HK1073997A1 - Administration of agents for the treatment of inflammation - Google Patents

Administration of agents for the treatment of inflammation

Info

Publication number
HK1073997A1
HK1073997A1 HK05105001.1A HK05105001A HK1073997A1 HK 1073997 A1 HK1073997 A1 HK 1073997A1 HK 05105001 A HK05105001 A HK 05105001A HK 1073997 A1 HK1073997 A1 HK 1073997A1
Authority
HK
Hong Kong
Prior art keywords
inflammation
administration
agents
treatment
Prior art date
Application number
HK05105001.1A
Other languages
English (en)
Inventor
Julie Taylor
Ted A Yednock
Original Assignee
Elan Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27767592&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1073997(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Elan Pharm Inc filed Critical Elan Pharm Inc
Publication of HK1073997A1 publication Critical patent/HK1073997A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2842—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta1-subunit-containing molecules, e.g. CD29, CD49
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507—Comprising a combination of two or more separate antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4737—C-reactive protein
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70546—Integrin superfamily, e.g. VLAs, leuCAM, GPIIb/GPIIIa, LPAM
    • G01N2333/7055—Integrin beta1-subunit-containing molecules, e.g. CD29, CD49

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Mycology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Virology (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
HK05105001.1A 2002-02-25 2005-06-15 Administration of agents for the treatment of inflammation HK1073997A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US36013402P 2002-02-25 2002-02-25
US37450102P 2002-04-23 2002-04-23
PCT/US2003/005421 WO2003072040A2 (fr) 2002-02-25 2003-02-25 Administration d'agents pour le traitement d'une inflammation

Publications (1)

Publication Number Publication Date
HK1073997A1 true HK1073997A1 (en) 2005-10-28

Family

ID=27767592

Family Applications (1)

Application Number Title Priority Date Filing Date
HK05105001.1A HK1073997A1 (en) 2002-02-25 2005-06-15 Administration of agents for the treatment of inflammation

Country Status (28)

