GR890100824A - Χημική παρασκευή νουκλεοτιδικών ανιχνευτών υψηλής ειδικής ενεργότητας. - Google Patents

Χημική παρασκευή νουκλεοτιδικών ανιχνευτών υψηλής ειδικής ενεργότητας.

Info

Publication number
GR890100824A
GR890100824A GR890100824A GR890100824A GR890100824A GR 890100824 A GR890100824 A GR 890100824A GR 890100824 A GR890100824 A GR 890100824A GR 890100824 A GR890100824 A GR 890100824A GR 890100824 A GR890100824 A GR 890100824A
Authority
GR
Greece
Prior art keywords
nucleotides
chemical preparation
special activity
activity
special
Prior art date
Application number
GR890100824A
Other languages
English (en)
Inventor
Chandler Dr Bahl
Leopoldo Mendoza
Original Assignee
Ortho Diagnostic Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Diagnostic Systems Inc filed Critical Ortho Diagnostic Systems Inc
Publication of GR890100824A publication Critical patent/GR890100824A/el

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Η παρούσα εφεύρεση παρέχει μια διαδικασία για τη χημική σύνθεση ενός σημασμένου νουκλεοτιδικού ανιχνευτή διαμέσου μιας χημικής σύνδεσης ή συνένωσης των δύο συστατικών του ανιχνευτή συγκεκριμένα της αλληλουχίας ημίσεως αναγνώρισης στόχου και του ημίσεως παραγωγής σήματος. ω
GR890100824A 1988-12-16 1989-12-15 Χημική παρασκευή νουκλεοτιδικών ανιχνευτών υψηλής ειδικής ενεργότητας. GR890100824A (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/285,274 US5324829A (en) 1988-12-16 1988-12-16 High specific activity nucleic acid probes having target recognition and signal generating moieties

Publications (1)

Publication Number Publication Date
GR890100824A true GR890100824A (el) 1991-03-15

Family

ID=23093537

Family Applications (1)

Application Number Title Priority Date Filing Date
GR890100824A GR890100824A (el) 1988-12-16 1989-12-15 Χημική παρασκευή νουκλεοτιδικών ανιχνευτών υψηλής ειδικής ενεργότητας.

Country Status (8)

Country Link
US (3) US5324829A (el)
EP (1) EP0373956B1 (el)
JP (1) JPH02245663A (el)
AT (1) ATE125545T1 (el)
CA (1) CA2005557A1 (el)
DE (1) DE68923603T2 (el)
ES (1) ES2076219T3 (el)
GR (1) GR890100824A (el)

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EP0599337B1 (en) * 1992-11-27 2006-03-08 Canon Kabushiki Kaisha Method for detection of nucleic acid and probe therefor
FR2710075B1 (fr) * 1993-09-15 1995-10-27 Bio Merieux Réactif et procédé pour la détection d'une séquence nucléotidique avec amplification de signal.
EP0684239B1 (en) * 1994-05-26 2003-12-10 Canon Kabushiki Kaisha A method for detecting a target substance in a sample, utilizing pyrylium compound
US5871902A (en) * 1994-12-09 1999-02-16 The Gene Pool, Inc. Sequence-specific detection of nucleic acid hybrids using a DNA-binding molecule or assembly capable of discriminating perfect hybrids from non-perfect hybrids
US20030104361A1 (en) 1997-09-29 2003-06-05 Susan Weininger Method of detection of nucleic acids with a specific sequence composition
FR2733762B1 (fr) * 1995-05-02 1997-08-01 Genset Sa Methode de couplage specifique de la coiffe de l'extremite 5' d'un fragment d'arnm et preparation d'arnm et d'adnc complet
FR2733765B1 (fr) * 1995-05-02 1997-07-25 Genset Sa Methode de couplage specifique de la coiffe de l'extremite 5' d'un fragment d'arnm
FR2746413B1 (fr) * 1996-03-19 1998-04-24 Bio Merieux Detection d'une sequence nucleotidique avec amplification de signal
US5853993A (en) * 1996-10-21 1998-12-29 Hewlett-Packard Company Signal enhancement method and kit
AU5882000A (en) * 1999-06-22 2001-01-09 Invitrogen Corporation Improved primers and methods for the detection and discrimination of nucleic acids
US7838655B2 (en) * 2000-09-15 2010-11-23 Ventana Medical Systems, Inc. Oligonucleotide sequence formula for labeling oligonucleotide probes and proteins for in-situ analysis
WO2002102820A1 (en) 2001-06-20 2002-12-27 Nuevolution A/S Nucleoside derivatives for library preparation
WO2003024954A1 (en) * 2001-09-12 2003-03-27 Pusan National University Industry-University Cooperation Foundation Novel terthiophene-3-carboxylic acid compound and fabricating method thereof, functionalized conductive terthiophene polymer with the compound as a monomer, process for dna hybridizatioon detection using the polymer, and fabricating method of probe dna
DE10228260A1 (de) * 2002-06-25 2004-01-22 Bayer Ag Methode und Vorrichtung zum impedimetrischen Nachweis eines oder mehrerer Analyten in einer Probe
EP1539980B1 (en) 2002-08-01 2016-02-17 Nuevolution A/S Library of complexes comprising small non-peptide molecules and double-stranded oligonucleotides identifying the molecules
ES2368215T3 (es) * 2002-10-30 2011-11-15 Nuevolution A/S Codificación enzimática.
EP2175019A3 (en) * 2002-12-19 2011-04-06 Nuevolution A/S Quasirandom structure and function guided synthesis methods
US20070026397A1 (en) 2003-02-21 2007-02-01 Nuevolution A/S Method for producing second-generation library
DE602004023960D1 (de) 2003-09-18 2009-12-17 Nuevolution As Methode zur Gewinnung struktureller Informationen kodierter Moleküle und zur Selektion von Verbindungen
DE602006018648D1 (de) 2005-12-01 2011-01-13 Nuevolution As Enzymvermittelnde kodierungsmethoden für eine effiziente synthese von grossen bibliotheken
DE102006028101B4 (de) * 2006-06-19 2014-02-13 Siemens Aktiengesellschaft Verfahren zur Analyse von amplifizierten Nukleinsäuren
US8150101B2 (en) 2006-11-13 2012-04-03 Cybernet Systems Corporation Orientation invariant object identification using model-based image processing

