HK1079980B - 硬瘤化學栓塞治療成分 - Google Patents
硬瘤化學栓塞治療成分Info
- Publication number
- HK1079980B HK1079980B HK05112166.8A HK05112166A HK1079980B HK 1079980 B HK1079980 B HK 1079980B HK 05112166 A HK05112166 A HK 05112166A HK 1079980 B HK1079980 B HK 1079980B
- Authority
- HK
- Hong Kong
- Prior art keywords
- chemoembolotherapy
- composition
- solid tumors
- polymer
- water
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/06—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/001—Use of materials characterised by their function or physical properties
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/001—Use of materials characterised by their function or physical properties
- A61L24/0015—Medicaments; Biocides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F2/00—Processes of polymerisation
- C08F2/12—Polymerisation in non-solvents
- C08F2/14—Organic medium
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
- C08F290/08—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated side groups
- C08F290/12—Polymers provided for in subclasses C08C or C08F
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/48—Isomerisation; Cyclisation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/23—Carbohydrates
- A61L2300/232—Monosaccharides, disaccharides, polysaccharides, lipopolysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/06—Flowable or injectable implant compositions
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F2810/00—Chemical modification of a polymer
- C08F2810/30—Chemical modification of a polymer leading to the formation or introduction of aliphatic or alicyclic unsaturated groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Surgery (AREA)
- Materials Engineering (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP03250868 | 2003-02-12 | ||
GB0305322A GB0305322D0 (en) | 2003-03-07 | 2003-03-07 | Chemoembolisation |
PCT/GB2004/000548 WO2004071495A1 (en) | 2003-02-12 | 2004-02-12 | Composition for chemoembolotherapy of solid tumors |
Publications (2)
Publication Number | Publication Date |
---|---|
HK1079980A1 HK1079980A1 (en) | 2006-04-21 |
HK1079980B true HK1079980B (zh) | 2008-11-14 |
Family
ID=32870779
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK05112166.8A HK1079980B (zh) | 2003-02-12 | 2005-12-30 | 硬瘤化學栓塞治療成分 |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP1592405B1 (zh) |
JP (2) | JP4895802B2 (zh) |
KR (1) | KR101157260B1 (zh) |
CN (4) | CN106267325B (zh) |
AT (1) | ATE396708T1 (zh) |
DE (1) | DE602004014101D1 (zh) |
ES (1) | ES2308149T3 (zh) |
HK (1) | HK1079980B (zh) |
WO (1) | WO2004071495A1 (zh) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1430505A (zh) | 2000-03-24 | 2003-07-16 | 生物领域医疗公司 | 用于主动栓塞术的微球体 |
WO2005087193A2 (en) * | 2004-03-11 | 2005-09-22 | Biocompatibles Uk Limited | Chemoembolisation involving an anthracycline compound |
ATE505185T1 (de) * | 2004-09-07 | 2011-04-15 | Biocompatibles Uk Ltd | Arzneimittelabgabe aus embolischen mitteln |
CN104815331A (zh) | 2005-05-09 | 2015-08-05 | 生物领域医疗公司 | 使用微球和非离子型造影剂的组合物和方法 |
ES2554527T3 (es) * | 2006-01-24 | 2015-12-21 | Biocompatibles Uk Limited | Proceso para rellenar partículas poliméricas con un fármaco |
WO2007090127A2 (en) | 2006-01-30 | 2007-08-09 | Surgica Corporation | Compressible intravascular embolization particles and related methods and delivery systems |
DK2034951T3 (da) | 2006-06-22 | 2013-04-29 | Biocompatibles Uk Ltd | Rehydererbart farmaceutisk produkt |
EP1985286A1 (en) * | 2007-04-24 | 2008-10-29 | Biocompatibles UK Limited | Microspheres for treatment of brain tumours |
ES2552718T3 (es) * | 2007-05-11 | 2015-12-01 | Nerviano Medical Sciences S.R.L. | Composición farmacéutica de una antraciclina |
US20110229572A1 (en) * | 2007-08-16 | 2011-09-22 | Biocompatibles Uk Limited | Delivery of drug combinations |
EP3181123A1 (en) | 2008-12-02 | 2017-06-21 | Biocompatibles Uk Ltd. | Pancreatic tumour treatment |
GB201101429D0 (en) * | 2011-01-27 | 2011-03-16 | Biocompatibles Uk Ltd | Drug delivery system |
WO2014035206A2 (ko) | 2012-08-31 | 2014-03-06 | 중앙대학교 산학협력단 | 색전용 마이크로스피어의 제조방법 및 약물 함유 나노수송체가 결합된 마이크로스피어의 제조방법 |
CN117982687A (zh) | 2013-03-15 | 2024-05-07 | 生物兼容英国有限公司 | 可成像栓塞微球 |
GB2521997A (en) * | 2013-09-06 | 2015-07-15 | Biocompatibles Uk Ltd | Radiopaque polymers |
GB2519738A (en) * | 2013-09-06 | 2015-05-06 | Biocompatibles Uk Ltd | Radiopaque polymers |