Country Link
US (7) US20040009169A1 (fr)
EP (6) EP2289941A3 (fr)
JP (3) JP2005526045A (fr)
KR (1) KR20040105740A (fr)
CN (1) CN1310678C (fr)
AR (1) AR038605A1 (fr)
AT (1) ATE512163T1 (fr)
AU (2) AU2003213231A1 (fr)
BR (1) BR0307975A (fr)
CA (1) CA2477178A1 (fr)
CO (1) CO5611176A2 (fr)
CY (1) CY1111787T1 (fr)
DK (2) DK2336184T3 (fr)
ES (1) ES2531852T3 (fr)
HK (1) HK1073997A1 (fr)
IL (3) IL163725A0 (fr)
MX (1) MXPA04008267A (fr)
MY (1) MY157727A (fr)
NO (1) NO336235B1 (fr)
NZ (3) NZ579583A (fr)
PL (1) PL215263B1 (fr)
PT (2) PT2336184E (fr)
RU (1) RU2359697C2 (fr)
SA (1) SA03240276A (fr)
SI (2) SI1485127T1 (fr)
TW (2) TW201125584A (fr)
WO (1) WO2003072040A2 (fr)
ZA (1) ZA200407406B (fr)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040009169A1 (en) 2002-02-25 2004-01-15 Julie Taylor Administration of agents for the treatment of inflammation
EP2287199B1 (fr) 2002-03-13 2017-08-02 Biogen MA Inc. Anticorps anti-alpha V bêta 6
WO2004066931A2 (fr) * 2003-01-24 2004-08-12 Elan Pharmaceuticals Inc. Composition et methode destinees a traiter les maladies de demyelinisation et la paralysie par administration d'agents de remyelinisation
AU2004210679A1 (en) * 2003-02-10 2004-08-26 Elan Pharmaceuticals, Inc. Immunoglobulin formulation and method of preparation thereof
US20050074451A1 (en) * 2003-06-25 2005-04-07 Elan Pharmaceuticals, Inc. Methods and compositions for treating rheumatoid arthritis
PE20051053A1 (es) 2004-01-09 2005-12-12 Pfizer ANTICUERPOS CONTRA MAdCAM
AU2005213324B2 (en) * 2004-02-06 2011-06-09 Biogen Idec Ma Inc. Methods and compositions for treating tumors and metastatic disease
AU2011213878B2 (en) * 2004-04-01 2012-06-14 Biogen Ma Inc. Steroid sparing agents and methods of using same
MY162179A (en) 2004-04-01 2017-05-31 Elan Pharm Inc Steroid sparing agents and methods of using same
CA2478458A1 (fr) * 2004-08-20 2006-02-20 Michael Panzara Traitement de la sclerose en plaques pediatrique
AU2011232775B2 (en) * 2004-08-20 2013-11-28 Biogen Ma Inc. Extended Treatment of Multiple Sclerosis
CN101102792A (zh) * 2004-11-19 2008-01-09 比奥根艾迪克Ma公司 治疗多发性硬化
AU2012202575B2 (en) * 2004-11-19 2014-11-20 Biogen Ma Inc. Treatment for Multiple Sclerosis
CA2589379A1 (fr) * 2004-12-03 2006-06-08 Biogen Idec Ma Inc. Retardement ou prevention de l'apparition d'une sclerose en plaques
DK1835922T3 (da) * 2004-12-22 2009-08-03 Merck Serono Sa Kombinationsbehandling mod multipel sklerose
US20100167983A1 (en) * 2007-10-22 2010-07-01 Teva Pharmaceutical Industries, Ltd. Combination therapy with glatiramer acetate and rasagiline for the treatment of multiple sclerosis
PT1848415E (pt) * 2005-02-17 2013-06-27 Teva Pharma Terapia de combinação com acetato de glatirâmero e rasagilina para o tratamento da esclerose múltipla
EP1872136B9 (fr) 2005-04-04 2023-02-08 Biogen MA Inc. Procedes et produits pour evaluer une reponse immunitaire a une proteine therapeutique
