HK1066547A1 - Derivatives of 5-(pyridin-3-yl)-1-azabicyclo (3.2.1) ocatane, the preparation thereof and the application of same in therapeutics - Google Patents

Derivatives of 5-(pyridin-3-yl)-1-azabicyclo (3.2.1) ocatane, the preparation thereof and the application of same in therapeutics

Info

Publication number
HK1066547A1
HK1066547A1 HK04109549A HK04109549A HK1066547A1 HK 1066547 A1 HK1066547 A1 HK 1066547A1 HK 04109549 A HK04109549 A HK 04109549A HK 04109549 A HK04109549 A HK 04109549A HK 1066547 A1 HK1066547 A1 HK 1066547A1
Authority
HK
Hong Kong
Prior art keywords
ocatane
azabicyclo
pyridin
therapeutics
derivatives
Prior art date
Application number
HK04109549A
Other languages
English (en)
Inventor
Frederic Galli
Odile Leclerc
Alistair Lochead
Alain Nedelec
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of HK1066547A1 publication Critical patent/HK1066547A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HK04109549A 2002-01-07 2004-12-02 Derivatives of 5-(pyridin-3-yl)-1-azabicyclo (3.2.1) ocatane, the preparation thereof and the application of same in therapeutics HK1066547A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0200109A FR2834511B1 (fr) 2002-01-07 2002-01-07 Derives de 5-(pyridin-3-yl)-1-azabicyclo[3.2.1]octane, leur preparation et leur application en therapeutique
PCT/FR2003/000004 WO2003057697A1 (fr) 2002-01-07 2003-01-03 Derives de 5-(pyridin-3-yl)-1-azabicyclo [3.2.1] octane, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
HK1066547A1 true HK1066547A1 (en) 2005-03-24

Family

ID=8871176

Family Applications (1)

Application Number Title Priority Date Filing Date
HK04109549A HK1066547A1 (en) 2002-01-07 2004-12-02 Derivatives of 5-(pyridin-3-yl)-1-azabicyclo (3.2.1) ocatane, the preparation thereof and the application of same in therapeutics

Country Status (36)

Country Link
US (2) US7223750B2 (zh)
EP (1) EP1465893B1 (zh)
JP (1) JP4402957B2 (zh)
KR (1) KR100977332B1 (zh)
CN (2) CN1911928A (zh)
AR (2) AR038098A1 (zh)
AT (1) ATE355290T1 (zh)
AU (1) AU2003216777B2 (zh)
BR (1) BR0306707A (zh)
CA (1) CA2471628C (zh)
CO (1) CO5590914A2 (zh)
CY (1) CY1106580T1 (zh)
DE (1) DE60312123T2 (zh)
DK (1) DK1465893T3 (zh)
EA (1) EA007793B1 (zh)
EC (1) ECSP045176A (zh)
ES (1) ES2281631T3 (zh)
FR (1) FR2834511B1 (zh)
HK (1) HK1066547A1 (zh)
HR (1) HRP20040617B1 (zh)
IL (2) IL162524A0 (zh)
IS (1) IS2470B (zh)
MA (1) MA27165A1 (zh)
ME (2) ME00213B (zh)
MX (1) MXPA04006630A (zh)
NO (1) NO329309B1 (zh)
NZ (1) NZ533793A (zh)
PL (1) PL216665B1 (zh)
PT (1) PT1465893E (zh)
RS (1) RS50921B (zh)
SI (1) SI1465893T1 (zh)
TN (1) TNSN04120A1 (zh)
TW (1) TWI336703B (zh)
UA (1) UA77229C2 (zh)
WO (1) WO2003057697A1 (zh)
ZA (1) ZA200405002B (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9902007D0 (en) * 1999-01-30 1999-03-17 Thomas Carpentry Services Limi Improvements relating to door frames
FR2834511B1 (fr) * 2002-01-07 2004-02-13 Sanofi Synthelabo Derives de 5-(pyridin-3-yl)-1-azabicyclo[3.2.1]octane, leur preparation et leur application en therapeutique
FR2889701B1 (fr) * 2005-08-12 2007-10-05 Sanofi Aventis Sa Derives de 5-pyridinyl-1-azabicyclo[3.2.1]octane, leur preparation en therapeutique.
FR2889847B1 (fr) * 2005-08-18 2007-10-05 Sanofi Aventis Sa Derives de 5-pyridazinyl-1-azabicyclo[3.2.1]octave, leur preparation en therapeutique.
FR2912404B1 (fr) * 2007-02-09 2009-04-10 Sanofi Aventis Sa Derives d'azabicycloalkane,leur preparation et leur application en therapeutique.
KR101928505B1 (ko) 2011-01-28 2018-12-12 에스케이바이오팜 주식회사 피리돈 유도체 및 이를 포함하는 약학적 조성물
KR101925971B1 (ko) * 2011-01-28 2018-12-06 에스케이바이오팜 주식회사 피리돈 유도체 및 이를 포함하는 약학적 조성물
JP7065180B2 (ja) 2017-11-03 2022-05-11 アルコン インク． 眼疾患を治療するためのアザビシクロ及びジアゼピン誘導体

