HK1013627A1 - High solubility multicomponent inclusion complexes consisting of an acidic drug a cyclodextrin and a base - Google Patents

High solubility multicomponent inclusion complexes consisting of an acidic drug a cyclodextrin and a base

Info

Publication number
HK1013627A1
HK1013627A1 HK98114995A HK98114995A HK1013627A1 HK 1013627 A1 HK1013627 A1 HK 1013627A1 HK 98114995 A HK98114995 A HK 98114995A HK 98114995 A HK98114995 A HK 98114995A HK 1013627 A1 HK1013627 A1 HK 1013627A1
Authority
HK
Hong Kong
Prior art keywords
cyclodextrin
base
inclusion complexes
high solubility
acidic drug
Prior art date
Application number
HK98114995A
Other languages
English (en)
Inventor
Paolo Chiesi
Paolo Ventura
Maurizio Del Canale
Maurizio Redenti
Daniela Acerbi
Massimo Pasini
Josef Szejtli
Maria Vikmon
Eva Fenyvesi
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Publication of HK1013627A1 publication Critical patent/HK1013627A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nanotechnology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
HK98114995A 1994-04-22 1998-12-23 High solubility multicomponent inclusion complexes consisting of an acidic drug a cyclodextrin and a base HK1013627A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI940790A IT1269578B (it) 1994-04-22 1994-04-22 Complessi di inclusione multicomponente ad elevata solubilita' costituiti da un farmaco di tipo acido, una ciclodestrina e una base.
PCT/EP1995/001407 WO1995028965A1 (fr) 1994-04-22 1995-04-13 Complexes a insertion, a plusieurs constituants et hautement solubles, contenant un medicament acide, une cyclodextrine ainsi qu'une base

Publications (1)

Publication Number Publication Date
HK1013627A1 true HK1013627A1 (en) 1999-09-03

Family

ID=11368715

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98114995A HK1013627A1 (en) 1994-04-22 1998-12-23 High solubility multicomponent inclusion complexes consisting of an acidic drug a cyclodextrin and a base

Country Status (13)

Country Link
US (1) US5773029A (fr)
EP (1) EP0756493B1 (fr)
AT (1) ATE194777T1 (fr)
AU (1) AU2307695A (fr)
CA (1) CA2188388A1 (fr)
DE (1) DE69518070T2 (fr)
ES (1) ES2148512T3 (fr)
HK (1) HK1013627A1 (fr)
IL (1) IL113450A (fr)
IT (1) IT1269578B (fr)
PT (1) PT756493E (fr)
WO (1) WO1995028965A1 (fr)
ZA (1) ZA953206B (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997018245A1 (fr) * 1995-11-14 1997-05-22 Farmarc Nederland B.V. Complexe de naproxene et de beta-cyclodextrine
UA57734C2 (uk) 1996-05-07 2003-07-15 Пфайзер Інк. Комплекси включення арилгетероциклічних солей
EP0811386B1 (fr) * 1996-05-07 2004-09-29 Pfizer Inc. Méthode de sélection d'un sel pour fabrication d'un complexe d'inclusion
US6383471B1 (en) 1999-04-06 2002-05-07 Lipocine, Inc. Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents
US6939863B2 (en) 2002-01-04 2005-09-06 Wei-Jan Chen Prevention of atherosclerosis and restenosis
CA2480826C (fr) * 2002-04-09 2012-02-07 Flamel Technologies Formulation pharmaceutique orale sous forme de suspension aqueuse de microcapsules permettant la liberation modifiee de principe(s) actif(s)
ES2286177T3 (es) * 2002-06-17 2007-12-01 Chiesi Farmaceutici S.P.A. Procedimiento para la preparacion de piroxicam: compuestos de inclusion de betaciclodextrina.
BR0313602A (pt) * 2002-08-20 2005-06-21 Bristol Myers Squibb Co Método e formulação de complexo de aripiprazol
US7993654B2 (en) 2002-12-23 2011-08-09 Beiersdorf Ag Self-adhesive polymer matrix containing sea algae extract
DE10260873A1 (de) 2002-12-23 2004-07-15 Beiersdorf Ag Selbstklebende Polymermatrix mit einem Gehalt an Meeresalgenextrakt und Glycerin
DE10260872B4 (de) * 2002-12-23 2013-09-26 Beiersdorf Ag Verwendung von gelbildendem Polymer, Wasser, Alkohol und Meeresalgenextrakt zur Einstellung von Elastizität und Haftvermögen selbstklebender kosmetischer Polymermatrices
US20070020578A1 (en) * 2005-07-19 2007-01-25 Scott Robert R Dental curing light having a short wavelength LED and a fluorescing lens for converting wavelength light to curing wavelengths and related method
WO2006034147A2 (fr) * 2004-09-16 2006-03-30 Abraxis Bioscience, Inc. Compositions et procedes de preparation et d'administration de medicaments faiblement solubes dans l'eau
US8772346B2 (en) * 2005-11-09 2014-07-08 Torrent Pharmaceuticals Limited Pharmaceutical composition
FR2914187B1 (fr) * 2007-03-28 2011-01-21 Pf Medicament Complexes d'ibuprofene, de cyclodextrines et d'agents ternaires, et leurs utilisations en pharmaceutique.
US11020363B2 (en) 2009-05-29 2021-06-01 Cydex Pharmaceuticals, Inc. Injectable nitrogen mustard compositions comprising a cyclodextrin derivative and methods of making and using the same
US20100311838A1 (en) 2009-05-29 2010-12-09 Pipkin James D Injectable Melphalan Compositions Comprising a Cyclodextrin Derivative and Methods of Making and Using the Same
CN108210501B (zh) * 2016-12-14 2019-03-08 中国人民解放军军事医学科学院毒物药物研究所 一种磺酰脲类药物的注射用药物组合物及其制备方法
TW202302117A (zh) * 2021-03-04 2023-01-16 美商渤健切薩皮克有限公司 低吸附格列本脲調配物及方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1196033B (it) * 1984-02-22 1988-11-10 Chiesi Farma Spa Composto ad attivita' antiinfiammatoria ottenuto per complessazione con beta-ciclodestrina e relative formulazioni farmaceutiche
BE1001704A3 (fr) * 1987-12-22 1990-02-13 Glaxo Group Ltd Compositions aqueuses contenant un derive de l'acide piperidinylcyclopentylheptenoique.
IT1263831B (it) * 1993-01-29 1996-09-04 Paolo Chiesi Complessi di inclusione multicomponente ad elevata solubilita' costituiti da un farmaco di tipo basico, un acido ed una ciclodestrina

Also Published As

Publication number Publication date
DE69518070T2 (de) 2001-01-11
IT1269578B (it) 1997-04-08
ATE194777T1 (de) 2000-08-15
US5773029A (en) 1998-06-30
EP0756493B1 (fr) 2000-07-19
IL113450A0 (en) 1995-07-31
ITMI940790A1 (it) 1995-10-22
PT756493E (pt) 2000-10-31
EP0756493A1 (fr) 1997-02-05
IL113450A (en) 1999-05-09
ITMI940790A0 (it) 1994-04-22
ES2148512T3 (es) 2000-10-16
CA2188388A1 (fr) 1995-11-02
WO1995028965A1 (fr) 1995-11-02
AU2307695A (en) 1995-11-16
DE69518070D1 (de) 2000-08-24
ZA953206B (en) 1996-01-03

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20050413