HK1059737A1 - Method to prepare microparticles containing metroprolol. - Google Patents
Method to prepare microparticles containing metroprolol.Info
- Publication number
- HK1059737A1 HK1059737A1 HK04102597A HK04102597A HK1059737A1 HK 1059737 A1 HK1059737 A1 HK 1059737A1 HK 04102597 A HK04102597 A HK 04102597A HK 04102597 A HK04102597 A HK 04102597A HK 1059737 A1 HK1059737 A1 HK 1059737A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- metroprolol
- microparticles containing
- prepare microparticles
- metoprolol
- prepare
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0100824A SE0100824D0 (sv) | 2001-03-09 | 2001-03-09 | Method III to obtain microparticles |
PCT/SE2002/000401 WO2002072074A1 (en) | 2001-03-09 | 2002-03-06 | Method to prepare microparticles metoprolol that contain |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1059737A1 true HK1059737A1 (en) | 2004-07-16 |
Family
ID=20283295
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK04102597A HK1059737A1 (en) | 2001-03-09 | 2004-04-14 | Method to prepare microparticles containing metroprolol. |
Country Status (25)
Country | Link |
---|---|
US (1) | US20040116392A1 (de) |
EP (1) | EP1370245B1 (de) |
JP (1) | JP2004522798A (de) |
KR (1) | KR20030081507A (de) |
CN (1) | CN1236761C (de) |
AT (1) | ATE295153T1 (de) |
AU (1) | AU2002235102B2 (de) |
BR (1) | BR0207919A (de) |
CA (1) | CA2440167A1 (de) |
DE (1) | DE60204125T2 (de) |
ES (1) | ES2240691T3 (de) |
HK (1) | HK1059737A1 (de) |
HU (1) | HUP0303450A2 (de) |
IL (1) | IL157777A0 (de) |
IS (1) | IS6937A (de) |
MX (1) | MXPA03008088A (de) |
NO (1) | NO20033967L (de) |
NZ (1) | NZ528168A (de) |
PL (1) | PL363972A1 (de) |
PT (1) | PT1370245E (de) |
RU (1) | RU2292878C2 (de) |
SE (1) | SE0100824D0 (de) |
UA (1) | UA75909C2 (de) |
WO (1) | WO2002072074A1 (de) |
ZA (1) | ZA200306880B (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE0100823D0 (sv) * | 2001-03-09 | 2001-03-09 | Astrazeneca Ab | Method I to obtain microparticles |
US20060159756A1 (en) * | 1999-09-10 | 2006-07-20 | Brita Sjoblom | Method to obtain microparticles containing an H+,K+-ATP-ASE inhibitor |
SE0100822D0 (sv) * | 2001-03-09 | 2001-03-09 | Astrazeneca Ab | Method II to obtain microparticles |
US8006685B2 (en) * | 2002-07-05 | 2011-08-30 | Turbochef Technologies, Inc. | Re-circulating oven with gas clean-up |
US11311490B2 (en) | 2005-08-10 | 2022-04-26 | Add Advanced Drug Delivery Technologies Ltd. | Oral preparation with controlled release |
US20070053983A1 (en) * | 2005-09-06 | 2007-03-08 | Girish Jain | Extended release compositions of metoprolol succinate |
WO2008012346A1 (en) * | 2006-07-28 | 2008-01-31 | Farmaprojects, S. A. | Extended release pharmaceutical formulation of metoprolol and process for its preparation |
US20110014295A1 (en) * | 2007-02-23 | 2011-01-20 | Glatt Air Techniques, Inc. | Method of determining the weight of the coating to be applied to form a controlled release dosage form |
CN101269056B (zh) * | 2007-03-19 | 2010-05-19 | 天津药物研究院 | 一种美托洛尔盐类口服脉冲微丸制剂 |
US20100055180A1 (en) * | 2007-10-10 | 2010-03-04 | Mallinckrodt Baker, Inc. | Directly Compressible Granular Microcrystalline Cellulose Based Excipient, Manufacturing Process and Use Thereof |
NZ584521A (en) * | 2007-10-10 | 2011-03-31 | Avantor Performance Mat Inc | Directly compressible high functionality granular microcrystalline cellulose based excipient, manufacturing process and use thereof |
CN102641257A (zh) * | 2012-03-31 | 2012-08-22 | 内蒙古医学院 | 阿替洛尔缓释微囊及其制备方法 |
RU2585023C1 (ru) * | 2014-12-18 | 2016-05-27 | Общество с ограниченной ответственностью "Нанолек" | Способ гранулирования |
CN104739805B (zh) * | 2015-04-09 | 2017-12-19 | 邸蓉 | 制备琥珀酸美托洛尔缓释微丸的复相乳液法 |
US10744087B2 (en) | 2018-03-22 | 2020-08-18 | Incarda Therapeutics, Inc. | Method to slow ventricular rate |
CN115252913A (zh) * | 2022-08-02 | 2022-11-01 | 赛诺神畅医疗科技有限公司 | 一种血管给药涂层及其制备方法和应用 |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US653014A (en) * | 1899-10-06 | 1900-07-03 | Ashley & Bailey Company | Process of silkifying cotton. |
