GR920300106T1 - Antihypercholesterolemics. - Google Patents
Antihypercholesterolemics.Info
- Publication number
- GR920300106T1 GR920300106T1 GR920300106T GR920300106T GR920300106T1 GR 920300106 T1 GR920300106 T1 GR 920300106T1 GR 920300106 T GR920300106 T GR 920300106T GR 920300106 T GR920300106 T GR 920300106T GR 920300106 T1 GR920300106 T1 GR 920300106T1
- Authority
- GR
- Greece
- Prior art keywords
- antihypercholesterolemics
- image
- compounds
- useful
- structural formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
- C12P1/02—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using fungi
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
- C12N1/145—Fungal isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P9/00—Preparation of organic compounds containing a metal or atom other than H, N, C, O, S or halogen
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/645—Fungi ; Processes using fungi
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49673190A | 1990-03-21 | 1990-03-21 | |
US49674990A | 1990-03-21 | 1990-03-21 | |
US07/496,742 US5096923A (en) | 1990-03-21 | 1990-03-21 | Novel squalene synthetase inhibitors |
US07/626,071 US5053425A (en) | 1990-03-21 | 1990-12-11 | Novel anti-fungal compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
GR920300106T1 true GR920300106T1 (en) | 1993-02-17 |
Family
ID=27504381
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR920300106T GR920300106T1 (en) | 1990-03-21 | 1993-02-17 | Antihypercholesterolemics. |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP0450812B1 (el) |
JP (1) | JPH04279589A (el) |
KR (1) | KR910016931A (el) |
AT (1) | ATE104982T1 (el) |
AU (1) | AU640755B2 (el) |
CA (1) | CA2038517A1 (el) |
CS (1) | CS71991A2 (el) |
DE (2) | DE450812T1 (el) |
DK (1) | DK0450812T3 (el) |
ES (1) | ES2052463T1 (el) |
GR (1) | GR920300106T1 (el) |
HU (1) | HUT61555A (el) |
IE (1) | IE910924A1 (el) |
IL (1) | IL97535A0 (el) |
NO (1) | NO911121L (el) |
NZ (1) | NZ237448A (el) |
PT (1) | PT97077A (el) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL97251A0 (en) * | 1990-03-21 | 1992-05-25 | Merck & Co Inc | Antihypercholesterolemic 2,8-dioxabicyclo(3,2,1)octane derivatives,their preparation and pharmaceutical compositions containing them |
GB9100437D0 (en) * | 1991-01-09 | 1991-02-20 | Glaxo Group Ltd | Chemical compounds |
GB9105152D0 (en) * | 1991-03-12 | 1991-04-24 | Glaxo Group Ltd | Chemical compounds |
US5256689A (en) * | 1991-05-10 | 1993-10-26 | Merck & Co., Inc. | Cholesterol lowering compounds |
CA2109523A1 (en) * | 1991-05-10 | 1992-11-26 | Robert M. Burk | Novel cholesterol lowering compounds |
US5506262A (en) * | 1991-05-10 | 1996-04-09 | Merck & Co., Inc. | Cholesterol lowering compounds |
US5200342A (en) * | 1991-06-14 | 1993-04-06 | Merck & Co., Inc. | Squalene synthetase inhibitors and processes therefrom |
US5250424A (en) * | 1991-06-14 | 1993-10-05 | Merck & Co., Inc. | Processes for preparing novel squalene synthetase inhibitors |
CA2071723A1 (en) * | 1991-06-27 | 1992-12-28 | Gerald F. Bills | Culture of exserohilum rostratum and processes therefrom |
EP0524677A1 (en) * | 1991-07-16 | 1993-01-27 | Glaxo Group Limited | Cyclic ketal derivatives |
EP0598021A1 (en) * | 1991-08-07 | 1994-05-25 | Merck & Co. Inc. | Novel cholesterol lowering compound |
GB9121380D0 (en) * | 1991-10-08 | 1991-11-20 | Glaxo Group Ltd | Chemical compounds |
GB2261374A (en) * | 1991-11-15 | 1993-05-19 | Merck & Co Inc | Inhibitors of farnesyl protein transferase as anti-cancer agents |
