HK1068949A1 - Cross-reactive monoclonal and polyclonal antibodies which recognize surface proteins from coagulase-negative staphylococci and staphylococcus aureus - Google Patents

Cross-reactive monoclonal and polyclonal antibodies which recognize surface proteins from coagulase-negative staphylococci and staphylococcus aureus

Info

Publication number
HK1068949A1
HK1068949A1 HK05100802A HK05100802A HK1068949A1 HK 1068949 A1 HK1068949 A1 HK 1068949A1 HK 05100802 A HK05100802 A HK 05100802A HK 05100802 A HK05100802 A HK 05100802A HK 1068949 A1 HK1068949 A1 HK 1068949A1
Authority
HK
Hong Kong
Prior art keywords
coagulase
cross
staphylococcus aureus
polyclonal antibodies
surface proteins
Prior art date
Application number
HK05100802A
Other languages
English (en)
Inventor
Foster Timothy
Roche Fiona
Patti Joseph
Hutchins Jeff
Speziale Pietro
Pallen Mark
Original Assignee
Inhibitex Inc
Trinity College Dublin
Univ Pavia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inhibitex Inc, Trinity College Dublin, Univ Pavia filed Critical Inhibitex Inc
Publication of HK1068949A1 publication Critical patent/HK1068949A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1271Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Micrococcaceae (F), e.g. Staphylococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HK05100802A 2001-06-15 2005-01-31 Cross-reactive monoclonal and polyclonal antibodies which recognize surface proteins from coagulase-negative staphylococci and staphylococcus aureus HK1068949A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29809801P 2001-06-15 2001-06-15
PCT/US2002/019220 WO2002102829A2 (en) 2001-06-15 2002-06-17 Cross-reactive monoclonal and polyclonal antibodies which recognize surface proteins from coagulase-negative staphylococci and staphylococcus aureus

Publications (1)

Publication Number Publication Date
HK1068949A1 true HK1068949A1 (en) 2005-05-06

Family

ID=23149018

Family Applications (1)

Application Number Title Priority Date Filing Date
HK05100802A HK1068949A1 (en) 2001-06-15 2005-01-31 Cross-reactive monoclonal and polyclonal antibodies which recognize surface proteins from coagulase-negative staphylococci and staphylococcus aureus

Country Status (9)

Country Link
US (3) US6841154B2 (xx)
EP (3) EP2339344A1 (xx)
JP (2) JP4424984B2 (xx)
CN (1) CN100359327C (xx)
AU (2) AU2002322127B2 (xx)
CA (1) CA2450939C (xx)
HK (1) HK1068949A1 (xx)
MX (1) MXPA03011701A (xx)
WO (1) WO2002102829A2 (xx)

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US9181329B2 (en) 2007-08-31 2015-11-10 The University Of Chicago Methods and compositions related to immunizing against Staphylococcal lung diseases and conditions
CA2716706C (en) 2008-03-03 2014-02-18 Irm Llc Compounds and compositions as tlr activity modulators
US8758765B2 (en) 2008-07-29 2014-06-24 The University Of Chicago Compositions and methods related to Staphylococcal bacterium proteins
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AU2010271116B2 (en) 2009-04-03 2015-08-13 University Of Chicago Compositions and methods related to Protein A (SpA) variants
US9517263B2 (en) 2009-06-10 2016-12-13 Glaxosmithkline Biologicals Sa Benzonaphthyridine-containing vaccines
SI2445522T1 (sl) 2009-06-22 2017-10-30 Wyeth Llc Imunogeni sestavki antigenov Staphylococcusa aureusa
JO3257B1 (ar) 2009-09-02 2018-09-16 Novartis Ag مركبات وتركيبات كمعدلات لفاعلية tlr
BR112012004806B8 (pt) 2009-09-02 2022-10-04 Novartis Ag composições imunogênicas que incluem moduladores da atividade de tlr, método para aumento da eficácia da referida composição e uso
WO2011057148A1 (en) 2009-11-05 2011-05-12 Irm Llc Compounds and compositions as tlr-7 activity modulators
SG10201501980SA (en) 2009-12-15 2015-05-28 Novartis Ag Homogeneous suspension of immunopotentiating compounds and uses thereof
JP5848748B2 (ja) 2010-03-23 2016-01-27 アイアールエム・リミテッド・ライアビリティ・カンパニーIrm,Llc 感染症、炎症、呼吸器疾患などの処置に使用するtlr2アゴニストとしての化合物(システインベースのリポペプチド)および組成物
CN102268444B (zh) * 2010-06-03 2015-05-13 中国人民解放军军事医学科学院生物工程研究所 金黄色葡萄球菌截短SasA蛋白在大肠杆菌中的表达及应用
ES2655701T3 (es) 2010-07-02 2018-02-21 The University Of Chicago Composiciones y métodos relacionados con variantes de la proteína A (SpA)
US9192661B2 (en) 2010-07-06 2015-11-24 Novartis Ag Delivery of self-replicating RNA using biodegradable polymer particles
CA2819120C (en) 2010-12-22 2016-07-05 Wyeth Llc Stable immunogenic compositions of staphylococcus aureus antigens
CN102649817A (zh) * 2011-02-24 2012-08-29 复旦大学 一种抑制细菌生物膜形成的单克隆抗体
US8945588B2 (en) 2011-05-06 2015-02-03 The University Of Chicago Methods and compositions involving protective staphylococcal antigens, such as EBH polypeptides
CA2899787A1 (en) 2013-02-01 2014-08-07 Glaxosmithkline Biologicals Sa Intradermal delivery of immunological compositions comprising toll-like receptor agonists
CN104098693B (zh) * 2014-07-15 2017-05-17 中国人民解放军军事医学科学院生物工程研究所 抗金黄色葡萄球菌SasA抗原的单克隆抗体及其应用
WO2016095832A1 (en) * 2014-12-18 2016-06-23 The University Of Hong Kong Immunotherapeutic targets against staphylococcus aureus
US11446371B2 (en) 2015-11-05 2022-09-20 The Texas A&M University System Targeting of ligand binding sites in ClfA
US10738338B2 (en) 2016-10-18 2020-08-11 The Research Foundation for the State University Method and composition for biocatalytic protein-oligonucleotide conjugation and protein-oligonucleotide conjugate
MX2020008417A (es) 2018-02-12 2020-11-11 Inimmune Corp Ligandos de receptores de tipo toll.
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Also Published As

Publication number Publication date
EP2339344A1 (en) 2011-06-29
JP2010047581A (ja) 2010-03-04
EP1423701A4 (en) 2006-03-29
MXPA03011701A (es) 2004-12-06
CA2450939A1 (en) 2002-12-27
EP1423701A2 (en) 2004-06-02
WO2002102829A2 (en) 2002-12-27
US20090202578A1 (en) 2009-08-13
US6841154B2 (en) 2005-01-11
JP4424984B2 (ja) 2010-03-03
WO2002102829A3 (en) 2004-03-25
AU2008249159A1 (en) 2008-12-11
AU2008249159B2 (en) 2011-04-14
CA2450939C (en) 2012-11-06
EP2320233A1 (en) 2011-05-11
AU2002322127B2 (en) 2008-08-21
CN1543569A (zh) 2004-11-03
JP2004534080A (ja) 2004-11-11
US20050106648A1 (en) 2005-05-19
US7968100B2 (en) 2011-06-28
EP1423701B1 (en) 2012-07-25
CN100359327C (zh) 2008-01-02
US20030185833A1 (en) 2003-10-02

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Legal Events

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PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20130617