BR112017018851B1 (pt) | 2015-03-02 | 2022-11-29 | Accurate Medical Therapeutics Ltd | Cateteres com aberturas laterais para modificar e distribuir suspensões a um sujeito |
GB201515602D0 (en) | 2015-09-03 | 2015-10-21 | Biocompatibles Uk Ltd | Polymers and microspheres |
KR20180125957A (ko) | 2016-03-14 | 2018-11-26 | 바이오컴패티블스 유케이 엘티디 | 입자를 포함하는 에멀전 |
WO2018093566A1 (en) | 2016-11-16 | 2018-05-24 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Imageable particles, methods of making and methods of use thereof |
EP3651737B1 (en) * | 2017-07-13 | 2023-05-10 | Varian Medical Systems Inc | Embolic microspheres |
CN111447882B (zh) | 2017-11-02 | 2024-05-24 | 阿克瑞特医学治疗有限公司 | 具有一体式过滤器的栓塞导管 |
JP7322073B2 (ja) | 2018-06-29 | 2023-08-07 | バイオコンパティブルズ ユーケー リミテッド | 放射線不透過性ポリマー |
US20200297635A1 (en) | 2019-03-22 | 2020-09-24 | Biocompatibles Uk Limited | Embolic microspheres and methods |
GB201910286D0 (en) | 2019-07-18 | 2019-09-04 | Biocompatibles Uk Ltd | Radiopaque polymers |
BR112022016960A2 (pt) * | 2020-02-25 | 2022-10-25 | Hepion Pharmaceuticals Inc | Uso de análogos de ciclosporina para tratamento de câncer |
CN113797383A (zh) * | 2021-09-28 | 2021-12-17 | 迪格瑞医疗科技(苏州)有限公司 | 一种高弹性、高载药量的栓塞微球及其制备方法 |
WO2023122292A1 (en) | 2021-12-23 | 2023-06-29 | Boston Scientific Medical Device Limited | Chemoembolic compositions and methods of treatment using them |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4978713A (en) * | 1987-12-16 | 1990-12-18 | Ciba-Geigy Corporation | Polyvinyl alcohol derivatives containing pendant vinylic monomer reaction product units bound through ether groups and hydrogel contact lenses made therefrom |
JP3041627B2 (ja) * | 1989-04-13 | 2000-05-15 | 武田薬品工業株式会社 | アントラサイクリン系抗生物質の安定組成物 |
JPH06329542A (ja) * | 1993-05-21 | 1994-11-29 | Kibun Food Chemifa Co Ltd | 不溶性アルギン酸塩粒子を含む局所血管止血用組成物および動脈化学塞栓用組成物 |
WO1995013798A1 (en) * | 1993-11-18 | 1995-05-26 | Cancer Research Institute Inc. | Controlled release preparation |
AU8877098A (en) * | 1997-09-05 | 1999-03-29 | Nycomed Imaging As | Polymer particles made of polyvinyl alcohol and comprising contrast agent for chemoembolization |
EP1263803B1 (en) * | 2000-03-13 | 2007-09-19 | BioCure, Inc. | Embolic compositions |
US6852816B2 (en) * | 2000-10-06 | 2005-02-08 | Biocompatibles Uk Limited | Zwitterionic polymers |
EP1556090A1 (en) * | 2002-09-25 | 2005-07-27 | Biocompatibles UK Limited | Polymer compositions for administration to animals |
-
2004
- 2004-02-12 CN CN201610844279.0A patent/CN106267325B/zh not_active Expired - Lifetime
- 2004-02-12 CN CN201310320841.6A patent/CN103393605B/zh not_active Expired - Lifetime
- 2004-02-12 AT AT04710431T patent/ATE396708T1/de not_active IP Right Cessation
- 2004-02-12 WO PCT/GB2004/000548 patent/WO2004071495A1/en active IP Right Grant
- 2004-02-12 EP EP04710431A patent/EP1592405B1/en not_active Expired - Lifetime
- 2004-02-12 DE DE602004014101T patent/DE602004014101D1/de not_active Expired - Lifetime
- 2004-02-12 KR KR1020057014847A patent/KR101157260B1/ko active IP Right Grant
- 2004-02-12 CN CN201210299592.2A patent/CN102895662B/zh not_active Expired - Lifetime
- 2004-02-12 ES ES04710431T patent/ES2308149T3/es not_active Expired - Lifetime
- 2004-02-12 JP JP2006500252A patent/JP4895802B2/ja not_active Expired - Lifetime
- 2004-02-12 CN CN201410044028.5A patent/CN103908704B/zh not_active Expired - Lifetime
-
2005
- 2005-12-30 HK HK05112166.8A patent/HK1079980B/zh not_active IP Right Cessation
-
2011
- 2011-02-21 JP JP2011034961A patent/JP5616251B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE602004014101D1 (de) | 2008-07-10 |
JP2011178784A (ja) | 2011-09-15 |
JP2006515358A (ja) | 2006-05-25 |
CN106267325A (zh) | 2017-01-04 |
WO2004071495A1 (en) | 2004-08-26 |
ES2308149T3 (es) | 2008-12-01 |
JP4895802B2 (ja) | 2012-03-14 |
JP5616251B2 (ja) | 2014-10-29 |
CN103393605A (zh) | 2013-11-20 |
HK1079980A1 (en) | 2006-04-21 |
CN103393605B (zh) | 2018-05-29 |
CN103908704B (zh) | 2017-09-01 |
ATE396708T1 (de) | 2008-06-15 |
CN102895662B (zh) | 2017-09-12 |
EP1592405A1 (en) | 2005-11-09 |
EP1592405B1 (en) | 2008-05-28 |
CN103908704A (zh) | 2014-07-09 |
CN106267325B (zh) | 2019-09-24 |
CN102895662A (zh) | 2013-01-30 |
KR20050103224A (ko) | 2005-10-27 |
KR101157260B1 (ko) | 2012-06-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20230217 |