HK1079980B - 硬瘤化學栓塞治療成分 - Google Patents
硬瘤化學栓塞治療成分Info
- Publication number
- HK1079980B HK1079980B HK05112166.8A HK05112166A HK1079980B HK 1079980 B HK1079980 B HK 1079980B HK 05112166 A HK05112166 A HK 05112166A HK 1079980 B HK1079980 B HK 1079980B
- Authority
- HK
- Hong Kong
- Prior art keywords
- chemoembolotherapy
- composition
- solid tumors
- polymer
- water
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/06—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/001—Use of materials characterised by their function or physical properties
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/001—Use of materials characterised by their function or physical properties
- A61L24/0015—Medicaments; Biocides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F2/00—Processes of polymerisation
- C08F2/12—Polymerisation in non-solvents
- C08F2/14—Organic medium
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
- C08F290/08—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated side groups
- C08F290/12—Polymers provided for in subclasses C08C or C08F
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/48—Isomerisation; Cyclisation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/23—Carbohydrates
- A61L2300/232—Monosaccharides, disaccharides, polysaccharides, lipopolysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/06—Flowable or injectable implant compositions
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F2810/00—Chemical modification of a polymer
- C08F2810/30—Chemical modification of a polymer leading to the formation or introduction of aliphatic or alicyclic unsaturated groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Materials Engineering (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP03250868 | 2003-02-12 | ||
GB0305322A GB0305322D0 (en) | 2003-03-07 | 2003-03-07 | Chemoembolisation |
PCT/GB2004/000548 WO2004071495A1 (en) | 2003-02-12 | 2004-02-12 | Composition for chemoembolotherapy of solid tumors |
Publications (2)
Publication Number | Publication Date |
---|---|
HK1079980A1 HK1079980A1 (en) | 2006-04-21 |
HK1079980B true HK1079980B (zh) | 2008-11-14 |
Family
ID=32870779
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK05112166.8A HK1079980B (zh) | 2003-02-12 | 2005-12-30 | 硬瘤化學栓塞治療成分 |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP1592405B1 (zh) |
JP (2) | JP4895802B2 (zh) |
KR (1) | KR101157260B1 (zh) |
CN (4) | CN103393605B (zh) |
AT (1) | ATE396708T1 (zh) |
DE (1) | DE602004014101D1 (zh) |
ES (1) | ES2308149T3 (zh) |
HK (1) | HK1079980B (zh) |
WO (1) | WO2004071495A1 (zh) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1430505A (zh) | 2000-03-24 | 2003-07-16 | 生物领域医疗公司 | 用于主动栓塞术的微球体 |
WO2005087193A2 (en) * | 2004-03-11 | 2005-09-22 | Biocompatibles Uk Limited | Chemoembolisation involving an anthracycline compound |
WO2006027567A2 (en) * | 2004-09-07 | 2006-03-16 | Biocompatibles Uk Limited | Drug delivery from embolic agents |
WO2006119968A2 (en) | 2005-05-09 | 2006-11-16 | Biosphere Medical S.A. | Compositions and methods using microspheres and non-ionic contrast agents |
EP1978938B1 (en) * | 2006-01-24 | 2015-09-09 | Biocompatibles UK Limited | Process for loading polymer particles with drug |
EP1986707A2 (en) | 2006-01-30 | 2008-11-05 | Surgica Corporation | Compressible intravascular embolization particles and related methods and delivery systems |
SI2034951T1 (sl) * | 2006-06-22 | 2013-06-28 | Biocompatibles Uk Limited | Rehidrirajoč farmacevtski proizvod |
EP1985286A1 (en) | 2007-04-24 | 2008-10-29 | Biocompatibles UK Limited | Microspheres for treatment of brain tumours |
JP5302300B2 (ja) * | 2007-05-11 | 2013-10-02 | ネルビアーノ・メデイカル・サイエンシーズ・エツセ・エルレ・エルレ | アンスラサイクリンの医薬組成物 |
ES2706023T3 (es) * | 2007-08-16 | 2019-03-27 | Biocompatibles Uk Ltd | Administración de combinaciones de fármacos |
CA2745238A1 (en) * | 2008-12-02 | 2010-06-10 | Biocompatibles Uk Limited | Pancreatic tumour treatment |
GB201101429D0 (en) * | 2011-01-27 | 2011-03-16 | Biocompatibles Uk Ltd | Drug delivery system |
US20150224221A1 (en) | 2012-08-31 | 2015-08-13 | Chung-Ang University Industry-Academic Cooperation Foundation | Method for preparing microspheres for emboli, and method for preparing microspheres to which drug-containing carrier is bound |
US10307493B2 (en) | 2013-03-15 | 2019-06-04 | Biocompatible UK Limited | Imageable embolic microsphere |