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5817679A (en) * 1993-04-01 1998-10-06 University Of Virginia 7-Azabicyclo 2.2.1!-heptane and -heptene derivatives as cholinergic receptor ligands
WO1995003306A1 (en) 1993-07-22 1995-02-02 E.I. Du Pont De Nemours And Company Arthropodicidal azacyclic heterocycles
FR2786770B1 (fr) * 1998-12-04 2001-01-19 Synthelabo Derives de 1,4-diazabicyclo[3.2.2.]nonane, leur preparation et leur application en therapeutique
FR2786769B1 (fr) * 1998-12-04 2002-10-25 Synthelabo Derives de 2,5-diazabicyclo[2.2.1]heptane, leur preparation et leur application en therapeutique
FR2834511B1 (fr) * 2002-01-07 2004-02-13 Sanofi Synthelabo Derives de 5-(pyridin-3-yl)-1-azabicyclo[3.2.1]octane, leur preparation et leur application en therapeutique

Also Published As

Publication number Publication date
EA200400770A1 (ru) 2004-12-30
CN1276921C (zh) 2006-09-27
PL216665B1 (pl) 2014-04-30
AU2003216777B2 (en) 2008-10-02
ECSP045176A (es) 2004-08-27
PL370065A1 (en) 2005-05-16
KR20040077705A (ko) 2004-09-06
RS59904A (en) 2006-10-27
ME00213B (me) 2011-02-10
TW200305413A (en) 2003-11-01
FR2834511B1 (fr) 2004-02-13
CN1911928A (zh) 2007-02-14
CA2471628C (en) 2011-03-22
US20050020568A1 (en) 2005-01-27
IS2470B (is) 2008-12-15
CA2471628A1 (en) 2003-07-17
JP4402957B2 (ja) 2010-01-20
PT1465893E (pt) 2007-05-31
AR086573A2 (es) 2014-01-08
BR0306707A (pt) 2005-02-09
FR2834511A1 (fr) 2003-07-11
CO5590914A2 (es) 2005-12-30
KR100977332B1 (ko) 2010-08-20
TNSN04120A1 (fr) 2006-06-01
HRP20040617A2 (en) 2004-10-31
ES2281631T3 (es) 2007-10-01
JP2005514422A (ja) 2005-05-19
US20070185137A1 (en) 2007-08-09
CY1106580T1 (el) 2012-01-25
NZ533793A (en) 2007-01-26
TWI336703B (en) 2011-02-01
MEP24408A (en) 2010-10-10
ZA200405002B (en) 2006-05-31
NO329309B1 (no) 2010-09-27
MXPA04006630A (es) 2004-11-10
NO20042846L (no) 2004-09-21
DE60312123T2 (de) 2007-09-13
SI1465893T1 (sl) 2007-08-31
IS7322A (is) 2004-06-16
DK1465893T3 (da) 2007-06-04
AU2003216777A1 (en) 2003-07-24
RS50921B (sr) 2010-08-31
CN1612876A (zh) 2005-05-04
EA007793B1 (ru) 2007-02-27
HRP20040617B1 (hr) 2012-10-31
MA27165A1 (fr) 2005-01-03
AR038098A1 (es) 2004-12-29
UA77229C2 (uk) 2006-11-15
IL162524A (en) 2010-05-17
US7585974B2 (en) 2009-09-08
US7223750B2 (en) 2007-05-29
DE60312123D1 (de) 2007-04-12
IL162524A0 (en) 2005-11-20
ATE355290T1 (de) 2006-03-15
EP1465893B1 (fr) 2007-02-28
EP1465893A1 (fr) 2004-10-13
WO2003057697A1 (fr) 2003-07-17

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Legal Events

Date Code Title Description
CHPA Change of a particular in the register (except of change of ownership)
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20180103