HK1016509A1 - Method and pharmaceutical composition for regulating lipid concentration - Google Patents

Method and pharmaceutical composition for regulating lipid concentration

Info

Publication number
HK1016509A1
HK1016509A1 HK99101732A HK99101732A HK1016509A1 HK 1016509 A1 HK1016509 A1 HK 1016509A1 HK 99101732 A HK99101732 A HK 99101732A HK 99101732 A HK99101732 A HK 99101732A HK 1016509 A1 HK1016509 A1 HK 1016509A1
Authority
HK
Hong Kong
Prior art keywords
pharmaceutical composition
lipid concentration
regulating lipid
regulating
concentration
Prior art date
Application number
HK99101732A
Other languages
English (en)
Inventor
Thomas M A Bocant
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21719566&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1016509(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of HK1016509A1 publication Critical patent/HK1016509A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/36—Antigestagens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
HK99101732A 1995-11-02 1999-04-21 Method and pharmaceutical composition for regulating lipid concentration HK1016509A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US615595P 1995-11-02 1995-11-02
PCT/US1996/015854 WO1997016184A1 (fr) 1995-11-02 1996-10-02 Procede et composition pharmaceutique visant a reguler la concentration lipidique

Publications (1)

Publication Number Publication Date
HK1016509A1 true HK1016509A1 (en) 1999-11-05

Family

ID=21719566

Family Applications (1)

Application Number Title Priority Date Filing Date
HK99101732A HK1016509A1 (en) 1995-11-02 1999-04-21 Method and pharmaceutical composition for regulating lipid concentration

Country Status (27)

Country Link
US (3) US6124309A (fr)
EP (1) EP0858336B1 (fr)
JP (1) JPH11515025A (fr)
KR (2) KR20040029459A (fr)
CN (2) CN1679953A (fr)
AR (1) AR004527A1 (fr)
AT (1) ATE348607T1 (fr)
AU (1) AU720853B2 (fr)
BG (1) BG64018B1 (fr)
BR (1) BR9611410A (fr)
CZ (1) CZ127198A3 (fr)
DE (1) DE69636783T2 (fr)
EA (1) EA000514B1 (fr)
ES (1) ES2279526T3 (fr)
GE (1) GEP20001898B (fr)
HK (1) HK1016509A1 (fr)
HU (1) HUP9901865A3 (fr)
IL (1) IL123902A (fr)
IS (1) IS4720A (fr)
NO (1) NO981961L (fr)
NZ (2) NZ319906A (fr)
PL (1) PL186714B1 (fr)
RO (1) RO120816B1 (fr)
SK (1) SK284142B6 (fr)
UA (1) UA46069C2 (fr)
WO (1) WO1997016184A1 (fr)
ZA (1) ZA969187B (fr)

