HK1045959A1 - Method and device for applying a plurality of microdroplets onto a substrate. - Google Patents

Method and device for applying a plurality of microdroplets onto a substrate.

Info

Publication number
HK1045959A1
HK1045959A1 HK02107609A HK02107609A HK1045959A1 HK 1045959 A1 HK1045959 A1 HK 1045959A1 HK 02107609 A HK02107609 A HK 02107609A HK 02107609 A HK02107609 A HK 02107609A HK 1045959 A1 HK1045959 A1 HK 1045959A1
Authority
HK
Hong Kong
Prior art keywords
applying
substrate
liquid
nozzle orifices
pressure
Prior art date
Application number
HK02107609A
Other languages
English (en)
Inventor
Holger Gruhler
Nicolaus Hey
Hermann Sandmaier
Roland Zengerle
Original Assignee
Hahn Schickard Ges
Roland Zengerle
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Publication of HK1045959A1 publication Critical patent/HK1045959A1/xx
Application filed by Hahn Schickard Ges, Roland Zengerle filed Critical Hahn Schickard Ges

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0241—Drop counters; Drop formers
    • B01L3/0268—Drop counters; Drop formers using pulse dispensing or spraying, eg. inkjet type, piezo actuated ejection of droplets from capillaries
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00351—Means for dispensing and evacuation of reagents
    • B01J2219/00378—Piezoelectric or ink jet dispensers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/00527—Sheets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00659—Two-dimensional arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0481—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure squeezing of channels or chambers
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027—General features of the devices
    • G01N2035/1034—Transferring microquantities of liquid
    • G01N2035/1041—Ink-jet like dispensers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Application Of Or Painting With Fluid Materials (AREA)
  • Coating Apparatus (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Physical Deposition Of Substances That Are Components Of Semiconductor Devices (AREA)
  • Exposure Of Semiconductors, Excluding Electron Or Ion Beam Exposure (AREA)
HK02107609A 1999-09-02 2002-12-21 Method and device for applying a plurality of microdroplets onto a substrate. HK1045959A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19941871A DE19941871A1 (de) 1999-09-02 1999-09-02 Vorrichtung und Verfahren zum Aufbringen einer Mehrzahl von Mikrotröpfchen auf ein Substrat
PCT/EP2000/003173 WO2001017669A1 (de) 1999-09-02 2000-04-10 Vorrichtung und verfahren zum aufbringen einer mehrzahl von mikrotröpfchen auf ein substrat

Publications (1)

Publication Number Publication Date
HK1045959A1 true HK1045959A1 (en) 2002-12-20

Family

ID=7920578

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02107609A HK1045959A1 (en) 1999-09-02 2002-12-21 Method and device for applying a plurality of microdroplets onto a substrate.

Country Status (10)

Country Link
US (1) US7479256B1 (zh)
EP (1) EP1212133B1 (zh)
JP (1) JP3896283B2 (zh)
CN (1) CN1194817C (zh)
AT (1) ATE249274T1 (zh)
AU (1) AU755169B2 (zh)
CA (1) CA2376863C (zh)
DE (2) DE19941871A1 (zh)
HK (1) HK1045959A1 (zh)
WO (1) WO2001017669A1 (zh)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3673893B2 (ja) * 1999-10-15 2005-07-20 日本碍子株式会社 液滴吐出装置
EP1289762B1 (en) * 2000-05-24 2005-11-09 Silverbrook Research Pty. Limited Paper thickness sensor in a printer
DE10041536A1 (de) * 2000-08-24 2002-03-07 Roland Zengerle Vorrichtung und Verfahren zum berührungslosen Aufbringen von Mikrotröpfchen auf ein Substrat
DE10117064A1 (de) * 2001-04-05 2003-02-06 Morphochem Ag Vorrichtung zum automatischen Dispensieren mikroskopischer Volumina von Fluiden
DE10129243C2 (de) * 2001-06-18 2003-12-04 Fraunhofer Ges Forschung Verfahren und Vorrichtung zur Dosierung fluider Medien
DE10210469A1 (de) * 2002-03-11 2003-09-25 Axaron Bioscience Ag Aufbringen eines Stoffs auf ein Substrat
FR2868966B1 (fr) * 2004-04-19 2007-08-03 Brice Lopez Dispositif de production de micro-gouttes par ejection de liquide et procede de realisation d'un tel dispositif
US20060165895A1 (en) * 2005-01-24 2006-07-27 Julio Cartagena System and a method for synthesizing nanoparticle arrays in-situ
EP1859284A1 (de) * 2005-03-17 2007-11-28 Kuoni, A. Vorrichtung und verfahren zum aufbringen einer vielzahl von mikrotröpfchen auf ein substrat
US7740806B2 (en) * 2006-02-28 2010-06-22 International Business Machines Corporation Ceramic microarray spotting device for bioassay printing
KR100762848B1 (ko) 2006-05-25 2007-10-04 씨제이 주식회사 균류 단백질의 제조방법, 이에 의해 제조된 균류 단백질,이 균류 단백질을 포함하는 저칼로리의 인조육 및 천연육고기향 향미제
JP5050638B2 (ja) * 2007-05-11 2012-10-17 ブラザー工業株式会社 液滴吐出装置
US7922313B2 (en) * 2007-11-29 2011-04-12 Silverbrook Research Pty Ltd Printhead with pressure-dampening structures
US8011773B2 (en) * 2007-11-29 2011-09-06 Silverbrook Research Pty Ltd Printer with minimal distance between pressure-dampening structures and nozzles
US11235323B2 (en) 2008-08-27 2022-02-01 Life Technologies Corporation Apparatus for and method of processing biological samples
JP5492207B2 (ja) 2008-08-27 2014-05-14 ライフ テクノロジーズ コーポレーション 生物学的サンプルの処理装置および処理方法
DE102009018021B4 (de) 2009-04-18 2013-09-05 Helmholtz-Zentrum Berlin Für Materialien Und Energie Gmbh Mikrodosiersystem mit einem gepulsten Laser
GB2473868A (en) 2009-09-28 2011-03-30 Invitrogen Dynal As Apparatus and method of automated processing of biological samples
EP3924107A4 (en) * 2019-02-15 2022-10-05 Cellsorter Kft. PIEZOELECTRIC MICRO-PIPETTE