AU2012202823B2 (en) * 2005-04-04 2014-09-25 Biogen Ma Inc. Methods and Products for Evaluating an Immune Response to a Therapeutic Protein
CN104072614B (zh) 2005-07-08 2017-04-26 生物基因Ma公司 抗-αvβ6 抗体及其用途
WO2007007160A2 (fr) * 2005-07-11 2007-01-18 Pfizer Limited Anticorps anti-madcam servant a traiter la fievre
WO2007100763A2 (fr) * 2006-02-28 2007-09-07 Elan Pharmaceuticals, Inc. Méthodes pour traiter des maladies inflammatoires et auto-immunes avec des composés inhibiteurs alpha-4
LT2676967T (lt) 2006-02-28 2019-09-10 Biogen Ma Inc. Uždegiminių ir autoimuninių ligų gydymo būdai su natalizumabu
KR20080104343A (ko) 2006-03-03 2008-12-02 엘란 파마슈티칼스, 인크. 나탈리주마브로 염증 및 자가면역 질환을 치료하는 방법
SG173364A1 (en) 2006-07-10 2011-08-29 Biogen Idec Inc Compositions and methods for inhibiting growth of smad4-deficient cancers
WO2008021954A2 (fr) * 2006-08-09 2008-02-21 Biogen Idec Ma Inc. Procédé de distribution d'un médicament
EP2109480B1 (fr) 2006-12-07 2017-06-28 The Government of the United States of America as Represented by the Secretary of the Department of Health and Human Services Utilisation d'antagonistes de l'interaction entre gp120 du vih et l'integrine alpha4beta7
BRPI0901298A2 (pt) 2009-04-06 2011-01-04 Ems Sa derivados ftalimìdicos de compostos antiinflamatórios não-esteróide e/ou moduladores de tnf-(alfa), processo de sua obtenção, composições farmacêuticas contendo os mesmos e seus usos no tratamento de doenças inflamatórias
CA2758548A1 (fr) * 2009-04-17 2010-10-21 Biogen Idec Ma Inc. Compositions et procedes pour traiter une leucemie myelogene aigue
EP2467159A1 (fr) * 2009-08-20 2012-06-27 INSERM (Institut National de la Santé et de la Recherche Médicale) Vla-4 en tant que biomarqueur pour le pronostic et le ciblage pour thérapie dans la dystrophie musculaire de duchenne
CA2776756A1 (fr) 2009-10-11 2011-04-14 Biogen Idec Ma Inc. Tests associes a un anti-vla-4
US11287423B2 (en) 2010-01-11 2022-03-29 Biogen Ma Inc. Assay for JC virus antibodies
LT3339865T (lt) 2010-01-11 2022-12-12 Biogen Ma Inc. Tyrimas, skirtas antikūnams prieš jc virusą nustatyti
PL2558499T3 (pl) 2010-04-16 2017-10-31 Biogen Ma Inc Przeciwciała anty-VLA-4
EP3326645B1 (fr) 2010-10-25 2020-03-18 Biogen MA Inc. Procédés de détermination de différences dans l'activité alpha-4 intégrine par la corrélation de différences des taux de svcam et/ou de smadcam
MX2013011130A (es) * 2011-03-31 2013-10-30 Genentech Inc Metodos de administracion de antagonistas de integrina beta7.
EP2704742B1 (fr) 2011-05-02 2017-07-12 Millennium Pharmaceuticals, Inc. Formulation pour un anticorps anti- 4 7
UA116189C2 (uk) 2011-05-02 2018-02-26 Мілленніум Фармасьютікалз, Інк. КОМПОЗИЦІЯ АНТИ-α4β7 АНТИТІЛА
JP6243838B2 (ja) 2011-05-31 2017-12-06 バイオジェン・エムエイ・インコーポレイテッドＢｉｏｇｅｎ ＭＡ Ｉｎｃ． Ｐｍｌの危険性を査定する方法
