HK1084398A1 - Synthesis of quinoline 5-carboxamides useful for the preparation of pde iv inhibitors - Google Patents
Synthesis of quinoline 5-carboxamides useful for the preparation of pde iv inhibitorsInfo
- Publication number
- HK1084398A1 HK1084398A1 HK06106732A HK06106732A HK1084398A1 HK 1084398 A1 HK1084398 A1 HK 1084398A1 HK 06106732 A HK06106732 A HK 06106732A HK 06106732 A HK06106732 A HK 06106732A HK 1084398 A1 HK1084398 A1 HK 1084398A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- pde
- quinoline
- inhibitors
- synthesis
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
- C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
- C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
- C04B35/622—Forming processes; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
- C04B35/626—Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B
- C04B35/63—Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B using additives specially adapted for forming the products, e.g.. binder binders
- C04B35/632—Organic additives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
- C07C229/54—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C229/64—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring the carbon skeleton being further substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Ceramic Engineering (AREA)
- Manufacturing & Machinery (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Structural Engineering (AREA)
- Pain & Pain Management (AREA)
- Materials Engineering (AREA)
- Inorganic Chemistry (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US50310803P | 2003-09-15 | 2003-09-15 | |
PCT/US2004/029773 WO2005028471A1 (en) | 2003-09-15 | 2004-09-13 | Synthesis of quinoline 5-carboxamides useful for the preparation of pde iv inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1084398A1 true HK1084398A1 (en) | 2006-07-28 |
Family
ID=34375311
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK06106732A HK1084398A1 (en) | 2003-09-15 | 2006-06-13 | Synthesis of quinoline 5-carboxamides useful for the preparation of pde iv inhibitors |
Country Status (12)
Country | Link |
---|---|
US (1) | US7129357B2 (de) |
EP (1) | EP1664024B1 (de) |
JP (1) | JP2007505834A (de) |
CN (1) | CN1878765A (de) |
AT (1) | ATE366728T1 (de) |
CA (1) | CA2538591A1 (de) |
DE (1) | DE602004007531T2 (de) |
ES (1) | ES2286685T3 (de) |
HK (1) | HK1084398A1 (de) |
MX (1) | MXPA06002917A (de) |
WO (1) | WO2005028471A1 (de) |
ZA (1) | ZA200602155B (de) |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL126557A (en) * | 1996-05-20 | 2002-09-12 | Darwin Discovery Ltd | Quinoline (thio) carboxamides inhibiting TNF or PDE-IV and pharmaceutical preparations containing them |
US6262070B1 (en) * | 1998-11-04 | 2001-07-17 | Darwin Discovery Ltd. | Heterocyclic compounds and their therapeutic use |
GB9824160D0 (en) * | 1998-11-04 | 1998-12-30 | Darwin Discovery Ltd | Heterocyclic compounds and their therapeutic use |
US6211243B1 (en) * | 1999-09-22 | 2001-04-03 | B. Ron Johnson | Methods for treating cold sores with anti-infective compositions |
-
2004
- 2004-09-13 JP JP2006526359A patent/JP2007505834A/ja active Pending
- 2004-09-13 DE DE602004007531T patent/DE602004007531T2/de not_active Expired - Fee Related
- 2004-09-13 CN CNA2004800333343A patent/CN1878765A/zh active Pending
- 2004-09-13 ES ES04788707T patent/ES2286685T3/es active Active
- 2004-09-13 MX MXPA06002917A patent/MXPA06002917A/es active IP Right Grant
- 2004-09-13 WO PCT/US2004/029773 patent/WO2005028471A1/en active IP Right Grant
- 2004-09-13 EP EP04788707A patent/EP1664024B1/de active Active
- 2004-09-13 CA CA002538591A patent/CA2538591A1/en not_active Abandoned
- 2004-09-13 AT AT04788707T patent/ATE366728T1/de not_active IP Right Cessation
- 2004-09-13 US US10/939,740 patent/US7129357B2/en not_active Expired - Fee Related
-
2006
- 2006-03-14 ZA ZA200602155A patent/ZA200602155B/en unknown
- 2006-06-13 HK HK06106732A patent/HK1084398A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ATE366728T1 (de) | 2007-08-15 |
EP1664024A1 (de) | 2006-06-07 |
ZA200602155B (en) | 2007-09-26 |
US20050124655A1 (en) | 2005-06-09 |
CA2538591A1 (en) | 2005-03-31 |
ES2286685T3 (es) | 2007-12-01 |
DE602004007531D1 (de) | 2007-08-23 |
DE602004007531T2 (de) | 2008-03-13 |
MXPA06002917A (es) | 2006-05-31 |
CN1878765A (zh) | 2006-12-13 |
WO2005028471A1 (en) | 2005-03-31 |
EP1664024B1 (de) | 2007-07-11 |
JP2007505834A (ja) | 2007-03-15 |
US7129357B2 (en) | 2006-10-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20100913 |