MX9700373A - Derivados morfinoides de heterociclo condensado. - Google Patents

Derivados morfinoides de heterociclo condensado.

Info

Publication number
MX9700373A
MX9700373A MX9700373A MX9700373A MX9700373A MX 9700373 A MX9700373 A MX 9700373A MX 9700373 A MX9700373 A MX 9700373A MX 9700373 A MX9700373 A MX 9700373A MX 9700373 A MX9700373 A MX 9700373A
Authority
MX
Mexico
Prior art keywords
heterocycle
condensed
derivatives
morphinoid derivatives
condensed morphinoid
Prior art date
Application number
MX9700373A
Other languages
English (en)
Inventor
Giulio Dondio
Silvano Ronzoni
Original Assignee
Smithkline Beecham Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Spa filed Critical Smithkline Beecham Spa
Publication of MX9700373A publication Critical patent/MX9700373A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Transplantation (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Compuestos de formula (I) son agonistas y antagonistas opioides delta selectivos, y son utiles como analgésicos y en tratamiento de transtornos neurologicos generales.
MX9700373A 1994-07-14 1995-07-07 Derivados morfinoides de heterociclo condensado. MX9700373A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI941463A IT1270612B (it) 1994-07-14 1994-07-14 Derivati eterociclo-condensatori di morfinoidi
PCT/EP1995/002694 WO1996002545A1 (en) 1994-07-14 1995-07-07 Heterocycle-condensed morphinoid derivatives

Publications (1)

Publication Number Publication Date
MX9700373A true MX9700373A (es) 1998-03-31

Family

ID=11369271

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9700373A MX9700373A (es) 1994-07-14 1995-07-07 Derivados morfinoides de heterociclo condensado.

Country Status (19)

Country Link
US (1) US5981540A (es)
EP (1) EP0770081B1 (es)
JP (1) JP3480936B2 (es)
CN (1) CN1051086C (es)
AT (1) ATE236169T1 (es)
AU (1) AU686413B2 (es)
BR (1) BR9508406A (es)
CA (1) CA2194877A1 (es)
CZ (1) CZ9897A3 (es)
DE (1) DE69530205T2 (es)
ES (1) ES2196069T3 (es)
HU (1) HUT76812A (es)
IT (1) IT1270612B (es)
MX (1) MX9700373A (es)
NO (1) NO315119B1 (es)
NZ (1) NZ289858A (es)
PL (1) PL182747B1 (es)
WO (1) WO1996002545A1 (es)
ZA (1) ZA955782B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5985880A (en) 1996-06-05 1999-11-16 Delta Pharmaceuticals Compositions and methods for reducing respiratory depression and attendant side effects of mu opioid compounds
WO1997025331A1 (en) * 1996-01-10 1997-07-17 Smithkline Beecham S.P.A. Heterocycle-condensed morphinoid derivatives (ii)
US6103722A (en) * 1997-07-23 2000-08-15 The Medical College Of Wisconsin Research Foundation Inc. Ischemic preconditioning
IT1312083B1 (it) * 1999-04-20 2002-04-04 Smithkline Beecham Spa Derivati morfinoidi, procedimento per la loro preparazione e loroimpiego terapeutico.
EP1210084A4 (en) * 1999-08-13 2002-11-13 Southern Res Inst PYRIDOMORPHINANS, THIENOMORPHINANS AND THEIR USE
US7015326B1 (en) * 1999-08-13 2006-03-21 Southern Research Institute Pyridomorphinans, thienomorphinans and use thereof
ES2222227T3 (es) * 1999-08-13 2005-02-01 Southern Research Institute Piridomorfinanos y su utilizacion.
GB0025056D0 (en) * 2000-10-12 2000-11-29 Smithkline Beecham Spa Novel compounds
CA2538146C (en) * 2003-08-27 2013-10-22 Southern Research Institute Pyridomorphinans, pyridazinomorphinans and use thereof
CA2872469A1 (en) * 2012-05-02 2013-11-07 Southern Research Institute Heterocycle-fused morphinans, use thereof and preparation thereof
AU2013381199A1 (en) 2013-03-08 2015-10-29 Nippon Chemiphar Co., Ltd. Morphinan derivative
CA2952124A1 (en) * 2014-06-13 2015-12-17 Purdue Pharma L.P. Heterocyclic morphinan derivatives and use thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5225417A (en) * 1992-01-21 1993-07-06 G. D. Searle & Co. Opioid agonist compounds
US5223507A (en) * 1992-01-21 1993-06-29 G. D. Searle & Co. Method of using opioid compounds as delta opioid selective agonist analgesics

Also Published As

Publication number Publication date
AU686413B2 (en) 1998-02-05
ES2196069T3 (es) 2003-12-16
JPH10502657A (ja) 1998-03-10
NZ289858A (en) 1998-01-26
CN1161041A (zh) 1997-10-01
BR9508406A (pt) 1997-12-23
ITMI941463A1 (it) 1996-01-14
US5981540A (en) 1999-11-09
EP0770081B1 (en) 2003-04-02
DE69530205T2 (de) 2004-02-05
CZ9897A3 (en) 1997-07-16
ATE236169T1 (de) 2003-04-15
NO970142L (no) 1997-03-12
WO1996002545A1 (en) 1996-02-01
ITMI941463A0 (it) 1994-07-14
CA2194877A1 (en) 1996-02-01
EP0770081A1 (en) 1997-05-02
PL182747B1 (pl) 2002-02-28
AU2982495A (en) 1996-02-16
CN1051086C (zh) 2000-04-05
NO970142D0 (no) 1997-01-13
NO315119B1 (no) 2003-07-14
ZA955782B (en) 1996-02-26
HUT76812A (en) 1997-11-28
IT1270612B (it) 1997-05-07
JP3480936B2 (ja) 2003-12-22
PL318148A1 (en) 1997-05-12
HU9700073D0 (en) 1997-02-28
DE69530205D1 (de) 2003-05-08

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Legal Events

Date Code Title Description
FG Grant or registration
MM Annulment or lapse due to non-payment of fees