HK1063188A1 - Peptide for the diagnosis and therapy of alzeimer's disease - Google Patents

Peptide for the diagnosis and therapy of alzeimer's disease

Info

Publication number
HK1063188A1
HK1063188A1 HK04105028A HK04105028A HK1063188A1 HK 1063188 A1 HK1063188 A1 HK 1063188A1 HK 04105028 A HK04105028 A HK 04105028A HK 04105028 A HK04105028 A HK 04105028A HK 1063188 A1 HK1063188 A1 HK 1063188A1
Authority
HK
Hong Kong
Prior art keywords
diagnosis
therapy
disease
peptide
alzeimer
Prior art date
Application number
HK04105028A
Other languages
English (en)
Inventor
Dieter Willbold
Katja Wiesehan
Original Assignee
Leibniz Inst Fur Altersforschu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leibniz Inst Fur Altersforschu filed Critical Leibniz Inst Fur Altersforschu
Publication of HK1063188A1 publication Critical patent/HK1063188A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hospice & Palliative Care (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
HK04105028A 2001-04-06 2004-07-09 Peptide for the diagnosis and therapy of alzeimer's disease HK1063188A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10117281A DE10117281A1 (de) 2001-04-06 2001-04-06 Peptid zur Diagnose und Therapie der Alzheimer-Demenz
PCT/EP2002/003862 WO2002081505A2 (de) 2001-04-06 2002-04-08 Peptid zur diagnose und therapie der alzheimer-demenz

Publications (1)

Publication Number Publication Date
HK1063188A1 true HK1063188A1 (en) 2004-12-17

Family

ID=7680694

Family Applications (1)

Application Number Title Priority Date Filing Date
HK04105028A HK1063188A1 (en) 2001-04-06 2004-07-09 Peptide for the diagnosis and therapy of alzeimer's disease

Country Status (6)

