HK1006312A1 - Lipid a analogues having immuniactivating and anti-tumour activity - Google Patents
Lipid a analogues having immuniactivating and anti-tumour activityInfo
- Publication number
- HK1006312A1 HK1006312A1 HK98105528A HK98105528A HK1006312A1 HK 1006312 A1 HK1006312 A1 HK 1006312A1 HK 98105528 A HK98105528 A HK 98105528A HK 98105528 A HK98105528 A HK 98105528A HK 1006312 A1 HK1006312 A1 HK 1006312A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- hydroxy
- substituted
- fluorine
- lipid
- aliphatic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
- C07H11/04—Phosphates; Phosphites; Polyphosphates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
- C07H13/06—Fatty acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
- C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
- C07H5/06—Aminosugars
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Crystallography & Structural Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Fats And Perfumes (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Liquid Crystal Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1321153A JP2839921B2 (ja) | 1988-12-27 | 1989-12-11 | リピドaモノサッカライド類縁体 |
JP3733990 | 1990-02-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1006312A1 true HK1006312A1 (en) | 1999-02-19 |
Family
ID=26376476
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK98105528A HK1006312A1 (en) | 1989-12-11 | 1998-06-17 | Lipid a analogues having immuniactivating and anti-tumour activity |
Country Status (17)
Country | Link |
---|---|
US (1) | US5792840A (xx) |
EP (1) | EP0437016B1 (xx) |
KR (1) | KR0183315B1 (xx) |
CN (1) | CN1029405C (xx) |
AT (1) | ATE137504T1 (xx) |
CA (1) | CA2019972C (xx) |
CZ (1) | CZ285583B6 (xx) |
DD (1) | DD295854A5 (xx) |
DE (1) | DE69026808T2 (xx) |
DK (1) | DK0437016T3 (xx) |
ES (1) | ES2088970T3 (xx) |
GR (1) | GR3020131T3 (xx) |
HK (1) | HK1006312A1 (xx) |
HU (1) | HU217114B (xx) |
IE (1) | IE74209B1 (xx) |
PT (1) | PT94481B (xx) |
RU (2) | RU1836378C (xx) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2135536A1 (en) * | 1993-11-12 | 1995-05-13 | Hironori Kurita | Glucosamine derivative, process for preparing the same and synthetic intermediate thereof |
US5750664A (en) | 1995-06-05 | 1998-05-12 | Eisai Co., Ltd. | Substituted liposaccharides useful in the treatment and prevention of endotoxemia |
US6368604B1 (en) * | 1997-09-26 | 2002-04-09 | University Of Maryland Biotechnology Institute | Non-pyrogenic derivatives of lipid A |
WO2001058920A2 (fr) * | 2000-02-10 | 2001-08-16 | Mitsui Chemicals, Inc. | Procede de production selective d'un anomere derive d'un sucre 1-phosphoryle |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60501259A (ja) * | 1983-05-06 | 1985-08-08 | ウイスコンシン・アルムニ・リサ−チ・フアンデ−シヨン | 免疫刺激活性をもつ単糖類化合物 |
HU199494B (en) * | 1985-06-28 | 1990-02-28 | Sandoz Ag | Process for producing new saccharides and pharmaceutical compositions comprising same |
GB2211503B (en) * | 1985-06-28 | 1990-01-31 | Sandoz Ltd | New saccharides, their preparation and pharmaceutical compositions containing them |
DE3731953A1 (de) * | 1987-09-23 | 1989-04-06 | Sandoz Ag | Neue saccharide, verfahren zu ihrer herstellung und ihre verwendung |
US4746742A (en) * | 1985-11-28 | 1988-05-24 | Toho Yakuhin Kogyo Kabushiki Kaisha | Analogs of nonreducing monosaccharide moiety of lipid A |
US4912094B1 (en) * | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
DE3834377A1 (de) * | 1988-10-10 | 1990-04-12 | Medav Digitale Signalverarbeit | Verfahren zur automatischen erkennung und klassifizierung von digital quadratur-amplituden-modulierten signalen mit unbekannten parametern |
DE3834877A1 (de) * | 1988-10-13 | 1990-05-03 | Sandoz Ag | Neue saccharide, verfahren zu ihrer herstellung und ihre verwendung |
-
1990
- 1990-06-25 PT PT94481A patent/PT94481B/pt not_active IP Right Cessation
- 1990-06-25 RU SU904830600A patent/RU1836378C/ru active
- 1990-06-25 DD DD90342041A patent/DD295854A5/de not_active IP Right Cessation
- 1990-06-26 IE IE231290A patent/IE74209B1/en unknown
- 1990-06-26 CZ CS903185A patent/CZ285583B6/cs not_active IP Right Cessation
- 1990-06-26 CN CN90106805A patent/CN1029405C/zh not_active Expired - Fee Related
- 1990-06-26 HU HU903991A patent/HU217114B/hu not_active IP Right Cessation
- 1990-06-27 DE DE69026808T patent/DE69026808T2/de not_active Expired - Fee Related
- 1990-06-27 EP EP90307045A patent/EP0437016B1/en not_active Expired - Lifetime
- 1990-06-27 CA CA002019972A patent/CA2019972C/en not_active Expired - Fee Related
- 1990-06-27 DK DK90307045.6T patent/DK0437016T3/da active
- 1990-06-27 ES ES90307045T patent/ES2088970T3/es not_active Expired - Lifetime
- 1990-06-27 AT AT90307045T patent/ATE137504T1/de not_active IP Right Cessation
-
1992
- 1992-09-09 RU SU925052656A patent/RU2076107C1/ru active
-
1994
- 1994-07-26 US US08/280,298 patent/US5792840A/en not_active Expired - Fee Related
-
1996
- 1996-05-31 GR GR960401511T patent/GR3020131T3/el unknown
-
1998
- 1998-06-17 HK HK98105528A patent/HK1006312A1/xx not_active IP Right Cessation
- 1998-09-11 KR KR1019980037538A patent/KR0183315B1/ko not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0437016A2 (en) | 1991-07-17 |
RU2076107C1 (ru) | 1997-03-27 |
KR0183315B1 (ko) | 1999-04-01 |
DD295854A5 (de) | 1991-11-14 |
EP0437016B1 (en) | 1996-05-01 |
HU903991D0 (en) | 1990-11-28 |
CA2019972C (en) | 2000-08-08 |
CZ285583B6 (cs) | 1999-09-15 |
CA2019972A1 (en) | 1991-06-11 |
IE74209B1 (en) | 1997-07-16 |
HUT55793A (en) | 1991-06-28 |
HU217114B (hu) | 1999-11-29 |
ES2088970T3 (es) | 1996-10-01 |
US5792840A (en) | 1998-08-11 |
EP0437016A3 (en) | 1991-07-24 |
DE69026808T2 (de) | 1997-01-09 |
GR3020131T3 (en) | 1996-08-31 |
RU1836378C (ru) | 1993-08-23 |
CZ318590A3 (cs) | 1999-06-16 |
ATE137504T1 (de) | 1996-05-15 |
IE902312A1 (en) | 1991-06-19 |
PT94481A (pt) | 1991-08-14 |
DE69026808D1 (de) | 1996-06-05 |
CN1052481A (zh) | 1991-06-26 |
DK0437016T3 (da) | 1996-08-12 |
PT94481B (pt) | 1997-02-28 |
CN1029405C (zh) | 1995-08-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |