HK1063623A1 - Hydroxyeicosatetraenoic acid analogs and methods of their uwe in treating dry eye disorders. - Google Patents

Hydroxyeicosatetraenoic acid analogs and methods of their uwe in treating dry eye disorders.

Info

Publication number
HK1063623A1
HK1063623A1 HK04106324A HK04106324A HK1063623A1 HK 1063623 A1 HK1063623 A1 HK 1063623A1 HK 04106324 A HK04106324 A HK 04106324A HK 04106324 A HK04106324 A HK 04106324A HK 1063623 A1 HK1063623 A1 HK 1063623A1
Authority
HK
Hong Kong
Prior art keywords
uwe
methods
dry eye
acid analogs
eye disorders
Prior art date
Application number
HK04106324A
Other languages
English (en)
Inventor
John R Falck
Raymond E Conrow
Mark R Hellberg
Peter G Klimko
Original Assignee
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Inc filed Critical Alcon Inc
Publication of HK1063623A1 publication Critical patent/HK1063623A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/655—Azo (—N=N—), diazo (=N2), azoxy (>N—O—N< or N(=O)—N<), azido (—N3) or diazoamino (—N=N—N<) compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/46—Unsaturated compounds containing hydroxy or O-metal groups containing rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK04106324A 1999-11-09 2002-10-05 Hydroxyeicosatetraenoic acid analogs and methods of their uwe in treating dry eye disorders. HK1063623A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US16438699P 1999-11-09 1999-11-09
US16436999P 1999-11-09 1999-11-09
US16437199P 1999-11-09 1999-11-09
HK02107320.4A HK1045983B (zh) 1999-11-09 2002-10-05 羥基二十碳四烯酸類似物及其用於治療乾眼病症的方法

Publications (1)

Publication Number Publication Date
HK1063623A1 true HK1063623A1 (en) 2005-01-07

Family

ID=27389011

Family Applications (2)

Application Number Title Priority Date Filing Date
HK04106324A HK1063623A1 (en) 1999-11-09 2002-10-05 Hydroxyeicosatetraenoic acid analogs and methods of their uwe in treating dry eye disorders.
HK02107320.4A HK1045983B (zh) 1999-11-09 2002-10-05 羥基二十碳四烯酸類似物及其用於治療乾眼病症的方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK02107320.4A HK1045983B (zh) 1999-11-09 2002-10-05 羥基二十碳四烯酸類似物及其用於治療乾眼病症的方法

Country Status (18)

Country Link
EP (1) EP1228029B1 (de)
JP (1) JP4663193B2 (de)
KR (1) KR100781354B1 (de)
CN (1) CN1390191A (de)
AR (1) AR029769A1 (de)
AT (2) ATE287866T1 (de)
AU (1) AU776254B2 (de)
BR (1) BR0015424A (de)
CA (1) CA2386627C (de)
DE (2) DE60017810T2 (de)
DK (1) DK1228029T3 (de)
ES (2) ES2220559T3 (de)
HK (2) HK1063623A1 (de)
MX (1) MXPA02004704A (de)
PL (1) PL202040B1 (de)
PT (2) PT1228029E (de)
TW (1) TWI281395B (de)
WO (1) WO2001034551A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003030894A1 (en) * 2001-10-11 2003-04-17 Alcon, Inc. Methods for treating dry eye
US8710252B2 (en) * 2006-04-19 2014-04-29 Cecil Pace-Asciak Hepodxilin analog enantiomers

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4906467A (en) 1988-03-24 1990-03-06 New York Medical College Novel, long-duration treatment for glaucoma
US5696166A (en) * 1995-10-31 1997-12-09 Yanni; John M. Compositions containing hydroxyeicosatetraenoic acid derivatives and methods of use in treating dry eye disorders

