HK1005722A1 - New benzene derivatives having (ngf) production-promoting activity - Google Patents
New benzene derivatives having (ngf) production-promoting activityInfo
- Publication number
- HK1005722A1 HK1005722A1 HK98104826A HK98104826A HK1005722A1 HK 1005722 A1 HK1005722 A1 HK 1005722A1 HK 98104826 A HK98104826 A HK 98104826A HK 98104826 A HK98104826 A HK 98104826A HK 1005722 A1 HK1005722 A1 HK 1005722A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- group
- amino group
- substituted
- formula
- benzene derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/36—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/56—Ring systems containing bridged rings
- C07C2603/58—Ring systems containing bridged rings containing three rings
- C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
- C07C2603/74—Adamantanes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2706091 | 1991-02-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1005722A1 true HK1005722A1 (en) | 1999-01-22 |
Family
ID=12210527
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK98104826A HK1005722A1 (en) | 1991-02-21 | 1998-06-03 | New benzene derivatives having (ngf) production-promoting activity |
Country Status (16)
Country | Link |
---|---|
US (2) | US5643925A (de) |
EP (1) | EP0501656B1 (de) |
JP (1) | JPH05112515A (de) |
KR (1) | KR920016406A (de) |
CN (1) | CN1036064C (de) |
AT (1) | ATE148098T1 (de) |
CA (1) | CA2061557A1 (de) |
CZ (1) | CZ50092A3 (de) |
DE (1) | DE69216873T2 (de) |
DK (1) | DK0501656T3 (de) |
ES (1) | ES2099206T3 (de) |
GR (1) | GR3022594T3 (de) |
HK (1) | HK1005722A1 (de) |
HU (1) | HUT64012A (de) |
IE (1) | IE920538A1 (de) |
RU (1) | RU2042663C1 (de) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5993856A (en) * | 1997-01-24 | 1999-11-30 | Femmepharma | Pharmaceutical preparations and methods for their administration |
GB2349880A (en) * | 1999-05-10 | 2000-11-15 | Secr Defence | (Thio)morpholinium salts having SHG activity |
US6348648B1 (en) | 1999-11-23 | 2002-02-19 | Harry Connick, Jr. | System and method for coordinating music display among players in an orchestra |
WO2001076580A1 (en) * | 2000-04-11 | 2001-10-18 | Takara Bio Inc. | Remedies |
DE10115994A1 (de) * | 2001-03-30 | 2002-10-10 | Wella Ag | (p-Amino-hydroxyphenyl)acrylamid-Derivate und diese Verbindungen enthaltende Färbemittel |
PL373484A1 (en) * | 2001-12-10 | 2005-09-05 | Amgen Inc. | Vanilloid receptor ligands and their use in treatments |
KR100459917B1 (ko) * | 2001-12-14 | 2004-12-03 | (주)바이오뉴트리젠 | 페놀릭산 유도체 및 이를 포함하는 혈중 지질 농도 관련질환의 예방 및 치료용 조성물 |
GB0312609D0 (en) | 2003-06-02 | 2003-07-09 | Astrazeneca Ab | Novel compounds |
SE0302139D0 (sv) * | 2003-07-28 | 2003-07-28 | Astrazeneca Ab | Novel compounds |
JP2006008642A (ja) * | 2004-06-29 | 2006-01-12 | Sumitomo Bakelite Co Ltd | アミノフェノール化合物、熱硬化性化合物およびその製造法 |
US7652041B2 (en) * | 2005-01-14 | 2010-01-26 | Millennium Pharmaceuticals, Inc. | Cinnamide and hydrocinnamide derivatives with kinase inhibitory activity |
US8546451B2 (en) | 2005-11-28 | 2013-10-01 | Gtx, Inc. | Estrogen receptor ligands and methods of use thereof |
US8637706B2 (en) | 2005-11-28 | 2014-01-28 | Gtx, Inc. | Nuclear receptor binding agents |
US9409856B2 (en) | 2005-11-28 | 2016-08-09 | Gtx, Inc. | Estrogen receptor ligands and methods of use thereof |
US8158828B2 (en) | 2005-11-28 | 2012-04-17 | Gtx, Inc. | Nuclear receptor binding agents |
WO2008114002A1 (en) * | 2007-03-22 | 2008-09-25 | Astrazeneca Ab | Quinoline derivatives for the treatment of inflammatory diseases |
PE20091036A1 (es) | 2007-11-30 | 2009-08-15 | Astrazeneca Ab | Derivado de quinolina como antagonista del receptor p2x7 |
US9624161B2 (en) | 2009-02-23 | 2017-04-18 | Gtx, Inc. | Estrogen receptor ligands and methods of use thereof |
US9427418B2 (en) | 2009-02-23 | 2016-08-30 | Gtx, Inc. | Estrogen receptor ligands and methods of use thereof |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3147261A (en) * | 1962-05-24 | 1964-09-01 | Robert R Mod | Nu-acyl-nu'-methylpiperazines |
GB1052308A (de) * | 1964-08-25 | |||
GB8417194D0 (en) * | 1984-07-05 | 1984-08-08 | Boots Co Plc | Therapeutic agents |
NZ228329A (en) * | 1988-03-18 | 1991-12-23 | Mitsui Toatsu Chemicals | Catechol derivatives and pharmaceutical compositions thereof |
