GT201400213A - Inhibidores de diacilglicerol aciltransferasa 2 - Google Patents

Inhibidores de diacilglicerol aciltransferasa 2

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Publication number
GT201400213A
GT201400213A GT201400213A GT201400213A GT201400213A GT 201400213 A GT201400213 A GT 201400213A GT 201400213 A GT201400213 A GT 201400213A GT 201400213 A GT201400213 A GT 201400213A GT 201400213 A GT201400213 A GT 201400213A
Authority
GT
Guatemala
Prior art keywords
diacilglicerol
aciltransferasa
inhibitors
imidazo
aciltransferase
Prior art date
Application number
GT201400213A
Other languages
English (en)
Inventor
Ahn Kay
Boehm Markus
Cabral Shawn
Philip A Carpino
Futatsugi Kentaro
Hepworth David
Daniel W Kung
Orr Suvi
Wang Jian
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48428540&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GT201400213(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Publication of GT201400213A publication Critical patent/GT201400213A/es

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    • C—CHEMISTRY; METALLURGY
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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Abstract

LOS DERIVADOS DE PURINA, 3H-IMIDAZO [4,5-B] PIRIMIDINA Y 1H- IMIDAZO [4,5-D] PIRAZINA DE FÓRMULA I QUE INHIBEN LA ACTIVIDAD DE LA DIACILGLICEROL ACILTRANSFERASA 2 (DGAT2) Y SUS USOS EN EL TRATAMIENTO DE ENFERMEDADES AL MISMO VINCULADO EN ANIMALES SE DESCRIBEN EN ESTE DOCUMENTO.
GT201400213A 2012-04-06 2014-10-06 Inhibidores de diacilglicerol aciltransferasa 2 GT201400213A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261621144P 2012-04-06 2012-04-06

Publications (1)

Publication Number Publication Date
GT201400213A true GT201400213A (es) 2015-06-02

Family

ID=48428540

Family Applications (1)

Application Number Title Priority Date Filing Date
GT201400213A GT201400213A (es) 2012-04-06 2014-10-06 Inhibidores de diacilglicerol aciltransferasa 2

Country Status (27)

Country Link
US (1) US9296745B2 (es)
EP (1) EP2834238B1 (es)
JP (1) JP2015515472A (es)
KR (1) KR20140137404A (es)
CN (1) CN104334557A (es)
AP (1) AP2014007953A0 (es)
AU (1) AU2013245353A1 (es)
CA (1) CA2869587A1 (es)
CL (1) CL2014002541A1 (es)
CO (1) CO7160030A2 (es)
CR (1) CR20140468A (es)
CU (1) CU20140115A7 (es)
DO (1) DOP2014000225A (es)
EA (1) EA201400990A1 (es)
EC (1) ECSP14021251A (es)
GT (1) GT201400213A (es)
HK (1) HK1206735A1 (es)
IL (1) IL234928A0 (es)
MA (1) MA37385B1 (es)
MD (1) MD20140103A2 (es)
MX (1) MX2014011373A (es)
NI (1) NI201400120A (es)
PE (1) PE20142164A1 (es)
PH (1) PH12014502057A1 (es)
SG (1) SG11201405477XA (es)
TN (1) TN2014000419A1 (es)
WO (1) WO2013150416A1 (es)

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JP2015515472A (ja) 2015-05-28
CN104334557A (zh) 2015-02-04
CO7160030A2 (es) 2015-01-15
CR20140468A (es) 2014-11-17
MA201637385A2 (fr) 2016-03-31
US20150087585A1 (en) 2015-03-26
TN2014000419A1 (fr) 2016-03-30
AP2014007953A0 (en) 2014-09-30
MA37385B1 (fr) 2019-09-30
MD20140103A2 (ro) 2015-01-31
US9296745B2 (en) 2016-03-29
NI201400120A (es) 2015-11-18
EP2834238B1 (en) 2017-02-01
SG11201405477XA (en) 2014-11-27
EA201400990A1 (ru) 2015-01-30
DOP2014000225A (es) 2014-11-30
KR20140137404A (ko) 2014-12-02
AU2013245353A1 (en) 2014-09-25
MA37385A3 (fr) 2016-12-30
HK1206735A1 (en) 2016-01-15
CL2014002541A1 (es) 2015-01-16
PH12014502057A1 (en) 2014-12-10
CU20140115A7 (es) 2014-11-27
ECSP14021251A (es) 2015-09-30
CA2869587A1 (en) 2013-10-10
WO2013150416A1 (en) 2013-10-10
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EP2834238A1 (en) 2015-02-11
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