HK1036276A1 - New compounds of 9-(3,5-dimethoxyphenyl)-5,8,8a,9-tetrahydrofuro (3'm,4':6,7)naphtho(2,3-d)(1,3)dioxol-6(5ah)-one,a process for their preparation and pharmaceutical compositions containing them. - Google Patents

New compounds of 9-(3,5-dimethoxyphenyl)-5,8,8a,9-tetrahydrofuro (3'm,4':6,7)naphtho(2,3-d)(1,3)dioxol-6(5ah)-one,a process for their preparation and pharmaceutical compositions containing them.

Info

Publication number
HK1036276A1
HK1036276A1 HK01106752A HK01106752A HK1036276A1 HK 1036276 A1 HK1036276 A1 HK 1036276A1 HK 01106752 A HK01106752 A HK 01106752A HK 01106752 A HK01106752 A HK 01106752A HK 1036276 A1 HK1036276 A1 HK 1036276A1
Authority
HK
Hong Kong
Prior art keywords
alkyl
aryl
nr3r4
arylalkyl
halo
Prior art date
Application number
HK01106752A
Other languages
English (en)
Inventor
Claude Monneret
Emmanuel Bertounesque
Philippe Meresse
Ghanem Atassi
Alain Pierre
Bruno Pfeiffer
Pierre Renard
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of HK1036276A1 publication Critical patent/HK1036276A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
HK01106752A 1999-10-28 2001-09-25 New compounds of 9-(3,5-dimethoxyphenyl)-5,8,8a,9-tetrahydrofuro (3'm,4':6,7)naphtho(2,3-d)(1,3)dioxol-6(5ah)-one,a process for their preparation and pharmaceutical compositions containing them. HK1036276A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9913514A FR2800374B1 (fr) 1999-10-28 1999-10-28 Nouveaux derives de 9-(3,5-dimethoxyphenyl)-5,8,8a,9- tetrahydrofuro[3',4':6,7]naphto[2,3-d] [1,3]dioxol-6(5ah)- one, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.

Publications (1)

Publication Number Publication Date
HK1036276A1 true HK1036276A1 (en) 2001-12-28

Family

ID=9551486

Family Applications (1)

Application Number Title Priority Date Filing Date
HK01106752A HK1036276A1 (en) 1999-10-28 2001-09-25 New compounds of 9-(3,5-dimethoxyphenyl)-5,8,8a,9-tetrahydrofuro (3'm,4':6,7)naphtho(2,3-d)(1,3)dioxol-6(5ah)-one,a process for their preparation and pharmaceutical compositions containing them.

Country Status (23)

Country Link
US (1) US6281198B1 (zh)
EP (1) EP1095940B1 (zh)
JP (1) JP3426206B2 (zh)
KR (1) KR100448526B1 (zh)
CN (1) CN1155601C (zh)
AT (1) ATE271558T1 (zh)
AU (1) AU774049B2 (zh)
BR (1) BR0005123A (zh)
CA (1) CA2324495A1 (zh)
DE (1) DE60012287T2 (zh)
DK (1) DK1095940T3 (zh)
EA (1) EA004440B1 (zh)
ES (1) ES2225052T3 (zh)
FR (1) FR2800374B1 (zh)
HK (1) HK1036276A1 (zh)
HU (1) HUP0004193A3 (zh)
MX (1) MXPA00010225A (zh)
NO (1) NO20005390L (zh)
NZ (1) NZ507831A (zh)
PL (1) PL343540A1 (zh)
PT (1) PT1095940E (zh)
SI (1) SI1095940T1 (zh)
ZA (1) ZA200006078B (zh)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7176236B2 (en) * 2002-06-21 2007-02-13 University Of North Carolina At Chapel Hill Water-soluble etoposide analogs and methods of use thereof
US6566393B1 (en) 2002-06-21 2003-05-20 The University Of North Carolina At Chapel Hill Etoposide analogs and methods of use thereof
EP1599485A2 (en) * 2003-02-18 2005-11-30 Ranbaxy Laboratories, Ltd. Podophyllotoxin derivatives as antitumor agents
CN101544652B (zh) * 2009-04-29 2011-06-15 南通大学 硫脲类表鬼臼毒素化合物及其制备方法和用途
JP5892508B2 (ja) * 2011-05-23 2016-03-23 国立大学法人 鹿児島大学 抗腫瘍剤及びその製造方法
CN102875564B (zh) * 2012-09-29 2015-10-21 湖北工业大学 具抗肿瘤活性的氮取代鬼臼类衍生物及其制备方法和用途
WO2014102889A1 (ja) * 2012-12-25 2014-07-03 国立大学法人鹿児島大学 抗腫瘍剤及びその製造方法
CN103613600B (zh) * 2013-11-15 2017-01-04 湖北工业大学 具抗肿瘤活性的苯胺基鬼臼类衍生物及其制备方法和用途
JP6326966B2 (ja) * 2014-05-26 2018-05-23 ユニマテック株式会社 含フッ素ウレタン（メタ）アクリレートの製造法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE335139B (zh) * 1964-08-12 1971-05-17 Sandoz Ag
JPS61227590A (ja) * 1985-04-02 1986-10-09 Microbial Chem Res Found 新規４′−デメチル−４−エピポドフイロトキシン誘導体
US5066645A (en) * 1989-09-01 1991-11-19 Bristol-Myers Company Epipodophyllotoxin altroside derivatives
FR2739857B1 (fr) * 1995-10-12 1998-01-02 Pf Medicament Nouveaux derives amines de 2",3"-didesoxyglycosides d'epipodophyllotoxine, leur procede de preparation, leur utilisation comme medicament et leur utilisation destinee aux traitements anticancereux

Also Published As

Publication number Publication date
EP1095940A3 (fr) 2001-10-24
BR0005123A (pt) 2001-05-29
KR20010040195A (ko) 2001-05-15
PL343540A1 (en) 2001-05-07
CA2324495A1 (fr) 2001-04-28
US6281198B1 (en) 2001-08-28
MXPA00010225A (es) 2002-08-06
EA200001001A2 (ru) 2001-04-23
DE60012287D1 (de) 2004-08-26
NO20005390D0 (no) 2000-10-26
AU774049B2 (en) 2004-06-17
ES2225052T3 (es) 2005-03-16
ZA200006078B (en) 2001-05-18
ATE271558T1 (de) 2004-08-15
DK1095940T3 (da) 2004-11-22
NO20005390L (no) 2001-04-30
DE60012287T2 (de) 2005-07-21
HU0004193D0 (zh) 2001-01-29
NZ507831A (en) 2001-08-31
CN1296008A (zh) 2001-05-23
HUP0004193A2 (hu) 2001-08-28
AU6959700A (en) 2001-05-03
FR2800374B1 (fr) 2002-06-28
SI1095940T1 (en) 2004-10-31
EA200001001A3 (ru) 2001-06-25
CN1155601C (zh) 2004-06-30
EP1095940B1 (fr) 2004-07-21
JP2001131182A (ja) 2001-05-15
HUP0004193A3 (en) 2002-08-28
JP3426206B2 (ja) 2003-07-14
FR2800374A1 (fr) 2001-05-04
KR100448526B1 (ko) 2004-09-13
EP1095940A2 (fr) 2001-05-02
PT1095940E (pt) 2004-10-29
EA004440B1 (ru) 2004-04-29

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20081027