JPH02104568A (ja) * | 1988-06-22 | 1990-04-17 | Yoshitomi Pharmaceut Ind Ltd | 神経成長因子産生促進作用剤 |
PT94121A (pt) * | 1989-05-23 | 1991-02-08 | Sankyo Co | Processo para a preparacao de derivados fenol para promover o factor de crescimento do nervo humano |
JP2761048B2 (ja) * | 1989-08-25 | 1998-06-04 | 三共株式会社 | 神経成長因子産生促進剤 |
-
1992
- 1992-02-18 ES ES92301326T patent/ES2099206T3/es not_active Expired - Lifetime
- 1992-02-18 DE DE69216873T patent/DE69216873T2/de not_active Expired - Fee Related
- 1992-02-18 AT AT92301326T patent/ATE148098T1/de active
- 1992-02-18 EP EP92301326A patent/EP0501656B1/de not_active Expired - Lifetime
- 1992-02-18 DK DK92301326.2T patent/DK0501656T3/da active
- 1992-02-18 US US07/837,491 patent/US5643925A/en not_active Expired - Fee Related
- 1992-02-20 CZ CS92500A patent/CZ50092A3/cs unknown
- 1992-02-20 IE IE053892A patent/IE920538A1/en not_active Application Discontinuation
- 1992-02-20 RU SU925011163A patent/RU2042663C1/ru active
- 1992-02-20 CA CA002061557A patent/CA2061557A1/en not_active Abandoned
- 1992-02-21 HU HU9200579A patent/HUT64012A/hu unknown
- 1992-02-21 JP JP4035254A patent/JPH05112515A/ja active Pending
- 1992-02-21 CN CN92101074A patent/CN1036064C/zh not_active Expired - Fee Related
- 1992-02-21 KR KR1019920002675A patent/KR920016406A/ko not_active Application Discontinuation
-
1995
- 1995-04-24 US US08/427,664 patent/US5614521A/en not_active Expired - Fee Related
-
1997
- 1997-02-19 GR GR970400279T patent/GR3022594T3/el unknown
-
1998
- 1998-06-03 HK HK98104826A patent/HK1005722A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CA2061557A1 (en) | 1992-08-22 |
RU2042663C1 (ru) | 1995-08-27 |
IE920538A1 (en) | 1992-08-26 |
KR920016406A (ko) | 1992-09-24 |
HU9200579D0 (en) | 1992-05-28 |
ATE148098T1 (de) | 1997-02-15 |
US5643925A (en) | 1997-07-01 |
EP0501656B1 (de) | 1997-01-22 |
EP0501656A2 (de) | 1992-09-02 |
CN1064273A (zh) | 1992-09-09 |
US5614521A (en) | 1997-03-25 |
EP0501656A3 (en) | 1993-03-03 |
DE69216873D1 (de) | 1997-03-06 |
DK0501656T3 (da) | 1997-07-21 |
DE69216873T2 (de) | 1997-08-21 |
CN1036064C (zh) | 1997-10-08 |
CZ50092A3 (en) | 1993-03-17 |
GR3022594T3 (en) | 1997-05-31 |
HUT64012A (en) | 1993-11-29 |
ES2099206T3 (es) | 1997-05-16 |
JPH05112515A (ja) | 1993-05-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1005722A1 (en) | New benzene derivatives having (ngf) production-promoting activity | |
HU9600924D0 (en) | Aromatic hydroxamic acid compounds, their production and use | |
AU8249391A (en) | Sulfonamide derivatives | |
AU6520998A (en) | 1,4-substituted cyclic amine derivatives | |
AU1282495A (en) | Anthranilic acid derivative | |
ATE138069T1 (de) | Schwefel enthaltende kondensierte pyrimidinderivate, ihre herstellung und verwendung | |
MY101268A (en) | Naphthalene derivatives, process for the preparation thereof and pharmaceutical composition containing same | |
HUT52059A (en) | Process for producing pharmaceutical compositions and new quinoline derivatives as a group of active components | |
EP0291917A3 (en) | Novel oxetanocins | |
AU5474294A (en) | Quinoline or quinazoline derivatives, their production and use | |
NO930783L (no) | Kondenserte heterocykliske ketonderivater deres fremstilling og anveendelse | |
EP0333154A3 (de) | Verfahren zur Herstellung von Cephemderivaten und ihren Zwischenverbindungen | |
CA2226406A1 (en) | Novel pyridone carboxylic acid derivatives | |
AU2692792A (en) | Oxazolidone derivative | |
ES8604604A1 (es) | Un procedimiento para la produccion de 3,3",4"-tri-o-acilespiramicina i"-. | |
DE3586649T2 (de) | Verwendung von spergualinderivaten zur herstellung von arzneimitteln mit immunodepressiver wirkung. | |
AU3484589A (en) | Azacyclic carboxylic acid derivatives, their preparation and use | |
IE893211L (en) | Benzoxazepinone Process | |
NZ332245A (en) | Substituted benzo-oxazolol carboxylic acid derivatives, process for their production and medicaments containing them | |
MY104689A (en) | Amine salts of 1,4,2-oxazaphospholidine-4-acetic acid, 2-alkoxy-2-oxides. | |
EP0449011A3 (en) | Stereoselective process for the preparation of 2-amino-ethanol derivatives having a central analgesic activity and intermediates thereof | |
AU7453487A (en) | Cis and trans stilbenes |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |