HK1005807A1 - Mpl ligand analogs - Google Patents

Mpl ligand analogs

Info

Publication number
HK1005807A1
HK1005807A1 HK98104636A HK98104636A HK1005807A1 HK 1005807 A1 HK1005807 A1 HK 1005807A1 HK 98104636 A HK98104636 A HK 98104636A HK 98104636 A HK98104636 A HK 98104636A HK 1005807 A1 HK1005807 A1 HK 1005807A1
Authority
HK
Hong Kong
Prior art keywords
mpl ligand
analogs
ligand analogs
mpl
amino acids
Prior art date
Application number
HK98104636A
Other languages
English (en)
Inventor
Steven G Elliott
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/388,779 external-priority patent/US5696250A/en
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of HK1005807A1 publication Critical patent/HK1005807A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Luminescent Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
HK98104636A 1995-02-15 1998-05-28 Mpl ligand analogs HK1005807A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/388,779 US5696250A (en) 1995-02-15 1995-02-15 DNA encoding megakaryocyte growth and development factor analogs
US08/591,070 US5756083A (en) 1995-02-15 1996-02-09 Mpl ligand analogs
PCT/US1996/002492 WO1996025498A2 (en) 1995-02-15 1996-02-13 Mpl ligand analogs

Publications (1)

Publication Number Publication Date
HK1005807A1 true HK1005807A1 (en) 1999-01-29

Family

ID=27012437

Family Applications (2)

Application Number Title Priority Date Filing Date
HK98104636A HK1005807A1 (en) 1995-02-15 1998-05-28 Mpl ligand analogs
HK98109942A HK1009151A1 (en) 1995-02-15 1998-08-14 Mpl ligand analogs mpl.

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK98109942A HK1009151A1 (en) 1995-02-15 1998-08-14 Mpl ligand analogs mpl.

Country Status (11)

Country Link
EP (1) EP0811064B1 (es)
JP (1) JP3836877B2 (es)
CN (1) CN1161468C (es)
AT (1) ATE323724T1 (es)
AU (1) AU691410B2 (es)
CA (1) CA2209298C (es)
DE (1) DE69636052T2 (es)
HK (2) HK1005807A1 (es)
MX (1) MX9705943A (es)
NZ (1) NZ303588A (es)
WO (1) WO1996025498A2 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8192955B1 (en) 1994-01-03 2012-06-05 Genentech, Inc. Nucleic acids encoding MPL ligand (thrombopoietin), variants, and fragments thereof
US8357513B1 (en) 1994-01-03 2013-01-22 Genentech, Inc. Nucleic acids encoding mpl ligand (thrombopoietin) and fragments thereof
US8241900B1 (en) 1994-01-03 2012-08-14 Genentech, Inc. mpl ligand
US5989538A (en) * 1995-02-15 1999-11-23 Amgen Inc. Mpl ligand analogs
KR20050084473A (ko) * 1996-09-13 2005-08-26 트랜스케리오틱 쎄러피스, 인코포레이티드 α-갈락토시다아제 Ａ 결핍을 치료하는 방법
KR100408229B1 (ko) * 1996-10-04 2003-12-01 암겐 인코포레이티드 Ｍｐｌ 리간드를 함유하는 제약학적 조성물
KR20000006549A (ko) * 1998-06-30 2000-01-25 윤재승 생체내혈소판증식효능이향상된신규한트롬보포이에틴유도체
US20030228666A1 (en) 1998-06-30 2003-12-11 Daewoong Pharmaceutical Co., Ltd. Novel human thrombopoietin mutein
EP1216037A2 (en) 1999-09-21 2002-06-26 Emory University Methods and compositions for treating platelet-related disorders using mpl pathway inhibitory agents
JP2007528195A (ja) * 2003-10-09 2007-10-11 デウン カンパニー，リミテッド 高シアル酸含量のヒトトロンボポエチンを精製する方法
US20110294733A1 (en) 2009-01-20 2011-12-01 Hanall Biopharma Co., Ltd. Modified human thrombopoietin polypeptide fragment and manufacturing method thereof
EP2820149A1 (en) * 2012-02-27 2015-01-07 Biogen Idec MA Inc. High-throughput method for sialic acid quantitation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2285446B (en) * 1994-01-03 1999-07-28 Genentech Inc Thrombopoietin
DE19500030A1 (de) * 1994-01-03 1995-07-06 Genentech Inc Thrombopoietin
EP0668352A1 (en) * 1994-02-14 1995-08-23 Kirin Brewery Company, Ltd. Protein having TPO activity
US5766581A (en) * 1994-03-31 1998-06-16 Amgen Inc. Method for treating mammals with monopegylated proteins that stimulates megakaryocyte growth and differentiation
WO1996017062A1 (en) * 1994-11-30 1996-06-06 Zymogenetics, Inc. Low molecular weight thrombopoietin
AU4658596A (en) * 1995-02-03 1996-08-21 G.D. Searle & Co. Novel c-mpl ligands

Also Published As

Publication number Publication date
ATE323724T1 (de) 2006-05-15
CA2209298C (en) 2001-12-18
WO1996025498A3 (en) 1997-03-20
CN1182453A (zh) 1998-05-20
DE69636052T2 (de) 2007-04-12
AU691410B2 (en) 1998-05-14
DE69636052D1 (de) 2006-05-24
CA2209298A1 (en) 1996-08-22
CN1161468C (zh) 2004-08-11
NZ303588A (en) 1999-02-25
JP3836877B2 (ja) 2006-10-25
EP0811064B1 (en) 2006-04-19
HK1009151A1 (en) 1999-09-10
MX9705943A (es) 1997-10-31
WO1996025498A2 (en) 1996-08-22
EP0811064A2 (en) 1997-12-10
JPH11500904A (ja) 1999-01-26
AU4994696A (en) 1996-09-04

Similar Documents

Publication Publication Date Title
EP0662827A4 (en) THERAPEUTIC AND DIAGNOSTIC METHODS AND COMPOSITIONS BASED ON NOTCH PROTEINS AND NUCLEIC ACIDS.
EP1440980A3 (en) Peptide analogs of human myelin basic protein
AU3498189A (en) Fibronectin binding protein
UA49793C2 (uk) Аналог еритропоетину людини (варіанти), молекула днк, що кодує аналог еритропоетину людини (варіанти), еукаріотична клітина-хазяїн, трансфікована молекулою днк (варіанти), фармацевтична композиція (варіанти)
EP1308515A3 (en) Porcine factor VIII
AU1672388A (en) Expression of human proapolipoprotein a-i
IL113979A0 (en) Process for preparing cardiodilatin fragments highly purified cardiodilatin fragments and intermediate products for the preparation of same
AU9084601A (en) G-csf analog compositions and methods
AU9315398A (en) Chemokine peptides, variants, derivatives and analogs. their use in methods to inhibit or augment an inflammatory response
MX9602993A (es) Hormona del crecimiento humano.
AU6020099A (en) Methods for treatment of multiple sclerosis using peptide analogs of human myelin basic protein
HK1005807A1 (en) Mpl ligand analogs
NZ503235A (en) Amino-terminally truncated RANTES as chemokine antagonists
IL75963A0 (en) Interferon derivatives,their preparation and pharmaceutical compositions containing them
NZ289153A (en) Streptogramines and their preparation by mutasynthesis; medicaments; nucleotide sequences and polypeptides from their expression; recombinant dna
HUT58765A (en) Process for producing peptide compounds and pharmaceutical compositions containing them as active components
ATE363488T1 (de) Zusammensetzungen von stammzellfaktor (scf)- analogen und auf diese bezogene verfahren
EP0704527A3 (en) DNA sequences encoding insulin precursors and process for the preparation of insulin
MY102593A (en) Antigents of plasmodium falciparum
EP0367641A3 (en) Lymphokines, dna sequences encoding these lymphokines and pharmaceutical compositions containing these lymphokines
SE9503379D0 (sv) A modified GAD, a method for producing a modified GAD, a method for supplying a modified GAD, a peptide and the use of an ordinary and/or a modified GAD
TW368505B (en) A process for preparing cardiodilatin fragments; highly purified cardiodilatin fragments and intermediate products for the preparation of same

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20100213