HK1049653A1 - Transfer hydrogenation process - Google Patents
Transfer hydrogenation processInfo
- Publication number
- HK1049653A1 HK1049653A1 HK03101722A HK03101722A HK1049653A1 HK 1049653 A1 HK1049653 A1 HK 1049653A1 HK 03101722 A HK03101722 A HK 03101722A HK 03101722 A HK03101722 A HK 03101722A HK 1049653 A1 HK1049653 A1 HK 1049653A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- transfer hydrogenation
- bidentate ligands
- hydrogenation process
- iminium salts
- employed
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 5
- 238000009901 transfer hydrogenation reaction Methods 0.000 title abstract 3
- ZMANZCXQSJIPKH-UHFFFAOYSA-N Triethylamine Chemical compound CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 abstract 3
- 239000003446 ligand Substances 0.000 abstract 3
- 230000003197 catalytic effect Effects 0.000 abstract 2
- 150000002466 imines Chemical class 0.000 abstract 2
- 150000007975 iminium salts Chemical class 0.000 abstract 2
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 abstract 2
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 abstract 1
- KJTLSVCANCCWHF-UHFFFAOYSA-N Ruthenium Chemical compound [Ru] KJTLSVCANCCWHF-UHFFFAOYSA-N 0.000 abstract 1
- 150000001414 amino alcohols Chemical class 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 150000004696 coordination complex Chemical class 0.000 abstract 1
- 125000000058 cyclopentadienyl group Chemical group C1(=CC=CC1)* 0.000 abstract 1
- 150000004985 diamines Chemical class 0.000 abstract 1
- ZSWFCLXCOIISFI-UHFFFAOYSA-N endo-cyclopentadiene Natural products C1C=CC=C1 ZSWFCLXCOIISFI-UHFFFAOYSA-N 0.000 abstract 1
- 235000019253 formic acid Nutrition 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 239000000852 hydrogen donor Substances 0.000 abstract 1
- 229910052741 iridium Inorganic materials 0.000 abstract 1
- GKOZUEZYRPOHIO-UHFFFAOYSA-N iridium atom Chemical compound [Ir] GKOZUEZYRPOHIO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052751 metal Inorganic materials 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 150000002739 metals Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003141 primary amines Chemical class 0.000 abstract 1
- 229910052703 rhodium Inorganic materials 0.000 abstract 1
- 239000010948 rhodium Substances 0.000 abstract 1
- MHOVAHRLVXNVSD-UHFFFAOYSA-N rhodium atom Chemical compound [Rh] MHOVAHRLVXNVSD-UHFFFAOYSA-N 0.000 abstract 1
- 229910052707 ruthenium Inorganic materials 0.000 abstract 1
- 150000003335 secondary amines Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B43/00—Formation or introduction of functional groups containing nitrogen
- C07B43/04—Formation or introduction of functional groups containing nitrogen of amino groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B53/00—Asymmetric syntheses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/24—Preparation of compounds containing amino groups bound to a carbon skeleton by reductive alkylation of ammonia, amines or compounds having groups reducible to amino groups, with carbonyl compounds
- C07C209/26—Preparation of compounds containing amino groups bound to a carbon skeleton by reductive alkylation of ammonia, amines or compounds having groups reducible to amino groups, with carbonyl compounds by reduction with hydrogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/62—Preparation of compounds containing amino groups bound to a carbon skeleton by cleaving carbon-to-nitrogen, sulfur-to-nitrogen, or phosphorus-to-nitrogen bonds, e.g. hydrolysis of amides, N-dealkylation of amines or quaternary ammonium compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
- C07F9/36—Amides thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Catalysts (AREA)
- Production Of Liquid Hydrocarbon Mixture For Refining Petroleum (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Superconductors And Manufacturing Methods Therefor (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Seasonings (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9919118.1A GB9919118D0 (en) | 1999-08-14 | 1999-08-14 | Transfer hydrogenation process |
| PCT/GB2000/002867 WO2001012574A1 (en) | 1999-08-14 | 2000-07-25 | Transfer hydrogenation process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1049653A1 true HK1049653A1 (en) | 2003-05-23 |
Family
ID=10859084
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK03101722A HK1049653A1 (en) | 1999-08-14 | 2003-03-10 | Transfer hydrogenation process |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US6696608B1 (ko) |
| EP (1) | EP1210305B1 (ko) |
