HK1031388A1 - Azole peptidomimetics as thrombin receptor antagonists - Google Patents

Azole peptidomimetics as thrombin receptor antagonists

Info

Publication number
HK1031388A1
HK1031388A1 HK01102265A HK01102265A HK1031388A1 HK 1031388 A1 HK1031388 A1 HK 1031388A1 HK 01102265 A HK01102265 A HK 01102265A HK 01102265 A HK01102265 A HK 01102265A HK 1031388 A1 HK1031388 A1 HK 1031388A1
Authority
HK
Hong Kong
Prior art keywords
receptor antagonists
thrombin receptor
azole
peptidomimetics
azole peptidomimetics
Prior art date
Application number
HK01102265A
Other languages
English (en)
Inventor
William Hoekstra
Becky L Hulshizer
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Publication of HK1031388A1 publication Critical patent/HK1031388A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK01102265A 1998-02-19 2001-03-28 Azole peptidomimetics as thrombin receptor antagonists HK1031388A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7517198P 1998-02-19 1998-02-19
PCT/US1999/002627 WO1999042475A1 (en) 1998-02-19 1999-02-08 Azole peptidomimetics as thrombin receptor antagonists

Publications (1)

Publication Number Publication Date
HK1031388A1 true HK1031388A1 (en) 2001-06-15

Family

ID=22124023

Family Applications (1)

Application Number Title Priority Date Filing Date
HK01102265A HK1031388A1 (en) 1998-02-19 2001-03-28 Azole peptidomimetics as thrombin receptor antagonists

Country Status (11)

Country Link
EP (1) EP1054892B1 (ja)
JP (1) JP2002504490A (ja)
AT (1) ATE223928T1 (ja)
AU (1) AU2590799A (ja)
CA (1) CA2321104A1 (ja)
DE (1) DE69902887T2 (ja)
DK (1) DK1054892T3 (ja)
ES (1) ES2183515T3 (ja)
HK (1) HK1031388A1 (ja)
PT (1) PT1054892E (ja)
WO (1) WO1999042475A1 (ja)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU42401A (sh) 1998-12-14 2003-12-31 Ortho-Mcneil Pharmaceuticals Inc. Supstituisani heterociklični acil-tripeptidi korisni kao modulatori receptora trombina
US6365617B1 (en) 1999-06-29 2002-04-02 Ortho-Mcneil Pharmaceutical, Inc. Indole and indazole urea-peptoids as thrombin receptor antagonists
US6630451B1 (en) 1999-06-29 2003-10-07 Orthomcneil Pharmaceutical, Inc. Benzimidazolone peptidometics as thrombin receptor antagonist
AU5895500A (en) 1999-06-29 2001-01-31 Cor Therapeutics, Inc. Novel indazole peptidomimetics as thrombin receptor antagonists
US6858577B1 (en) 1999-06-29 2005-02-22 Ortho-Mcneil Pharmaceutical, Inc. Indole peptidomimetics as thrombin receptor antagonists
US7622593B2 (en) 2006-06-27 2009-11-24 The Procter & Gamble Company Human protein tyrosine phosphatase inhibitors and methods of use
EP2982756A1 (en) * 2014-08-04 2016-02-10 Berlin Cures Holding AG Aptamers for use against autoantibody-associated diseases

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL106197A (en) * 1992-07-30 1999-11-30 Cor Therapeutics Inc Agagonists for the rhombin receptors and pharmaceutical preparations containing them
JPH07285952A (ja) * 1994-04-08 1995-10-31 Fujisawa Pharmaceut Co Ltd 新規複素環誘導体

Also Published As

Publication number Publication date
AU2590799A (en) 1999-09-06
DE69902887T2 (de) 2003-08-07
EP1054892B1 (en) 2002-09-11
DE69902887D1 (de) 2002-10-17
DK1054892T3 (da) 2003-01-20
ATE223928T1 (de) 2002-09-15
ES2183515T3 (es) 2003-03-16
JP2002504490A (ja) 2002-02-12
WO1999042475A1 (en) 1999-08-26
CA2321104A1 (en) 1999-08-26
EP1054892A1 (en) 2000-11-29
PT1054892E (pt) 2002-12-31

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20080208