HK1043054B - 用於治療蒽環類藥物意外外滲的右雷佐生 - Google Patents

用於治療蒽環類藥物意外外滲的右雷佐生

Info

Publication number
HK1043054B
HK1043054B HK02104568.2A HK02104568A HK1043054B HK 1043054 B HK1043054 B HK 1043054B HK 02104568 A HK02104568 A HK 02104568A HK 1043054 B HK1043054 B HK 1043054B
Authority
HK
Hong Kong
Prior art keywords
treatment
anthracyclines
extravasation
dexrazoxane
topoisomerase
Prior art date
Application number
HK02104568.2A
Other languages
English (en)
Other versions
HK1043054A1 (en
Inventor
W Langer Seppo
Buhl Jensen Peter
Sehested Maxwell
Original Assignee
Clinigen Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Clinigen Group Plc filed Critical Clinigen Group Plc
Publication of HK1043054A1 publication Critical patent/HK1043054A1/xx
Publication of HK1043054B publication Critical patent/HK1043054B/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Toxicology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Chemical And Physical Treatments For Wood And The Like (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
HK02104568.2A 1999-03-12 2002-06-19 用於治療蒽環類藥物意外外滲的右雷佐生 HK1043054B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA199900355 1999-03-12
PCT/DK2000/000107 WO2000054782A1 (en) 1999-03-12 2000-03-13 Treatment of accidental extravasation of anthracyclines

Publications (2)

Publication Number Publication Date
HK1043054A1 HK1043054A1 (en) 2002-09-06
HK1043054B true HK1043054B (zh) 2004-12-17

Family

ID=8092594

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02104568.2A HK1043054B (zh) 1999-03-12 2002-06-19 用於治療蒽環類藥物意外外滲的右雷佐生

Country Status (17)

Country Link
US (1) US6727253B2 (zh)
EP (2) EP1459752A3 (zh)
JP (1) JP4422916B2 (zh)
CN (1) CN1199644C (zh)
AT (1) ATE265215T1 (zh)
AU (1) AU769533B2 (zh)
BR (1) BR0009473A (zh)
CA (1) CA2367240C (zh)
DE (2) DE1162981T1 (zh)
DK (1) DK1162981T3 (zh)
ES (1) ES2220424T3 (zh)
HK (1) HK1043054B (zh)
MX (1) MXPA01009212A (zh)
NO (1) NO327354B1 (zh)
PT (1) PT1162981E (zh)
RU (1) RU2252761C2 (zh)
WO (1) WO2000054782A1 (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60209471D1 (de) * 2001-03-29 2006-04-27 Topo Target As Copenhagen Koeb Succinimid- und maleimidderivate und ihre verwendung als katalytische inhibitoren der topoisomerase ii
WO2007062076A2 (en) * 2005-11-23 2007-05-31 Novartis Ag Dexrazoxane formulations and methods
AU2015299055C1 (en) * 2014-08-06 2021-05-06 Ascendis Pharma A/S Prodrugs comprising an aminoalkyl glycine linker

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4963551A (en) * 1987-12-21 1990-10-16 Erbamont Inc. Stable lyophilized form of (S)-(+)-bis-4,4'-(1-methyl-1,2-ethanediyl)2,6-piperazinedione and solutions thereof
US5242901A (en) * 1988-01-27 1993-09-07 New York University Reduction of anthracycline induced cardiotoxicity
GB9122720D0 (en) * 1991-10-25 1991-12-11 Holthuis Josephus J M (s)(+)-4,4'-(1-methyl-1,2-ethanediyl)-bis(2,6-piperazinedione)formulations and their preparation
WO1993021938A1 (en) * 1992-05-04 1993-11-11 Adria Laboratories Methods for treating cancer using high-dose epirubicin
EP0642353A1 (en) 1992-05-14 1995-03-15 Oncologix, Inc. Treatment of vascular leakage syndrome and collagenase induced disease by administration of matrix metalloproteinase inhibitors
US5620961A (en) * 1994-04-25 1997-04-15 Markovic; Nenad S. Fructose ester-β-cyclodextrin complexes and processes for making and using same
AU1367797A (en) * 1996-01-11 1997-08-01 Peter Buhl Jensen Topoisomerase ii poison and bis-dioxypiperazine derivative combination therapy
FR2758264B1 (fr) 1997-01-16 1999-03-26 Charles Dumontet Compositions medicamenteuses contenant de l'edta ou un de ses derives pour la prevention de la toxicite cutanee et sous-cutanee des anthracyclines et de leurs derives
AU6575498A (en) 1997-03-20 1998-10-12 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Hydroxybenzoate metabolites and hydroxybenzoate analogues as protectors against oxidative stress and chemotherapeutic drug cytotoxicity, cardiotoxicity and extravasation tissue injury

Also Published As

Publication number Publication date
EP1162981B1 (en) 2004-04-28
US6727253B2 (en) 2004-04-27
DE60010241D1 (de) 2004-06-03
US20020099057A1 (en) 2002-07-25
CN1346275A (zh) 2002-04-24
CA2367240A1 (en) 2000-09-21
CA2367240C (en) 2010-11-16
MXPA01009212A (es) 2004-04-23
EP1162981A1 (en) 2001-12-19
AU769533B2 (en) 2004-01-29
JP4422916B2 (ja) 2010-03-03
NO327354B1 (no) 2009-06-15
RU2252761C2 (ru) 2005-05-27
DE60010241T2 (de) 2005-01-13
EP1459752A2 (en) 2004-09-22
WO2000054782A1 (en) 2000-09-21
ES2220424T3 (es) 2004-12-16
AU3272600A (en) 2000-10-04
HK1043054A1 (en) 2002-09-06
EP1459752A3 (en) 2007-07-18
NO20014433L (no) 2001-11-06
CN1199644C (zh) 2005-05-04
DE1162981T1 (de) 2002-05-23
NO20014433D0 (no) 2001-09-12
JP2002539168A (ja) 2002-11-19
PT1162981E (pt) 2004-09-30
DK1162981T3 (da) 2004-08-16
BR0009473A (pt) 2001-11-27
ATE265215T1 (de) 2004-05-15

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Legal Events

Date Code Title Description
AS Change of ownership

Owner name: TOPOTARGET A/S

Free format text: FORMER OWNER(S): ANTIANTHRA APS

PE Patent expired

Effective date: 20200312