HK1100181A1 - Expression in filamentous fungi of protease inhibitors and variants thereof - Google Patents

Expression in filamentous fungi of protease inhibitors and variants thereof

Info

Publication number
HK1100181A1
HK1100181A1 HK07105837.9A HK07105837A HK1100181A1 HK 1100181 A1 HK1100181 A1 HK 1100181A1 HK 07105837 A HK07105837 A HK 07105837A HK 1100181 A1 HK1100181 A1 HK 1100181A1
Authority
HK
Hong Kong
Prior art keywords
variants
expression
protease inhibitors
filamentous fungi
filamentous
Prior art date
Application number
HK07105837.9A
Other languages
English (en)
Inventor
Nobel Hans De
David A Estell
Wei Liu
Scott D Power
Brian Schmidt
Huaming Wang
Original Assignee
Genencor Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genencor Int filed Critical Genencor Int
Publication of HK1100181A1 publication Critical patent/HK1100181A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/8107Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811Serine protease (E.C. 3.4.21) inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
HK07105837.9A 2003-11-06 2007-06-01 Expression in filamentous fungi of protease inhibitors and variants thereof HK1100181A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51815403P 2003-11-06 2003-11-06
PCT/US2004/035278 WO2005047302A1 (en) 2003-11-06 2004-10-22 Expression in filamentous fungi of protease inhibitors and variants thereof

Publications (1)

Publication Number Publication Date
HK1100181A1 true HK1100181A1 (en) 2007-09-07

Family

ID=34590229

Family Applications (1)

Application Number Title Priority Date Filing Date
HK07105837.9A HK1100181A1 (en) 2003-11-06 2007-06-01 Expression in filamentous fungi of protease inhibitors and variants thereof

Country Status (10)

Country Link
US (3) US7279564B2 (xx)
EP (2) EP1689766B1 (xx)
JP (1) JP4834554B2 (xx)
KR (3) KR101348530B1 (xx)
CN (2) CN101857867A (xx)
AT (1) ATE555119T1 (xx)
CA (1) CA2545053C (xx)
DK (1) DK1689766T3 (xx)
HK (1) HK1100181A1 (xx)
WO (1) WO2005047302A1 (xx)

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EP1692158B1 (en) * 2003-11-06 2011-10-26 Danisco US Inc. Vegf binding and supported peptides for treating skin diseases
EP1869160A2 (en) * 2005-04-12 2007-12-26 Genencor International, Inc. Gene inactivated mutants with altered protein production
AU2006316838B2 (en) * 2005-11-15 2012-04-12 Glycofi, Inc Production of glycoproteins with reduced O-glycosylation
US20080026376A1 (en) 2006-07-11 2008-01-31 Huaming Wang KEX2 cleavage regions of recombinant fusion proteins
US8198046B2 (en) * 2006-07-11 2012-06-12 Danisco Us Inc. KEX2 cleavage regions of recombinant fusion proteins
EP2092113A2 (en) * 2006-12-18 2009-08-26 Danisco US, INC., Genencor Division Laccase mediators and methods of use
CA2704548A1 (en) * 2007-11-01 2009-05-07 Danisco Us Inc. Signal sequences and co-expressed chaperones for improving protein production in a host cell
US7772181B2 (en) 2008-10-15 2010-08-10 Danisco Us Inc. Personal care compositions comprising modified variant Bowman Birk Protease Inhibitors
CA2740197A1 (en) * 2008-10-15 2010-04-22 Danisco Us Inc. Modified variant bowman birk protease inhibitors
US7803902B2 (en) 2008-10-15 2010-09-28 Danisco Us Inc. Modified variant bowman birk protease inhibitors
GB0921001D0 (en) * 2009-11-30 2010-01-13 Aqua Bio Technology Asa Products and uses
US20120289683A1 (en) * 2009-12-30 2012-11-15 Solae, Llc Purified Kunitz Trypsin Inhibitor Proteins Isolated from a Soy Processing Stream
US10266832B2 (en) * 2010-08-25 2019-04-23 Danisco Us Inc Filamentous fungi having an altered viscosity phenotype
EP2643468B1 (en) * 2010-11-22 2018-07-04 Amicus Therapeutics, Inc. Novel signal sequences to improve protein expressions and secretion of recombinant enzymes and other proteins
EP2699667B1 (en) * 2011-04-22 2016-04-13 Danisco US Inc. Filamentous fungi having an altered viscosity phenotype
US9434934B2 (en) * 2013-07-29 2016-09-06 Academia Sinica Heat stable keratinase and use thereof
JP6544503B2 (ja) * 2014-01-30 2019-07-17 福岡県 コラゲナーゼ阻害剤、並びにコラゲナーゼ阻害剤を配合した化粧料組成物及び機能性食品
BR112021006829A2 (pt) 2018-10-10 2021-07-20 Amicus Therapeutics, Inc. composições de polipeptídeos estabilizados com ligações dissulfeto e métodos de uso
CR20220013A (es) * 2019-06-26 2022-05-20 Eg Crop Science Inc Identificación de genes de resistencia a partir de parientes silvestres del plátano y sus usos en el control del mal de panamá
CN112553274B (zh) * 2020-12-02 2023-06-13 江南大学 大豆提取物Bowman-Birk inhibitor切割DNA的方法

