DE69812945D1 - Tricyclische aminooxyamide derivate als farnesyl protein transferase inhibitoren - Google Patents
Tricyclische aminooxyamide derivate als farnesyl protein transferase inhibitorenInfo
- Publication number
- DE69812945D1 DE69812945D1 DE69812945T DE69812945T DE69812945D1 DE 69812945 D1 DE69812945 D1 DE 69812945D1 DE 69812945 T DE69812945 T DE 69812945T DE 69812945 T DE69812945 T DE 69812945T DE 69812945 D1 DE69812945 D1 DE 69812945D1
- Authority
- DE
- Germany
- Prior art keywords
- tricyclic
- protein transferase
- farnesyl protein
- aminooxyamid
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87705197A | 1997-06-17 | 1997-06-17 | |
| US877051 | 1997-06-17 | ||
| PCT/US1998/011510 WO1998057965A1 (en) | 1997-06-17 | 1998-06-15 | Novel aminooxyamide tricyclic inhibitors of farnesylprotein transferase |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69812945D1 true DE69812945D1 (de) | 2003-05-08 |
| DE69812945T2 DE69812945T2 (de) | 2004-03-11 |
Family
ID=25369148
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69812945T Expired - Lifetime DE69812945T2 (de) | 1997-06-17 | 1998-06-15 | Tricyclische aminooxyamide derivate als farnesyl protein transferase inhibitoren |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0991643B1 (de) |
| JP (1) | JP2002504151A (de) |
| CN (1) | CN1134433C (de) |
| AT (1) | ATE236149T1 (de) |
| AU (1) | AU8058698A (de) |
| CA (1) | CA2293553C (de) |
| DE (1) | DE69812945T2 (de) |
| ES (1) | ES2196566T3 (de) |
| HK (1) | HK1023339A1 (de) |
| WO (1) | WO1998057965A1 (de) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4826853A (en) * | 1986-10-31 | 1989-05-02 | Schering Corporation | 6,11-Dihydro-11-(N-substituted-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-B)pyridines and compositions and methods of use |
| US5719148A (en) * | 1993-10-15 | 1998-02-17 | Schering Corporation | Tricyclic amide and urea compounds useful for inhibition of g-protein function and for treatment of proliferative diseases |
| IL111235A (en) * | 1993-10-15 | 2001-03-19 | Schering Plough Corp | Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them |
-
1998
- 1998-06-15 CA CA002293553A patent/CA2293553C/en not_active Expired - Fee Related
- 1998-06-15 CN CNB988082233A patent/CN1134433C/zh not_active Expired - Fee Related
- 1998-06-15 ES ES98928892T patent/ES2196566T3/es not_active Expired - Lifetime
- 1998-06-15 WO PCT/US1998/011510 patent/WO1998057965A1/en active IP Right Grant
- 1998-06-15 AU AU80586/98A patent/AU8058698A/en not_active Abandoned
- 1998-06-15 EP EP98928892A patent/EP0991643B1/de not_active Expired - Lifetime
- 1998-06-15 DE DE69812945T patent/DE69812945T2/de not_active Expired - Lifetime
- 1998-06-15 AT AT98928892T patent/ATE236149T1/de not_active IP Right Cessation
- 1998-06-15 JP JP50450499A patent/JP2002504151A/ja not_active Ceased
-
2000
- 2000-04-13 HK HK00102233A patent/HK1023339A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0991643A1 (de) | 2000-04-12 |
| ATE236149T1 (de) | 2003-04-15 |
| AU8058698A (en) | 1999-01-04 |
| CA2293553A1 (en) | 1998-12-23 |
| CN1134433C (zh) | 2004-01-14 |
| ES2196566T3 (es) | 2003-12-16 |
| CA2293553C (en) | 2008-01-22 |
| EP0991643B1 (de) | 2003-04-02 |
| JP2002504151A (ja) | 2002-02-05 |
| DE69812945T2 (de) | 2004-03-11 |
| HK1023339A1 (en) | 2000-09-08 |
| CN1267299A (zh) | 2000-09-20 |
| WO1998057965A1 (en) | 1998-12-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |