HK1012356A1 - 3,9-diazabicyclo (3.3.1) nonan-7-yl derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them - Google Patents

3,9-diazabicyclo (3.3.1) nonan-7-yl derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them

Info

Publication number
HK1012356A1
HK1012356A1 HK98113476A HK98113476A HK1012356A1 HK 1012356 A1 HK1012356 A1 HK 1012356A1 HK 98113476 A HK98113476 A HK 98113476A HK 98113476 A HK98113476 A HK 98113476A HK 1012356 A1 HK1012356 A1 HK 1012356A1
Authority
HK
Hong Kong
Prior art keywords
alkyl
phenyl
nonan
diazabicyclo
intermediates
Prior art date
Application number
HK98113476A
Other languages
English (en)
Inventor
Francis David King
Julian Anthony Gregory
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of HK1012356A1 publication Critical patent/HK1012356A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK98113476A 1990-09-26 1998-12-15 3,9-diazabicyclo (3.3.1) nonan-7-yl derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them HK1012356A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909020927A GB9020927D0 (en) 1990-09-26 1990-09-26 Pharmaceuticals
PCT/GB1991/001629 WO1992005174A1 (en) 1990-09-26 1991-09-23 3,9-diazabicyclo (3.3.1) nonan-7-yl derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
HK1012356A1 true HK1012356A1 (en) 1999-07-30

Family

ID=10682769

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98113476A HK1012356A1 (en) 1990-09-26 1998-12-15 3,9-diazabicyclo (3.3.1) nonan-7-yl derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them

Country Status (19)

Country Link
EP (1) EP0550550B1 (es)
JP (1) JP2831464B2 (es)
KR (1) KR100200438B1 (es)
AT (1) ATE245157T1 (es)
AU (1) AU652187B2 (es)
CA (1) CA2092431C (es)
CY (1) CY2387B1 (es)
DE (1) DE69133295T2 (es)
DK (1) DK0550550T3 (es)
ES (1) ES2203609T3 (es)
GB (1) GB9020927D0 (es)
HK (1) HK1012356A1 (es)
IE (1) IE913352A1 (es)
MX (1) MX9101236A (es)
NZ (1) NZ239915A (es)
PT (1) PT99028B (es)
TW (1) TW240227B (es)
WO (1) WO1992005174A1 (es)
ZA (1) ZA917606B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9121170D0 (en) * 1991-10-05 1991-11-20 Smithkline Beecham Plc Pharmaceuticals
US5344831A (en) * 1992-01-31 1994-09-06 Nisshin Flour Milling Co., Ltd. Diazabicyclo derivatives
GB9214184D0 (en) * 1992-07-03 1992-08-12 Smithkline Beecham Plc Pharmaceuticals
US5514690A (en) * 1992-11-17 1996-05-07 E. R. Squibb & Sons, Inc. Aminocarbonyl (thiocarbonyl) and cyanoguanidine derivatives of quinoline and indoline
US5629429A (en) * 1995-06-07 1997-05-13 Bristol-Myers Squibb Company Process for preparing 4-arylamino-benzopyran and related compounds
US5612323A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phosphinic ester substituted benzopyran derivatives
US5869478A (en) * 1995-06-07 1999-02-09 Bristol-Myers Squibb Company Sulfonamido substituted benzopyran derivatives
US5612370A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phenylglycine and phenylalaninen amido benzopyran derivatives
GB9721139D0 (en) 1997-10-07 1997-12-03 Glaxo Group Ltd Medicaments
EP1501830B1 (en) 2002-04-29 2011-10-05 Actelion Pharmaceuticals Ltd. 7-aryl-3,9-diazabicyclo[3.3.1]non-6-ene derivatives and their use as renin inhibitors in the treatment of hypertension, cardiovascular or renal diseases
WO2005040165A1 (en) * 2003-10-13 2005-05-06 Actelion Pharmaceuticals Ltd Diazabicyclononene derivatives and their use as renin inhibitors
WO2005123718A2 (en) 2004-06-15 2005-12-29 Pfizer Japan Inc. Benzimidazolone carboxylic acid derivatives
US7737163B2 (en) 2004-06-15 2010-06-15 Pfizer Inc. Benzimidazolone carboxylic acid derivatives
AP2007004067A0 (en) 2005-02-22 2007-08-31 Pfizer Oxyindole derivatives as 5HT4 receptor agonists
US8129538B1 (en) 2007-03-28 2012-03-06 Takeda Pharmaceutical Company Limited Renin inhibitors
GB201511382D0 (en) 2015-06-29 2015-08-12 Imp Innovations Ltd Novel compounds and their use in therapy

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0498466B1 (en) * 1985-04-27 2002-07-24 F. Hoffmann-La Roche Ag Indazole-3-carboxamide and -3-carboxylic acid derivatives
HU202108B (en) * 1986-07-30 1991-02-28 Sandoz Ag Process for producing pharmaceutical compositions containing serotonine antqgonistic derivatives of indol-carboxylic acid or imidazolyl-methyl-carbazol
US4920227A (en) * 1988-11-29 1990-04-24 Rorer Pharmaceutical Corp. Benzobicyclic carboxamide 5-HT3 antagonists
US4920219A (en) * 1988-11-29 1990-04-24 Rorer Pharmaceutical Corp. Substituted saturated and unsaturated indole quinoline and benzazepine carboxamides and their use as pharmacological agents

Also Published As

Publication number Publication date
AU8624491A (en) 1992-04-15
PT99028A (pt) 1993-10-29
DK0550550T3 (da) 2003-09-08
DE69133295T2 (de) 2004-03-18
GB9020927D0 (en) 1990-11-07
EP0550550A1 (en) 1993-07-14
CA2092431A1 (en) 1992-03-27
MX9101236A (es) 1992-05-04
TW240227B (es) 1995-02-11
EP0550550B1 (en) 2003-07-16
ES2203609T3 (es) 2004-04-16
ATE245157T1 (de) 2003-08-15
WO1992005174A1 (en) 1992-04-02
AU652187B2 (en) 1994-08-18
KR930702345A (ko) 1993-09-08
CY2387B1 (en) 2004-09-10
PT99028B (pt) 1999-02-26
IE913352A1 (en) 1992-04-08
CA2092431C (en) 2002-12-10
ZA917606B (en) 1992-09-30
NZ239915A (en) 1993-11-25
DE69133295D1 (de) 2003-08-21
KR100200438B1 (ko) 1999-06-15
JP2831464B2 (ja) 1998-12-02
JPH06501256A (ja) 1994-02-10

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Legal Events

Date Code Title Description
PF Patent in force
PE Patent expired

Effective date: 20110922