HK1111360A1 - Toll like receptor 3 antagonists, methods and uses toll 3 - Google Patents
Toll like receptor 3 antagonists, methods and uses toll 3Info
- Publication number
- HK1111360A1 HK1111360A1 HK08102121.0A HK08102121A HK1111360A1 HK 1111360 A1 HK1111360 A1 HK 1111360A1 HK 08102121 A HK08102121 A HK 08102121A HK 1111360 A1 HK1111360 A1 HK 1111360A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- toll
- antagonists
- receptor
- methods
- uses toll
- Prior art date
Links
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- C—CHEMISTRY; METALLURGY
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- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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- C—CHEMISTRY; METALLURGY
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Vascular Medicine (AREA)
- Endocrinology (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US63181504P | 2004-11-30 | 2004-11-30 | |
US63639904P | 2004-12-15 | 2004-12-15 | |
US64187705P | 2005-01-06 | 2005-01-06 | |
US71319505P | 2005-08-31 | 2005-08-31 | |
US72761005P | 2005-10-18 | 2005-10-18 | |
PCT/US2005/043373 WO2006060513A2 (en) | 2004-11-30 | 2005-11-30 | Toll like receptor 3 antagonists, methods and uses |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1111360A1 true HK1111360A1 (en) | 2008-08-08 |
Family
ID=36565702
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK08102121.0A HK1111360A1 (en) | 2004-11-30 | 2008-02-26 | Toll like receptor 3 antagonists, methods and uses toll 3 |
HK09109752.0A HK1131744A1 (en) | 2004-11-30 | 2009-10-21 | Toll like receptor 3 antagonists, methods and uses toll |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK09109752.0A HK1131744A1 (en) | 2004-11-30 | 2009-10-21 | Toll like receptor 3 antagonists, methods and uses toll |
Country Status (16)
Country | Link |
---|---|
US (1) | US8153583B2 (ja) |
EP (2) | EP1824514B1 (ja) |
JP (2) | JP5039560B2 (ja) |
KR (1) | KR101317264B1 (ja) |
AR (1) | AR051836A1 (ja) |
AU (1) | AU2005311894A1 (ja) |
BR (1) | BRPI0518664A2 (ja) |
CA (1) | CA2589636C (ja) |
EA (1) | EA200701192A1 (ja) |
HK (2) | HK1111360A1 (ja) |
IL (1) | IL183541A (ja) |
MX (1) | MX2007006442A (ja) |
NO (1) | NO20073293L (ja) |
NZ (1) | NZ555475A (ja) |
TW (1) | TWI487535B (ja) |
WO (1) | WO2006060513A2 (ja) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0121591D0 (en) | 2001-09-06 | 2001-10-24 | Chiron Spa | Hybrid and tandem expression of neisserial proteins |
ES2435775T3 (es) * | 2005-10-27 | 2013-12-23 | Janssen Biotech, Inc. | Moduladores de receptor tipo Toll 3, procedimientos y usos |
US8066981B2 (en) * | 2006-11-14 | 2011-11-29 | The Texas A & M University System | Compositions and methods related to toll-like receptor-3 |
JP2010527633A (ja) * | 2007-05-25 | 2010-08-19 | セントコア・オーソ・バイオテツク・インコーポレーテツド | Toll様受容体3モジュレーター及びその使用 |
WO2009071696A2 (en) | 2007-12-07 | 2009-06-11 | Zymogenetics, Inc. | Humanized antibody molecules specific for il-31 |
CA2710760C (en) * | 2007-12-26 | 2017-05-16 | Centocor Ortho Biotech Inc. | Cynomolgus toll-like receptor 3 |
US20100105875A1 (en) * | 2008-06-09 | 2010-04-29 | Maria Scarselli | Antibodies against neisserial factor H binding protein |
DE602008004898D1 (de) * | 2008-06-27 | 2011-03-24 | Theranor Sprl | Pharmazeutische Zusammensetzungen von Antikörpern von Viruserkrankungen |
US8895263B2 (en) * | 2008-10-02 | 2014-11-25 | Janssen Biotech, Inc. | Methods for suppressing toll-like receptor activity |
US8460659B2 (en) | 2008-10-31 | 2013-06-11 | Janssen Biotech, Inc. | Toll-like receptor 3 antagonists for the treatment of metabolic and cardiovascular diseases |
KR101683033B1 (ko) * | 2008-10-31 | 2016-12-06 | 얀센 바이오테크 인코포레이티드 | 톨-유사 수용체 3 길항제 |
US20100135983A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Anti-inflammatory compositions and methods |
US20100137246A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Anti-inflammatory compositions and methods |
US20100137247A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Anti-inflammatory compositions and methods |
US20100136097A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Systems for modulating inflammation |
US20100136095A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Systems for modulating inflammation |
US20100136094A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Systems for modulating inflammation |
US20100136096A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Systems for modulating inflammation |
DK2425008T3 (en) * | 2009-04-29 | 2015-10-05 | Janssen Biotech Inc | Toll-like receptor antagonists 3 |
AU2010270163B2 (en) * | 2009-07-10 | 2016-05-05 | Innate Pharma, S.A. | TLR3 binding agents |
