HK1086493A1 - Treatment of proliferative diseases with epothilone derivatives and radiation - Google Patents

Treatment of proliferative diseases with epothilone derivatives and radiation

Info

Publication number
HK1086493A1
HK1086493A1 HK06106603.0A HK06106603A HK1086493A1 HK 1086493 A1 HK1086493 A1 HK 1086493A1 HK 06106603 A HK06106603 A HK 06106603A HK 1086493 A1 HK1086493 A1 HK 1086493A1
Authority
HK
Hong Kong
Prior art keywords
treatment
radiation
proliferative diseases
epothilone derivatives
epothilone
Prior art date
Application number
HK06106603.0A
Other languages
English (en)
Inventor
Martin Pruschy
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of HK1086493A1 publication Critical patent/HK1086493A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Radiation-Therapy Devices (AREA)
HK06106603.0A 2003-03-14 2006-06-08 Treatment of proliferative diseases with epothilone derivatives and radiation HK1086493A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0305928.4A GB0305928D0 (en) 2003-03-14 2003-03-14 Organic compounds
PCT/EP2004/002610 WO2004080458A1 (en) 2003-03-14 2004-03-12 Treatment of proliferative diseases with epothilone derivatives and radiation

Publications (1)

Publication Number Publication Date
HK1086493A1 true HK1086493A1 (en) 2006-09-22

Family

ID=9954825

Family Applications (1)

Application Number Title Priority Date Filing Date
HK06106603.0A HK1086493A1 (en) 2003-03-14 2006-06-08 Treatment of proliferative diseases with epothilone derivatives and radiation

Country Status (26)

Country Link
US (2) US20070129411A1 (ja)
EP (1) EP1605937B1 (ja)
JP (1) JP4927530B2 (ja)
KR (1) KR20050109988A (ja)
CN (2) CN1758908A (ja)
AT (1) ATE491450T1 (ja)
AU (1) AU2004218927A1 (ja)
BR (1) BRPI0408366A (ja)
CA (1) CA2519037A1 (ja)
DE (1) DE602004030545D1 (ja)
ES (1) ES2358109T3 (ja)
GB (1) GB0305928D0 (ja)
HK (1) HK1086493A1 (ja)
IL (1) IL170632A (ja)
IS (1) IS8059A (ja)
MA (1) MA27634A1 (ja)
MX (1) MXPA05009808A (ja)
NO (1) NO20054723L (ja)
NZ (1) NZ542305A (ja)
PL (1) PL1605937T3 (ja)
PT (1) PT1605937E (ja)
RU (1) RU2381799C2 (ja)
TN (1) TNSN05226A1 (ja)
TW (1) TWI358295B (ja)
WO (1) WO2004080458A1 (ja)
ZA (1) ZA200506942B (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2281692T3 (es) 2002-08-23 2007-10-01 Sloan-Kettering Institute For Cancer Research Sintesis de epotilones, sus intermediarios, sus analogos y sus usos.
US7649006B2 (en) 2002-08-23 2010-01-19 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto and analogues thereof
EP1640004A1 (en) * 2004-09-24 2006-03-29 Schering Aktiengesellschaft Use of epothilones in the treatment of bone metastases and bone tumors or cancers
US20060121511A1 (en) 2004-11-30 2006-06-08 Hyerim Lee Biomarkers and methods for determining sensitivity to microtubule-stabilizing agents
EP3566719A1 (en) 2010-05-18 2019-11-13 Cerulean Pharma Inc. Compositions and methods for treatment of autoimmune and other diseases

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6441025B2 (en) * 1996-03-12 2002-08-27 Pg-Txl Company, L.P. Water soluble paclitaxel derivatives
DE69734362T2 (de) * 1996-12-03 2006-07-20 Sloan-Kettering Institute For Cancer Research Synthese von epothilonen, zwischenprodukte dazu, analoga und verwendungen davon
US6605599B1 (en) * 1997-07-08 2003-08-12 Bristol-Myers Squibb Company Epothilone derivatives
JP2001288097A (ja) * 2000-04-07 2001-10-16 Pg-Txl Co Lp 水溶性パクリタキセル誘導体
MXPA03006412A (es) * 2001-01-25 2003-10-15 Bristol Myers Squibb Co Metodos para administrar analogos de epotilona para tratamiento de cancer.
CA2440555A1 (en) * 2001-03-14 2002-09-19 Bristol-Myers Squibb Company Combination of epothilone analogs and chemotherapeutic agents for the treatment of proliferative diseases

Also Published As

Publication number Publication date
NO20054723L (no) 2005-10-13
JP2006520353A (ja) 2006-09-07
TNSN05226A1 (en) 2007-06-11
MA27634A1 (fr) 2005-11-01
DE602004030545D1 (de) 2011-01-27
MXPA05009808A (es) 2005-10-26
BRPI0408366A (pt) 2006-03-21
RU2381799C2 (ru) 2010-02-20
CN1758908A (zh) 2006-04-12
TWI358295B (en) 2012-02-21
ATE491450T1 (de) 2011-01-15
WO2004080458A1 (en) 2004-09-23
AU2004218927A1 (en) 2004-09-23
TW200505444A (en) 2005-02-16
CA2519037A1 (en) 2004-03-23
ZA200506942B (en) 2006-07-26
NZ542305A (en) 2009-03-31
RU2005131723A (ru) 2007-08-20
EP1605937A1 (en) 2005-12-21
PL1605937T3 (pl) 2011-05-31
IS8059A (is) 2005-10-04
US20120053559A1 (en) 2012-03-01
GB0305928D0 (en) 2003-04-23
KR20050109988A (ko) 2005-11-22
IL170632A (en) 2012-01-31
JP4927530B2 (ja) 2012-05-09
PT1605937E (pt) 2011-03-17
ES2358109T3 (es) 2011-05-05
US20070129411A1 (en) 2007-06-07
CN101804050A (zh) 2010-08-18
EP1605937B1 (en) 2010-12-15

Similar Documents

Publication Publication Date Title
IL260127B (en) mek inhibitors and methods of using them
BR0312573A (pt) Derivados de fenil-[4-(3-fenil-1h-pirazol-4-il)-pirimidin-2-il]-amina
IL174210A0 (en) 1,4 disubstituted isoquinilone derivatives as raf-kinase inhibitors useful for the treatment of proliferative diseases
TNSN07093A1 (en) Bicyclic amides as kinase inhibitors
TW200600087A (en) Methods and compositions for treating amyloid-related diseases
TW200608979A (en) Pyrrolotriazine derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis
NO20055894L (no) Fremgangsmater og blandinger for behandling av amyloidrelatertere sykdommer
MX2009006704A (es) Derivados de amina triciclicos como inhibidores de proteina de tirosina cinasa.
WO2003080582A3 (de) Fredericamycin-derivate
TW200724537A (en) Pyrimidine derivatives for treatment of hyperproliferative disorders
IL178261A0 (en) Use of 5,10-methylene tetrahydrofolate for the treatment of cancer
WO2007016338A3 (en) Use of chk2 kinase inhibitors for cancer treatment
TW200740812A (en) 1,4-Dihydropyridine-fused heterocycles, process for preparing the same, use and compositions containing them
TW200631606A (en) Organic compounds
HK1086493A1 (en) Treatment of proliferative diseases with epothilone derivatives and radiation
WO2007050655A3 (en) Combination of histone deacetylase inhibitors and radiation
TW200510348A (en) 5-aryltetrazole compounds, compositions thereof, and uses therefor
SI1663244T1 (sl) Pteridinski derivati za zdravljenje bolezni, povezanih s TNF-alfa
UA96742C2 (en) Mek inhibitors and use thereof
ZA200605653B (en) Proline derivatives used as pharmaceutical active ingredients for the treatment of tumours
UA87851C2 (ru) Производные пирролотриазина, применимые для лечения гиперпролиферативных нарушений и заболеваний, связанных с ангиогенезом

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20150312