HK1039059A1 - 負調節對治療蛋白的免疫應答的方法 - Google Patents

負調節對治療蛋白的免疫應答的方法

Info

Publication number
HK1039059A1
HK1039059A1 HK02100157.7A HK02100157A HK1039059A1 HK 1039059 A1 HK1039059 A1 HK 1039059A1 HK 02100157 A HK02100157 A HK 02100157A HK 1039059 A1 HK1039059 A1 HK 1039059A1
Authority
HK
Hong Kong
Prior art keywords
downmodulating
methods
immune response
therapeutic proteins
proteins
Prior art date
Application number
HK02100157.7A
Other languages
English (en)
Chinese (zh)
Inventor
Qian Jiahua
W Hoyer Leon
Collins Mary
S Gray Gary
Original Assignee
Genetics Inst Llc
American Nat Red Cross
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetics Inst Llc, American Nat Red Cross filed Critical Genetics Inst Llc
Publication of HK1039059A1 publication Critical patent/HK1039059A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
HK02100157.7A 1998-09-21 2002-01-10 負調節對治療蛋白的免疫應答的方法 HK1039059A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15817898A 1998-09-21 1998-09-21
PCT/US1999/021991 WO2000016801A1 (fr) 1998-09-21 1999-09-21 Methodes de modulation restrictive de la reponse immunitaire aux proteines therapeutiques

Publications (1)

Publication Number Publication Date
HK1039059A1 true HK1039059A1 (zh) 2002-04-12

Family

ID=22566971

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02100157.7A HK1039059A1 (zh) 1998-09-21 2002-01-10 負調節對治療蛋白的免疫應答的方法

Country Status (21)

Country Link
EP (1) EP1115423A1 (fr)
JP (1) JP2002526455A (fr)
KR (1) KR20010085830A (fr)
CN (1) CN1331602A (fr)
AU (1) AU761206B2 (fr)
BR (1) BR9913991A (fr)
CA (1) CA2343916A1 (fr)
CZ (1) CZ20011021A3 (fr)
EA (1) EA005236B1 (fr)
HK (1) HK1039059A1 (fr)
HU (1) HUP0103960A3 (fr)
IL (1) IL142069A0 (fr)
LT (1) LT4920B (fr)
LV (1) LV12768B (fr)
MX (1) MXPA01002898A (fr)
NO (1) NO20011412L (fr)
NZ (1) NZ511034A (fr)
PL (1) PL346796A1 (fr)
SI (1) SI20626A (fr)
WO (1) WO2000016801A1 (fr)
ZA (1) ZA200103156B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5397703A (en) 1992-07-09 1995-03-14 Cetus Oncology Corporation Method for generation of antibodies to cell surface molecules
EP1289552B1 (fr) * 2000-05-19 2006-03-29 The Center for Blood Research, INC. Procedes pour des troubles hemostatiques par de la p-selectine soluble
EP1636579A4 (fr) * 2003-06-10 2011-10-05 Smiths Detection Inc Ensemble detecteur
GB201508024D0 (en) 2015-05-11 2015-06-24 Haemostatix Ltd Haemostatic compositions

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5171569A (en) 1985-03-15 1992-12-15 National Research Development Corporation Factor IX preparations uncontaminated by plasma components or pox virus
CA1341174C (fr) 1985-04-12 2001-01-30 John J. Toole Jr. Proteines procoagulantes derivees du facteur viii: c
US5422260A (en) 1986-05-29 1995-06-06 Genetics Institute, Inc. -Legal Affairs Human factor VIII:c muteins
US4994371A (en) 1987-08-28 1991-02-19 Davie Earl W DNA preparation of Christmas factor and use of DNA sequences
FR2657884B1 (fr) 1990-02-05 1994-09-02 Tm Innovation Procede pour la preparation du facteur viii humain et d'analogues du facteur viii.
US5661008A (en) 1991-03-15 1997-08-26 Kabi Pharmacia Ab Recombinant human factor VIII derivatives
US5770197A (en) 1991-06-27 1998-06-23 Bristol-Myers Squibb Company Methods for regulating the immune response using B7 binding molecules and IL4-binding molecules
DE69226871T3 (de) 1991-06-27 2009-09-24 Bristol-Myers Squibb Co. CTL4A-Rezeptor, ihn enthaltenden Fusionsproteine und deren Verwendung
WO1993009804A1 (fr) 1991-11-18 1993-05-27 The Scripps Research Institute Polypeptides derives de la serine protease et anticorps anti-peptidiques, systemes et procedes therapeutiques empechant la coagulation du sang
US5663060A (en) 1992-04-07 1997-09-02 Emory University Hybrid human/animal factor VIII
US5364771A (en) 1992-04-07 1994-11-15 Emory University Hybrid human/porcine factor VIII
US5744446A (en) 1992-04-07 1998-04-28 Emory University Hybrid human/animal factor VIII
US5621039A (en) 1993-06-08 1997-04-15 Hallahan; Terrence W. Factor IX- polymeric conjugates
WO1996005860A1 (fr) * 1994-08-19 1996-02-29 Novo Nordisk A/S Methode de traitement d'un patient a l'aide d'un compose biologiquement actif
JPH10507758A (ja) * 1994-10-19 1998-07-28 ジェネティック セラピー，インコーポレイテッド アデノウイルスおよび免疫抑制剤同時反復投与を伴う遺伝子治療
US5714583A (en) 1995-06-07 1998-02-03 Genetics Institute, Inc. Factor IX purification methods
AU710998B2 (en) * 1996-03-20 1999-10-07 Bristol-Myers Squibb Company Methods for inhibiting an immune response by blocking the GP39/CD40 and CTLA4 /CD28/B7 pathways and compositions for use therewith
DE69837322T2 (de) * 1997-01-10 2007-11-22 Biogen Idec Ma Inc., Cambridge Verfahren zur therapeutischen verabreichung von anti-cd40l-mitteln
EP1034001B1 (fr) * 1997-06-20 2004-08-04 Biogen Idec MA Inc. Therapie par blocage des cellules cd154 contre le syndrome inhibiteur de proteines therapeutiques
US8112896B2 (en) 2009-11-06 2012-02-14 Hexagon Metrology Ab Articulated arm

Also Published As

Publication number Publication date
LT4920B (lt) 2002-06-25
BR9913991A (pt) 2001-07-03
IL142069A0 (en) 2002-03-10
NZ511034A (en) 2004-03-26
HUP0103960A2 (hu) 2002-02-28
WO2000016801A9 (fr) 2000-10-26
AU6057899A (en) 2000-04-10
WO2000016801A1 (fr) 2000-03-30
LT2001045A (en) 2002-01-25
MXPA01002898A (es) 2002-06-04
CA2343916A1 (fr) 2000-03-30
HUP0103960A3 (en) 2003-09-29
EA200100385A1 (ru) 2001-10-22
LV12768A (en) 2001-12-20
KR20010085830A (ko) 2001-09-07
LV12768B (lv) 2002-06-20
CZ20011021A3 (cs) 2001-10-17
JP2002526455A (ja) 2002-08-20
SI20626A (sl) 2002-02-28
PL346796A1 (en) 2002-02-25
EA005236B1 (ru) 2004-12-30
NO20011412D0 (no) 2001-03-20
CN1331602A (zh) 2002-01-16
ZA200103156B (en) 2002-07-18
AU761206B2 (en) 2003-05-29
EP1115423A1 (fr) 2001-07-18
NO20011412L (no) 2001-05-16

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