GT201100026A - Compuestos de fenantrenona, composiciones y métodos - Google Patents
Compuestos de fenantrenona, composiciones y métodosInfo
- Publication number
- GT201100026A GT201100026A GT201100026A GT201100026A GT201100026A GT 201100026 A GT201100026 A GT 201100026A GT 201100026 A GT201100026 A GT 201100026A GT 201100026 A GT201100026 A GT 201100026A GT 201100026 A GT201100026 A GT 201100026A
- Authority
- GT
- Guatemala
- Prior art keywords
- compositions
- compounds
- methods
- fenantrenone
- octahydrophenantrene
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4406—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Transplantation (AREA)
- Dermatology (AREA)
- Ophthalmology & Optometry (AREA)
- Physical Education & Sports Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Pyridine Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
LA PRESENTE INVENCIÓN INCLUYE COMPUESTOS DE 4N-BENCIL-6,7-DIHIDROXI-6-METIL-N-(2-METILPIRIDIN-3-IL)-10-OXO-7-FENIL-4B,5,6,7,8,8A,9,10-OCTAHIDROFENANTRENO-2-CARBOXAMIDA O UNA DE SUS SALES FARMACÉUTICAMENTE ACEPTABLE QUE SON MODULADORES DEL RECEPTOR DE GLUCOCORTICOIDE. ADEMÁS DE COMPOSICIONES Y MÉTODOS DE USO DE DICHOS COMPUESTOS Y COMPOSICIONES PARA AFECCIONES RELACIONADAS CON LA INFLAMACIÓN.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8409508P | 2008-07-28 | 2008-07-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
GT201100026A true GT201100026A (es) | 2013-12-10 |
Family
ID=41037773
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GT201100026A GT201100026A (es) | 2008-07-28 | 2011-01-27 | Compuestos de fenantrenona, composiciones y métodos |
Country Status (39)
Country | Link |
---|---|
US (2) | US8148409B2 (es) |
EP (1) | EP2307375B1 (es) |
JP (1) | JP4823397B1 (es) |
KR (1) | KR101377860B1 (es) |
CN (1) | CN102112446B (es) |
AP (1) | AP2744A (es) |
AR (1) | AR072535A1 (es) |
AU (1) | AU2009278029B2 (es) |
BR (1) | BRPI0917212A2 (es) |
CA (1) | CA2729578C (es) |
CL (1) | CL2011000141A1 (es) |
CO (1) | CO6290761A2 (es) |
CR (1) | CR20110012A (es) |
CU (1) | CU23983B1 (es) |
DK (1) | DK2307375T3 (es) |
DO (1) | DOP2011000029A (es) |
EA (1) | EA018024B1 (es) |
EC (1) | ECSP11010795A (es) |
ES (1) | ES2527137T3 (es) |
GE (1) | GEP20125640B (es) |
GT (1) | GT201100026A (es) |
HK (1) | HK1154245A1 (es) |
HR (1) | HRP20150021T1 (es) |
IL (1) | IL210492A (es) |
MA (1) | MA32512B1 (es) |
MX (1) | MX2011001053A (es) |
NI (1) | NI201100028A (es) |
NZ (1) | NZ590559A (es) |
PE (1) | PE20110559A1 (es) |
PL (1) | PL2307375T3 (es) |
PT (1) | PT2307375E (es) |
RS (1) | RS53747B1 (es) |
SI (1) | SI2307375T1 (es) |
SV (1) | SV2011003821A (es) |
TW (1) | TWI374878B (es) |
UA (1) | UA99198C2 (es) |
UY (1) | UY32011A (es) |
WO (1) | WO2010013158A1 (es) |
ZA (1) | ZA201101520B (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20140015472A (ko) * | 2011-03-15 | 2014-02-06 | 애브비 인코포레이티드 | 핵 호르몬 수용체 조절제 |
TW201422590A (zh) | 2012-09-07 | 2014-06-16 | Abbvie Inc | 雜環核激素受體調節劑 |
EP2935284A4 (en) | 2012-12-21 | 2016-04-27 | Abbvie Inc | HETEROCYCLIC MODULATORS OF HORMONE NUCLEAR RECEPTORS |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AP1542A (en) | 1999-04-30 | 2006-01-31 | Pfizer Prod Inc | Glucocorticoid receptor modulators. |
KR100694685B1 (ko) | 1999-07-30 | 2007-03-13 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 염기성 항생물질ㆍ무기산염의 제조 방법 및 수산염중간체 |
EP1201649B1 (en) | 2000-10-28 | 2006-05-31 | Pfizer Products Inc. | Glucocorticoid receptor modulators |
ES2246292T3 (es) | 2000-10-30 | 2006-02-16 | Pfizer Products Inc. | Moduladores de receptor glucocorticoide. |
WO2004005229A1 (en) | 2002-07-08 | 2004-01-15 | Pfizer Products Inc. | Modulators of the glucocorticoid receptor |
