HK1023339A1 - Novel aminooxyamide tricyclic inhibitors of farnesylprotein transferase - Google Patents
Novel aminooxyamide tricyclic inhibitors of farnesylprotein transferaseInfo
- Publication number
- HK1023339A1 HK1023339A1 HK00102233A HK00102233A HK1023339A1 HK 1023339 A1 HK1023339 A1 HK 1023339A1 HK 00102233 A HK00102233 A HK 00102233A HK 00102233 A HK00102233 A HK 00102233A HK 1023339 A1 HK1023339 A1 HK 1023339A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- aminooxyamide
- novel
- tricyclic
- tricyclic inhibitors
- inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87705197A | 1997-06-17 | 1997-06-17 | |
| PCT/US1998/011510 WO1998057965A1 (en) | 1997-06-17 | 1998-06-15 | Novel aminooxyamide tricyclic inhibitors of farnesylprotein transferase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1023339A1 true HK1023339A1 (en) | 2000-09-08 |
Family
ID=25369148
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK00102233A HK1023339A1 (en) | 1997-06-17 | 2000-04-13 | Novel aminooxyamide tricyclic inhibitors of farnesylprotein transferase |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0991643B1 (ja) |
| JP (1) | JP2002504151A (ja) |
| CN (1) | CN1134433C (ja) |
| AT (1) | ATE236149T1 (ja) |
| AU (1) | AU8058698A (ja) |
| CA (1) | CA2293553C (ja) |
| DE (1) | DE69812945T2 (ja) |
| ES (1) | ES2196566T3 (ja) |
| HK (1) | HK1023339A1 (ja) |
| WO (1) | WO1998057965A1 (ja) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4826853A (en) * | 1986-10-31 | 1989-05-02 | Schering Corporation | 6,11-Dihydro-11-(N-substituted-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-B)pyridines and compositions and methods of use |
| IL111235A (en) * | 1993-10-15 | 2001-03-19 | Schering Plough Corp | Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them |
| US5719148A (en) * | 1993-10-15 | 1998-02-17 | Schering Corporation | Tricyclic amide and urea compounds useful for inhibition of g-protein function and for treatment of proliferative diseases |
-
1998
- 1998-06-15 AT AT98928892T patent/ATE236149T1/de not_active IP Right Cessation
- 1998-06-15 CN CNB988082233A patent/CN1134433C/zh not_active Expired - Fee Related
- 1998-06-15 WO PCT/US1998/011510 patent/WO1998057965A1/en active IP Right Grant
- 1998-06-15 DE DE69812945T patent/DE69812945T2/de not_active Expired - Lifetime
- 1998-06-15 JP JP50450499A patent/JP2002504151A/ja not_active Ceased
- 1998-06-15 CA CA002293553A patent/CA2293553C/en not_active Expired - Fee Related
- 1998-06-15 ES ES98928892T patent/ES2196566T3/es not_active Expired - Lifetime
- 1998-06-15 AU AU80586/98A patent/AU8058698A/en not_active Abandoned
- 1998-06-15 EP EP98928892A patent/EP0991643B1/en not_active Expired - Lifetime
-
2000
- 2000-04-13 HK HK00102233A patent/HK1023339A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2293553A1 (en) | 1998-12-23 |
| EP0991643A1 (en) | 2000-04-12 |
| CN1267299A (zh) | 2000-09-20 |
| ATE236149T1 (de) | 2003-04-15 |
| WO1998057965A1 (en) | 1998-12-23 |
| DE69812945D1 (de) | 2003-05-08 |
| ES2196566T3 (es) | 2003-12-16 |
| CN1134433C (zh) | 2004-01-14 |
| CA2293553C (en) | 2008-01-22 |
| EP0991643B1 (en) | 2003-04-02 |
| AU8058698A (en) | 1999-01-04 |
| JP2002504151A (ja) | 2002-02-05 |
| DE69812945T2 (de) | 2004-03-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PF | Patent in force | ||
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20070615 |