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JPS52110484A (en) 1976-03-12 1977-09-16 Stanley Electric Co Ltd Wiring unit for automobile and manufacturing process thereof
US4380018A (en) * 1980-06-20 1983-04-12 Sanyo Denki Kabushiki Kaisha Ink droplet projecting device and an ink jet printer
JPS59178363A (ja) 1983-03-29 1984-10-09 Shimadzu Corp 分注装置
US5508200A (en) * 1992-10-19 1996-04-16 Tiffany; Thomas Method and apparatus for conducting multiple chemical assays
EP0594110B1 (en) * 1992-10-20 2000-02-02 Canon Kabushiki Kaisha Ink jet head, method of producing the ink jet head and ink jet apparatus operable using the ink jet head
US5343909A (en) * 1992-12-17 1994-09-06 Jack Goodman Liquid transfer device
JP2721127B2 (ja) 1994-03-03 1998-03-04 富士通株式会社 インクジェットヘッド
US6015880A (en) 1994-03-16 2000-01-18 California Institute Of Technology Method and substrate for performing multiple sequential reactions on a matrix
US5585069A (en) 1994-11-10 1996-12-17 David Sarnoff Research Center, Inc. Partitioned microelectronic and fluidic device array for clinical diagnostics and chemical synthesis
JPH08219956A (ja) 1995-02-17 1996-08-30 Hitachi Koki Co Ltd ピペット及びその使用方法
US5551487A (en) * 1995-03-10 1996-09-03 Hewlett-Packard Company Micro-dispenser for preparing assay plates
JPH0976513A (ja) 1995-09-12 1997-03-25 Brother Ind Ltd インク噴射装置
EP0912892B1 (en) * 1996-05-30 2008-09-17 Cellomics, Inc. Miniaturized cell array methods and apparatus for cell-based screening
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DE19913076A1 (de) 1999-03-23 2000-10-19 Hahn Schickard Ges Vorrichtung und Verfahren zum Aufbringen von Mikrotröpfchen auf ein Substrat
DE19917029C2 (de) 1999-04-15 2001-08-09 Inst Mikrotechnik Mainz Gmbh Verfahren und Vorrichtung zur dosierten Ausgabe von Flüssigkeitsmengen im Bereich von 0,1 nl bis 100 mul
US6485690B1 (en) * 1999-05-27 2002-11-26 Orchid Biosciences, Inc. Multiple fluid sample processor and system
US6399396B1 (en) 2000-01-28 2002-06-04 Agilent Technologies, Inc. Compressed loading apparatus and method for liquid transfer

Also Published As

Publication number Publication date
CN1371302A (zh) 2002-09-25
EP1212133B1 (de) 2003-09-10
CN1194817C (zh) 2005-03-30
JP2003508767A (ja) 2003-03-04
JP3896283B2 (ja) 2007-03-22
ATE249274T1 (de) 2003-09-15
AU755169B2 (en) 2002-12-05
WO2001017669A1 (de) 2001-03-15
CA2376863A1 (en) 2001-03-15
DE50003666D1 (de) 2003-10-16
DE19941871A1 (de) 2001-04-19
EP1212133A1 (de) 2002-06-12
AU4546000A (en) 2001-04-10
US7479256B1 (en) 2009-01-20
CA2376863C (en) 2005-05-31

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20090410