SE354851B (de) * | 1970-02-18 | 1973-03-26 | Haessle Ab | |
DE3565475D1 (en) * | 1984-04-07 | 1988-11-17 | Bayer Ag | Process and apparatus for the production of granules |
IE58110B1 (en) * | 1984-10-30 | 1993-07-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
SE450087B (sv) * | 1985-10-11 | 1987-06-09 | Haessle Ab | Korn med kontrollerad frisettning av farmaceutiskt aktiva emnen som anbringats teckande pa ett kompakt olosligt kernmaterial |
SE455836B (sv) * | 1985-10-11 | 1988-08-15 | Haessle Ab | Beredning med kontrollerad frisettning innehallande ett salt av metoprolol samt metod for framstellning av denna beredning |
DE3909455A1 (de) * | 1989-03-22 | 1990-09-27 | Hoechst Ag | Verfahren zur herstellung von wasserdispergierbaren granulaten |
FR2725623A1 (fr) * | 1994-10-18 | 1996-04-19 | Flamel Tech Sa | Microcapsules medicamenteuses et/ou nutritionnelles pour administration per os |
DE69617245T2 (de) * | 1995-08-17 | 2002-07-25 | Csir, Pretoria | Produkte mit gesteuerter freisetzung |
DE19613395A1 (de) * | 1996-04-03 | 1997-10-09 | Basf Ag | Granulate hygroskopischer, wasserlöslicher Produkte |
US6096339A (en) * | 1997-04-04 | 2000-08-01 | Alza Corporation | Dosage form, process of making and using same |
US5891474A (en) * | 1997-01-29 | 1999-04-06 | Poli Industria Chimica, S.P.A. | Time-specific controlled release dosage formulations and method of preparing same |
DE19733094A1 (de) * | 1997-07-31 | 1999-02-04 | Merck Patent Gmbh | Formulierung auf der Basis von Ascorbinsäure mit verbesserter Farbstabilität |
CN1154510C (zh) * | 1997-10-15 | 2004-06-23 | 默克专利股份有限公司 | 直压制片助剂的生产方法 |
EP0987020A1 (de) * | 1998-09-04 | 2000-03-22 | Pharma Pass LLC | Zusammensetzung enthaltend Metoprolol und Verfahren zur Herstellung |
US6395300B1 (en) * | 1999-05-27 | 2002-05-28 | Acusphere, Inc. | Porous drug matrices and methods of manufacture thereof |
US20060159756A1 (en) * | 1999-09-10 | 2006-07-20 | Brita Sjoblom | Method to obtain microparticles containing an H+,K+-ATP-ASE inhibitor |
SE0100823D0 (sv) * | 2001-03-09 | 2001-03-09 | Astrazeneca Ab | Method I to obtain microparticles |
ES2372746T3 (es) * | 2000-09-20 | 2012-01-26 | Jagotec Ag | Micropartículas de fibrato estabilizadas. |
SE0100822D0 (sv) * | 2001-03-09 | 2001-03-09 | Astrazeneca Ab | Method II to obtain microparticles |
-
2001
- 2001-03-09 SE SE0100824A patent/SE0100824D0/xx unknown
-
2002
- 2002-03-06 MX MXPA03008088A patent/MXPA03008088A/es active IP Right Grant
- 2002-03-06 AT AT02701873T patent/ATE295153T1/de not_active IP Right Cessation
- 2002-03-06 KR KR10-2003-7011782A patent/KR20030081507A/ko active IP Right Grant
- 2002-03-06 EP EP02701873A patent/EP1370245B1/de not_active Expired - Lifetime
- 2002-03-06 CN CNB028095901A patent/CN1236761C/zh not_active Expired - Fee Related
- 2002-03-06 ES ES02701873T patent/ES2240691T3/es not_active Expired - Lifetime
- 2002-03-06 DE DE60204125T patent/DE60204125T2/de not_active Expired - Fee Related
- 2002-03-06 HU HU0303450A patent/HUP0303450A2/hu unknown
- 2002-03-06 PL PL02363972A patent/PL363972A1/xx not_active Application Discontinuation
- 2002-03-06 PT PT02701873T patent/PT1370245E/pt unknown
- 2002-03-06 AU AU2002235102A patent/AU2002235102B2/en not_active Ceased
- 2002-03-06 IL IL15777702A patent/IL157777A0/xx unknown
- 2002-03-06 CA CA002440167A patent/CA2440167A1/en not_active Abandoned
- 2002-03-06 WO PCT/SE2002/000401 patent/WO2002072074A1/en active IP Right Grant
- 2002-03-06 BR BR0207919-4A patent/BR0207919A/pt not_active IP Right Cessation
- 2002-03-06 NZ NZ528168A patent/NZ528168A/en unknown
- 2002-03-06 RU RU2003127739/15A patent/RU2292878C2/ru not_active IP Right Cessation
- 2002-03-06 JP JP2002571033A patent/JP2004522798A/ja active Pending
- 2002-03-06 US US10/469,907 patent/US20040116392A1/en not_active Abandoned
- 2002-06-03 UA UA2003098380A patent/UA75909C2/uk unknown
