GT198303012A - 5-(alquilo inferior)-1,6 naftiridin-2(1h) onas, sus composi ciones cardiotonicas y su preparacion - Google Patents
5-(alquilo inferior)-1,6 naftiridin-2(1h) onas, sus composi ciones cardiotonicas y su preparacionInfo
- Publication number
- GT198303012A GT198303012A GT198303012A GT198303012A GT198303012A GT 198303012 A GT198303012 A GT 198303012A GT 198303012 A GT198303012 A GT 198303012A GT 198303012 A GT198303012 A GT 198303012A GT 198303012 A GT198303012 A GT 198303012A
- Authority
- GT
- Guatemala
- Prior art keywords
- onas
- naftiridin
- preparation
- lower rent
- cardiotonic compositions
- Prior art date
Links
- 230000003177 cardiotonic effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
- C07D213/85—Nitriles in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/404,454 US4415580A (en) | 1982-08-02 | 1982-08-02 | Certain 2-(1H)-pyridinones cardiotonic compositions containing same and method of using same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GT198303012A true GT198303012A (es) | 1985-01-19 |
Family
ID=23599673
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GT198303012A GT198303012A (es) | 1982-08-02 | 1983-07-29 | 5-(alquilo inferior)-1,6 naftiridin-2(1h) onas, sus composi ciones cardiotonicas y su preparacion |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US4415580A (enExample) |
| EP (2) | EP0204335A3 (enExample) |
| JP (1) | JPS5944387A (enExample) |
| KR (1) | KR870000959B1 (enExample) |
| AT (1) | ATE29883T1 (enExample) |
| AU (1) | AU561679B2 (enExample) |
| DE (1) | DE3373813D1 (enExample) |
| DK (2) | DK350983A (enExample) |
| EG (1) | EG16284A (enExample) |
| ES (2) | ES8605515A1 (enExample) |
| FI (1) | FI74001C (enExample) |
| GR (1) | GR79370B (enExample) |
| GT (1) | GT198303012A (enExample) |
| IL (1) | IL69325A (enExample) |
| MY (1) | MY102475A (enExample) |
| NO (1) | NO160077C (enExample) |
| NZ (1) | NZ204969A (enExample) |
| PH (1) | PH19871A (enExample) |
| PT (1) | PT77118B (enExample) |
| ZA (1) | ZA835446B (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4595762A (en) * | 1982-08-25 | 1986-06-17 | Sterling Drug Inc. | 5-α-bromoalkanoyl-2-oxo-3-pyridinecarbonitriles |
| US4532247A (en) * | 1983-08-08 | 1985-07-30 | Sterling Drug Inc. | 5-(Hydroxyalkyl or alkanoyloxymethyl)-1,6-naphthyridin-2(1H)-one and cardiotonic use thereof |
| US4560691A (en) * | 1984-07-13 | 1985-12-24 | Sterling Drug Inc. | 5-(Phenyl)-1,6-naphthyridin-2(1H)-ones, their cardiotonic use and preparation |
| US4657919A (en) * | 1984-08-03 | 1987-04-14 | E. I. Du Pont De Nemours & Co. | Pyridone esters as inotropic agents |
| DE3431303A1 (de) * | 1984-08-25 | 1986-02-27 | Goedecke Ag | 1,6-naphthyridin-derivate, verfahren zu deren herstellung und deren verwendung |
| US4650806A (en) * | 1985-01-14 | 1987-03-17 | Sterling Drug Inc. | Cardiotonic 5-(heterylcarbonyl)-pyridones |
| US4567186A (en) * | 1985-01-14 | 1986-01-28 | Sterling Drug Inc. | 5-Heteryl-1,6-naphthyridin-2(1H)-ones, cardiotonic use thereof and intermediates therefor |
| US4697021A (en) * | 1985-01-28 | 1987-09-29 | Sterling Drug Inc. | 1,6-dihydro-6-oxo-3-pyridinecarbonitriles, intermediates for cardiotonic agents |
| US4657915A (en) * | 1985-01-28 | 1987-04-14 | Sterling Drug Inc. | 1,6-naphthyridine-2(1H)-ones and their use as cardiotonic agents |
| US4634772A (en) * | 1985-01-28 | 1987-01-06 | Sterling Drug Inc. | 2-[2-(di-lower-alkylamino)-1-propenyl]-6-methoxy-3-pyridinecarbonitriles, intermediates for cardiotonic agents |
| US4716170A (en) * | 1985-01-28 | 1987-12-29 | Sterling Drug Inc. | 5-[1H-(5-membered-N-aromatic heteryl)-1-yl]-1,6-naphthyridin-2(1H)-ones and their cardiotonic use |
| NZ214837A (en) * | 1985-01-28 | 1988-10-28 | Sterling Drug Inc | 5-substituted 1,6 naphthyridin-2(1h)-ones |
| ZA985870B (en) | 1997-07-15 | 1999-01-27 | Dainippon Pharmaceutical Co | 5-substituted-3-oxadiazolyl-1, 6-naphthyridin-2(1H)-one derivatives |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4072746A (en) * | 1975-10-14 | 1978-02-07 | Sterling Drug Inc. | 3-Amino-5-(pyridinyl)-2(1H)-pyridinones |
| US4363911A (en) * | 1981-09-03 | 1982-12-14 | Sterling Drug Inc. | 1,2-Dihydro-6-[2-(dimethylamino)ethenyl]-2-oxo-5-(pyridinyl) nicotinonitriles |
-
1982
- 1982-08-02 US US06/404,454 patent/US4415580A/en not_active Expired - Fee Related
-
1983
- 1983-07-20 NZ NZ204969A patent/NZ204969A/xx unknown
- 1983-07-25 IL IL69325A patent/IL69325A/xx unknown
- 1983-07-26 ZA ZA835446A patent/ZA835446B/xx unknown
- 1983-07-26 AU AU17291/83A patent/AU561679B2/en not_active Ceased
- 1983-07-27 PT PT77118A patent/PT77118B/pt not_active IP Right Cessation
- 1983-07-28 AT AT83107465T patent/ATE29883T1/de active
- 1983-07-28 EP EP86107627A patent/EP0204335A3/en not_active Ceased
- 1983-07-28 EP EP83107465A patent/EP0101952B1/en not_active Expired
- 1983-07-28 DE DE8383107465T patent/DE3373813D1/de not_active Expired
- 1983-07-28 FI FI832739A patent/FI74001C/fi not_active IP Right Cessation
- 1983-07-28 GR GR72074A patent/GR79370B/el unknown
- 1983-07-29 GT GT198303012A patent/GT198303012A/es unknown
- 1983-08-01 DK DK350983A patent/DK350983A/da not_active Application Discontinuation
- 1983-08-01 KR KR1019830003601A patent/KR870000959B1/ko not_active Expired
- 1983-08-01 NO NO832784A patent/NO160077C/no unknown
- 1983-08-01 ES ES524642A patent/ES8605515A1/es not_active Expired
- 1983-08-02 EG EG480/83A patent/EG16284A/xx active
- 1983-08-02 JP JP58141813A patent/JPS5944387A/ja active Pending
- 1983-08-02 PH PH29344A patent/PH19871A/en unknown
-
1984
- 1984-03-15 ES ES530632A patent/ES530632A0/es active Granted
-
1987
- 1987-09-29 MY MYPI87002238A patent/MY102475A/en unknown
-
1990
- 1990-07-25 DK DK176890A patent/DK176890D0/da not_active IP Right Cessation
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