EP2802319B1 (fr) * 2012-01-12 2017-10-25 Pharma Two B Ltd. Polythérapie à base de doses fixes pour le traitement de la maladie de parkinson
EP3666188A1 (fr) * 2012-12-05 2020-06-17 Theranos IP Company, LLC Systèmes, dispositifs et procédés de collecte et de transport d'échantillons de fluides corporels
US10035860B2 (en) 2013-03-15 2018-07-31 Biogen Ma Inc. Anti-alpha V beta 6 antibodies and uses thereof
WO2014144466A1 (fr) 2013-03-15 2014-09-18 Biogen Idec Ma Inc. Anticorps anti-alpha ν bêta 6 et leurs utilisations
EP3004334A4 (fr) 2013-05-28 2016-12-21 Biogen Ma Inc Méthodes d'évaluation de risque de développement d'une lemp
EP3052189A4 (fr) * 2013-10-03 2017-11-01 Leuvas Therapeutics Modulation de l'activité leucocytaire dans le traitement d'une maladie dégénérative neuro-inflammatoire
US9763992B2 (en) 2014-02-13 2017-09-19 Father Flanagan's Boys' Home Treatment of noise induced hearing loss
WO2015152409A1 (fr) * 2014-04-04 2015-10-08 大鵬薬品工業株式会社 Médicament anti-tumoral contenant un composé taxane, et renforçateur d'effet anti-tumoral
WO2015169966A2 (fr) * 2014-05-09 2015-11-12 Nogra Pharma Limited Méthodes de traitement d'une maladie inflammatoire chronique de l'intestin
KR20170120601A (ko) * 2015-02-26 2017-10-31 제넨테크, 인크. 인테그린 베타7 길항제 및 크론병을 치료하는 방법
AU2016340080A1 (en) * 2015-10-16 2018-05-10 Northwestern University Pharmaceutical combination of an atypical antipsychotic and an NMDA modulator for the treatment of schizophrenia,bipolar disorder, cognitive impairment and major depressive disorder
AU2016366677A1 (en) * 2015-12-09 2018-07-26 Nantcell, Inc. Compositions and methods for treatment of HER2 positive metastatic breast cancer
CR20200076A (es) 2017-07-14 2020-06-10 Pfizer ANTICUERPOS CONTRA MAdCAM
US11312775B2 (en) 2017-07-20 2022-04-26 University Of Virginia Patent Foundation Methods for treatment or prevention of a neurological immunity disorder
WO2019200202A1 (fr) 2018-04-12 2019-10-17 Morphic Therapeutic, Inc. Antagonistes de l'intégrine humaine (alpha4) (beta7)
US20210147547A1 (en) * 2018-04-13 2021-05-20 Novartis Ag Dosage Regimens For Anti-Pd-L1 Antibodies And Uses Thereof
EP3800999A4 (fr) 2018-06-04 2022-06-01 Biogen MA Inc. Anticorps anti-vla-4 ayant une fonction effectrice réduite
JP7437490B2 (ja) 2019-10-16 2024-02-22 モーフィック セラピューティック，インコーポレイテッド ヒトインテグリン（アルファ－４）（ベータ－７）の阻害
WO2022160323A1 (fr) * 2021-01-31 2022-08-04 兰州大学 Application d'un analogue nucléosidique dans la préparation de médicaments pour la prévention ou le traitement de maladies gastro-intestinales
CA3215371A1 (fr) 2021-04-13 2022-10-20 Shibeshih Mitiku BELACHEW Compositions et methodes de traitement de lesions chroniques actives de la matiere blanche/syndrome radiologiquement isole
WO2023035000A1 (fr) * 2021-09-03 2023-03-09 Pliant Therapeutics, Inc. Modulation thérapeutique d'intégrines

