HK1125293A1 - Immediate release therapeutic systems for improved oral absorption of 7- [(e)-tertbutyloxyiminoxmethyl] camptothecin 7-[(e)-] - Google Patents

Immediate release therapeutic systems for improved oral absorption of 7- [(e)-tertbutyloxyiminoxmethyl] camptothecin 7-[(e)-]

Info

Publication number
HK1125293A1
HK1125293A1 HK09103194.9A HK09103194A HK1125293A1 HK 1125293 A1 HK1125293 A1 HK 1125293A1 HK 09103194 A HK09103194 A HK 09103194A HK 1125293 A1 HK1125293 A1 HK 1125293A1
Authority
HK
Hong Kong
Prior art keywords
tertbutyloxyiminoxmethyl
camptothecin
immediate release
oral absorption
therapeutic systems
Prior art date
Application number
HK09103194.9A
Other languages
English (en)
Chinese (zh)
Inventor
‧隆哥
‧帕切
‧佩德拉尼
Original Assignee
希格馬托製藥工業公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 希格馬托製藥工業公司 filed Critical 希格馬托製藥工業公司
Publication of HK1125293A1 publication Critical patent/HK1125293A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
HK09103194.9A 2005-08-04 2009-04-03 Immediate release therapeutic systems for improved oral absorption of 7- [(e)-tertbutyloxyiminoxmethyl] camptothecin 7-[(e)-] HK1125293A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000418A ITRM20050418A1 (it) 2005-08-04 2005-08-04 Sistemi terapeutici a rilascio immediato per il migliorato assorbimento orale di 7-[(e)-t-butilossimminometil] camptotecina.
PCT/EP2006/064111 WO2007017331A2 (fr) 2005-08-04 2006-07-11 Systemes therapeutiques a liberation immediate pour une meilleure absorption par voie orale de la 7-[(e)]-t-butyloxyminomethyle] camptothecine

Publications (1)

Publication Number Publication Date
HK1125293A1 true HK1125293A1 (en) 2009-08-07

Family

ID=37727667

Family Applications (1)

Application Number Title Priority Date Filing Date
HK09103194.9A HK1125293A1 (en) 2005-08-04 2009-04-03 Immediate release therapeutic systems for improved oral absorption of 7- [(e)-tertbutyloxyiminoxmethyl] camptothecin 7-[(e)-]

Country Status (20)

Country Link
US (1) US20090053307A1 (fr)
EP (1) EP1915153B1 (fr)
JP (1) JP5225084B2 (fr)
KR (1) KR101301548B1 (fr)
CN (1) CN101287466B (fr)
AU (1) AU2006278114B2 (fr)
BR (1) BRPI0614471A2 (fr)
CA (1) CA2612080C (fr)
CY (1) CY1114311T1 (fr)
DK (1) DK1915153T3 (fr)
ES (1) ES2407408T3 (fr)
HK (1) HK1125293A1 (fr)
HR (1) HRP20130364T1 (fr)
IT (1) ITRM20050418A1 (fr)
MX (1) MX2008001029A (fr)
PL (1) PL1915153T3 (fr)
PT (1) PT1915153E (fr)
RS (1) RS52777B (fr)
SI (1) SI1915153T1 (fr)
WO (1) WO2007017331A2 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2519193C2 (ru) 2008-09-12 2014-06-10 Критикал Фармасьютикалс Лимитед Усовершенствование всасывания терапевтических средств через слизистые оболочки или кожу
US7892036B2 (en) * 2008-12-30 2011-02-22 Multiway Industries (Hk) Ltd. Electrical wall tap assembly
USD618617S1 (en) 2008-12-30 2010-06-29 Multiway Industries (Hk) Ltd. Three way electrical plug
USD618175S1 (en) 2009-10-15 2010-06-22 Multiway Industries (Hk) Ltd. Three-outlet surge-protected adaptor
USD616823S1 (en) 2009-10-15 2010-06-01 Multiway Industries (Hk) Ltd. Single-outlet surge-protected adaptor
CN102740841A (zh) * 2009-12-08 2012-10-17 株式会社一和 含有20-O-β-D-吡喃葡糖基-20(S)-原人参二醇的固体分散体
USD651977S1 (en) 2011-01-10 2012-01-10 Multiway Industries (Hk) Ltd. Multiple outlet electrical connector
CN108066311B (zh) * 2017-12-26 2020-09-08 兆科（广州）肿瘤药物有限公司 一种吉马替康胶囊及其制备方法
USD958079S1 (en) 2019-08-30 2022-07-19 Multiway Industries (Hk) Ltd. 3-way electrical tap
USD955993S1 (en) 2019-08-30 2022-06-28 Multiway Industries (Hk) Ltd. 3-way electrical tap
CN111529497A (zh) * 2020-02-11 2020-08-14 兆科（广州）肿瘤药物有限公司 一种吉马替康药物固体分散组合物及其制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5726181A (en) * 1995-06-05 1998-03-10 Bionumerik Pharmaceuticals, Inc. Formulations and compositions of poorly water soluble camptothecin derivatives
DE69823663T2 (de) * 1997-07-29 2005-05-19 Pharmacia & Upjohn Co., Kalamazoo Selbstemulgierbare formulierung enthaltend lipophile verbindungen
AR013261A1 (es) * 1997-08-01 2000-12-13 Smithkline Beecham Corp Formulaciones farmaceuticas para analogos de camptotecina en capsula de gelatina
US7030155B2 (en) * 1998-06-05 2006-04-18 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
ATE216998T1 (de) * 1999-03-09 2002-05-15 Sigma Tau Ind Farmaceuti Camptothecin-derivate mit antitumor-wirkung
KR20070058028A (ko) * 1999-05-24 2007-06-07 소너스파머슈티칼즈인코포레이티드 난용성 약물용 에멀젼 부형제
RU2006137657A (ru) * 2004-03-26 2008-05-10 Новартис АГ (CH) Применение производных камптотецина для лечения пролиферативных заболеваний с использованием схемы лечения с фиксированной дозой
GT200500310A (es) * 2004-11-19 2006-06-19 Compuestos organicos
WO2006067092A2 (fr) * 2004-12-21 2006-06-29 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Methode stereoselective et formes cristallines d'une camptothecine

Also Published As

Publication number Publication date
EP1915153A2 (fr) 2008-04-30
AU2006278114B2 (en) 2011-06-23
HRP20130364T1 (hr) 2013-05-31
DK1915153T3 (da) 2013-06-24
EP1915153B1 (fr) 2013-04-10
ES2407408T3 (es) 2013-06-12
WO2007017331A2 (fr) 2007-02-15
CN101287466B (zh) 2014-11-05
PL1915153T3 (pl) 2013-09-30
US20090053307A1 (en) 2009-02-26
KR101301548B1 (ko) 2013-09-06
PT1915153E (pt) 2013-06-05
WO2007017331A3 (fr) 2007-09-27
KR20080031945A (ko) 2008-04-11
CA2612080A1 (fr) 2007-02-15
ITRM20050418A1 (it) 2007-02-05
JP5225084B2 (ja) 2013-07-03
BRPI0614471A2 (pt) 2011-03-29
CY1114311T1 (el) 2016-08-31
JP2009503013A (ja) 2009-01-29
RS52777B (en) 2013-10-31
AU2006278114A1 (en) 2007-02-15
CA2612080C (fr) 2013-09-03
CN101287466A (zh) 2008-10-15
MX2008001029A (es) 2008-03-14
SI1915153T1 (sl) 2013-06-28

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