HK1091481A1 - Therapeutic agents useful for treating pain - Google Patents

Therapeutic agents useful for treating pain

Info

Publication number
HK1091481A1
HK1091481A1 HK06111966A HK06111966A HK1091481A1 HK 1091481 A1 HK1091481 A1 HK 1091481A1 HK 06111966 A HK06111966 A HK 06111966A HK 06111966 A HK06111966 A HK 06111966A HK 1091481 A1 HK1091481 A1 HK 1091481A1
Authority
HK
Hong Kong
Prior art keywords
therapeutic agents
agents useful
treating pain
compound
animal
Prior art date
Application number
HK06111966A
Other languages
English (en)
Inventor
Qun Sun
Original Assignee
Euro Celtique Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro Celtique Sa filed Critical Euro Celtique Sa
Publication of HK1091481A1 publication Critical patent/HK1091481A1/xx

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79Acids; Esters
    • C07D213/80Acids; Esters in position 3
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    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Rheumatology (AREA)
  • Reproductive Health (AREA)
  • Virology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Psychology (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
HK06111966A 2003-09-22 2006-10-31 Therapeutic agents useful for treating pain HK1091481A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50473003P 2003-09-22 2003-09-22
PCT/US2004/030825 WO2005030753A2 (fr) 2003-09-22 2004-09-21 Agents therapeutiques utiles pour traiter la douleur

Publications (1)

Publication Number Publication Date
HK1091481A1 true HK1091481A1 (en) 2007-01-19

Family

ID=34392938

Family Applications (1)

Application Number Title Priority Date Filing Date
HK06111966A HK1091481A1 (en) 2003-09-22 2006-10-31 Therapeutic agents useful for treating pain

Country Status (17)

Country Link
US (3) US7772254B2 (fr)
EP (1) EP1664016B9 (fr)
JP (1) JP4630871B2 (fr)
CN (1) CN1863790A (fr)
AT (1) ATE412646T1 (fr)
AU (1) AU2004276252B2 (fr)
CA (1) CA2537004A1 (fr)
CY (1) CY1109242T1 (fr)
DE (1) DE602004017481D1 (fr)
DK (1) DK1664016T3 (fr)
ES (1) ES2317052T3 (fr)
HK (1) HK1091481A1 (fr)
MX (1) MXPA06003123A (fr)
PL (1) PL1664016T3 (fr)
PT (1) PT1664016E (fr)
SI (1) SI1664016T1 (fr)
WO (1) WO2005030753A2 (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE452637T1 (de) 2001-01-29 2010-01-15 Shionogi & Co Arzneipräparat, das als wirkstoff 5-methyl-1- phenyl-2-(1h)-pyridon enthält
US7582635B2 (en) 2002-12-24 2009-09-01 Purdue Pharma, L.P. Therapeutic agents useful for treating pain
EP1664041B1 (fr) * 2003-09-22 2008-07-02 Euro-Celtique S.A. Composes phenyl-carboxamide utiles pour traiter la douleur
WO2005073193A1 (fr) * 2004-01-23 2005-08-11 Amgen Inc. Ligands du recepteur vanilloide et leur utilisation dans des traitements
JP2009519208A (ja) * 2005-12-15 2009-05-14 塩野義製薬株式会社 アミド誘導体を含有する医薬組成物
US20080051380A1 (en) 2006-08-25 2008-02-28 Auerbach Alan H Methods and compositions for treating cancer
CN101679304A (zh) * 2007-04-13 2010-03-24 诺瓦提斯公司 作为gpbar1激动剂的哒嗪-、吡啶-和吡喃-衍生物
CA2684105C (fr) 2007-05-03 2011-09-06 Pfizer Limited Derives de la pyridine
AU2008255048B2 (en) * 2007-05-15 2014-05-01 Barry M. Fell Surgically implantable knee prosthesis with captured keel
US8759362B2 (en) * 2008-10-24 2014-06-24 Purdue Pharma L.P. Bicycloheteroaryl compounds and their use as TRPV1 ligands
US8703962B2 (en) * 2008-10-24 2014-04-22 Purdue Pharma L.P. Monocyclic compounds and their use as TRPV1 ligands
CN102030771B (zh) * 2009-09-30 2013-07-17 孙群 作为trpv1阻断剂的化合物、药物组合物及其医药用途
US8921373B2 (en) 2010-06-22 2014-12-30 Shionogi & Co., Ltd. Compounds having TRPV1 antagonistic activity and uses thereof
EP2709609B1 (fr) 2011-05-17 2017-10-04 Shionogi & Co., Ltd. Composés hétérocycliques
MY185061A (en) 2011-06-22 2021-04-30 Shionogi & Co Trpv1 antagonists including dihydroxy substituent and uses thereof
US9394293B2 (en) 2011-08-10 2016-07-19 Purdue Pharma L.P. TRPV1 antagonists including dihydroxy substituent and uses thereof
TWI572597B (zh) 2012-06-29 2017-03-01 美國禮來大藥廠 二甲基-苯甲酸化合物
WO2014121033A1 (fr) 2013-02-04 2014-08-07 Fl Therapeutics Llc Complexes solubles d'analogues de médicament et d'albumine
ES2729642T3 (es) * 2013-09-24 2019-11-05 Purdue Pharma Lp Tratamiento del dolor por quemaduras mediante moduladores de TRPV1
RS58594B1 (sr) 2013-12-17 2019-05-31 Lilly Co Eli Jedinjenja dimetilbenzoeve kiseline
US9937259B2 (en) 2014-06-27 2018-04-10 Zhuhai Beihai Biotech Co., Ltd. Abiraterone derivatives and non-covalent complexes with albumin
WO2016065139A1 (fr) 2014-10-24 2016-04-28 Fl Therapeutics Llc Pipéridine-2, 6-diones 3-substitués et complexes non-covalents avec l'albumine
CA2937365C (fr) 2016-03-29 2018-09-18 F. Hoffmann-La Roche Ag Formulation en granules de 5-methyl-1-phenyl-2-(1h)-pyridone et methode de fabrication associee
KR20240115925A (ko) 2016-07-29 2024-07-26 얀센 파마슈티카 엔브이 전립선암의 치료 방법
GB201709459D0 (en) * 2017-06-14 2017-07-26 Intrabio Ltd Treatment for migraine
DE102022104759A1 (de) 2022-02-28 2023-08-31 SCi Kontor GmbH Co-Kristall-Screening Verfahren, insbesondere zur Herstellung von Co-Kristallen