Family Cites Families (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0832981A1 (fr) 1987-02-17 1998-04-01 Pharming B.V. Séquences d'ADN pour diriger des protéines vers les glandes mammaires, afin d'être secrétées efficacement
US5057540A (en) 1987-05-29 1991-10-15 Cambridge Biotech Corporation Saponin adjuvant
US4912094B1 (en) 1988-06-29 1994-02-15 Ribi Immunochem Research Inc. Modified lipopolysaccharides and process of preparation
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
IL162181A (en) 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
JPH037237A (ja) * 1989-03-14 1991-01-14 Sandoz Ag シクロスポリン類投与の新規用途および治療手段
HU212924B (en) 1989-05-25 1996-12-30 Chiron Corp Adjuvant formulation comprising a submicron oil droplet emulsion
IL95501A (en) 1989-09-01 1997-04-15 Hutchinson Fred Cancer Res Inhibition by antibodies of lymphocyte adherence to vascular endothelium utilizing an extracellular matrix receptor-ligand interaction, and pharmaceutical compositions containing said antibodies
US5730978A (en) * 1989-09-01 1998-03-24 Fred Hutchinson Cancer Research Center Inhibition of lymphocyte adherence with α4β1-specific antibodies
US5260210A (en) * 1989-09-27 1993-11-09 Rubin Lee L Blood-brain barrier model
US6033665A (en) * 1989-09-27 2000-03-07 Elan Pharmaceuticals, Inc. Compositions and methods for modulating leukocyte adhesion to brain endothelial cells
SE464961B (sv) 1989-11-15 1991-07-08 Volvo Ab Ledprotes, i synnerhet foer fingerleder
DE59008157D1 (de) 1989-11-20 1995-02-09 Wolfgang Becker Verfahren zur herstellung einer zahnprothese.
DE69120146T2 (de) 1990-01-12 1996-12-12 Cell Genesys Inc Erzeugung xenogener antikörper
GB9206318D0 (en) 1992-03-24 1992-05-06 Cambridge Antibody Tech Binding substances
US6172197B1 (en) 1991-07-10 2001-01-09 Medical Research Council Methods for producing members of specific binding pairs
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
US5264563A (en) 1990-08-24 1993-11-23 Ixsys Inc. Process for synthesizing oligonucleotides with random codons
ES2204890T3 (es) 1991-03-06 2004-05-01 Merck Patent Gmbh Anticuerpos monoclonales humanizados.
US6225447B1 (en) 1991-05-15 2001-05-01 Cambridge Antibody Technology Ltd. Methods for producing members of specific binding pairs
US5871907A (en) 1991-05-15 1999-02-16 Medical Research Council Methods for producing members of specific binding pairs
US5858657A (en) 1992-05-15 1999-01-12 Medical Research Council Methods for producing members of specific binding pairs
US5224539A (en) 1991-06-14 1993-07-06 Coen Company, Inc. Cooling system for air heaters and the like
WO1994004679A1 (fr) 1991-06-14 1994-03-03 Genentech, Inc. Procede pour fabriquer des anticorps humanises
LU91067I2 (fr) 1991-06-14 2004-04-02 Genentech Inc Trastuzumab et ses variantes et dérivés immuno chimiques y compris les immotoxines
ES2136092T3 (es) 1991-09-23 1999-11-16 Medical Res Council Procedimientos para la produccion de anticuerpos humanizados.
US5872215A (en) 1991-12-02 1999-02-16 Medical Research Council Specific binding members, materials and methods
ES2313867T3 (es) 1991-12-02 2009-03-16 Medical Research Council Produccion de anticuerpos anti-auto de repertorios de segmentos de anticuerpo expresados en la superficie de fagos.
DK0625912T3 (da) 1992-02-12 1997-10-27 Biogen Inc Behandling af inflammatorisk tarmsygdom
US5932214A (en) * 1994-08-11 1999-08-03 Biogen, Inc. Treatment for inflammatory bowel disease with VLA-4 blockers
US5733743A (en) 1992-03-24 1998-03-31 Cambridge Antibody Technology Limited Methods for producing members of specific binding pairs
US5336894A (en) 1992-04-21 1994-08-09 The United States Of America As Represented By The Secretary Of The Air Force Universal infrared heat source controller
