HK1010054A1 - 4"-deoxyerythromycin derivatives - Google Patents

4"-deoxyerythromycin derivatives

Info

Publication number
HK1010054A1
HK1010054A1 HK98110890A HK98110890A HK1010054A1 HK 1010054 A1 HK1010054 A1 HK 1010054A1 HK 98110890 A HK98110890 A HK 98110890A HK 98110890 A HK98110890 A HK 98110890A HK 1010054 A1 HK1010054 A1 HK 1010054A1
Authority
HK
Hong Kong
Prior art keywords
derivatives
deoxyerythromycin
deoxyerythromycin derivatives
erythromycin
enhancers
Prior art date
Application number
HK98110890A
Other languages
English (en)
Inventor
Paul A Lartey
Hugh N Nellans
Larry L Klein
Ramin Faghih
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of HK1010054A1 publication Critical patent/HK1010054A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Otolaryngology (AREA)
  • Hospice & Palliative Care (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
HK98110890A 1992-01-21 1998-09-23 4"-deoxyerythromycin derivatives HK1010054A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US82349092A 1992-01-21 1992-01-21
US94415092A 1992-09-11 1992-09-11
PCT/US1993/000468 WO1993013780A1 (en) 1992-01-21 1993-01-19 4''-deoxyerythromycin derivatives

Publications (1)

Publication Number Publication Date
HK1010054A1 true HK1010054A1 (en) 1999-06-11

Family

ID=27124738

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98110890A HK1010054A1 (en) 1992-01-21 1998-09-23 4"-deoxyerythromycin derivatives

Country Status (16)

Country Link
US (3) US5578579A (xx)
EP (1) EP0623021B1 (xx)
JP (1) JP2662094B2 (xx)
KR (1) KR0179379B1 (xx)
AT (1) ATE164848T1 (xx)
AU (1) AU656462B2 (xx)
CA (1) CA2125478A1 (xx)
DE (1) DE69317877T2 (xx)
DK (1) DK0623021T3 (xx)
ES (1) ES2115760T3 (xx)
HK (1) HK1010054A1 (xx)
HU (1) HU211337A9 (xx)
IL (1) IL104437A (xx)
MX (1) MX9300278A (xx)
PH (1) PH31561A (xx)
WO (1) WO1993013780A1 (xx)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY113693A (en) * 1992-05-26 2002-05-31 Chugai Pharmaceutical Co Ltd Erythromycin derivatives having an enterokinesis stimulating action
US5922849A (en) * 1996-11-22 1999-07-13 Abbott Laboratories Process for preparation of N-demethyl-4"-deoxy-erthromycins A and B
US5760198A (en) * 1997-01-17 1998-06-02 Abbott Laboratories Process for preparation of 4"-deoxyerythromycins A and B
US7910548B2 (en) * 1997-06-06 2011-03-22 Amylin Pharmaceuticals, Inc. Methods for treating obesity
US5780605A (en) * 1997-09-08 1998-07-14 Abbott Laboratories 6,9-bridged erythromycin derivatives
US5883236A (en) * 1997-11-19 1999-03-16 Abbott Laboratories Process for N-desmethylating erythromycins and derivatives thereof
US5932710A (en) * 1997-12-01 1999-08-03 Abbott Laboratories Process for preparing 6-O-alkyl-9-oxime erythromycin B
US6040440A (en) * 1998-03-06 2000-03-21 Abbott Laboratories Hypophosphite deoxygenation reactions in the synthesis of erythromycin derivatives
US6084079A (en) * 1998-05-15 2000-07-04 Keyes; Robert F. Process for preparing N-demethyl-N-alkyl erythromycin derivatives
AU2001238476A1 (en) 2000-02-18 2001-08-27 Kosan Biosciences, Inc. Motocide compounds
CA2437576A1 (en) 2001-02-15 2002-08-22 Kosan Biosciences, Inc. Method for evaluating therapeutic efficacy
JP4796300B2 (ja) * 2002-08-29 2011-10-19 ファイザー インコーポレイテッド モチライド化合物
US7635714B2 (en) 2002-10-25 2009-12-22 Chugai Seiyaku Kabushiki Kaisha Methods of treating dyschezia
US7407941B2 (en) * 2003-08-26 2008-08-05 Pfizer, Inc. N-desmethyl-N-substituted-11-deoxyerythromycin compounds
US20050113319A1 (en) * 2003-08-26 2005-05-26 Christopher Carreras 11-Deoxy-6,9-ether erythromycin compounds
US7211568B2 (en) * 2003-12-18 2007-05-01 Kosan Biosciences Incorporated 9-Desoxoerythromycin compounds as prokinetic agents
US7582611B2 (en) * 2005-05-24 2009-09-01 Pfizer Inc. Motilide compounds
CA2632779A1 (en) * 2005-12-08 2007-06-14 Pfizer Inc. Method for demethylating the 3'-dimethylamino group of erythromycin compounds
CN101528765B (zh) 2006-09-11 2015-04-22 欧塞拉治疗有限公司 用于治疗胃肠动力障碍病症的促胃动素受体的大环拮抗剂
AU2007330456B2 (en) 2006-12-05 2011-03-03 Pfizer Inc. Motilide polymorphs
US20080287371A1 (en) * 2007-05-17 2008-11-20 Tranzyme Pharma Inc. Macrocyclic antagonists of the motilin receptor for modulation of the migrating motor complex