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3536809A (en) * 1969-02-17 1970-10-27 Alza Corp Medication method
US3598123A (en) * 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US3845770A (en) * 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
US3916899A (en) * 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
US4008719A (en) * 1976-02-02 1977-02-22 Alza Corporation Osmotic system having laminar arrangement for programming delivery of active agent
IE58110B1 (en) * 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
US5316759A (en) * 1986-03-17 1994-05-31 Robert J. Schaap Agonist-antagonist combination to reduce the use of nicotine and other drugs
US5198459A (en) * 1987-07-11 1993-03-30 Sandoz Ltd. Use of 5HT-3 antagonists in preventing or reducing dependency on dependency-inducing agents
DE3822792C2 (de) * 1987-07-11 1997-11-27 Sandoz Ag Neue Verwendung von 5HT¶3¶-Antagonisten
US5073543A (en) * 1988-07-21 1991-12-17 G. D. Searle & Co. Controlled release formulations of trophic factors in ganglioside-lipsome vehicle
IT1229203B (it) * 1989-03-22 1991-07-25 Bioresearch Spa Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative.
US5120548A (en) * 1989-11-07 1992-06-09 Merck & Co., Inc. Swelling modulated polymeric drug delivery device
US5075341A (en) * 1989-12-01 1991-12-24 The Mclean Hospital Corporation Treatment for cocaine abuse
US5733566A (en) * 1990-05-15 1998-03-31 Alkermes Controlled Therapeutics Inc. Ii Controlled release of antiparasitic agents in animals
US5698155A (en) * 1991-05-31 1997-12-16 Gs Technologies, Inc. Method for the manufacture of pharmaceutical cellulose capsules
GB9119932D0 (en) * 1991-09-18 1991-10-30 Glaxo Group Ltd Chemical compounds
US6204284B1 (en) * 1991-12-20 2001-03-20 American Cyanamid Company Use of 1-(substitutedphenyl)-3-azabicyclo[3.1.0]hexanes for the treatment of chemical dependencies
US5580578A (en) * 1992-01-27 1996-12-03 Euro-Celtique, S.A. Controlled release formulations coated with aqueous dispersions of acrylic polymers
US5232934A (en) * 1992-07-17 1993-08-03 Warner-Lambert Co. Method for the treatment of psychomotor stimulant addiction
EP0659047A1 (fr) 1992-09-09 1995-06-28 E.I. Du Pont De Nemours And Company Composes de benzene herbicides
DE4234295A1 (de) * 1992-10-12 1994-04-14 Thomae Gmbh Dr K Carbonsäurederivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
US5591767A (en) * 1993-01-25 1997-01-07 Pharmetrix Corporation Liquid reservoir transdermal patch for the administration of ketorolac
US5321012A (en) * 1993-01-28 1994-06-14 Virginia Commonwealth University Medical College Inhibiting the development of tolerance to and/or dependence on a narcotic addictive substance
GB2276162A (en) * 1993-03-17 1994-09-21 Glaxo Group Ltd Aniline and benazilide derivatives
GB2276163A (en) * 1993-03-17 1994-09-21 Glaxo Group Ltd Pyridine compounds.
IT1270594B (it) * 1994-07-07 1997-05-07 Recordati Chem Pharm Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida
US5556837A (en) * 1994-08-01 1996-09-17 Regeneron Pharmaceuticals Inc. Methods for treating addictive disorders
US5762925A (en) * 1994-11-03 1998-06-09 Sagen; Jacqueline Preventing opiate tolerance by cellular implantation
EP0833622B8 (fr) * 1995-06-12 2005-10-12 G.D. Searle & Co. Compositions comprenant un inhibiteur de cyclooxygenase-2 et un inhibiteur de 5-lipoxygenase
ATE253111T1 (de) * 1997-08-20 2003-11-15 Univ California Für den capsaicin rezeptor kodierende nukleinsäuresequenzen und dem capsaicin rezeptor ähnliche polypeptide und ihre verwendung
EP0943683A1 (fr) * 1998-03-10 1999-09-22 Smithkline Beecham Plc Homologue humain du récepteur vanilloide Vanilrep1
WO2000039117A1 (fr) 1998-12-23 2000-07-06 Eli Lilly And Company AMIDES HETEROAROMATIQUES COMME INHIBITEURS DU FACTEUR Xa
GB9907097D0 (en) * 1999-03-26 1999-05-19 Novartis Ag Organic compounds
US6495550B2 (en) * 1999-08-04 2002-12-17 Icagen, Inc. Pyridine-substituted benzanilides as potassium ion channel openers
ES2316777T3 (es) * 2002-02-15 2009-04-16 Glaxo Group Limited Moduladores de receptores vainilloides.
GB0209715D0 (en) * 2002-04-27 2002-06-05 Astrazeneca Ab Chemical compounds
CA2494102A1 (fr) * 2002-07-30 2004-02-05 Banyu Pharmaceutical Co., Ltd. Antagoniste de recepteur d'hormone concentrant de la melanine comprenant un derive de benzimidazole en tant qu'ingredient actif
US20040110802A1 (en) * 2002-08-23 2004-06-10 Atli Thorarensen Antibacterial benzoic acid derivatives
CA2510471A1 (fr) * 2002-12-19 2004-07-08 Neurogen Corporation Analogues d'arylamide d'acide biphenyl-4-carboxylique substitues
AU2003301226A1 (en) 2002-12-20 2004-07-22 Pharmacia Corp Acyclic pyrazole compounds for the inhibition of mitogen activated protein kinase-activated protein kinase-2
ATE450533T1 (de) 2003-02-14 2009-12-15 Glaxo Group Ltd Carboxamidderivate
WO2004080411A2 (fr) * 2003-03-07 2004-09-23 Neurocrine Biosciences, Inc. Antagonistes du recepteur de l'hormone concentrant la melanine et compositions et methodes associees
EP1653934B1 (fr) 2003-08-15 2008-05-14 AB Science Utilisation d'inhibiteurs de c-kit pour le traitement du diabete de type ii
EP1664041B1 (fr) * 2003-09-22 2008-07-02 Euro-Celtique S.A. Composes phenyl-carboxamide utiles pour traiter la douleur

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JP4630871B2 (ja) 2011-02-09
US20110288100A1 (en) 2011-11-24
CA2537004A1 (fr) 2005-04-07
WO2005030753A2 (fr) 2005-04-07
US20100317670A1 (en) 2010-12-16
US7772254B2 (en) 2010-08-10
AU2004276252A1 (en) 2005-04-07
EP1664016B9 (fr) 2009-07-08
WO2005030753A3 (fr) 2005-05-06
ES2317052T3 (es) 2009-04-16
CN1863790A (zh) 2006-11-15
DK1664016T3 (da) 2009-02-23
EP1664016A2 (fr) 2006-06-07
EP1664016B1 (fr) 2008-10-29
US20060241117A1 (en) 2006-10-26
CY1109242T1 (el) 2014-07-02
SI1664016T1 (sl) 2009-04-30
US7994177B2 (en) 2011-08-09
ATE412646T1 (de) 2008-11-15
AU2004276252B2 (en) 2007-11-22
DE602004017481D1 (de) 2008-12-11
PL1664016T3 (pl) 2009-04-30

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