Country Link
EP (1) EP1379546B1 (xx)
AT (1) ATE364623T1 (xx)
DE (2) DE10117281A1 (xx)
ES (1) ES2289110T3 (xx)
HK (1) HK1063188A1 (xx)
WO (1) WO2002081505A2 (xx)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030108539A1 (en) * 2000-02-14 2003-06-12 Christophe Bonny Cell-permeable peptide inhibitors of the JNK signal transduction pathway
US8183339B1 (en) 1999-10-12 2012-05-22 Xigen S.A. Cell-permeable peptide inhibitors of the JNK signal transduction pathway
US20040082509A1 (en) 1999-10-12 2004-04-29 Christophe Bonny Cell-permeable peptide inhibitors of the JNK signal transduction pathway
US7803749B2 (en) * 2002-01-09 2010-09-28 Xigen Sa Peptide inhibitors of MKK7 kinase binding to insulin binding proteins
DE10303974A1 (de) 2003-01-31 2004-08-05 Abbott Gmbh & Co. Kg Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung
US8080517B2 (en) 2005-09-12 2011-12-20 Xigen Sa Cell-permeable peptide inhibitors of the JNK signal transduction pathway
WO2007031098A1 (en) 2005-09-12 2007-03-22 Xigen S.A. Cell-permeable peptide inhibitors of the jnk signal transduction pathway
PL1954718T3 (pl) 2005-11-30 2015-04-30 Abbvie Inc Przeciwciała skierowane przeciwko A globulomerowi, ich reszty wiążące antygeny, odpowiednie hybrydomy, kwasy nukleinowe, wektory, komórki gospodarze, sposoby wytwarzania tych przeciwciał, kompozycje zawierające te przeciwciała, zastosowania tych przeciwciał i sposoby stosowania tych przeciwciał
DK1976877T4 (en) 2005-11-30 2017-01-16 Abbvie Inc Monoclonal antibodies to amyloid beta protein and uses thereof
US8455626B2 (en) 2006-11-30 2013-06-04 Abbott Laboratories Aβ conformer selective anti-aβ globulomer monoclonal antibodies
US20100311767A1 (en) 2007-02-27 2010-12-09 Abbott Gmbh & Co. Kg Method for the treatment of amyloidoses
WO2009143865A1 (en) 2008-05-30 2009-12-03 Xigen S.A. Use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases
WO2009143864A1 (en) 2008-05-30 2009-12-03 Xigen S.A. Use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of chronic or non-chronic inflammatory digestive diseases
DE102008037564A1 (de) * 2008-11-19 2010-05-20 Forschungszentrum Jülich GmbH Zusammensetzung zur Herstellung von anti-Amyloid beta-Peptid-Antikörpern mit D-Peptiden
WO2010072228A1 (en) 2008-12-22 2010-07-01 Xigen S.A. Novel transporter constructs and transporter cargo conjugate molecules
JP2013523182A (ja) 2010-04-15 2013-06-17 アボット・ラボラトリーズ アミロイドベータ結合タンパク質
DE102010019336A1 (de) 2010-05-05 2011-11-10 Forschungszentrum Jülich GmbH Mittel zur Behandlung der Alzheimerschen Demenz
DE102010017130B4 (de) 2010-05-28 2018-11-29 Forschungszentrum Jülich GmbH Hybrid-Verbindung, deren Verwendung und Verfahren zu deren Herstellung
WO2011160653A1 (en) 2010-06-21 2011-12-29 Xigen S.A. Novel jnk inhibitor molecules
EP2603524A1 (en) 2010-08-14 2013-06-19 AbbVie Inc. Amyloid-beta binding proteins
JP5857056B2 (ja) 2010-10-14 2016-02-10 ザイジェン インフラメーション エルティーディー 慢性又は非慢性の炎症性眼疾患を治療するためのｊｎｋシグナル伝達経路の細胞透過性ペプチド阻害剤の使用
WO2013091670A1 (en) 2011-12-21 2013-06-27 Xigen S.A. Novel jnk inhibitor molecules for treatment of various diseases
DE102012102999A1 (de) * 2012-04-05 2013-10-10 Forschungszentrum Jülich GmbH Verfahren zur Behandlung von Blut, Blutprodukten und Organen
DE102012108599B4 (de) 2012-09-14 2023-06-01 Priavoid Gmbh A-Beta-Oligomer-bindende Peptide und deren Verwendung
DE102012108598A1 (de) 2012-09-14 2014-04-10 Forschungszentrum Jülich GmbH Neue, von D3 abgeleitete D-enantiomere Peptide und deren Verwendung
DE102012102998B4 (de) 2012-04-05 2013-12-05 Forschungszentrum Jülich GmbH Polymere, enthaltend multivalente Amyloid-Beta-bindende D-Peptide und deren Verwendung
US9591845B2 (en) * 2012-04-05 2017-03-14 Forschungszentrum Juelich Gmbh Method for treating blood, blood products and organs
CN104380111B (zh) 2012-04-05 2017-08-29 于利希研究中心有限公司 包含多价结合淀粉样β蛋白的D‑肽的聚合物及其应用
DE102012019882A1 (de) 2012-10-05 2014-04-10 Forschungszentrum Jülich GmbH Peptide zur Behandlung und Frühdiagnose von Morbus Alzheimer und anderer Tauopathien
DE102012022013A1 (de) 2012-11-02 2014-05-08 Forschungszentrum Jülich GmbH Fachbereich Patente Peptide, die an amino-terminal verkürztes Amyloid-beta-Peptid binden und deren Verwendung
DE102014003262A1 (de) 2014-03-12 2015-09-17 Forschungszentrum Jülich GmbH Amyloid-Beta-bindende Peptide und deren Verwendung für die Therapie und die Diagnose der Alzheimerschen Demenz
DE102013016002A1 (de) * 2013-09-26 2015-03-26 Forschungszentrum Jülich GmbH Zyklische, Amyloid-Beta-bindende Peptide und deren Verwendung
US10030056B2 (en) * 2013-04-30 2018-07-24 Forschungszentrum Juelich Gmbh Agents for preventing and treating HIV and other viral infections
DE102013007405A1 (de) * 2013-04-30 2014-11-13 Forschungszentrum Jülich GmbH Agenzien zur Prävention und Therapie von HIV und anderer viraler Infektionen
CN105307670A (zh) 2013-06-26 2016-02-03 埃克西金炎症有限公司 Jnk信号转导途径的细胞渗透肽抑制剂用于治疗多种疾病的新用途
WO2014206427A1 (en) 2013-06-26 2014-12-31 Xigen Inflammation Ltd. New use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases
WO2015197097A1 (en) 2014-06-26 2015-12-30 Xigen Inflammation Ltd. New use for jnk inhibitor molecules for treatment of various diseases
JP6660877B2 (ja) 2013-09-26 2020-03-11 フォルシュングスツェントルム・ユーリッヒ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング アミロイド−β−結合性ペプチド、ならびにアルツハイマー型認知症の治療および診断のためのその使用
DE102015003503A1 (de) 2015-03-20 2016-09-22 Forschungszentrum Jülich GmbH Spezifisch Amyloid-Beta bindende Peptide und deren Verwendung für die Therapie und Diagnose der Alzheimerschen Demenz
DE102015003676A1 (de) * 2015-03-20 2016-09-22 Forschungszentrum Jülich GmbH Fachbereich Patente Spezifisch A-Beta Spezies bindende Peptide für die Therapie und/oder die Diagnose der Alzheimerschen Demenz
DE102016125645A1 (de) * 2016-12-23 2018-06-28 Forschungszentrum Jülich GmbH D-enantiomere Peptide zur Therapie von chronischem und neuropathischem Schmerz

