HK1009330A1 - Desferrioxamine-b salts and their use as orally effective iron chelators - Google Patents

Desferrioxamine-b salts and their use as orally effective iron chelators Download PDF

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Publication number
HK1009330A1
HK1009330A1 HK98109975A HK98109975A HK1009330A1 HK 1009330 A1 HK1009330 A1 HK 1009330A1 HK 98109975 A HK98109975 A HK 98109975A HK 98109975 A HK98109975 A HK 98109975A HK 1009330 A1 HK1009330 A1 HK 1009330A1
Authority
HK
Hong Kong
Prior art keywords
salt
sulphonic acid
desferrioxamine
acid
formula
Prior art date
Application number
HK98109975A
Other languages
German (de)
English (en)
French (fr)
Chinese (zh)
Other versions
HK1009330B (en
Inventor
Lowther Nicholas
Francis Hassan Ian
Timothy William Matthews Ian
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of HK1009330A1 publication Critical patent/HK1009330A1/en
Publication of HK1009330B publication Critical patent/HK1009330B/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
HK98109975.3A 1992-06-03 1998-08-18 Desferrioxamine-b salts and their use as orally effective iron chelators HK1009330B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929211779A GB9211779D0 (en) 1992-06-03 1992-06-03 Amine salts
GB9211779 1992-06-03

Publications (2)

Publication Number Publication Date
HK1009330A1 true HK1009330A1 (en) 1999-05-28
HK1009330B HK1009330B (en) 1999-05-28

Family

ID=

Also Published As

Publication number Publication date
DE69318711D1 (de) 1998-06-25
NO944617L (no) 1995-01-05
KR950701907A (ko) 1995-05-17
NO302749B1 (no) 1998-04-20
DK0643690T3 (da) 1999-01-25
AU4270093A (en) 1993-12-30
EP0643690A1 (en) 1995-03-22
EP0643690B1 (en) 1998-05-20
US5739167A (en) 1998-04-14
AU672607B2 (en) 1996-10-10
US5663201A (en) 1997-09-02
TW230203B (cs) 1994-09-11
ES2117132T3 (es) 1998-08-01
GB9211779D0 (en) 1992-07-15
WO1993024451A1 (en) 1993-12-09
DE69318711T2 (de) 1998-11-19
NZ252738A (en) 1996-08-27
FI945654A7 (fi) 1994-11-30
NO944617D0 (no) 1994-12-01
ATE166342T1 (de) 1998-06-15
CA2135394A1 (en) 1993-12-09
JPH07507288A (ja) 1995-08-10
FI945654A0 (fi) 1994-11-30

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)