HK1129045A1 - Chemically modified oligonucleotide primers for nucleic acid amplification - Google Patents

Chemically modified oligonucleotide primers for nucleic acid amplification

Info

Publication number
HK1129045A1
HK1129045A1 HK09108152.8A HK09108152A HK1129045A1 HK 1129045 A1 HK1129045 A1 HK 1129045A1 HK 09108152 A HK09108152 A HK 09108152A HK 1129045 A1 HK1129045 A1 HK 1129045A1
Authority
HK
Hong Kong
Prior art keywords
nucleic acid
acid amplification
oligonucleotide primers
modified oligonucleotide
chemically modified
Prior art date
Application number
HK09108152.8A
Other languages
English (en)
Inventor
Gerald Zon
Alexandre Lebedev
Original Assignee
Trilink Biotechnologies
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Trilink Biotechnologies filed Critical Trilink Biotechnologies
Publication of HK1129045A1 publication Critical patent/HK1129045A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
HK09108152.8A 2006-06-01 2009-09-04 Chemically modified oligonucleotide primers for nucleic acid amplification HK1129045A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81066506P 2006-06-01 2006-06-01
PCT/US2007/011950 WO2007139723A1 (en) 2006-06-01 2007-05-17 Chemicallymodified oligonucleotide primers for nucleic acid amplification

Publications (1)

Publication Number Publication Date
HK1129045A1 true HK1129045A1 (en) 2009-11-13

Family

ID=38778971

Family Applications (1)

Application Number Title Priority Date Filing Date
HK09108152.8A HK1129045A1 (en) 2006-06-01 2009-09-04 Chemically modified oligonucleotide primers for nucleic acid amplification

Country Status (11)

Country Link
US (1) US8361753B2 (de)
EP (1) EP2032714B1 (de)
JP (1) JP5558811B2 (de)
CN (1) CN101517091B (de)
AT (1) ATE502122T1 (de)
AU (1) AU2007268075C1 (de)
CA (1) CA2653841C (de)
DE (1) DE602007013223D1 (de)
ES (1) ES2360738T3 (de)
HK (1) HK1129045A1 (de)
WO (1) WO2007139723A1 (de)

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HUE037173T2 (hu) 2006-08-08 2018-08-28 Univ Bonn Rheinische Friedrich Wilhelms 5'-Foszfát-oligonukleotidok szerkezete és alkalmazása
EP2113574A1 (de) * 2008-04-28 2009-11-04 Biotype AG Stoffe und Verfahren für Profilierungstest auf DNA-Basis
AU2009242546B2 (en) 2008-04-30 2015-01-22 Integrated Dna Technologies, Inc. RNase-H-based assays utilizing modified RNA monomers
US8911948B2 (en) * 2008-04-30 2014-12-16 Integrated Dna Technologies, Inc. RNase H-based assays utilizing modified RNA monomers
JP5689413B2 (ja) 2008-05-21 2015-03-25 ライニッシュ フリードリッヒ−ウィルヘルムズ−ユニバーシタット ボン 平滑末端を有する５’三リン酸オリゴヌクレオチドおよびその使用
ES2625938T3 (es) * 2008-05-27 2017-07-21 Trilink Biotechnologies Nucleósidos 5¿-trifosfatos modificados químicamente para replicación de ácido nucleico iniciada térmicamente
CN101638685B (zh) * 2008-07-29 2013-01-09 杭州优思达生物技术有限公司 交叉引物扩增靶核酸序列的方法及用于扩增靶核酸序列的试剂盒及其应用
EP2382330B1 (de) * 2009-01-06 2015-03-11 Ustar Biotechnologies Ltd Amplifizierung von zielnukleinsäuren mittels cross-priming
WO2011045744A2 (en) * 2009-10-13 2011-04-21 Syntezza Molecular Detection Israel Ltd. Methods and compositions for amplifying target sequences from nucleic acid samples
WO2012094343A1 (en) * 2011-01-05 2012-07-12 Trilink Biotechnologies Chemically substituted thermosensitive probes and cofactors for hot start ligation
AU2012236896A1 (en) 2011-03-25 2013-05-16 Integrated Dna Technologies, Inc. RNase H-based assays utilizing modified RNA monomers
JP2015500204A (ja) * 2011-11-18 2015-01-05 サレプタ セラピューティクス， インコーポレイテッド 機能的に修飾されたオリゴヌクレオチドおよびそのサブユニット
US9353393B2 (en) 2012-02-15 2016-05-31 General Electric Company Methods and kits for reducing non-specific nucleic acid amplification
US9150896B2 (en) * 2012-09-06 2015-10-06 Illumina, Inc. Nucleotides and primers with removable blocking groups
EP2712870A1 (de) 2012-09-27 2014-04-02 Rheinische Friedrich-Wilhelms-Universität Bonn Neuartige RIG-I-Liganden und Herstellungsverfahren dafür
US20160244812A1 (en) 2013-10-07 2016-08-25 Mitsui Chemicals, Inc. Primer set for pcr for bacterial dna amplification, kit for detection and/or identification of bacterial species, and, method of detection and/or identification of bacterial species
US9382582B1 (en) * 2015-08-25 2016-07-05 Tracy Hayden Methods, compositions and kits for enriching for a minor template amplification product in a mixed template amplification reaction
CN108366604A (zh) 2015-09-21 2018-08-03 垂林克生物技术公司 用于合成5’-加帽rna的组合物和方法
WO2017214417A1 (en) * 2016-06-10 2017-12-14 Takara Bio Usa, Inc. Methods and compositions employing blocked primers
US20190169679A1 (en) * 2016-06-23 2019-06-06 Riken One-step reverse transcription template-switching pcr
CN111183223A (zh) 2017-10-12 2020-05-19 三井化学株式会社 mecA基因扩增用引物对、mecA基因检测试剂盒及mecA基因检测方法
EP3837380A4 (de) 2018-08-17 2022-05-11 Cellecta, Inc. Multiplex-präparation von barcodierten genspezifischen dns-fragmenten
JP7328631B2 (ja) 2018-08-24 2023-08-17 Ｒｅｐｅｒｔｏｉｒｅ Ｇｅｎｅｓｉｓ株式会社 Ｔ細胞受容体およびｂ細胞受容体の機能的なサブユニットペア遺伝子の解析方法
CN109680342B (zh) * 2018-12-18 2021-09-28 上海药明康德新药开发有限公司 DNA编码化合物库中On-DNA芳硝基化合物还原成On-DNA芳胺化合物的方法
WO2020214589A1 (en) * 2019-04-17 2020-10-22 Sena Research, Incorporated Modified nucleotides and methods for dna and rna polymerization and sequencing
US11739359B2 (en) 2020-05-01 2023-08-29 Microsoft Technology Licensing, Llc Universal template strands for enzymatic polynucleotide synthesis
US11702683B2 (en) 2020-05-28 2023-07-18 Microsoft Technology Licensing, Llc De novo polynucleotide synthesis with substrate-bound polymerase
AU2023213852A1 (en) 2022-01-27 2024-08-15 Trilink Biotechnologies, Llc Trinucleotide cap analogs and methods of use thereof

