HK1080402A1 - Minimally compliant, volume efficient piston for osmotic drug delivery systems - Google Patents

Minimally compliant, volume efficient piston for osmotic drug delivery systems

Info

Publication number
HK1080402A1
HK1080402A1 HK06100435A HK06100435A HK1080402A1 HK 1080402 A1 HK1080402 A1 HK 1080402A1 HK 06100435 A HK06100435 A HK 06100435A HK 06100435 A HK06100435 A HK 06100435A HK 1080402 A1 HK1080402 A1 HK 1080402A1
Authority
HK
Hong Kong
Prior art keywords
capsule
piston
agent
osmotic
drug delivery
Prior art date
Application number
HK06100435A
Other languages
English (en)
Inventor
Lautenbach Scott
Original Assignee
Intarcia Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intarcia Therapeutics Inc filed Critical Intarcia Therapeutics Inc
Publication of HK1080402A1 publication Critical patent/HK1080402A1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/145Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M2005/14513Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons with secondary fluid driving or regulating the infusion

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK06100435A 2002-06-26 2006-01-11 Minimally compliant, volume efficient piston for osmotic drug delivery systems HK1080402A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39200402P 2002-06-26 2002-06-26
PCT/US2003/020130 WO2004002565A1 (en) 2002-06-26 2003-06-25 Minimally compliant, volume efficient piston for osmotic drug delivery systems

Publications (1)

Publication Number Publication Date
HK1080402A1 true HK1080402A1 (en) 2006-04-28

Family

ID=30000792

Family Applications (1)

Application Number Title Priority Date Filing Date
HK06100435A HK1080402A1 (en) 2002-06-26 2006-01-11 Minimally compliant, volume efficient piston for osmotic drug delivery systems

Country Status (20)

