HK1128285A1 - Substituted indolyl-alkyl-amino-derivatives as inhibitors of histone deacetylase - Google Patents

Substituted indolyl-alkyl-amino-derivatives as inhibitors of histone deacetylase

Info

Publication number
HK1128285A1
HK1128285A1 HK09105787.7A HK09105787A HK1128285A1 HK 1128285 A1 HK1128285 A1 HK 1128285A1 HK 09105787 A HK09105787 A HK 09105787A HK 1128285 A1 HK1128285 A1 HK 1128285A1
Authority
HK
Hong Kong
Prior art keywords
inhibitors
derivatives
amino
alkyl
histone deacetylase
Prior art date
Application number
HK09105787.7A
Other languages
English (en)
Inventor
Patrick Rene Angibaud
Isabelle Noelle Constance Pilatte
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of HK1128285A1 publication Critical patent/HK1128285A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK09105787.7A 2006-01-19 2009-06-26 Substituted indolyl-alkyl-amino-derivatives as inhibitors of histone deacetylase HK1128285A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06100576 2006-01-19
PCT/EP2007/050381 WO2007082882A1 (en) 2006-01-19 2007-01-16 Substituted indolyl-alkyl-amino-derivatives as inhibitors of histone deacetylase

Publications (1)

Publication Number Publication Date
HK1128285A1 true HK1128285A1 (en) 2009-10-23

Family

ID=36572342

Family Applications (1)

Application Number Title Priority Date Filing Date
HK09105787.7A HK1128285A1 (en) 2006-01-19 2009-06-26 Substituted indolyl-alkyl-amino-derivatives as inhibitors of histone deacetylase

Country Status (10)

Country Link
US (2) US7834025B2 (xx)
EP (1) EP1981875B1 (xx)
JP (1) JP5137849B2 (xx)
CN (1) CN101370803B (xx)
AU (1) AU2007206950B2 (xx)
CA (1) CA2635015C (xx)
DK (1) DK1981875T3 (xx)
ES (1) ES2481408T3 (xx)
HK (1) HK1128285A1 (xx)
WO (1) WO2007082882A1 (xx)

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BR0307607A (pt) * 2002-03-13 2004-12-21 Janssen Pharmaceutica Nv Derivados de carbonilamino como inibidores de histona desacetilase
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KR101261305B1 (ko) 2004-07-28 2013-05-08 얀센 파마슈티카 엔.브이. 히스톤 디아세틸라제의 신규한 저해제로의 치환된 인돌릴알킬 아미노 유도체
ME01058B (me) * 2004-07-28 2012-10-20 Janssen Pharmaceutica Nv Supstituisani derivati propenil piperazina kao novi inhibitori histonske deacetilaze
JP5055268B2 (ja) 2005-05-18 2012-10-24 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ ヒストンデアセチラーゼの新規な阻害剤としての置換されたアミノプロペニルピペリジンまたはモルホリン誘導体
AU2006307918B2 (en) * 2005-10-27 2012-06-21 Janssen Pharmaceutica N.V. Squaric acid derivatives as inhibitors of histone deacetylase
US7888360B2 (en) * 2006-01-19 2011-02-15 Janssen Pharmaceutica N.V. Pyridine and pyrimidine derivatives as inhibitors of histone deacetylase
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WO2012096832A2 (en) * 2011-01-12 2012-07-19 Crystal Biopharmaceutical Llc Hdac inhibiting derivatives of camptothecin
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CA2903490C (en) 2013-03-15 2021-04-13 Biomarin Pharmaceutical Inc. Hdac inhibitors
KR20220137085A (ko) 2020-02-04 2022-10-11 마인드셋 파마 인크. Cns 장애의 치료를 위한 세로토닌성 사이키델릭 작용제로서의 3-피롤리딘-인돌 유도체
JP7531371B2 (ja) 2020-11-17 2024-08-09 Ｄｉｃグラフィックス株式会社 活性エネルギー線硬化型オーバーコートニス、及び積層体
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Also Published As

Publication number Publication date
CA2635015A1 (en) 2007-07-26
ES2481408T3 (es) 2014-07-30
JP5137849B2 (ja) 2013-02-06
EP1981875B1 (en) 2014-04-16
US8163765B2 (en) 2012-04-24
JP2009523761A (ja) 2009-06-25
US7834025B2 (en) 2010-11-16
AU2007206950B2 (en) 2012-02-02
US20090018153A1 (en) 2009-01-15
US20110118291A1 (en) 2011-05-19
CA2635015C (en) 2014-06-03
CN101370803A (zh) 2009-02-18
DK1981875T3 (da) 2014-07-14
WO2007082882A1 (en) 2007-07-26
AU2007206950A1 (en) 2007-07-26
CN101370803B (zh) 2012-12-12
EP1981875A1 (en) 2008-10-22

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Effective date: 20180116