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US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US5852188A (en) * 1990-01-11 1998-12-22 Isis Pharmaceuticals, Inc. Oligonucleotides having chiral phosphorus linkages
WO1993014217A1 (en) * 1992-01-10 1993-07-22 Life Technologies, Inc. Use of predetermined nucleotides having altered base pairing characteristics in the amplification of nucleic acid molecules
US5830655A (en) * 1995-05-22 1998-11-03 Sri International Oligonucleotide sizing using cleavable primers
US5773258A (en) * 1995-08-25 1998-06-30 Roche Molecular Systems, Inc. Nucleic acid amplification using a reversibly inactivated thermostable enzyme
US6057134A (en) * 1996-10-07 2000-05-02 Ambion, Inc. Modulating the efficiency of nucleic acid amplification reactions with 3' modified oligonucleotides
US6399304B1 (en) * 1996-12-20 2002-06-04 Roche Diagnostics Gmbh Sequential activation of one or more enzymatic activities within a thermocycling reaction for synthesizing DNA molecules
US6482590B1 (en) * 1996-12-20 2002-11-19 Aventis Behring Gmbh Method for polynucleotide amplification
EP0866071B1 (de) * 1997-03-20 2004-10-20 F. Hoffmann-La Roche Ag Modifizierte Primer
EP1163251A1 (de) * 1999-03-24 2001-12-19 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES N-acylphosphoramiditen und ihre verwendung in oligonukleotidsynthesen
US6274353B1 (en) * 1999-09-22 2001-08-14 Genecopoeia, Inc. Method and compositions for improved polynucleotide synthesis
AU2001253129A1 (en) 2000-04-03 2001-10-15 Biolink Partners, Inc. Reversible chemical modification of nucleic acids and improved method for nucleic acid hybridization
WO2002018616A1 (en) 2000-09-01 2002-03-07 Hitachi Chemical Co., Ltd. Adjusting the efficiency of nucleic acid template amplification by attenuated pcr with template-mimic oligonucleotides
US6743905B2 (en) * 2001-04-16 2004-06-01 Applera Corporation Mobility-modified nucleobase polymers and methods of using same
GB0110501D0 (en) 2001-04-30 2001-06-20 Secr Defence Brit Amplification process
EP1275735A1 (de) 2001-07-11 2003-01-15 Roche Diagnostics GmbH Zusammensetzung und Methode zur 'Hot start' Nukleinsäureamplifizierung
US7700281B2 (en) 2004-06-30 2010-04-20 Usb Corporation Hot start nucleic acid amplification
GB2416352B (en) 2004-07-21 2009-01-28 Bioline Ltd A method for performing the hot start of enzymatic reactions
WO2006074217A2 (en) * 2005-01-04 2006-07-13 Stratagene California Hot start polymerase reaction using a thermolabile blocker
EP2405024A1 (de) 2005-07-15 2012-01-11 Life Technologies Corporation Heissstart reverse Transkription durch primer design

Also Published As

Publication number Publication date
DE602007013223D1 (de) 2011-04-28
ATE502122T1 (de) 2011-04-15
WO2007139723A8 (en) 2009-12-17
CN101517091B (zh) 2013-02-13
US20070281308A1 (en) 2007-12-06
JP2009538621A (ja) 2009-11-12
ES2360738T3 (es) 2011-06-08
AU2007268075B2 (en) 2012-09-13
EP2032714B1 (de) 2011-03-16
AU2007268075A1 (en) 2007-12-06
CA2653841A1 (en) 2007-12-06
EP2032714A4 (de) 2009-12-23
WO2007139723A1 (en) 2007-12-06
EP2032714A1 (de) 2009-03-11
JP5558811B2 (ja) 2014-07-23
CN101517091A (zh) 2009-08-26
CA2653841C (en) 2016-07-19
US8361753B2 (en) 2013-01-29
AU2007268075C1 (en) 2013-03-07

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