Country Link
US (3) US6939556B2 (no)
EP (1) EP1551493B1 (no)
JP (1) JP4485945B2 (no)
KR (1) KR101046903B1 (no)
CN (1) CN100453130C (no)
AT (1) ATE376854T1 (no)
AU (1) AU2003256308B2 (no)
BR (1) BR0312429A (no)
CA (1) CA2490544C (no)
DE (1) DE60317225T2 (no)
EC (1) ECSP055578A (no)
ES (1) ES2295642T3 (no)
HK (1) HK1080402A1 (no)
IL (1) IL165975A (no)
MX (1) MXPA05000224A (no)
NO (1) NO20050368L (no)
NZ (1) NZ537628A (no)
TW (1) TW200531709A (no)
WO (1) WO2004002565A1 (no)
ZA (1) ZA200500744B (no)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY125870A (en) * 1997-07-25 2006-08-30 Alza Corp Osmotic delivery system flow modulator apparatus and method
US7258869B1 (en) 1999-02-08 2007-08-21 Alza Corporation Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle
US7919109B2 (en) * 1999-02-08 2011-04-05 Intarcia Therapeutics, Inc. Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicles
BR0317421A (pt) * 2002-12-19 2005-11-08 Alza Corp Géis de fase única não-aquosa estável e formulações destes para liberação a partir de um dispositivo implantável
US7731947B2 (en) * 2003-11-17 2010-06-08 Intarcia Therapeutics, Inc. Composition and dosage form comprising an interferon particle formulation and suspending vehicle
MXPA05010605A (es) * 2003-03-31 2005-11-23 Alza Corp Bomba osmotica con medios para disipar la presion interna.
CN1767812A (zh) * 2003-03-31 2006-05-03 阿尔萨公司 渗透输送系统以及用于缩短渗透输送系统启动时间的方法
KR20060121890A (ko) * 2003-11-06 2006-11-29 알자 코포레이션 이식형 삼투 펌프와 함께 사용하기 위한 모듈식 흡수율감소기
US20050266087A1 (en) * 2004-05-25 2005-12-01 Gunjan Junnarkar Formulations having increased stability during transition from hydrophobic vehicle to hydrophilic medium
RU2404750C2 (ru) 2004-11-23 2010-11-27 Адамас Фармасьютикалс, Инк. Композиция, содержащая основу или покрытие для замедленного высвобождения и антагонист nmda рецептора, способ введения такого nmda антагониста субъекту
US7619007B2 (en) 2004-11-23 2009-11-17 Adamas Pharmaceuticals, Inc. Method and composition for administering an NMDA receptor antagonist to a subject
WO2006058236A2 (en) 2004-11-24 2006-06-01 Neuromolecular Pharmaceuticals, Inc. Composition comprising an nmda receptor antagonist and levodopa and use thereof for treating neurological disease
WO2006084141A2 (en) * 2005-02-03 2006-08-10 Intarcia Therapeutics, Inc Suspension formulation of interferon
WO2006083761A2 (en) * 2005-02-03 2006-08-10 Alza Corporation Solvent/polymer solutions as suspension vehicles
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
US7959938B2 (en) * 2005-03-15 2011-06-14 Intarcia Therapeutics, Inc. Polyoxaester suspending vehicles for use with implantable delivery systems
CA2604052C (en) * 2005-04-06 2014-07-08 Adamas Pharmaceuticals, Inc. Methods and compositions for the treatment of cns-related conditions
US20070208041A1 (en) * 2005-10-13 2007-09-06 Stamler Jonathan S Compositions for the treatment and prevention of heart disease and methods of using same
CN101453982B (zh) 2006-05-30 2011-05-04 精达制药公司 两件式内部通道渗透递送系统流动调节器
WO2008021133A2 (en) * 2006-08-09 2008-02-21 Intarcia Therapeutics, Inc. Osmotic delivery systems and piston assemblies
EP2157967B1 (en) 2007-04-23 2013-01-16 Intarcia Therapeutics, Inc Suspension formulations of insulinotropic peptides and uses thereof
US8105261B2 (en) * 2007-07-02 2012-01-31 Cardiac Pacemakers, Inc. Osmotic devices and methods for diuretic therapy
US8394644B2 (en) 2007-11-08 2013-03-12 Honeywell International Inc. Microfluidic osmotic pump