CA2150262C (fr) 1992-12-04 2008-07-08 Kaspar-Philipp Holliger Proteines fixatrices multivalentes et multispecifiques, fabrication et utilisation
NZ261259A (en) 1993-01-12 1996-12-20 Biogen Inc Humanised recombinant anti-vla4 antibody and diagnostic compositions and medicaments
DK66493D0 (da) 1993-06-08 1993-06-08 Ferring A S Praeparater, isaer til brug ved behandling af inflammatoriske tarmsygdomme eller til at opnaa forbedret saarheling
US5827690A (en) 1993-12-20 1998-10-27 Genzyme Transgenics Corporatiion Transgenic production of antibodies in milk
US5840299A (en) 1994-01-25 1998-11-24 Athena Neurosciences, Inc. Humanized antibodies against leukocyte adhesion molecule VLA-4
EP0804237B8 (fr) 1994-01-25 2006-11-08 Elan Pharmaceuticals, Inc. Anticorps humanises diriges contre la molecule d'adhesion leucocytaire vla-4
GB9406974D0 (en) 1994-04-08 1994-06-01 Pharmaceutical Proteins Ltd Transgenic production
US6001809A (en) 1994-07-11 1999-12-14 Elan Pharmaceuticals, Inc. Inhibitors of leukocyte adhesion
ATE237342T1 (de) 1994-07-11 2003-05-15 Athena Neurosciences Inc Inhibitoren der leukozytenadhäsion
US6113898A (en) 1995-06-07 2000-09-05 Idec Pharmaceuticals Corporation Human B7.1-specific primatized antibodies and transfectomas expressing said antibodies
EP0876615A1 (fr) 1995-11-10 1998-11-11 Elan Corporation Plc Peptides accroissant le transport dans les tissus et procedes d'identification et d'utilisation correspondants
GB9712818D0 (en) 1996-07-08 1997-08-20 Cambridge Antibody Tech Labelling and selection of specific binding molecules
IL119989A0 (en) 1997-01-10 1997-04-15 Yeda Res & Dev Pharmaceutical compositions for oral treatment of multiple sclerosis
EP1005368B1 (fr) 1997-03-10 2009-09-02 Ottawa Hospital Research Institute Utilisation d'acides nucléiques contenat un dinucléotide CpG non-methylé combiné avec de l'aluminium en tant qu'adjuvants
DE69833654T2 (de) 1997-05-29 2006-12-14 Merck & Co., Inc. (A New Jersey Corp.) Biarylalkansäuren in der verwendung als zelladhäsionsinhibitoren
JP2002535376A (ja) 1999-01-29 2002-10-22 ミレニアム・ファーマシューティカルズ・インコーポレイテッド Ｃｃｒ１アンタゴニストを用いた脱髄性炎症性疾患の治療方法
US6387930B1 (en) * 1999-05-04 2002-05-14 Schering Corporation Piperidine derivatives useful as CCR5 antagonists
US20010046496A1 (en) * 2000-04-14 2001-11-29 Brettman Lee R. Method of administering an antibody
EP2287191B1 (fr) 2000-05-10 2016-10-12 Mayo Foundation For Medical Education And Research Anticorps igm humains dotés de la capacité d'induire une remyélinisation, utilisations diagnostiques et thérapeutiques pour le système nerveux central
US20040009169A1 (en) 2002-02-25 2004-01-15 Julie Taylor Administration of agents for the treatment of inflammation
WO2004066931A2 (fr) * 2003-01-24 2004-08-12 Elan Pharmaceuticals Inc. Composition et methode destinees a traiter les maladies de demyelinisation et la paralysie par administration d'agents de remyelinisation
AU2004210679A1 (en) * 2003-02-10 2004-08-26 Elan Pharmaceuticals, Inc. Immunoglobulin formulation and method of preparation thereof
US7163939B2 (en) 2003-11-05 2007-01-16 Abbott Laboratories Macrocyclic kinase inhibitors
CA2589379A1 (fr) * 2004-12-03 2006-06-08 Biogen Idec Ma Inc. Retardement ou prevention de l'apparition d'une sclerose en plaques
WO2006112951A2 (fr) * 2005-03-03 2006-10-26 Seedlings Life Science Ventures, Llc Methode de gestion des risques concernant les patients soumis a un traitement a base de natalizumab
EP1872136B9 (fr) * 2005-04-04 2023-02-08 Biogen MA Inc. Procedes et produits pour evaluer une reponse immunitaire a une proteine therapeutique
LT2676967T (lt) * 2006-02-28 2019-09-10 Biogen Ma Inc. Uždegiminių ir autoimuninių ligų gydymo būdai su natalizumabu

