HK1071134A1 - Piperidine derivatives as potassium channel blockers - Google Patents

Piperidine derivatives as potassium channel blockers

Info

Publication number
HK1071134A1
HK1071134A1 HK05103887A HK05103887A HK1071134A1 HK 1071134 A1 HK1071134 A1 HK 1071134A1 HK 05103887 A HK05103887 A HK 05103887A HK 05103887 A HK05103887 A HK 05103887A HK 1071134 A1 HK1071134 A1 HK 1071134A1
Authority
HK
Hong Kong
Prior art keywords
channel blockers
potassium channel
piperidine derivatives
formula
therapy
Prior art date
Application number
HK05103887A
Other languages
English (en)
Inventor
Tomas Eriksson
Ghazi Noori
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of HK1071134A1 publication Critical patent/HK1071134A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK05103887A 2001-12-14 2005-05-09 Piperidine derivatives as potassium channel blockers HK1071134A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0104251A SE0104251D0 (sv) 2001-12-14 2001-12-14 Novel compounds
PCT/SE2002/002304 WO2003051839A1 (en) 2001-12-14 2002-12-11 Novel compounds

Publications (1)

Publication Number Publication Date
HK1071134A1 true HK1071134A1 (en) 2005-07-08

Family

ID=20286353

Family Applications (1)

Application Number Title Priority Date Filing Date
HK05103887A HK1071134A1 (en) 2001-12-14 2005-05-09 Piperidine derivatives as potassium channel blockers

Country Status (14)

Country Link
EP (1) EP1499590B8 (es)
AT (1) ATE325095T1 (es)
AU (1) AU2002359122A1 (es)
CA (1) CA2487365C (es)
CY (1) CY1106132T1 (es)
DE (1) DE60211223T2 (es)
DK (1) DK1499590T3 (es)
ES (1) ES2261773T3 (es)
HK (1) HK1071134A1 (es)
MY (1) MY128924A (es)
PT (1) PT1499590E (es)
SE (1) SE0104251D0 (es)
TW (1) TWI255185B (es)
WO (1) WO2003051839A1 (es)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR028948A1 (es) 2000-06-20 2003-05-28 Astrazeneca Ab Compuestos novedosos
US8796436B2 (en) 2003-04-17 2014-08-05 Alnylam Pharmaceuticals, Inc. Modified iRNA agents
US8017762B2 (en) 2003-04-17 2011-09-13 Alnylam Pharmaceuticals, Inc. Modified iRNA agents
US7723509B2 (en) 2003-04-17 2010-05-25 Alnylam Pharmaceuticals IRNA agents with biocleavable tethers
JP4597976B2 (ja) 2003-04-17 2010-12-15 アルナイラム ファーマシューティカルズ インコーポレイテッド 修飾ｉＲＮＡ剤
US7851615B2 (en) 2003-04-17 2010-12-14 Alnylam Pharmaceuticals, Inc. Lipophilic conjugated iRNA agents
CA2617127A1 (en) * 2005-08-01 2007-02-08 Astrazeneca Ab Novel piperidine derivatives as chemokine receptor modulators useful for the treatment of respiratory diseases.
TW200738635A (en) * 2005-08-02 2007-10-16 Astrazeneca Ab New salt
TW200738634A (en) 2005-08-02 2007-10-16 Astrazeneca Ab New salt
TW200734305A (en) * 2005-08-02 2007-09-16 Astrazeneca Ab New salt III
TW200744612A (en) * 2005-08-26 2007-12-16 Astrazeneca Ab New combination
WO2007024183A1 (en) * 2005-08-26 2007-03-01 Astrazeneca Ab A combination of compounds, which can be used in the treatment of respiratory diseases, especially chronic obstructive pulmonary disease (copd) and asthma
ES2340604T3 (es) 2005-12-21 2010-06-07 F. Hoffmann-La Roche Ag Lineas celulares estables que expresan herg.
US20080064884A1 (en) * 2006-05-10 2008-03-13 Astrazeneca Ab Novel Process 1
GB0702456D0 (en) 2007-02-08 2007-03-21 Astrazeneca Ab New combination
WO2008103125A1 (en) * 2007-02-23 2008-08-28 Astrazeneca Ab Novel combination of compounds to be used in the treatment of airway diseases, especially chronic obstructive pulmonary disease (copd) and asthma
WO2008121065A1 (en) * 2007-03-30 2008-10-09 Astrazeneca Ab Novel pyrrolidine derivatives as antagonists of the chemokine receptor
WO2009082343A1 (en) 2007-12-20 2009-07-02 Astrazeneca Ab Dispenser and method for entraining powder in an airflow 537
CN102176940B (zh) 2008-10-08 2014-10-01 阿斯利康(瑞典)有限公司 具有与盖移动相关的索引的吸入器
TW201036957A (en) 2009-02-20 2010-10-16 Astrazeneca Ab Novel salt 628
WO2011002406A1 (en) 2009-07-01 2011-01-06 Astrazeneca Ab Dispenser and method for entraining powder in an airflow
GB0913345D0 (en) 2009-07-31 2009-09-16 Astrazeneca Ab New combination 802
WO2011061527A1 (en) 2009-11-17 2011-05-26 Astrazeneca Ab Combinations comprising a glucocorticoid receptor modulator for the treatment of respiratory diseases
WO2011073662A1 (en) 2009-12-17 2011-06-23 Astrazeneca Ab Combination of a benzoxazinone and a further agent for treating respiratory diseases
NZ601454A (en) 2010-02-10 2014-06-27 Astrazeneca Uk Ltd Process for providing a filled canister for an inhaler
MX2013000687A (es) 2010-07-21 2013-01-29 Astrazeneca Ab Inhalador.
IN2013MN00222A (es) 2010-07-21 2015-05-29 Astrazeneca Ab
GB201021979D0 (en) 2010-12-23 2011-02-02 Astrazeneca Ab New compound
GB201021992D0 (en) 2010-12-23 2011-02-02 Astrazeneca Ab Compound
WO2012163848A1 (en) 2011-05-27 2012-12-06 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for the treatment of crohn's disease
GB201115874D0 (en) 2011-09-14 2011-10-26 Astrazeneca Ab Inhaler
GB201115870D0 (en) 2011-09-14 2011-10-26 Astrazeneca Ab Inhaler

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CO5300399A1 (es) * 2000-02-25 2003-07-31 Astrazeneca Ab Heterocicliocs que contienen nitrogeno, proceso para su preparacion y composiciones farmaceuticas que los contienen

Also Published As

Publication number Publication date
CY1106132T1 (el) 2011-06-08
TWI255185B (en) 2006-05-21
PT1499590E (pt) 2006-08-31
MY128924A (en) 2007-02-28
AU2002359122A1 (en) 2003-06-30
ATE325095T1 (de) 2006-06-15
TW200409631A (en) 2004-06-16
ES2261773T3 (es) 2006-11-16
EP1499590B8 (en) 2006-08-02
DE60211223T2 (de) 2007-04-19
CA2487365C (en) 2009-06-16
CA2487365A1 (en) 2003-06-26
EP1499590B1 (en) 2006-05-03
SE0104251D0 (sv) 2001-12-14
EP1499590A1 (en) 2005-01-26
DE60211223D1 (de) 2006-06-08
WO2003051839A1 (en) 2003-06-26
DK1499590T3 (da) 2006-07-31

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20121211