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GT199800126A (es) * 1997-08-29 2000-01-29 Terapia de combinacion.
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WO1999047138A1 (fr) * 1998-03-17 1999-09-23 Warner-Lambert Company Associations statine-inhibiteur de metalloprotease matricielle
US6221897B1 (en) * 1998-06-10 2001-04-24 Aventis Pharma Deutschland Gmbh Benzothiepine 1,1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use
DK1117392T3 (da) * 1998-09-30 2004-06-14 Warner Lambert Co Fremgangsmåde til forhindring eller forsinkelse af kateterbaseret revaskularisation
CO5140104A1 (es) * 1999-02-16 2002-03-22 Novartis Ag Derivados de mevinolina y preparacion farmaceuticas que los contienen
US20010006656A1 (en) * 1999-02-17 2001-07-05 University Of Washington Methods and compositions for inhibiting inflammation associated with pulmonary disease
AU7717500A (en) * 1999-09-30 2001-04-30 Merck & Co., Inc. Anti-hypercholesterolemic drug combination
EP1092432A1 (fr) 1999-10-15 2001-04-18 Societe De Conseils De Recherches Et D'applications Scientifiques S.A. (S.C.R.A.S.) Composes anti-ischemiques
CA2382676A1 (fr) * 1999-11-05 2001-05-17 Warner-Lambert Company Prevention de la rupture de plaques par inhibiteurs de l'acat
WO2002020009A1 (fr) * 2000-09-01 2002-03-14 Sankyo Company, Limited Compositions medicales
EP1326822A2 (fr) 2000-10-11 2003-07-16 Esperion Therapeutics Inc. Composes de fonction cetone et compositions pour la regulation du taux de cholesterol, et utilisations associees
US6673780B2 (en) 2000-10-11 2004-01-06 Esperion Therapeutics, Inc. Sulfoxide and bis-sulfoxide compounds and compositions for cholesterol management and related uses
US20040122091A1 (en) * 2000-10-11 2004-06-24 Esperion Therapeutics, Inc. Sulfoxide and bis-sulfoxide compounds and compositions for cholesterol management and related uses
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CA2369967A1 (fr) * 2001-02-12 2002-08-12 Joseph Anthony Cornicelli Methodes de traitement de maladies et de troubles relies au facteur nucleaire-kappa b
PE20030324A1 (es) * 2001-07-31 2003-04-03 Warner Lambert Co Composiciones farmaceuticas de amlodipina y atorvastatina
US20050020694A1 (en) * 2001-10-11 2005-01-27 Dasseux Jean-Louis Henri Sulfide and disulfide compounds and compositions for cholesterol management and related uses
US20040204502A1 (en) * 2001-10-11 2004-10-14 Dasseux Jean-Louis Henri Sulfoxide and bis-sulfoxide compounds and compositions for cholesterol management and related uses
US20040192771A1 (en) * 2001-10-11 2004-09-30 Dasseux Jean-Louis Henri Ether compounds and compositions for cholesterol management and related uses
EP1485077A4 (fr) * 2002-03-12 2007-07-18 Merck & Co Inc Therapie par association de medicaments
AU2003230918A1 (en) * 2002-04-10 2003-10-27 Esperion Therapeutics, Inc. Mimics of acyl coenzyme-a, compositions thereof, and methods of cholesterol management and related uses
JP4187141B2 (ja) * 2002-04-12 2008-11-26 興和株式会社 新規なトロンボモジュリン発現促進剤
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US20090110760A1 (en) * 2003-11-07 2009-04-30 Toyo Shinyaku Co., Ltd. Lipometabolism improver containing pine bark extract
AU2003304703A1 (en) * 2003-12-24 2005-08-03 Esperion Therapeutics, Inc. Ketone compounds and compositions for cholesterol management and related uses
EP1737465A4 (fr) * 2004-04-19 2007-10-03 Univ Loma Linda Composition et procede de reduction de dommages ischemiques renaux
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TW200619204A (en) * 2004-12-10 2006-06-16 Kowa Co Method for reduction, stabilization and prevention of rupture of lipid rich plaque
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US20130254787A1 (en) 2006-05-02 2013-09-26 Invidi Technologies Corporation Method and apparatus to perform real-time audience estimation and commercial selection suitable for targeted advertising
US20070269503A1 (en) * 2006-05-16 2007-11-22 James Walter Burgess Combinations of HMG CoA reductase inhibitors and negatively charged phospholipids and uses thereof
US8314080B2 (en) 2010-04-06 2012-11-20 Kuwait University Method of treating type I diabetes
CN103288702B (zh) * 2010-12-03 2015-09-16 上海科州药物研发有限公司 一种阿托伐他汀氨基酸盐的制备方法
US8586527B2 (en) * 2011-10-20 2013-11-19 Jaipal Singh Cerivastatin to treat pulmonary disorders
CN104023727B (zh) 2011-10-28 2017-04-05 鲁美纳医药公司 用于治疗小儿胆汁淤积性肝病的胆汁酸再循环抑制剂
CN103304496A (zh) * 2012-03-08 2013-09-18 南京工业大学 一种合成申嗪霉素方法
US10047034B2 (en) 2012-05-16 2018-08-14 Prairie Berry Europe Gmbh Polyhydroxylated pentacyclic triterpene acids as HMG-COA reductase inhibitors
AU2016233485B2 (en) 2015-03-13 2021-05-20 Esperion Therapeutics, Inc. Fixed dose combinations and formulations comprising ETC1002 and Ezetimibe and methods of treating or reducing the risk of cardiovascular disease
MA41793A (fr) 2015-03-16 2018-01-23 Esperion Therapeutics Inc Associations de doses fixes comprenant du etc1002 et une ou plusieurs statines permettant de traiter ou de réduire un risque cardiovasculaire
WO2020257571A1 (fr) 2019-06-21 2020-12-24 Esperion Therapeutics, Inc. Procédés de préparation d'acide bempédoïque et compositions de celui-ci

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Also Published As

Publication number Publication date
IS4720A (is) 1998-04-17
ZA969187B (en) 1997-05-29
NO981961D0 (no) 1998-04-30
CN1679953A (zh) 2005-10-12
CZ127198A3 (cs) 1998-12-16
EA199800420A1 (ru) 1998-10-29
WO1997016184A1 (fr) 1997-05-09
BR9611410A (pt) 1999-01-05
AR004527A1 (es) 1998-12-16
NZ319906A (en) 2000-02-28
EP0858336A1 (fr) 1998-08-19
BG64018B1 (bg) 2003-10-31
UA46069C2 (uk) 2002-05-15
ES2279526T3 (es) 2007-08-16
PL326365A1 (en) 1998-09-14
US6124309A (en) 2000-09-26
SK284142B6 (sk) 2004-10-05
GEP20001898B (en) 2000-01-05
NO981961L (no) 1998-05-04
CN1201389A (zh) 1998-12-09
EP0858336B1 (fr) 2006-12-20
US6093719A (en) 2000-07-25
JPH11515025A (ja) 1999-12-21
CN1217656C (zh) 2005-09-07
HUP9901865A3 (en) 2000-06-28
EA000514B1 (ru) 1999-10-28
AU720853B2 (en) 2000-06-15
AU7253996A (en) 1997-05-22
US6143755A (en) 2000-11-07
KR100449604B1 (ko) 2004-11-16
ATE348607T1 (de) 2007-01-15
RO120816B1 (ro) 2006-08-30
IL123902A0 (en) 1998-10-30
DE69636783T2 (de) 2007-10-18
DE69636783D1 (de) 2007-02-01
HUP9901865A2 (hu) 1999-10-28
IL123902A (en) 2003-01-12
SK55798A3 (en) 1999-06-11
NZ512484A (en) 2003-02-28
BG102417A (en) 1999-01-29
KR19990067270A (ko) 1999-08-16
PL186714B1 (pl) 2004-02-27
KR20040029459A (ko) 2004-04-06

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