EP2240155B1 (en) 2008-02-13 2012-06-06 Intarcia Therapeutics, Inc Devices, formulations, and methods for delivery of multiple beneficial agents
CN106539756A (zh) * 2008-10-15 2017-03-29 精达制药公司 高浓缩药物颗粒、制剂、混悬剂及其应用
ES2401007T3 (es) * 2009-06-26 2013-04-16 Taris Biomedical, Inc. Dispositivos de administración de fármaco implantables y procedimientos de fabricación de los mismos
CN104323981B (zh) 2009-09-28 2019-03-12 精达制药公司 基本稳态药物递送的快速建立和/或终止
AU2010300475A1 (en) 2009-09-30 2012-05-03 The Regents Of The University Of California Cofactors and methods for use for individuals
MX365650B (es) 2009-12-02 2019-06-10 Adamas Pharmaceuticals Inc Composiciones de amantadina y metodos para su uso.
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
WO2013012760A1 (en) 2011-07-15 2013-01-24 Numeta Sciences, Inc. Compositions and methods for modulating metabolic pathways
US9198454B2 (en) 2012-03-08 2015-12-01 Nusirt Sciences, Inc. Compositions, methods, and kits for regulating energy metabolism
MX2015004636A (es) * 2012-10-12 2015-10-22 Lilly Co Eli Motores químicos y métodos para su uso, especialmente en la inyección de fluidos altamente viscosos.
CA2891335C (en) 2012-11-13 2021-05-04 Nusirt Sciences, Inc. Compositions and methods for increasing energy metabolism
AU2014207707B2 (en) 2013-01-15 2018-11-01 Nusirt Sciences, Inc. Treating pulmonary conditions
WO2014138214A1 (en) * 2013-03-05 2014-09-12 Taris Biomedical, Inc. Drug delivery devices and methods for controlled drug release through device orifice
CA2902879C (en) 2013-03-15 2023-09-26 Nusirt Sciences, Inc. Leucine and nicotinic acid reduces lipid levels
US10154971B2 (en) 2013-06-17 2018-12-18 Adamas Pharma, Llc Methods of administering amantadine
KR20160119863A (ko) 2014-02-27 2016-10-14 뉴서트 사이언시스, 인크. 간 지방증의 감소 또는 예방을 위한 조성물 및 방법
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
WO2016196851A2 (en) 2015-06-03 2016-12-08 Intarcia Therapeutics, Inc. Implant placement and removal systems
CA3003747A1 (en) 2015-11-05 2017-05-11 The General Hospital Corporation Intrathecal delivery of nucleic acid sequences encoding abcd1 for treatment of adrenomyeloneuropathy
JP6902033B2 (ja) 2015-12-30 2021-07-14 アダマス ファーマシューティカルズ, インコーポレイテッド 発作−関連障害の処置のための方法および組成物
MX2018014016A (es) 2016-05-16 2019-08-01 Intarcia Therapeutics Inc Polipéptidos selectivos del receptor de glucagón y métodos para utilizarlos.
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
US10406336B2 (en) 2016-08-03 2019-09-10 Neil S. Davey Adjustable rate drug delivery implantable device
JP2020500163A (ja) 2016-10-20 2020-01-09 ペプトロン インコーポレイテッド 中枢神経系に神経保護ポリペプチドを送達する方法
CN110225762A (zh) 2017-01-03 2019-09-10 因塔西亚制药公司 包括glp-1受体激动剂的连续施用和药物的共同施用的方法
US11925790B2 (en) 2017-02-17 2024-03-12 Eli Lilly And Company Processes and devices for delivery of fluid by chemical reaction
KR20190126335A (ko) 2017-03-08 2019-11-11 인타르시아 세라퓨틱스 인코포레이티드 약물 전달 장치로부터 메스꺼움 유발 화합물을 투여하기 위한 장치 및 방법
WO2018200885A1 (en) 2017-04-26 2018-11-01 Neurocentria, Inc. Magnesium compositions and methods of use
AU2018329639B2 (en) 2017-09-08 2020-10-29 Eli Lilly And Company System for controlling gas generation within a drug delivery device
USD933219S1 (en) 2018-07-13 2021-10-12 Intarcia Therapeutics, Inc. Implant removal tool and assembly
EP3840735A4 (en) * 2018-08-23 2022-06-15 Baywind Bioventures CAPSULE DEVICE FOR DELIVERING AN ACTIVE PRINCIPLE TO THE DIGESTIVE TRACT
CA3116023A1 (en) 2018-10-11 2020-04-16 Intarcia Therapeutics, Inc. Human amylin analog polypeptides and methods of use

