GT200300102A - DERIVATIVES OF HIDROXI TETRAHIDRO-NAFTALENIL UREA - Google Patents

DERIVATIVES OF HIDROXI TETRAHIDRO-NAFTALENIL UREA

Info

Publication number
GT200300102A
GT200300102A GT200300102A GT200300102A GT200300102A GT 200300102 A GT200300102 A GT 200300102A GT 200300102 A GT200300102 A GT 200300102A GT 200300102 A GT200300102 A GT 200300102A GT 200300102 A GT200300102 A GT 200300102A
Authority
GT
Guatemala
Prior art keywords
derivatives
naftalenil
tetrahidro
hidroxi
urea
Prior art date
Application number
GT200300102A
Other languages
Spanish (es)
Inventor
Takeshi Yura
Muneto Mogi
Klaus Urbahns
Hiroshi Fujishima
Tsutomu Masuda
Toshiya Moriwaki
Nagahiro Yoshida
Toshio Kokubo
Masahiro Shiroo
Masaomi Tajimi
Yasuhiro Tsukimi
Noriyuki Yamamoto
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GT200300102A publication Critical patent/GT200300102A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/32—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/40—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups

Abstract

LA PRESENTE INVENCION SE REFIERE A DERIVADOS DE HIDROXITETRAHIDRONAFTALENILUREA DE FORMULA GENERAL I EN DONDE X,Z1,Z2, SON GRUPOS FUNCIONALES DESCRITOS EN LA SOLICITUD. ESTOS COMPUESTOS TIENEN ACTIVIDAD ANTAGONISTA DEL RECEPTOR DE VANILLOIDES (VR) POR LO QUE SON DE UTILIDAD EN UNA AMPLIA VARIEDAD DE CASOS TALES COMO VEJIGA SUPERACTIVA, DOLOR CRONICO, DOLOR NEUROPATICO, DOLOR POSTOPERATORIO, NEURALGIA, ENTRE OTROS DESCRITOS EN LA SOLICITUD.THIS INVENTION REFERS TO DERIVATIVES OF HYDROXYTHETRAHYDRONAFTALENILUREA OF GENERAL FORMULA I WHERE X, Z1, Z2, ARE FUNCTIONAL GROUPS DESCRIBED IN THE APPLICATION. THESE COMPOUNDS HAVE ANALOGONIST ACTIVITY OF THE VANILLOID RECEIVER (VR) SO THEY ARE USEFUL IN A LARGE VARIETY OF SUCH CASES AS A SUPERACTIVE BLADDER, CHRONIC PAIN, NEUROPATHIC PAIN, POSTOPERATIVE PAIN, ENCRYPTION ENCRYPTION.

GT200300102A 2002-05-08 2003-05-05 DERIVATIVES OF HIDROXI TETRAHIDRO-NAFTALENIL UREA GT200300102A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0210512.0A GB0210512D0 (en) 2002-05-08 2002-05-08 Tetrahydro-napthalene derivatives

Publications (1)

Publication Number Publication Date
GT200300102A true GT200300102A (en) 2004-03-17

Family

ID=9936269

Family Applications (1)

Application Number Title Priority Date Filing Date
GT200300102A GT200300102A (en) 2002-05-08 2003-05-05 DERIVATIVES OF HIDROXI TETRAHIDRO-NAFTALENIL UREA

Country Status (13)

Country Link
KR (1) KR101000688B1 (en)
AR (1) AR039983A1 (en)
CU (1) CU23422B7 (en)
DO (1) DOP2003000642A (en)
EC (1) ECSP045413A (en)
GB (2) GB0210512D0 (en)
GT (1) GT200300102A (en)
MA (1) MA30728B1 (en)
MY (1) MY155011A (en)
PE (1) PE20040363A1 (en)
PT (1) PT1506167E (en)
UA (1) UA77301C2 (en)
ZA (1) ZA200408993B (en)

Also Published As

Publication number Publication date
KR20040108784A (en) 2004-12-24
PE20040363A1 (en) 2004-07-03
ECSP045413A (en) 2005-01-03
DOP2003000642A (en) 2003-11-15
KR101000688B1 (en) 2010-12-10
PT1506167E (en) 2007-12-10
GB0227262D0 (en) 2002-12-31
AR039983A1 (en) 2005-03-09
MA30728B1 (en) 2009-10-01
MY155011A (en) 2015-08-28
UA77301C2 (en) 2006-11-15
GB0210512D0 (en) 2002-06-19
ZA200408993B (en) 2006-01-25
CU23422B7 (en) 2009-09-08

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