HK1074998A1 - Non-nucleosidic inhibitors of reverse transcriptase as antagonists of cell proliferation and inducers of cell differentiation - Google Patents

Non-nucleosidic inhibitors of reverse transcriptase as antagonists of cell proliferation and inducers of cell differentiation

Info

Publication number
HK1074998A1
HK1074998A1 HK05107274.7A HK05107274A HK1074998A1 HK 1074998 A1 HK1074998 A1 HK 1074998A1 HK 05107274 A HK05107274 A HK 05107274A HK 1074998 A1 HK1074998 A1 HK 1074998A1
Authority
HK
Hong Kong
Prior art keywords
inducers
antagonists
reverse transcriptase
cell
cell proliferation
Prior art date
Application number
HK05107274.7A
Other languages
English (en)
Inventor
Corrado Spadafora
Patrizia Lavia
Elisabetta Mattei
Guglielmo Palombini
Rodolfo Nello Lorenzini
Clara Nervi
Original Assignee
Ist Superiore Sanita
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ITRM20010767 external-priority patent/ITRM20010767A1/it
Priority claimed from ITMI20021833 external-priority patent/ITMI20021833A1/it
Application filed by Ist Superiore Sanita filed Critical Ist Superiore Sanita
Publication of HK1074998A1 publication Critical patent/HK1074998A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/536—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK05107274.7A 2001-12-24 2005-08-22 Non-nucleosidic inhibitors of reverse transcriptase as antagonists of cell proliferation and inducers of cell differentiation HK1074998A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITRM20010767 ITRM20010767A1 (it) 2001-12-24 2001-12-24 Uso di 5.11-diidro-6h-dipirido1/4 3,2-b:2',3'-e|1/4 1.4|diazepine per la preparazione di composizioni farmaceutiche antitumorali.
ITMI20021833 ITMI20021833A1 (it) 2002-08-19 2002-08-19 Inibitori non nucleosidici della trascrittasi inversa come induttori del differenziamento cellulare.
PCT/EP2002/014727 WO2003055493A1 (en) 2001-12-24 2002-12-23 Non-nucleosidic inhibitors of reverse transcriptase as antagonists of cell proliferation and inducers of cell differentiation

Publications (1)

Publication Number Publication Date
HK1074998A1 true HK1074998A1 (en) 2005-12-02

Family

ID=26332794

Family Applications (1)

Application Number Title Priority Date Filing Date
HK05107274.7A HK1074998A1 (en) 2001-12-24 2005-08-22 Non-nucleosidic inhibitors of reverse transcriptase as antagonists of cell proliferation and inducers of cell differentiation

Country Status (23)

Country Link
US (1) US10507207B2 (es)
EP (1) EP1469858B1 (es)
JP (1) JP4336584B2 (es)
CN (1) CN100450487C (es)
AP (1) AP1958A (es)
AT (1) ATE400276T1 (es)
AU (1) AU2002358793B2 (es)
CA (1) CA2471543C (es)
CY (1) CY1108396T1 (es)
DE (1) DE60227563D1 (es)
DK (1) DK1469858T3 (es)
EA (1) EA007004B1 (es)
ES (1) ES2309222T3 (es)
HK (1) HK1074998A1 (es)
HU (1) HU229522B1 (es)
IL (2) IL162680A0 (es)
MX (1) MXPA04006205A (es)
NZ (1) NZ534257A (es)
OA (1) OA13140A (es)
PL (1) PL211565B1 (es)
PT (1) PT1469858E (es)
SI (1) SI1469858T1 (es)
WO (1) WO2003055493A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010081823A1 (en) 2009-01-13 2010-07-22 Proteosys Ag Pirenzepine as otoprotective agent
WO2011151786A2 (en) * 2010-06-04 2011-12-08 North-West University Injectable formulation
MX2015009546A (es) * 2013-01-23 2015-11-25 Alienor Farma Dosificacion aumentada de efavirenz para el tratamiento de cancer.
WO2016156557A1 (en) 2015-04-03 2016-10-06 Alienor Farma Monoclonal antibody to human line-1 orf2 protein and method for early detection of transforming cells in pre-neoplastic tissues of a human subject
CN113384585A (zh) * 2021-04-16 2021-09-14 蓝龙药业(北京)有限公司 依法韦仑在制备治疗小细胞肺癌的药物中的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6258839B1 (en) * 1997-12-24 2001-07-10 Peter Mashava Isolation of naturally occuring isoflavanone and some clinical uses thereof

Also Published As

Publication number Publication date
AP1958A (en) 2009-02-20
CY1108396T1 (el) 2014-02-12
JP2005513147A (ja) 2005-05-12
US20060166970A1 (en) 2006-07-27
PL211565B1 (pl) 2012-05-31
EP1469858A1 (en) 2004-10-27
WO2003055493A1 (en) 2003-07-10
HUP0600841A2 (en) 2007-05-02
AU2002358793A1 (en) 2003-07-15
CN100450487C (zh) 2009-01-14
HU229522B1 (en) 2014-01-28
SI1469858T1 (sl) 2008-10-31
EA200400861A1 (ru) 2004-12-30
AU2002358793B2 (en) 2008-04-24
IL162680A (en) 2010-11-30
HUP0600841A3 (en) 2012-09-28
CN1607953A (zh) 2005-04-20
EA007004B1 (ru) 2006-06-30
ES2309222T3 (es) 2008-12-16
ATE400276T1 (de) 2008-07-15
DK1469858T3 (da) 2008-09-29
PL374038A1 (en) 2005-09-19
MXPA04006205A (es) 2005-07-25
AP2004003088A0 (en) 2004-09-30
EP1469858B1 (en) 2008-07-09
JP4336584B2 (ja) 2009-09-30
OA13140A (en) 2006-12-13
US10507207B2 (en) 2019-12-17
NZ534257A (en) 2008-03-28
CA2471543A1 (en) 2003-07-10
PT1469858E (pt) 2008-10-01
IL162680A0 (en) 2005-11-20
CA2471543C (en) 2011-03-22
DE60227563D1 (de) 2008-08-21

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20171223