CA2591948C (en) | 2005-01-19 | 2013-11-12 | Rigel Pharmaceuticals, Inc. | Prodrugs of 2,4-pyrimidinediamine compounds and their uses |
GB0613836D0 (en) | 2006-07-13 | 2006-08-23 | Univ Greenwich | New medical use of triazine derivatives |
DK2078026T3 (da) | 2006-11-21 | 2012-04-30 | Rigel Pharmaceuticals Inc | Prodrug-salte af 2, 4-pyrimidinediamine-forbindelser og anvendelser deraf |
KR20090086627A (ko) | 2006-12-05 | 2009-08-13 | 노이로제스엑스, 인코포레이티드 | 프로드러그 및 그것의 제조 및 사용 방법 |
EP2114970B1 (en) * | 2007-02-02 | 2011-08-03 | Pfizer Products Inc. | Tricyclic compounds and their use as glucocorticoid receptor modulators |
AP2411A (en) * | 2007-02-02 | 2012-05-30 | Pfizer Prod Inc | Tricyclic compounds and their use as glucocorticoid receptor modulators |
-
2009
- 2009-07-14 KR KR1020117002134A patent/KR101377860B1/ko not_active IP Right Cessation
- 2009-07-14 CN CN200980129538XA patent/CN102112446B/zh not_active Expired - Fee Related
- 2009-07-14 PL PL09786592T patent/PL2307375T3/pl unknown
- 2009-07-14 UA UAA201100440A patent/UA99198C2/ru unknown
- 2009-07-14 ES ES09786592.7T patent/ES2527137T3/es active Active
- 2009-07-14 EP EP09786592.7A patent/EP2307375B1/en active Active
- 2009-07-14 JP JP2011520622A patent/JP4823397B1/ja not_active Expired - Fee Related
- 2009-07-14 AU AU2009278029A patent/AU2009278029B2/en not_active Ceased
- 2009-07-14 DK DK09786592.7T patent/DK2307375T3/en active
- 2009-07-14 MX MX2011001053A patent/MX2011001053A/es active IP Right Grant
- 2009-07-14 GE GEAP200912074A patent/GEP20125640B/en unknown
- 2009-07-14 BR BRPI0917212A patent/BRPI0917212A2/pt not_active IP Right Cessation
- 2009-07-14 PE PE2011000098A patent/PE20110559A1/es not_active Application Discontinuation
- 2009-07-14 PT PT97865927T patent/PT2307375E/pt unknown
- 2009-07-14 CA CA2729578A patent/CA2729578C/en not_active Expired - Fee Related
- 2009-07-14 EA EA201100080A patent/EA018024B1/ru not_active IP Right Cessation
- 2009-07-14 SI SI200931100T patent/SI2307375T1/sl unknown
- 2009-07-14 NZ NZ590559A patent/NZ590559A/en not_active IP Right Cessation
- 2009-07-14 AP AP2011005562A patent/AP2744A/xx active
- 2009-07-14 RS RS20150019A patent/RS53747B1/en unknown
- 2009-07-14 WO PCT/IB2009/053044 patent/WO2010013158A1/en active Application Filing
- 2009-07-20 US US12/505,932 patent/US8148409B2/en not_active Expired - Fee Related
- 2009-07-27 TW TW098125265A patent/TWI374878B/zh not_active IP Right Cessation
- 2009-07-27 AR ARP090102852A patent/AR072535A1/es unknown
- 2009-07-28 UY UY0001032011A patent/UY32011A/es not_active Application Discontinuation
-
2011
- 2011-01-06 IL IL210492A patent/IL210492A/en not_active IP Right Cessation
- 2011-01-10 CR CR20110012A patent/CR20110012A/es unknown
- 2011-01-21 CL CL2011000141A patent/CL2011000141A1/es unknown
- 2011-01-26 NI NI201100028A patent/NI201100028A/es unknown
- 2011-01-27 GT GT201100026A patent/GT201100026A/es unknown
- 2011-01-27 CO CO11009253A patent/CO6290761A2/es active IP Right Grant
- 2011-01-27 DO DO2011000029A patent/DOP2011000029A/es unknown
- 2011-01-28 MA MA33568A patent/MA32512B1/fr unknown
- 2011-01-28 CU CU2011000020A patent/CU23983B1/es active IP Right Grant
- 2011-01-28 EC EC2011010795A patent/ECSP11010795A/es unknown
- 2011-01-28 SV SV2011003821A patent/SV2011003821A/es unknown
- 2011-02-25 ZA ZA2011/01520A patent/ZA201101520B/en unknown
- 2011-08-04 HK HK11108133.8A patent/HK1154245A1/en not_active IP Right Cessation
-
2012
- 2012-02-27 US US13/406,446 patent/US8552035B2/en not_active Expired - Fee Related
-
2015
- 2015-01-09 HR HRP20150021AT patent/HRP20150021T1/hr unknown
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