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4753651A (en) 1982-08-30 1988-06-28 Alza Corporation Self-driven pump
US4765989A (en) * 1983-05-11 1988-08-23 Alza Corporation Osmotic device for administering certain drugs
US4558888A (en) * 1983-09-19 1985-12-17 Minnesota Mining And Manufacturing Company Strip of binding tape
US4874388A (en) 1987-06-25 1989-10-17 Alza Corporation Multi-layer delivery system
US5034229A (en) * 1988-12-13 1991-07-23 Alza Corporation Dispenser for increasing feed conversion of hog
US5728088A (en) * 1988-12-13 1998-03-17 Alza Corporation Osmotic system for delivery of fluid-sensitive somatotropins to bovine animals
US4969884A (en) * 1988-12-28 1990-11-13 Alza Corporation Osmotically driven syringe
US5234424A (en) * 1988-12-28 1993-08-10 Alza Corporation Osmotically driven syringe
US5133974A (en) * 1989-05-05 1992-07-28 Kv Pharmaceutical Company Extended release pharmaceutical formulations
US5030216A (en) * 1989-12-15 1991-07-09 Alza Corporation Osmotically driven syringe
US5324280A (en) * 1990-04-02 1994-06-28 Alza Corporation Osmotic dosage system for delivering a formulation comprising liquid carrier and drug
US5234692A (en) * 1990-07-11 1993-08-10 Alza Corporation Delivery device with a protective sleeve
US5180591A (en) * 1990-07-11 1993-01-19 Alza Corporation Delivery device with a protective sleeve
US5443459A (en) * 1991-01-30 1995-08-22 Alza Corporation Osmotic device for delayed delivery of agent
US5861166A (en) * 1991-03-12 1999-01-19 Alza Corporation Delivery device providing beneficial agent stability
CN2085662U (zh) * 1991-03-29 1991-10-02 毕勇 药物″渗透泵″的生产装置
US5137727A (en) 1991-06-12 1992-08-11 Alza Corporation Delivery device providing beneficial agent stability
EP0664118B1 (en) 1991-10-04 1999-08-25 Yoshitomi Pharmaceutical Industries, Ltd. Sustained-release tablet
PT100944B (pt) * 1991-10-10 2000-02-29 Alza Corp Dispositivo para o fornecimento osmotico de farmacos com paredes de materiais hidrofobicos
US5580578A (en) * 1992-01-27 1996-12-03 Euro-Celtique, S.A. Controlled release formulations coated with aqueous dispersions of acrylic polymers
US5308348A (en) * 1992-02-18 1994-05-03 Alza Corporation Delivery devices with pulsatile effect
US5209746A (en) * 1992-02-18 1993-05-11 Alza Corporation Osmotically driven delivery devices with pulsatile effect
US5456679A (en) * 1992-02-18 1995-10-10 Alza Corporation Delivery devices with pulsatile effect
US5221278A (en) 1992-03-12 1993-06-22 Alza Corporation Osmotically driven delivery device with expandable orifice for pulsatile delivery effect
US5260069A (en) * 1992-11-27 1993-11-09 Anda Sr Pharmaceuticals Inc. Pulsatile particles drug delivery system
US5540665A (en) * 1994-01-31 1996-07-30 Alza Corporation Gas driven dispensing device and gas generating engine therefor
US5458888A (en) * 1994-03-02 1995-10-17 Andrx Pharmaceuticals, Inc. Controlled release tablet formulation
US5690952A (en) * 1995-06-07 1997-11-25 Judy A. Magruder et al. Implantable system for delivery of fluid-sensitive agents to animals
US6261584B1 (en) * 1996-02-02 2001-07-17 Alza Corporation Sustained delivery of an active agent using an implantable system
US6395292B2 (en) * 1996-02-02 2002-05-28 Alza Corporation Sustained delivery of an active agent using an implantable system
US6132420A (en) * 1996-02-02 2000-10-17 Alza Corporation Osmotic delivery system and method for enhancing start-up and performance of osmotic delivery systems
US6156331A (en) * 1996-02-02 2000-12-05 Alza Corporation Sustained delivery of an active agent using an implantable system
ATE303792T1 (de) * 1996-02-02 2005-09-15 Alza Corp Implantierbares system mit verzögerter wirkstofffreisetzung
ZA981610B (en) * 1997-03-24 1999-08-26 Alza Corp Self adjustable exit port.
MY125870A (en) * 1997-07-25 2006-08-30 Alza Corp Osmotic delivery system flow modulator apparatus and method
MY125849A (en) * 1997-07-25 2006-08-30 Alza Corp Osmotic delivery system, osmotic delivery system semipermeable body assembly, and method for controlling delivery rate of beneficial agents from osmotic delivery systems
AU1828599A (en) 1997-12-29 1999-07-19 Alza Corporation Osmotic delivery system with membrane plug retention mechanism
CN1161101C (zh) * 1998-12-17 2004-08-11 阿尔扎有限公司 用多层包衣将填充液体的明胶胶囊转变成控制释放的系统
AU2002225870B2 (en) * 2000-11-03 2006-09-21 Intarcia Therapeutics, Inc. Method for short-term and long-term drug dosimetry