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5985242A (en) * 1995-10-27 1999-11-16 Praecis Pharmaceuticals, Inc. Modulators of β-amyloid peptide aggregation comprising D-amino acids
US6420110B1 (en) * 1998-10-19 2002-07-16 Gpc Biotech, Inc. Methods and reagents for isolating biologically active peptides
JP2002543043A (ja) * 1999-03-04 2002-12-17 プラエシス ファーマシューティカルズ インコーポレーテッド Ｄ型アミノ酸を含む、ベータアミロイドペプチドの凝集のモジュレータ
CA2388092A1 (en) * 1999-05-05 2000-11-16 Neurochem, Inc. Stereoselective antifibrillogenic peptides and peptidomimetics thereof
GB9917725D0 (en) * 1999-07-28 1999-09-29 Medical Res Council Peptides

Also Published As

Publication number Publication date
ES2289110T3 (es) 2008-02-01
WO2002081505A2 (de) 2002-10-17
DE50210317D1 (de) 2007-07-26
EP1379546A2 (de) 2004-01-14
EP1379546B1 (de) 2007-06-13
ATE364623T1 (de) 2007-07-15
DE10117281A1 (de) 2002-10-24
WO2002081505A3 (de) 2003-10-23

Similar Documents

Publication Publication Date Title
HK1063188A1 (en) Peptide for the diagnosis and therapy of alzeimer's disease
WO2002046222A3 (en) Compositions and methods for diagnosing alzheimer's disease
HK1145692A1 (zh) 人血管生成素- 的特異結合劑
BG105853A (en) Kit for radiolabeling proteins with yttrium-90
IL203894A (en) Use of a polypeptide to prepare a drug to induce angiogenesis or liver regeneration
WO2003102020A3 (en) Carbon nanotube binding peptides
EP1777234A3 (en) Methods of treatment of inflammatory diseases using specific binding agents of human angiopoietin - 2
EP2360259A3 (en) Promyostatin peptides and methods of using same
WO2005018424A3 (en) Antibodies specific for fibrillar amyloid and a procedure to detect fibrillar amyloid deposits
MXPA02011656A (es) Moleculas de acido nucleico nrg-2, polipeptidos, y metodos de diagnostico y terapeuticos.
WO2000078344A8 (en) Prion protein peptides and uses thereof
CA2268029A1 (en) Therapeutic and diagnostic applications of laminin and laminin-derived protein fragments
EP1071443A4 (en) ISOLATED PEPTIDES CORRESPOND THE NY-ESO-1 AMINO ACID SEQUENCES AND BIND TO MHC CLASS I AND MHC CLASS II MOLECULES AND THEIR USE
GEP20043386B (en) β -Amyloid Peptide-Binding Proteins and Polynucleotides Encoding the Same
WO2001007479A3 (en) Fragments of cellular prion protein and methods useful in the diagnosis and treatment of prion diseases
CA2210871A1 (en) Human dnase i variants
WO2003033675A3 (en) Identification of binding partners for specific proteins
AU2003286530A1 (en) Substituted peptides useful in the treatment of alzheimer's disease
AU2003218756A1 (en) Repressor of skeletal muscle differentiation, nucleic acids coding therefor and the use thereof in diagnosis and therapy
WO2001077148A3 (en) Human lipid binding protein 1
AU2002312797A1 (en) Peptide for the diagnosis and therapy of alzheimer's disease
TW200635950A (en) Specific binding agents of human angiopoietin-2
WO2002062955A3 (en) Dendritic enriched secreted lymphocyte activation molecule
MX9706429A (es) Variantes de dnasa i humana.
AU2002314193A1 (en) Identification of ses-1 and the uses of the same

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20130408