CN102639700A (zh) | 2009-09-30 | 2012-08-15 | 哈佛大学校长及研究员协会 | 通过调节自噬增强基因产物调节自噬的方法 |
CA2824313A1 (en) | 2011-01-12 | 2012-07-19 | Innate Pharma | Tlr3 binding agents |
PE20141521A1 (es) * | 2011-08-23 | 2014-10-25 | Roche Glycart Ag | Moleculas biespecificas de union a antigeno activadoras de celulas t |
WO2013026837A1 (en) * | 2011-08-23 | 2013-02-28 | Roche Glycart Ag | Bispecific t cell activating antigen binding molecules |
CA2855955A1 (en) | 2011-09-12 | 2013-03-21 | Janssen Biotech, Inc. | Toll-like receptor 3 antagonists |
DK2855527T3 (en) * | 2012-05-31 | 2018-11-26 | Innate Pharma | TLR3 BINDERS |
TWI682941B (zh) | 2013-02-01 | 2020-01-21 | 美商再生元醫藥公司 | 含嵌合恆定區之抗體 |
ES2775207T3 (es) | 2013-02-26 | 2020-07-24 | Roche Glycart Ag | Moléculas de unión a antígeno activadoras de linfocitos T biespecíficas específicas para CD3 y CEA |
US9198898B2 (en) | 2013-06-24 | 2015-12-01 | Tigercat Pharma, Inc. | Use of NK-1 receptor antagonists in pruritus |
US8906951B1 (en) | 2013-06-24 | 2014-12-09 | Tigercat Pharma, Inc. | Use of NK-1 receptor antagonists in pruritus |
TWI754319B (zh) | 2014-03-19 | 2022-02-01 | 美商再生元醫藥公司 | 用於腫瘤治療之方法及抗體組成物 |
EP3699198A1 (en) | 2014-11-17 | 2020-08-26 | Regeneron Pharmaceuticals, Inc. | Methods for tumor treatment using cd3xcd20 bispecific antibody |
US10556952B2 (en) | 2015-03-30 | 2020-02-11 | Regeneron Pharmaceuticals, Inc. | Heavy chain constant regions with reduced binding to Fc gamma receptors |
EP3356410B1 (en) | 2015-10-02 | 2021-10-20 | F. Hoffmann-La Roche AG | Bispecific anti-ceaxcd3 t cell activating antigen binding molecules |
AU2016368469B2 (en) | 2015-12-09 | 2023-11-02 | F. Hoffmann-La Roche Ag | Type II anti-CD20 antibody for reducing formation of anti-drug antibodies |
AR107303A1 (es) | 2016-01-08 | 2018-04-18 | Hoffmann La Roche | Métodos de tratamiento de cánceres positivos para ace utilizando antagonistas de unión a eje pd-1 y anticuerpos biespecíficos anti-ace / anti-cd3, uso, composición, kit |
US20230041197A1 (en) | 2018-06-20 | 2023-02-09 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immunomodulator |
US20230009902A1 (en) | 2018-06-20 | 2023-01-12 | Progenity, Inc. | Treatment of a disease or condition in a tissue orginating from the endoderm |
CA3110513A1 (en) | 2018-08-31 | 2020-03-05 | Regeneron Pharmaceuticals, Inc. | Dosing strategy that mitigates cytokine release syndrome for cd3/c20 bispecific antibodies |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
US5225539A (en) * | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
CA2289912C (en) | 1997-05-07 | 2011-07-26 | Schering Corporation | Human receptor proteins; related reagents and methods |
US20030032090A1 (en) * | 1997-05-07 | 2003-02-13 | Schering Corporation, A New Jersey Corporation | Human receptor proteins; related reagents and methods |
DE60035262T2 (de) | 1999-03-09 | 2008-02-21 | Anker, Stefan, Prof. Dr. | Endotoxinhemmern zur behandlung von kachexie |
GB9930616D0 (en) | 1999-12-24 | 2000-02-16 | Mathilda & Terence Kennedy Ins | Activation and inhibition of the immune system |
WO2003022296A1 (en) * | 2001-09-07 | 2003-03-20 | The Trustees Of Boston University | Method and composition for treating immune complex associated disorders |
IL160837A0 (en) | 2001-10-05 | 2004-08-31 | Coley Pharm Gmbh | Toll-like receptor 3 signaling agonists and antagonists |
WO2003084527A1 (fr) | 2002-04-08 | 2003-10-16 | Takeda Chemical Industries, Ltd. | Agent therapeutique pour la prevention d'etat septique grave |
JP2004016021A (ja) * | 2002-06-12 | 2004-01-22 | Japan Science & Technology Corp | 抗体および阻害剤並びにそれを用いた形質転換方法および形質転換キット |
CA2528774A1 (en) * | 2003-06-20 | 2005-01-27 | Coley Pharmaceutical Gmbh | Small molecule toll-like receptor (tlr) antagonists |
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US8153583B2 (en) | 2012-04-10 |
TWI487535B (zh) | 2015-06-11 |
MX2007006442A (es) | 2007-10-23 |
EA200701192A1 (ru) | 2009-12-30 |
HK1131744A1 (en) | 2010-02-05 |
WO2006060513A2 (en) | 2006-06-08 |
TW200631594A (en) | 2006-09-16 |
US20060115475A1 (en) | 2006-06-01 |
EP2481425A1 (en) | 2012-08-01 |
EP1824514A2 (en) | 2007-08-29 |
AR051836A1 (es) | 2007-02-14 |
JP2012149092A (ja) | 2012-08-09 |
EP1824514A4 (en) | 2009-11-18 |
WO2006060513A3 (en) | 2009-05-14 |
AU2005311894A1 (en) | 2006-06-08 |
CA2589636C (en) | 2015-03-24 |
KR101317264B1 (ko) | 2013-10-15 |
IL183541A (en) | 2011-10-31 |
BRPI0518664A2 (pt) | 2008-12-02 |
JP5039560B2 (ja) | 2012-10-03 |
KR20070090969A (ko) | 2007-09-06 |
CA2589636A1 (en) | 2006-06-08 |
NO20073293L (no) | 2007-08-17 |
EP1824514B1 (en) | 2015-03-04 |
IL183541A0 (en) | 2007-09-20 |
NZ555475A (en) | 2010-12-24 |
JP2008521440A (ja) | 2008-06-26 |
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