US5252471A (en) * | 1992-03-09 | 1993-10-12 | Merck & Co., Inc. | Directed biosynthesis of cholesterol lowering compounds |
WO1993017557A1 (en) * | 1992-03-09 | 1993-09-16 | Merck & Co., Inc. | Cholesterol lowering compounds produced by directed biosynthesis |
US5294627A (en) * | 1992-08-27 | 1994-03-15 | Merck & Co., Inc. | Directed biosynthesis of biologically active compounds |
GB9205136D0 (en) * | 1992-03-10 | 1992-04-22 | Glaxo Group Ltd | Chemical compounds |
GB9205140D0 (en) * | 1992-03-10 | 1992-04-22 | Glaxo Group Ltd | Chemical compounds |
EP0568946A1 (en) * | 1992-05-08 | 1993-11-10 | Takeda Chemical Industries, Ltd. | Compound TAN-1607A, its derivatives, their production, and use thereof |
US5260215A (en) * | 1992-07-20 | 1993-11-09 | Merck & Co., Inc. | Fungal microorganism ATCC 74167 capable of producing cholesterol lowering compounds |
US5283256A (en) * | 1992-07-22 | 1994-02-01 | Merck & Co., Inc. | Cholesterol-lowering agents |
US5322855A (en) * | 1992-10-19 | 1994-06-21 | Merck & Co., Inc. | Cholesterol lowering compounds |
US5447717A (en) * | 1993-02-25 | 1995-09-05 | Merck & Co., Inc. | Cholesterol-lowering agents |
US5430055A (en) * | 1994-04-08 | 1995-07-04 | Pfizer Inc. | Inhibitor of squalene synthase |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4276216A (en) * | 1980-07-31 | 1981-06-30 | Ortho Pharmaceutical Corporation | Synthesis of dioxabicyclo[3.2.1]octanes and oxepanes |
IL97251A0 (en) * | 1990-03-21 | 1992-05-25 | Merck & Co Inc | Antihypercholesterolemic 2,8-dioxabicyclo(3,2,1)octane derivatives,their preparation and pharmaceutical compositions containing them |
-
1991
- 1991-03-13 IL IL97535A patent/IL97535A0/xx unknown
- 1991-03-15 NZ NZ237448A patent/NZ237448A/en unknown
- 1991-03-18 CA CA002038517A patent/CA2038517A1/en not_active Abandoned
- 1991-03-19 CS CS91719A patent/CS71991A2/cs unknown
- 1991-03-19 PT PT97077A patent/PT97077A/pt not_active Application Discontinuation
- 1991-03-20 IE IE092491A patent/IE910924A1/en unknown
- 1991-03-20 HU HU91930A patent/HUT61555A/hu unknown
- 1991-03-20 AU AU73683/91A patent/AU640755B2/en not_active Ceased
- 1991-03-20 JP JP3081767A patent/JPH04279589A/ja active Pending
- 1991-03-20 NO NO91911121A patent/NO911121L/no unknown
- 1991-03-21 DE DE199191302458T patent/DE450812T1/de active Pending
- 1991-03-21 ES ES91302458T patent/ES2052463T1/es active Pending
- 1991-03-21 KR KR1019910004438A patent/KR910016931A/ko not_active Application Discontinuation
- 1991-03-21 DK DK91302458.4T patent/DK0450812T3/da active
- 1991-03-21 EP EP91302458A patent/EP0450812B1/en not_active Expired - Lifetime
- 1991-03-21 AT AT9191302458T patent/ATE104982T1/de active
- 1991-03-21 DE DE69101802T patent/DE69101802T2/de not_active Expired - Fee Related
-
1993
- 1993-02-17 GR GR920300106T patent/GR920300106T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
DE69101802T2 (de) | 1994-10-27 |
HUT61555A (en) | 1993-01-28 |
NO911121L (no) | 1991-09-23 |
DE69101802D1 (de) | 1994-06-01 |
IE910924A1 (en) | 1991-09-25 |
AU7368391A (en) | 1993-01-28 |
NZ237448A (en) | 1993-11-25 |
HU910930D0 (en) | 1991-10-28 |
PT97077A (pt) | 1991-11-29 |
NO911121D0 (no) | 1991-03-20 |
AU640755B2 (en) | 1993-09-02 |
KR910016931A (ko) | 1991-11-05 |
CS71991A2 (en) | 1991-11-12 |
EP0450812A1 (en) | 1991-10-09 |
IL97535A0 (en) | 1992-06-21 |
ATE104982T1 (de) | 1994-05-15 |
CA2038517A1 (en) | 1991-09-22 |
DE450812T1 (de) | 1992-11-26 |
ES2052463T1 (es) | 1994-07-16 |
DK0450812T3 (da) | 1994-06-06 |
JPH04279589A (ja) | 1992-10-05 |
EP0450812B1 (en) | 1994-04-27 |
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