インコーポレイテッド | 老化細胞によって引き起こされるかまたは媒介される状態の臨床管理における使用のためおよびがんを治療するための、Bclファミリーアンタゴニストであるホスホリジン |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL135175B2 (en) * | 1983-12-22 | 1985-10-31 | Method of printing of articles made of polyamide fibres | |
DE19650975A1 (de) * | 1996-12-09 | 1998-06-10 | Basf Ag | Neue heterocyclisch substituierte Benzamide und deren Anwendung |
IL145357A0 (en) | 1999-03-17 | 2002-06-30 | Astrazeneca Ab | Amide derivatives |
US6906063B2 (en) * | 2000-02-04 | 2005-06-14 | Portola Pharmaceuticals, Inc. | Platelet ADP receptor inhibitors |
FR2837201A1 (fr) | 2002-03-18 | 2003-09-19 | Servier Lab | Nouveaux composes derives de la quinazoline, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
JP2005097276A (ja) * | 2003-08-22 | 2005-04-14 | Takeda Chem Ind Ltd | 縮合ピリミジン誘導体およびその用途 |
KR20060113700A (ko) | 2003-10-03 | 2006-11-02 | 포톨라 파마슈티컬스, 인코포레이티드 | 2,4-디옥소-3-퀴나졸리닐아릴 설포닐우레아 |
KR20060113699A (ko) * | 2003-10-03 | 2006-11-02 | 포톨라 파마슈티컬스, 인코포레이티드 | 치환된 이소퀴놀리논 |
CN101001845A (zh) | 2004-06-15 | 2007-07-18 | 阿斯利康(瑞典)有限公司 | 作为抗癌药物的取代喹唑酮 |
US20070010537A1 (en) * | 2004-08-20 | 2007-01-11 | Kazumasa Hamamura | Fused pyramidine derivative and use thereof |
US7205296B2 (en) | 2004-09-29 | 2007-04-17 | Portola Pharmaceuticals, Inc. | Substituted 2H-1,3-benzoxazin-4(3H)-ones |
WO2007149031A1 (en) | 2006-06-19 | 2007-12-27 | Astrazeneca Ab | Isoquinoline derivatives and their use as inhibitors of cytokine mediated diseases |
-
2007
- 2007-09-17 US US11/856,616 patent/US7834023B2/en not_active Expired - Fee Related
- 2007-09-20 NZ NZ576162A patent/NZ576162A/en not_active IP Right Cessation
- 2007-09-20 JP JP2009529403A patent/JP5266232B2/ja not_active Expired - Fee Related
- 2007-09-20 RU RU2009114827/15A patent/RU2009114827A/ru not_active Application Discontinuation
- 2007-09-20 BR BRPI0718444-1A2A patent/BRPI0718444A2/pt not_active IP Right Cessation
- 2007-09-20 KR KR1020097007782A patent/KR20090057314A/ko not_active Application Discontinuation
- 2007-09-20 AU AU2007299723A patent/AU2007299723A1/en not_active Abandoned
- 2007-09-20 EP EP07842909.9A patent/EP2094272B1/en active Active
- 2007-09-20 WO PCT/US2007/079076 patent/WO2008036843A2/en active Application Filing
- 2007-09-20 MX MX2009003017A patent/MX2009003017A/es active IP Right Grant
- 2007-09-20 CA CA002664411A patent/CA2664411A1/en not_active Abandoned
-
2009
- 2009-03-19 IL IL197726A patent/IL197726A0/en unknown
- 2009-03-19 TN TN2009000091A patent/TN2009000091A1/fr unknown
- 2009-03-20 CO CO09029291A patent/CO6160324A2/es unknown
- 2009-03-31 NO NO20091331A patent/NO20091331L/no not_active Application Discontinuation
- 2009-04-02 MA MA31756A patent/MA30775B1/fr unknown
- 2009-11-17 HK HK09110735.0A patent/HK1131058A1/xx not_active IP Right Cessation
-
2010
- 2010-10-26 US US12/912,367 patent/US20110098247A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP2094272B1 (en) | 2014-03-26 |
US20110098247A1 (en) | 2011-04-28 |
CO6160324A2 (es) | 2010-05-20 |
JP5266232B2 (ja) | 2013-08-21 |
US20080132499A1 (en) | 2008-06-05 |
MA30775B1 (fr) | 2009-10-01 |
RU2009114827A (ru) | 2010-10-27 |
IL197726A0 (en) | 2009-12-24 |
WO2008036843A3 (en) | 2008-05-15 |
TN2009000091A1 (en) | 2010-08-19 |
BRPI0718444A2 (pt) | 2013-11-19 |
JP2010504357A (ja) | 2010-02-12 |
CA2664411A1 (en) | 2008-03-27 |
KR20090057314A (ko) | 2009-06-04 |
WO2008036843A2 (en) | 2008-03-27 |
NO20091331L (no) | 2009-05-20 |
US7834023B2 (en) | 2010-11-16 |
MX2009003017A (es) | 2009-06-08 |
AU2007299723A1 (en) | 2008-03-27 |
EP2094272A2 (en) | 2009-09-02 |
NZ576162A (en) | 2012-03-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20190927 |