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US214237A (en) 1879-04-15 Improvement in grain-driers
DE3009104C2 (de) * 1980-03-10 1990-10-04 Odenwald-Chemie GmbH, 6901 Schönau Verwendung eines Epoxydharzes zur Herstellung von feuerhemmenden Schichten oder Überzügen und Verfahren zur Herstellung derselben
CA1338400C (en) 1983-08-31 1996-06-18 David H. Gelfand Recombinant fungal cellulases
US5411873A (en) 1984-05-29 1995-05-02 Genencor, Inc. Process for producing heterologous polypeptides
ATE117020T1 (de) 1985-08-29 1995-01-15 Genencor Int Expression von heterologen polypeptiden in filamentösen pilzen, verfahren zu deren herstellung und vektoren zu deren herstellung.
US5364770A (en) * 1985-08-29 1994-11-15 Genencor International Inc. Heterologous polypeptides expressed in aspergillus
US5679543A (en) * 1985-08-29 1997-10-21 Genencor International, Inc. DNA sequences, vectors and fusion polypeptides to increase secretion of desired polypeptides from filamentous fungi
US4935349A (en) * 1986-01-17 1990-06-19 Zymogenetics, Inc. Expression of higher eucaryotic genes in aspergillus
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CA1333777C (en) * 1988-07-01 1995-01-03 Randy M. Berka Aspartic proteinase deficient filamentous fungi
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JP2002521652A (ja) * 1998-07-20 2002-07-16 ファーメクサ エイ/エス リガンドおよびターゲット生体分子を同定するための新規な方法
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Also Published As

Publication number Publication date
KR20120099303A (ko) 2012-09-07
CN1875029A (zh) 2006-12-06
KR101348530B1 (ko) 2014-02-14
EP1689766A1 (en) 2006-08-16
US7279564B2 (en) 2007-10-09
CA2545053C (en) 2016-04-19
CA2545053A1 (en) 2005-05-26
CN1875029B (zh) 2010-06-16
US20080234465A1 (en) 2008-09-25
WO2005047302A1 (en) 2005-05-26
EP2292641A3 (en) 2011-06-22
US20050153399A1 (en) 2005-07-14
US20080131932A1 (en) 2008-06-05
US7592420B2 (en) 2009-09-22
EP2292641B1 (en) 2017-12-06
CN101857867A (zh) 2010-10-13
DK1689766T3 (da) 2012-07-16
KR20110119844A (ko) 2011-11-02
ATE555119T1 (de) 2012-05-15
KR20060111451A (ko) 2006-10-27
JP2007528212A (ja) 2007-10-11
EP1689766B1 (en) 2012-04-25
JP4834554B2 (ja) 2011-12-14
EP1689766A4 (en) 2008-07-23
EP2292641A2 (en) 2011-03-09
US7592157B2 (en) 2009-09-22
KR101211444B1 (ko) 2012-12-13

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20221025