HK1078783A1 - Multistage formulation containing a biguanide and thiazolidindione derivatives - Google Patents

Multistage formulation containing a biguanide and thiazolidindione derivatives

Info

Publication number
HK1078783A1
HK1078783A1 HK05110822.8A HK05110822A HK1078783A1 HK 1078783 A1 HK1078783 A1 HK 1078783A1 HK 05110822 A HK05110822 A HK 05110822A HK 1078783 A1 HK1078783 A1 HK 1078783A1
Authority
HK
Hong Kong
Prior art keywords
biguanide
multistage
formulation containing
thiazolidindione
derivatives
Prior art date
Application number
HK05110822.8A
Other languages
English (en)
Inventor
Unchalee Kositprapa
Avinash Nangia
John Cardinal
Robert I Goldfarb
Original Assignee
Watson Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Watson Pharmaceuticals Inc filed Critical Watson Pharmaceuticals Inc
Publication of HK1078783A1 publication Critical patent/HK1078783A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK05110822.8A 2002-09-20 2005-11-28 Multistage formulation containing a biguanide and thiazolidindione derivatives HK1078783A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41218002P 2002-09-20 2002-09-20
US41218102P 2002-09-20 2002-09-20
PCT/US2003/029292 WO2004026241A2 (en) 2002-09-20 2003-09-19 Multistage formulation containing a biguanide and thiazolidindione derivatives

Publications (1)

Publication Number Publication Date
HK1078783A1 true HK1078783A1 (en) 2006-03-24

Family

ID=32033587

Family Applications (2)

Application Number Title Priority Date Filing Date
HK05110822.8A HK1078783A1 (en) 2002-09-20 2005-11-28 Multistage formulation containing a biguanide and thiazolidindione derivatives
HK10104549.6A HK1136780A1 (en) 2002-09-20 2010-05-11 Multistage formulation containing a biguanide and thiazolidindione derivatives

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK10104549.6A HK1136780A1 (en) 2002-09-20 2010-05-11 Multistage formulation containing a biguanide and thiazolidindione derivatives

Country Status (9)

Country Link
EP (2) EP1539144B1 (zh)
JP (1) JP4694841B2 (zh)
KR (4) KR20050053677A (zh)
CN (2) CN100544717C (zh)
AU (1) AU2003272504A1 (zh)
CA (1) CA2499597C (zh)
ES (1) ES2529180T3 (zh)
HK (2) HK1078783A1 (zh)
WO (1) WO2004026241A2 (zh)

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US7785627B2 (en) * 2002-09-20 2010-08-31 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
EP1588708A4 (en) 2003-01-29 2006-03-01 Takeda Pharmaceutical METHOD FOR PRODUCING COATED PREPARATION
UY29445A1 (es) * 2005-03-30 2006-10-02 Generex Pharm Inc Composiciones para la transmisión transmucosa oral de la metformina
CA2633167A1 (en) * 2005-12-16 2007-07-12 Merck & Co., Inc. Pharmaceutical compositions of combinations of dipeptidyl peptidase-4 inhibitors with metformin
US8747897B2 (en) * 2006-04-27 2014-06-10 Supernus Pharmaceuticals, Inc. Osmotic drug delivery system
TWI407959B (zh) * 2006-05-23 2013-09-11 Takeda Pharmaceutical 口服製劑
DE102008059206A1 (de) * 2008-11-27 2010-06-10 Bayer Schering Pharma Aktiengesellschaft Pharmazeutische Darreichungsform enthaltend Nifedipin oder Nisoldipin und einen Angiotensin-II Antagonisten und/oder ein Diuretikum
WO2011083998A2 (ko) 2010-01-06 2011-07-14 한올바이오파마주식회사 바이구아나이드 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 약학 조성물
MX2012015188A (es) * 2010-06-22 2013-05-20 Twi Pharmaceuticals Inc Composiciones de liberacion controlada con efecto de alimentos reducido.
WO2012028934A1 (en) 2010-09-01 2012-03-08 Lupin Limited Pharmaceutical composition comprising metformin and pioglitazone
CN102008472B (zh) * 2010-10-18 2012-08-22 中国科学院上海药物研究所 一种复方盐酸吡格列酮/盐酸二甲双胍双层渗透泵控释制剂及其制备方法
CN101984974B (zh) * 2010-11-15 2013-04-17 山东新华制药股份有限公司 一种用于治疗2型糖尿病的药物组合物的制备方法
CN105663130B (zh) * 2011-04-15 2019-08-09 江苏豪森药业集团有限公司 一种具有第一和第二活性药物的制剂
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CN102920704A (zh) * 2012-11-05 2013-02-13 上海现代药物制剂工程研究中心有限公司 含有双胍和噻唑烷二酮衍生物的药物制剂
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CN104473894A (zh) * 2014-12-18 2015-04-01 浙江华海药业股份有限公司 一种盐酸吡格列酮载药包衣制剂及其制备方法
CN106137999A (zh) * 2015-03-31 2016-11-23 深圳翰宇药业股份有限公司 一种复方吡格列酮二甲双胍缓释片及其制备方法
KR101750690B1 (ko) * 2015-10-28 2017-06-27 주식회사 종근당 메트포르민 및 로베글리타존을 포함하는 약제학적 조성물
CN108478537A (zh) * 2018-05-03 2018-09-04 南京易亨制药有限公司 一种含普瑞巴林的单室渗透泵控释片剂
WO2021242040A1 (ko) * 2020-05-29 2021-12-02 한국유나이티드제약 주식회사 삼투압에 의해 방출 조절되는 서방성 메트포르민 코팅 정제 및 이의 제조방법

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Also Published As

Publication number Publication date
CN1681496A (zh) 2005-10-12
KR20100137023A (ko) 2010-12-29
CN101623274A (zh) 2010-01-13
CA2499597C (en) 2012-01-17
KR20130039344A (ko) 2013-04-19
KR20120034211A (ko) 2012-04-10
CN101623274B (zh) 2012-06-27
WO2004026241A2 (en) 2004-04-01
EP2604266A1 (en) 2013-06-19
AU2003272504A1 (en) 2004-04-08
EP1539144B1 (en) 2014-12-24
KR101363679B1 (ko) 2014-02-14
AU2003272504A8 (en) 2004-04-08
HK1136780A1 (en) 2010-07-09
JP2006502187A (ja) 2006-01-19
CA2499597A1 (en) 2004-04-01
EP1539144A4 (en) 2010-06-09
KR20050053677A (ko) 2005-06-08
JP4694841B2 (ja) 2011-06-08
CN100544717C (zh) 2009-09-30
WO2004026241A3 (en) 2004-06-10
ES2529180T3 (es) 2015-02-17
EP1539144A2 (en) 2005-06-15

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20170919