| JP (1) | JP2003507353A (ko) |
| KR (1) | KR100787946B1 (ko) |
| CN (1) | CN1328230C (ko) |
| AT (1) | ATE299846T1 (ko) |
| AU (1) | AU779493B2 (ko) |
| CA (1) | CA2383266A1 (ko) |
| CZ (1) | CZ2002535A3 (ko) |
| DE (1) | DE60021394T2 (ko) |
| DK (1) | DK1210305T3 (ko) |
| ES (1) | ES2246246T3 (ko) |
| GB (1) | GB9919118D0 (ko) |
| HK (1) | HK1049653A1 (ko) |
| HU (1) | HUP0202493A3 (ko) |
| IL (2) | IL147673A0 (ko) |
| MX (1) | MXPA02001499A (ko) |
| NO (1) | NO20020734L (ko) |
| PT (1) | PT1210305E (ko) |
| WO (1) | WO2001012574A1 (ko) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6743921B2 (en) | 2002-01-24 | 2004-06-01 | Dsm Catalytica Pharmaceuticals, Inc. | Process for the preparation of nonracemic syn-1-(4-hydroxy-phenyl)-2-(4-hydroxy-4-phenyl-piperidin-1-yl)-1-propanol compounds |
| GB0424004D0 (en) * | 2004-10-29 | 2004-12-01 | Avecia Ltd | Process |
| US8133717B2 (en) | 2006-12-22 | 2012-03-13 | Richmond Chemical Corporation | Stereoinversion of amino acids in a single reactor |
| US8519029B2 (en) * | 2008-06-16 | 2013-08-27 | Construction Research & Technology Gmbh | Copolymer admixture system for workability retention of cementitious compositions |
| CN102076634A (zh) * | 2008-06-27 | 2011-05-25 | 默克弗罗斯特加拿大有限公司 | 手性胺的合成 |
| CN101845056B (zh) * | 2010-03-05 | 2012-08-29 | 中国科学院上海有机化学研究所 | 一类c1对称的手性二烯配体、合成方法及其在不对称反应中的应用 |
| WO2017033134A1 (en) | 2015-08-26 | 2017-03-02 | Lupin Limited | Enzymatic process for the for preparation of (r)-1-(1-naphthyl) ethylamine, an intermediate of cinacalcet hydrochloride |
| CN111448299B (zh) * | 2017-10-17 | 2023-10-31 | 丝趣科尔卡有限公司 | 气味剂和包含气味剂的组合物 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2900804B2 (ja) * | 1994-10-18 | 1999-06-02 | 日本鋼管株式会社 | プラグ耐用度に優れた継目無鋼管の製造方法 |
| DE69833365T2 (de) * | 1997-03-06 | 2006-09-28 | Mitsui Chemicals, Inc. | Verfahren zur herstellung optisch aktiver amine |
| GB9706321D0 (en) | 1997-03-26 | 1997-05-14 | Zeneca Ltd | Catalytic hydrogenation |
-
1999
- 1999-08-14 GB GBGB9919118.1A patent/GB9919118D0/en not_active Ceased
-
2000
- 2000-07-25 CA CA002383266A patent/CA2383266A1/en not_active Abandoned
- 2000-07-25 HU HU0202493A patent/HUP0202493A3/hu unknown
- 2000-07-25 DK DK00949706T patent/DK1210305T3/da active
- 2000-07-25 CN CNB008115346A patent/CN1328230C/zh not_active Expired - Fee Related
- 2000-07-25 WO PCT/GB2000/002867 patent/WO2001012574A1/en active IP Right Grant
- 2000-07-25 JP JP2001516876A patent/JP2003507353A/ja not_active Withdrawn
- 2000-07-25 IL IL14767300A patent/IL147673A0/xx active IP Right Grant
- 2000-07-25 AU AU62982/00A patent/AU779493B2/en not_active Ceased
- 2000-07-25 US US10/049,611 patent/US6696608B1/en not_active Expired - Fee Related
- 2000-07-25 ES ES00949706T patent/ES2246246T3/es not_active Expired - Lifetime
- 2000-07-25 DE DE60021394T patent/DE60021394T2/de not_active Expired - Fee Related
- 2000-07-25 PT PT00949706T patent/PT1210305E/pt unknown
- 2000-07-25 MX MXPA02001499A patent/MXPA02001499A/es active IP Right Grant
- 2000-07-25 CZ CZ2002535A patent/CZ2002535A3/cs unknown
- 2000-07-25 EP EP00949706A patent/EP1210305B1/en not_active Expired - Lifetime
- 2000-07-25 KR KR1020027001663A patent/KR100787946B1/ko not_active IP Right Cessation
- 2000-07-25 AT AT00949706T patent/ATE299846T1/de not_active IP Right Cessation
-
2002
- 2002-01-16 IL IL147673A patent/IL147673A/en not_active IP Right Cessation
- 2002-02-13 NO NO20020734A patent/NO20020734L/no not_active Application Discontinuation
-
2003
- 2003-03-10 HK HK03101722A patent/HK1049653A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CN1368945A (zh) | 2002-09-11 |
| US6696608B1 (en) | 2004-02-24 |
| HUP0202493A3 (en) | 2003-11-28 |
| DE60021394D1 (de) | 2005-08-25 |
| ATE299846T1 (de) | 2005-08-15 |
| KR100787946B1 (ko) | 2007-12-24 |
| AU6298200A (en) | 2001-03-13 |
| CN1328230C (zh) | 2007-07-25 |
| HUP0202493A2 (hu) | 2002-11-28 |
| PT1210305E (pt) | 2005-11-30 |
| EP1210305B1 (en) | 2005-07-20 |
| KR20020026253A (ko) | 2002-04-06 |
| IL147673A0 (en) | 2002-08-14 |
| GB9919118D0 (en) | 1999-10-13 |
| NO20020734D0 (no) | 2002-02-13 |
| DK1210305T3 (da) | 2005-11-07 |
| ES2246246T3 (es) | 2006-02-16 |
| CZ2002535A3 (cs) | 2002-05-15 |
| JP2003507353A (ja) | 2003-02-25 |
| WO2001012574A1 (en) | 2001-02-22 |
| CA2383266A1 (en) | 2001-02-22 |
| AU779493B2 (en) | 2005-01-27 |
| NO20020734L (no) | 2002-02-13 |
| IL147673A (en) | 2007-10-31 |
| EP1210305A1 (en) | 2002-06-05 |
| MXPA02001499A (es) | 2002-10-23 |
| DE60021394T2 (de) | 2006-03-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20110725 |