-
2003
- 2003-09-03 ZA ZA200306880A patent/ZA200306880B/en unknown
- 2003-09-03 IS IS6937A patent/IS6937A/is unknown
- 2003-09-08 NO NO20033967A patent/NO20033967L/no not_active Application Discontinuation
-
2004
- 2004-04-14 HK HK04102597A patent/HK1059737A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
HUP0303450A2 (hu) | 2004-01-28 |
NO20033967L (no) | 2003-10-28 |
CN1507345A (zh) | 2004-06-23 |
CN1236761C (zh) | 2006-01-18 |
MXPA03008088A (es) | 2003-12-12 |
NZ528168A (en) | 2005-01-28 |
EP1370245B1 (de) | 2005-05-11 |
CA2440167A1 (en) | 2002-09-19 |
US20040116392A1 (en) | 2004-06-17 |
NO20033967D0 (no) | 2003-09-08 |
DE60204125T2 (de) | 2006-01-19 |
BR0207919A (pt) | 2004-04-27 |
PT1370245E (pt) | 2005-08-31 |
ES2240691T3 (es) | 2005-10-16 |
UA75909C2 (en) | 2006-06-15 |
KR20030081507A (ko) | 2003-10-17 |
JP2004522798A (ja) | 2004-07-29 |
ZA200306880B (en) | 2004-12-03 |
SE0100824D0 (sv) | 2001-03-09 |
ATE295153T1 (de) | 2005-05-15 |
PL363972A1 (en) | 2004-11-29 |
RU2292878C2 (ru) | 2007-02-10 |
AU2002235102B2 (en) | 2006-08-31 |
IL157777A0 (en) | 2004-03-28 |
EP1370245A1 (de) | 2003-12-17 |
WO2002072074A1 (en) | 2002-09-19 |
DE60204125D1 (de) | 2005-06-16 |
RU2003127739A (ru) | 2005-03-10 |
IS6937A (is) | 2003-09-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1059737A1 (en) | Method to prepare microparticles containing metroprolol. | |
HUT65374A (en) | Process for producing of dialkylene-piperidino compounds,their enantiomers and pharmaceutical compositions comprising them | |
MY111556A (en) | Substituted azadioxacycloalkenes. | |
IL103282A0 (en) | Substituted 4-alkoxypyrimidines,process for their preparation,compositions containing them,and their use as pesticides | |
BG103740A (en) | Phytostyrene composition for the prevention of the alzheimer's disease | |
HUT59106A (en) | Process for producing 3-amidopyrazoles and pharmaceutical compositions comprising such compounds as active ingredient | |
HUT60430A (en) | Process for producing medical aerosol compositions | |
EP0372466A3 (de) | 2-Amino-4- oder 5-Methoxycyclohexylamide, verwendbar als Analgetica | |
MY136231A (en) | Slow release compositions | |
MX9602442A (es) | Un tratamiento con fluoroquinolona a dosis unica elevada. | |
MXPA03007887A (es) | Metodo para obtener microparticulas que contienen inhibidor de h(+), k(+)-atp-asa. | |
MY137846A (en) | Processes for the preparation of oral dosage formulations of modafinil | |
GB0029774D0 (en) | Clay composition | |
HU9801925D0 (en) | Sodium-hydrogen-change-inhibitors for producing pharmaceutical compositions for treating diseases caused by protozoons | |
EP1640019A4 (de) | Feinkörnige zubereitung des humanen wachstumshormons mti verzögerter freisetzung und herstellungsverfahren dafür | |
EP1206524A4 (de) | Verfahren zur herstellung von doppelt haploiden pflanzen | |
EP0382251A3 (de) | Adamantyl enthaltende Tripeptide, deren Derivate und Hydrochloride, deren Herstellung und Benutzung | |
GB9702081D0 (en) | Process for preparing colloidal calcium carbonte by particle sizer | |
IL104156A0 (en) | Fungicidal compositions containing certain compounds,their agricultural use and methods for producing said compounds | |
HUT55604A (en) | Fungicide and growth-controlling compositions containing n-oxo-azolyl-methyl-oxiranes as active components and process for producing the active components | |
MX9705908A (es) | Particulas de arilpirrol estables, el proceso para su preparacion y las composiciones de concentrado en suspension que las comprenden. | |
MY129110A (en) | Polysaccharide compound having immune stimulating activity | |
UA38961A (uk) | Спосіб лікування розсіяного склерозу | |
HUP0402418A3 (en) | Substituted 1,5-diaminopentan-3-ol compounds, process for producing them, pharmaceutical compositions containing them and use thereof | |
EP0526793A3 (en) | Process for the preparation of diphenylamines |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20090306 |