HK1125293A1 - 用於改善 -叔丁氧亞氨基甲基 喜樹鹼經口吸收的即釋治療系統 - Google Patents

用於改善 -叔丁氧亞氨基甲基 喜樹鹼經口吸收的即釋治療系統

Info

Publication number
HK1125293A1
HK1125293A1 HK09103194.9A HK09103194A HK1125293A1 HK 1125293 A1 HK1125293 A1 HK 1125293A1 HK 09103194 A HK09103194 A HK 09103194A HK 1125293 A1 HK1125293 A1 HK 1125293A1
Authority
HK
Hong Kong
Prior art keywords
tertbutyloxyiminoxmethyl
camptothecin
immediate release
oral absorption
therapeutic systems
Prior art date
Application number
HK09103194.9A
Other languages
English (en)
Inventor
‧隆哥
‧帕切
‧佩德拉尼
Original Assignee
希格馬托製藥工業公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 希格馬托製藥工業公司 filed Critical 希格馬托製藥工業公司
Publication of HK1125293A1 publication Critical patent/HK1125293A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK09103194.9A 2005-08-04 2009-04-03 用於改善 -叔丁氧亞氨基甲基 喜樹鹼經口吸收的即釋治療系統 HK1125293A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000418A ITRM20050418A1 (it) 2005-08-04 2005-08-04 Sistemi terapeutici a rilascio immediato per il migliorato assorbimento orale di 7-[(e)-t-butilossimminometil] camptotecina.
PCT/EP2006/064111 WO2007017331A2 (en) 2005-08-04 2006-07-11 Immediate release therapeutic systems for improved oral absorption of 7- [ (e) -tert-butyloxyiminomethyl] camptothecin

Publications (1)

Publication Number Publication Date
HK1125293A1 true HK1125293A1 (zh) 2009-08-07

Family

ID=37727667

Family Applications (1)

Application Number Title Priority Date Filing Date
HK09103194.9A HK1125293A1 (zh) 2005-08-04 2009-04-03 用於改善 -叔丁氧亞氨基甲基 喜樹鹼經口吸收的即釋治療系統

Country Status (20)

Country Link
US (1) US20090053307A1 (zh)
EP (1) EP1915153B1 (zh)
JP (1) JP5225084B2 (zh)
KR (1) KR101301548B1 (zh)
CN (1) CN101287466B (zh)
AU (1) AU2006278114B2 (zh)
BR (1) BRPI0614471A2 (zh)
CA (1) CA2612080C (zh)
CY (1) CY1114311T1 (zh)
DK (1) DK1915153T3 (zh)
ES (1) ES2407408T3 (zh)
HK (1) HK1125293A1 (zh)
HR (1) HRP20130364T1 (zh)
IT (1) ITRM20050418A1 (zh)
MX (1) MX2008001029A (zh)
PL (1) PL1915153T3 (zh)
PT (1) PT1915153E (zh)
RS (1) RS52777B (zh)
SI (1) SI1915153T1 (zh)
WO (1) WO2007017331A2 (zh)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0918253A2 (pt) 2008-09-12 2015-12-15 Critical Pharmaceuticals Ltd aperfeicoamento na absorcao de agentes terapeuticos atraves das membranas mucosas ou da pele
US7892036B2 (en) * 2008-12-30 2011-02-22 Multiway Industries (Hk) Ltd. Electrical wall tap assembly
USD618617S1 (en) 2008-12-30 2010-06-29 Multiway Industries (Hk) Ltd. Three way electrical plug
USD616823S1 (en) 2009-10-15 2010-06-01 Multiway Industries (Hk) Ltd. Single-outlet surge-protected adaptor
USD618175S1 (en) 2009-10-15 2010-06-22 Multiway Industries (Hk) Ltd. Three-outlet surge-protected adaptor
JP2013512948A (ja) * 2009-12-08 2013-04-18 イル・ファ・カンパニー・リミテッド ２０−Ｏ−β−Ｄ−グルコピラノシル−２０（Ｓ）−プロトパナキサジオールを含む固体分散体
USD651977S1 (en) 2011-01-10 2012-01-10 Multiway Industries (Hk) Ltd. Multiple outlet electrical connector
CN108066311B (zh) * 2017-12-26 2020-09-08 兆科（广州）肿瘤药物有限公司 一种吉马替康胶囊及其制备方法
USD955993S1 (en) 2019-08-30 2022-06-28 Multiway Industries (Hk) Ltd. 3-way electrical tap
USD958079S1 (en) 2019-08-30 2022-07-19 Multiway Industries (Hk) Ltd. 3-way electrical tap
CN111529497A (zh) * 2020-02-11 2020-08-14 兆科（广州）肿瘤药物有限公司 一种吉马替康药物固体分散组合物及其制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5726181A (en) * 1995-06-05 1998-03-10 Bionumerik Pharmaceuticals, Inc. Formulations and compositions of poorly water soluble camptothecin derivatives
CN1208047C (zh) * 1997-07-29 2005-06-29 法玛西雅厄普约翰美国公司 亲脂性化合物的自体乳化剂
AR013261A1 (es) * 1997-08-01 2000-12-13 Smithkline Beecham Corp Formulaciones farmaceuticas para analogos de camptotecina en capsula de gelatina
US7030155B2 (en) * 1998-06-05 2006-04-18 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
DE69901379T2 (de) * 1999-03-09 2002-11-07 Sigma Tau Ind Farmaceuti Camptothecin-Derivate mit Antitumor-Wirkung
JP2003500368A (ja) * 1999-05-24 2003-01-07 ソーナス ファーマシューティカルス，インコーポレイテッド 溶解度が不十分な薬剤のためのエマルジョンビヒクル
WO2005092302A2 (en) * 2004-03-26 2005-10-06 Novartis Ag Use of camptothecin derivates for the treatment of proliferative diseases in a fixed dosing regimen
GT200500310A (es) * 2004-11-19 2006-06-19 Compuestos organicos
AU2005318227B2 (en) * 2004-12-21 2011-08-18 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Stereoselective process and crystalline forms of a camptothecin

Also Published As

Publication number Publication date
CN101287466B (zh) 2014-11-05
JP5225084B2 (ja) 2013-07-03
DK1915153T3 (da) 2013-06-24
CA2612080C (en) 2013-09-03
WO2007017331A3 (en) 2007-09-27
RS52777B (en) 2013-10-31
KR20080031945A (ko) 2008-04-11
EP1915153A2 (en) 2008-04-30
HRP20130364T1 (hr) 2013-05-31
BRPI0614471A2 (pt) 2011-03-29
CY1114311T1 (el) 2016-08-31
SI1915153T1 (sl) 2013-06-28
MX2008001029A (es) 2008-03-14
CA2612080A1 (en) 2007-02-15
US20090053307A1 (en) 2009-02-26
WO2007017331A2 (en) 2007-02-15
PT1915153E (pt) 2013-06-05
ES2407408T3 (es) 2013-06-12
KR101301548B1 (ko) 2013-09-06
JP2009503013A (ja) 2009-01-29
AU2006278114B2 (en) 2011-06-23
CN101287466A (zh) 2008-10-15
PL1915153T3 (pl) 2013-09-30
AU2006278114A1 (en) 2007-02-15
ITRM20050418A1 (it) 2007-02-05
EP1915153B1 (en) 2013-04-10

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