Also Published As

Publication number Publication date
EP1485127A4 (fr) 2006-02-01
WO2003072040A3 (fr) 2004-05-21
US20070025989A1 (en) 2007-02-01
CY1111787T1 (el) 2015-10-07
ATE512163T1 (de) 2011-06-15
NZ591635A (en) 2012-06-29
EP2336184B1 (fr) 2014-12-03
US7807167B2 (en) 2010-10-05
US11248051B2 (en) 2022-02-15
US20200148773A1 (en) 2020-05-14
SI1485127T1 (sl) 2011-09-30
TW200400047A (en) 2004-01-01
AR038605A1 (es) 2005-01-19
PT1485127E (pt) 2011-09-07
NO20044054L (no) 2004-11-24
ES2531852T3 (es) 2015-03-20
ZA200407406B (en) 2005-11-30
BR0307975A (pt) 2005-01-11
EP2336184A3 (fr) 2012-01-11
JP2011140493A (ja) 2011-07-21
NZ535320A (en) 2008-05-30
CN1646163A (zh) 2005-07-27
RU2359697C2 (ru) 2009-06-27
EP3674322A1 (fr) 2020-07-01
MXPA04008267A (es) 2004-11-10
SA03240276A (ar) 2005-12-03
EP3173426A1 (fr) 2017-05-31
US20170306026A1 (en) 2017-10-26
AU2003213231A1 (en) 2003-09-09
PL372306A1 (en) 2005-07-11
EP1485127B1 (fr) 2011-06-08
IL163725A (en) 2013-07-31
DK1485127T3 (da) 2011-10-03
MY157727A (en) 2016-07-15
NZ579583A (en) 2011-04-29
AU2009201587A1 (en) 2009-05-14
IL203515A (en) 2015-10-29
KR20040105740A (ko) 2004-12-16
CA2477178A1 (fr) 2003-09-04
NO336235B1 (no) 2015-06-22
US20110064729A1 (en) 2011-03-17
EP2289941A2 (fr) 2011-03-02
US20040009169A1 (en) 2004-01-15
IL163725A0 (en) 2005-12-18
WO2003072040A2 (fr) 2003-09-04
TWI346558B (en) 2011-08-11
EP2360185A2 (fr) 2011-08-24
EP1485127A2 (fr) 2004-12-15
DK2336184T3 (en) 2015-02-16
CO5611176A2 (es) 2006-02-28
RU2004128454A (ru) 2005-05-10
PT2336184E (pt) 2015-03-09
JP2015042629A (ja) 2015-03-05
AU2009201587B2 (en) 2012-01-19
EP2360185A3 (fr) 2012-01-11
CN1310678C (zh) 2007-04-18
JP2005526045A (ja) 2005-09-02
PL215263B1 (pl) 2013-11-29
EP2289941A3 (fr) 2012-01-18
US20150152182A1 (en) 2015-06-04
EP2336184A2 (fr) 2011-06-22
SI2336184T1 (sl) 2015-04-30
US20220162321A1 (en) 2022-05-26
TW201125584A (en) 2011-08-01

Similar Documents

Publication Publication Date Title
HK1073997A1 (en) Administration of agents for the treatment of inflammation
IL196301A0 (en) Medicament for the treatment of hapatitis c
GB0201850D0 (en) Therapeutic treatment
GB0216321D0 (en) Therapeutic treatment
GB0206876D0 (en) Therapeutic agents
GB0209991D0 (en) Therapeutic agents
IL166217A0 (en) Combination of drugs for the treatment of neoplasms
GB0209997D0 (en) Therapeutic agents
GB0209995D0 (en) Therapeutic agents
GB0210127D0 (en) Therapeutic agents
GB0210124D0 (en) Therapeutic agents
GB0223349D0 (en) Therapeutic agents
ZA200707934B (en) Thereapeutic formulations for the treatment of beta-amyloid related diseases
AU2003300791A1 (en) Combination therapy for the treatment of pain
HK1078784A1 (en) Therapeutic treatment
GB0223367D0 (en) Therapeutic treatment
GB0213869D0 (en) The treatment of pain
AU2003251875A1 (en) Combination therapy for the treatment of neoplasms
IL162818A0 (en) Combination therapy for the treatment of bacterialinfections
GB0218876D0 (en) Therapeutic agents
PL397022A1 (pl) Środek leczniczy
GB0210464D0 (en) Therapeutic treatment
GB0226462D0 (en) Therapeutic agents
GB0225501D0 (en) Therapeutic agents
GB0217068D0 (en) Therapeutic agents

Legal Events

Date Code Title Description
PE Patent expired

Effective date: 20230224