Also Published As

Publication number Publication date
JP2005530588A (ja) 2005-10-13
CN1671439A (zh) 2005-09-21
JP4485945B2 (ja) 2010-06-23
US20070088337A1 (en) 2007-04-19
WO2004002565A1 (en) 2004-01-08
ATE376854T1 (de) 2007-11-15
US6939556B2 (en) 2005-09-06
EP1551493B1 (en) 2007-10-31
CN100453130C (zh) 2009-01-21
TW200531709A (en) 2005-10-01
ES2295642T3 (es) 2008-04-16
EP1551493A1 (en) 2005-07-13
KR101046903B1 (ko) 2011-07-06
AU2003256308B2 (en) 2008-07-03
US7112335B2 (en) 2006-09-26
ZA200500744B (en) 2006-03-29
CA2490544C (en) 2011-04-19
IL165975A (en) 2009-07-20
DE60317225D1 (de) 2007-12-13
DE60317225T2 (de) 2008-05-29
ECSP055578A (es) 2005-04-18
US20060111693A1 (en) 2006-05-25
NZ537628A (en) 2005-12-23
KR20050026416A (ko) 2005-03-15
US20040019345A1 (en) 2004-01-29
IL165975A0 (en) 2006-01-15
AU2003256308A1 (en) 2004-01-19
MXPA05000224A (es) 2005-06-03
CA2490544A1 (en) 2004-01-08
NO20050368L (no) 2005-01-24
BR0312429A (pt) 2005-04-19

Similar Documents

Publication Publication Date Title
ZA200500744B (en) Minimally compliant, volume efficient piston for osmotic drug delivery systems
WO2000040218A3 (en) Osmotic delivery system having space efficient piston
HK1055680A1 (en) Valve for osmotic devices
AU1808797A (en) Cartridge-based drug delivery device
AU2003249601A1 (en) Fluid delivery device having an electrochemical pump with an anionic exchange membrane and associated method
AU2003217111A1 (en) Fluid transfer assembly
MX2008001043A (es) Contenedor.
EA200201272A1 (ru) Медицинское устройство
AU2001295350A1 (en) Implantable medical device for delivering a liquid
WO2003026557A3 (en) Method and device for the iontophoretic delivery of a drug
WO2002068013A3 (en) Multiple canopy
CA2536845A1 (en) Drug delivery device
NZ331186A (en) Osmotically driven sustained delivery drug delivery capsule
ATE551044T1 (de) Medizinischer mehrkammer-behälter
EP1633426A4 (en) PROVISION OF THERAPEUTIC AGENT
NZ544741A (en) Device for the dosed delivery of a fluid, such as an infuser, using CO2 produced from the mixing of an base and an acid
WO1998057695A8 (en) Drug delivery system
CA2492836A1 (en) Administration device comprising an osmotic drive
PL1771349T3 (pl) Aplikator do substancji płynnych do zastosowań medycznych i/lub kosmetycznych
CA2468788A1 (en) Reverse-micellar delivery system for controlled transportation and enhanced absorption of agents
GB0102386D0 (en) Method for filling needless injector capsules
AU2003250952A1 (en) Use of a disposable container, microfluidic device and method for processing molecules
AR036914A1 (es) Valvula para fluidos criogenicos, y aplicacion para el empleo de dicha valvula
EP0934754A3 (en) Needleless medical device for delivering of therapeutic agent
MXPA05000254A (es) Inyector a chorro y metodo para su fabricacion y operacion.

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20210624