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5849396A (ja) * 1981-09-07 1983-03-23 Toyo Jozo Co Ltd ４″−デオキシ−１４員環マクロライド抗生物質
JPS6187625A (ja) * 1984-10-05 1986-05-06 Satoshi Omura 消化管収縮運動促進剤
US5008249A (en) * 1985-08-31 1991-04-16 Kitasato Kenkyusho Therapeutic method of stimulating digestive tract contractile motion in mammals
US5175150A (en) * 1985-08-31 1992-12-29 Kitasato, Kenkyusho Erythromycin derivative
EP0215355B1 (en) * 1985-08-31 1994-04-06 Kitasato Kenkyusho Erythromycin derivative and process for preparing the same
US4681872A (en) 1985-11-12 1987-07-21 Abbott Laboratories Erythromycin A 11,12-carbonate and method of use
US4640910A (en) * 1985-11-12 1987-02-03 Abbott Laboratories Erythromycin A silylated compounds and method of use
JPS63107994A (ja) * 1986-05-02 1988-05-12 Taisho Pharmaceut Co Ltd エリスロマイシン誘導体
MY103197A (en) 1987-02-20 1993-05-29 Kitasato Inst A growth promoting composition and production thereof
US4920102A (en) * 1988-04-18 1990-04-24 Eli Lilly And Company Method for treating gastrointestinal disorders

Also Published As

Publication number Publication date
AU656462B2 (en) 1995-02-02
HU211337A9 (en) 1995-11-28
US5578579A (en) 1996-11-26
EP0623021B1 (en) 1998-04-08
AU3586193A (en) 1993-08-03
CA2125478A1 (en) 1993-07-22
WO1993013780A1 (en) 1993-07-22
DE69317877D1 (en) 1998-05-14
ES2115760T3 (es) 1998-07-01
IL104437A0 (en) 1993-05-13
JPH06511257A (ja) 1994-12-15
US5654411A (en) 1997-08-05
DE69317877T2 (de) 1998-10-29
EP0623021A1 (en) 1994-11-09
IL104437A (en) 1997-03-18
EP0623021A4 (en) 1994-12-14
KR0179379B1 (ko) 1999-04-01
JP2662094B2 (ja) 1997-10-08
US5834438A (en) 1998-11-10
ATE164848T1 (de) 1998-04-15
PH31561A (en) 1998-11-03
MX9300278A (es) 1993-12-31
DK0623021T3 (da) 1999-02-08

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)