HK1090354A1 - Novel dibenzo [b,f]oxepine-10-carboxamides and pharmaceutical uses thereof - Google Patents
Novel dibenzo [b,f]oxepine-10-carboxamides and pharmaceutical uses thereofInfo
- Publication number
- HK1090354A1 HK1090354A1 HK06111074.0A HK06111074A HK1090354A1 HK 1090354 A1 HK1090354 A1 HK 1090354A1 HK 06111074 A HK06111074 A HK 06111074A HK 1090354 A1 HK1090354 A1 HK 1090354A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- oxepine
- carboxamides
- pharmaceutical uses
- novel dibenzo
- dibenzo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/82—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D313/14—[b,f]-condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/30—Ortho- or ortho- and peri-condensed systems containing three rings containing seven-membered rings
- C07C2603/32—Dibenzocycloheptenes; Hydrogenated dibenzocycloheptenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Oncology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0317491.9A GB0317491D0 (en) | 2003-07-25 | 2003-07-25 | Organic compounds |
| PCT/EP2004/008283 WO2005014517A2 (en) | 2003-07-25 | 2004-07-23 | Novel dibenzo[b,f]oxepine-10-carboxamides and pharmaceutical uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1090354A1 true HK1090354A1 (en) | 2006-12-22 |
Family
ID=27772721
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK06111074.0A HK1090354A1 (en) | 2003-07-25 | 2006-10-09 | Novel dibenzo [b,f]oxepine-10-carboxamides and pharmaceutical uses thereof |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US7612054B2 (pt) |
| EP (1) | EP1651592B1 (pt) |
| JP (1) | JP2006528610A (pt) |
| CN (1) | CN100513387C (pt) |
| AT (1) | ATE430126T1 (pt) |
| AU (1) | AU2004263286B2 (pt) |
| BR (1) | BRPI0412928A (pt) |
| CA (1) | CA2533174A1 (pt) |
| DE (1) | DE602004020896D1 (pt) |
| ES (1) | ES2324615T3 (pt) |
| GB (1) | GB0317491D0 (pt) |
| HK (1) | HK1090354A1 (pt) |
| MX (1) | MXPA06000914A (pt) |
| PL (1) | PL1651592T3 (pt) |
| PT (1) | PT1651592E (pt) |
| WO (1) | WO2005014517A2 (pt) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003293155A1 (en) * | 2002-11-27 | 2004-06-23 | Elan Pharmaceutical, Inc. | Substituted ureas and carbamates |
| WO2005087751A2 (en) | 2004-03-09 | 2005-09-22 | Elan Pharmaceuticals, Inc. | Substituted hydroxyethylamine aspartyl protease inhibitors |
| JP2007528403A (ja) * | 2004-03-09 | 2007-10-11 | エラン ファーマシューティカルズ，インコーポレイテッド | 二環式アスパラギン酸プロテアーゼ阻害薬を用いるアミロイドーシスの処置方法 |
| US7385085B2 (en) | 2004-07-09 | 2008-06-10 | Elan Pharmaceuticals, Inc. | Oxime derivative substituted hydroxyethylamine aspartyl protease inhibitors |
| AU2005265354A1 (en) * | 2004-07-09 | 2006-01-26 | Elan Pharmaceuticals, Inc. | Oxime derivative hydroxyethylamine aspartyl-protease inhibitors |
| WO2007047305A1 (en) | 2005-10-12 | 2007-04-26 | Elan Pharmaceuticals, Inc. | Methods of treating amyloidosis using cyclopropyl derivative aspartyl protease inhibitors |
| WO2007061670A1 (en) * | 2005-11-21 | 2007-05-31 | Amgen Inc. | Beta-secretase modulators and methods of use |
| AU2008275735B2 (en) * | 2007-07-05 | 2014-03-27 | Merck Sharp & Dohme Corp. | Tetrahydropyranochromene gamma secretase inhibitors |
-
2003
- 2003-07-25 GB GBGB0317491.9A patent/GB0317491D0/en not_active Ceased
-
2004
- 2004-07-23 PT PT04763454T patent/PT1651592E/pt unknown
- 2004-07-23 EP EP04763454A patent/EP1651592B1/en not_active Not-in-force
- 2004-07-23 CA CA002533174A patent/CA2533174A1/en not_active Abandoned
- 2004-07-23 MX MXPA06000914A patent/MXPA06000914A/es not_active Application Discontinuation
- 2004-07-23 AU AU2004263286A patent/AU2004263286B2/en not_active Ceased
- 2004-07-23 ES ES04763454T patent/ES2324615T3/es active Active
- 2004-07-23 AT AT04763454T patent/ATE430126T1/de not_active IP Right Cessation
- 2004-07-23 CN CNB2004800203477A patent/CN100513387C/zh not_active Expired - Fee Related
- 2004-07-23 JP JP2006520808A patent/JP2006528610A/ja active Pending
- 2004-07-23 PL PL04763454T patent/PL1651592T3/pl unknown
- 2004-07-23 BR BRPI0412928-8A patent/BRPI0412928A/pt not_active IP Right Cessation
- 2004-07-23 DE DE602004020896T patent/DE602004020896D1/de active Active
- 2004-07-23 WO PCT/EP2004/008283 patent/WO2005014517A2/en active Application Filing
- 2004-07-23 US US10/565,456 patent/US7612054B2/en not_active Expired - Fee Related
-
2006
- 2006-10-09 HK HK06111074.0A patent/HK1090354A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2006528610A (ja) | 2006-12-21 |
| DE602004020896D1 (de) | 2009-06-10 |
| CA2533174A1 (en) | 2005-02-17 |
| CN1823036A (zh) | 2006-08-23 |
| EP1651592A2 (en) | 2006-05-03 |
| ES2324615T3 (es) | 2009-08-11 |
| MXPA06000914A (es) | 2006-03-30 |
| WO2005014517A3 (en) | 2005-04-28 |
| WO2005014517A2 (en) | 2005-02-17 |
| US7612054B2 (en) | 2009-11-03 |
| BRPI0412928A (pt) | 2006-09-26 |
| PL1651592T3 (pl) | 2009-10-30 |
| AU2004263286B2 (en) | 2009-01-15 |
| AU2004263286A1 (en) | 2005-02-17 |
| GB0317491D0 (en) | 2003-08-27 |
| ATE430126T1 (de) | 2009-05-15 |
| EP1651592B1 (en) | 2009-04-29 |
| US20070111991A1 (en) | 2007-05-17 |
| PT1651592E (pt) | 2009-07-23 |
| CN100513387C (zh) | 2009-07-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20130723 |