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EP0119448A1 (en) * 1983-02-14 1984-09-26 Wakunaga Seiyaku Kabushiki Kaisha Oligonucleotide derivatives and production thereof
EP0124221A1 (en) * 1983-03-09 1984-11-07 Alan David Blair Malcolm Method of detecting a polynucleotide sequence and labelled polynucleotides useful therein
EP0185547A2 (en) * 1984-12-19 1986-06-25 E.I. Du Pont De Nemours And Company Polynucleotide hybridization assays employing catalyzed luminescence
EP0194545A2 (en) * 1985-03-15 1986-09-17 Molecular Diagnostics, Inc. Labelling of oligonucleotides
EP0232967A2 (en) * 1986-01-10 1987-08-19 Amoco Corporation Competitive homogeneous Assay
WO1987006270A1 (en) * 1986-04-16 1987-10-22 The Salk Institute For Biological Studies Replicative rna reporter systems
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WO1983002277A1 (en) * 1981-12-29 1983-07-07 Kourilsky, Philippe Dna fragments marked at least at one of the ends thereof by modified ribonucleotides recognizable by related molecules and method for analyzing such dna fragments
EP0119448A1 (en) * 1983-02-14 1984-09-26 Wakunaga Seiyaku Kabushiki Kaisha Oligonucleotide derivatives and production thereof
EP0124221A1 (en) * 1983-03-09 1984-11-07 Alan David Blair Malcolm Method of detecting a polynucleotide sequence and labelled polynucleotides useful therein
EP0185547A2 (en) * 1984-12-19 1986-06-25 E.I. Du Pont De Nemours And Company Polynucleotide hybridization assays employing catalyzed luminescence
EP0194545A2 (en) * 1985-03-15 1986-09-17 Molecular Diagnostics, Inc. Labelling of oligonucleotides
EP0232967A2 (en) * 1986-01-10 1987-08-19 Amoco Corporation Competitive homogeneous Assay
WO1987006270A1 (en) * 1986-04-16 1987-10-22 The Salk Institute For Biological Studies Replicative rna reporter systems
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Title
CLAIMS SEARCHED: ALL *

Also Published As

Publication number Publication date
EP0373956B1 (en) 1995-07-26
ATE125545T1 (de) 1995-08-15
US5324829A (en) 1994-06-28
EP0373956A2 (en) 1990-06-20
DE68923603T2 (de) 1996-01-04
ES2076219T3 (es) 1995-11-01
EP0373956A3 (en) 1991-01-30
JPH02245663A (ja) 1990-10-01
CA2005557A1 (en) 1990-06-16
US5521298A (en) 1996-05-28
DE68923603D1 (de) 1995-08-31
US5783685A (en) 1998-07-21

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