Also Published As

Publication number Publication date
ES2220559T3 (es) 2004-12-16
ES2233921T3 (es) 2005-06-16
JP4663193B2 (ja) 2011-03-30
AR029769A1 (es) 2003-07-16
HK1045983A1 (en) 2002-12-20
MXPA02004704A (es) 2004-09-10
PT1228029E (pt) 2004-10-29
PL202040B1 (pl) 2009-05-29
DE60017810D1 (de) 2005-03-03
CA2386627C (en) 2008-12-23
JP2003528042A (ja) 2003-09-24
CA2386627A1 (en) 2001-05-17
PT1418167E (pt) 2005-05-31
AU776254B2 (en) 2004-09-02
ATE287866T1 (de) 2005-02-15
ATE271534T1 (de) 2004-08-15
BR0015424A (pt) 2002-07-16
CN1390191A (zh) 2003-01-08
EP1228029B1 (de) 2004-07-21
AU1226201A (en) 2001-06-06
DE60017810T2 (de) 2005-08-25
DK1228029T3 (da) 2004-10-25
PL356105A1 (en) 2004-06-14
KR100781354B1 (ko) 2007-11-30
HK1045983B (zh) 2004-12-24
EP1228029A1 (de) 2002-08-07
WO2001034551A1 (en) 2001-05-17
KR20020040849A (ko) 2002-05-30
DE60012358D1 (de) 2004-08-26
DE60012358T2 (de) 2005-02-17
TWI281395B (en) 2007-05-21

Similar Documents

Publication Publication Date Title
HK1045986A1 (en) Compositions containing hydroxyeicosatetraenoic acid derivatives and methods of use in treating dry eye disorders.
HRP20000201B1 (en) Prostaglandin agonists and their use to treat bone disorders
HUP0400914A3 (en) Methods of treatment of mitochondrial disorders
AU3920900A (en) Compounds and methods to treat cardiac failure and other disorders
NO20004098L (no) FremgangsmÕter og preparater for behandling av makrofag- formidlede lidelser
WO2001028494A3 (en) Nordihydroguaiaretic derivatives for use in treatment of tumors
PL356093A1 (en) Hydroxyeicosatetraenoate salts, compositions and methods of use in treating dry eye disorders
HUP0003298A3 (en) Branched chain fatty acids, their derivatives and use in the treatment of central nervous system disorders
GB0514417D0 (en) Methods and devices for therapeutic treatment cardiac and other pathologies
AU9527001A (en) Treatment of T cell disorders
HUP0600526A2 (en) Use of derivatives of valproic acid and 2-valproenic acid amides for the treatment of mania in bipolar disorder
HK1057332A1 (en) Use of 3-benzoylphenylacetic acid derivatives for the treatment of retinal disorders
HK1063623A1 (en) Hydroxyeicosatetraenoic acid analogs and methods of their uwe in treating dry eye disorders.
PL356127A1 (en) Omega chain modified 15-hydroxyeicosatetraenoic acid derivatives and methods of their use for the treatment of dry eye
NO990019L (no) Anvendelse av T-BAM (CD40L) ved behandling av sykdommer i glatt muskulatur
EP1150669A4 (de) Formulierungen auf l-argininbasis zur krankheitsbehandlung und deren verwendungsmethoden
WO2001034550A3 (en) 15-hydroxyeicosatetraenoic acid analogs with enhanced metabolic stability and methods of their use in treating dry eye disorders
PL351554A1 (en) Osanetant in the treatment of mood disorders
IL139731A0 (en) N-acetyl 3-chloropocainamide, acid addition salts thereof, and methods of use
HK1025894A1 (en) Hydroxamic acid derivatives as inhibitors of the production of human cd23 and of the tnf release.
EP1418167A3 (de) Hydroxyeicosatetraensäureanaloge und Verfahren deren Verwendung zur Behandlung des trockenen Auges
MXPA00012560A (es) Uso de interleucocina-11 para tratar desordenes gastrointestinales.
IL141501A0 (en) Alginate capsules for use in the treatment of brain tumour
NO955325D0 (no) Propansyrederivater, deres fremstilling og terapeutiske anvendelse
EP1517912A4 (de) Verfahren und zusammensetzungen zur behandlung von schmerzen und schmerzhaften störungen mit 577, 20739 oder 57145

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20171023