GB2521997A (en) * | 2013-09-06 | 2015-07-15 | Biocompatibles Uk Ltd | Radiopaque polymers |
GB2519738A (en) * | 2013-09-06 | 2015-05-06 | Biocompatibles Uk Ltd | Radiopaque polymers |
US11344314B2 (en) * | 2015-03-02 | 2022-05-31 | Accurate Medical Therapeutics Ltd. | Catheters with side openings for modifying and delivering suspensions to a subject |
GB201515602D0 (en) | 2015-09-03 | 2015-10-21 | Biocompatibles Uk Ltd | Polymers and microspheres |
JP7014728B2 (ja) | 2016-03-14 | 2022-02-01 | バイオコンパティブルズ ユーケー リミテッド | 粒子を含むエマルジョン |
US11382990B2 (en) | 2016-11-16 | 2022-07-12 | The Usa, As Represented By The Secretary, Dhhs | Imageable polymers, methods of making and methods of use thereof |
CN110891550B (zh) * | 2017-07-13 | 2023-03-07 | 瓦里安医疗系统公司 | 栓塞微球 |
CN111447882A (zh) | 2017-11-02 | 2020-07-24 | 阿克瑞特医学治疗有限公司 | 具有一体式过滤器的栓塞导管 |
US11702498B2 (en) | 2018-06-29 | 2023-07-18 | Biocompatibles Uk Limited | Radiopaque polymers |
CN113727699A (zh) | 2019-03-22 | 2021-11-30 | 生物相容英国有限公司 | 栓塞微球和方法 |
GB201910286D0 (en) | 2019-07-18 | 2019-09-04 | Biocompatibles Uk Ltd | Radiopaque polymers |
AR121404A1 (es) * | 2020-02-25 | 2022-06-01 | Hepion Pharmaceuticals Inc | Uso de análogos de ciclosporina para tratar cáncer |
CN113797383A (zh) * | 2021-09-28 | 2021-12-17 | 迪格瑞医疗科技(苏州)有限公司 | 一种高弹性、高载药量的栓塞微球及其制备方法 |
US20230201122A1 (en) | 2021-12-23 | 2023-06-29 | Boston Scientific Medical Device Limited | Chemoembolic compositions and methods of treatment using them |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4978713A (en) * | 1987-12-16 | 1990-12-18 | Ciba-Geigy Corporation | Polyvinyl alcohol derivatives containing pendant vinylic monomer reaction product units bound through ether groups and hydrogel contact lenses made therefrom |
JP3041627B2 (ja) * | 1989-04-13 | 2000-05-15 | 武田薬品工業株式会社 | アントラサイクリン系抗生物質の安定組成物 |
JPH06329542A (ja) * | 1993-05-21 | 1994-11-29 | Kibun Food Chemifa Co Ltd | 不溶性アルギン酸塩粒子を含む局所血管止血用組成物および動脈化学塞栓用組成物 |
DE69432867T2 (de) * | 1993-11-18 | 2004-04-22 | Sirtex Medical Ltd., Burswood | Zubereitung mit gesteuerter freisetzung |
AU8877098A (en) * | 1997-09-05 | 1999-03-29 | Nycomed Imaging As | Polymer particles made of polyvinyl alcohol and comprising contrast agent for chemoembolization |
US6676971B2 (en) * | 2000-03-13 | 2004-01-13 | Biocure, Inc. | Embolic compositions |
ATE365753T1 (de) * | 2000-10-06 | 2007-07-15 | Biocompatibles Uk Ltd | Zwitterionische polymere |
WO2004028569A1 (en) * | 2002-09-25 | 2004-04-08 | Biocompatibles Uk Limited | Polymer compositions for administration to animals |
-
2004
- 2004-02-12 ES ES04710431T patent/ES2308149T3/es not_active Expired - Lifetime
- 2004-02-12 DE DE602004014101T patent/DE602004014101D1/de not_active Expired - Lifetime
- 2004-02-12 CN CN201310320841.6A patent/CN103393605B/zh not_active Expired - Lifetime
- 2004-02-12 CN CN201610844279.0A patent/CN106267325B/zh not_active Expired - Lifetime
- 2004-02-12 WO PCT/GB2004/000548 patent/WO2004071495A1/en active IP Right Grant
- 2004-02-12 KR KR1020057014847A patent/KR101157260B1/ko active IP Right Grant
- 2004-02-12 CN CN201210299592.2A patent/CN102895662B/zh not_active Expired - Lifetime
- 2004-02-12 EP EP04710431A patent/EP1592405B1/en not_active Expired - Lifetime
- 2004-02-12 CN CN201410044028.5A patent/CN103908704B/zh not_active Expired - Lifetime
- 2004-02-12 JP JP2006500252A patent/JP4895802B2/ja not_active Expired - Lifetime
- 2004-02-12 AT AT04710431T patent/ATE396708T1/de not_active IP Right Cessation
-
2005
- 2005-12-30 HK HK05112166.8A patent/HK1079980B/zh not_active IP Right Cessation
-
2011
- 2011-02-21 JP JP2011034961A patent/JP5616251B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CN106267325A (zh) | 2017-01-04 |
CN103393605B (zh) | 2018-05-29 |
CN103908704A (zh) | 2014-07-09 |
CN102895662B (zh) | 2017-09-12 |
DE602004014101D1 (de) | 2008-07-10 |
JP2011178784A (ja) | 2011-09-15 |
CN102895662A (zh) | 2013-01-30 |
JP5616251B2 (ja) | 2014-10-29 |
HK1079980A1 (en) | 2006-04-21 |
KR101157260B1 (ko) | 2012-06-15 |
ATE396708T1 (de) | 2008-06-15 |
KR20050103224A (ko) | 2005-10-27 |
CN106267325B (zh) | 2019-09-24 |
ES2308149T3 (es) | 2008-12-01 |
JP4895802B2 (ja) | 2012-03-14 |
CN103908704B (zh) | 2017-09-01 |
JP2006515358A (ja) | 2006-05-25 |
CN103393605A (zh) | 2013-11-20 |
EP1592405A1 (en) | 2005-11-09 |
WO2004071495A1 (en) | 2004-08-26 |
EP1592405B1 (en) | 2008-05-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20230217 |