GR890100448A - Αλατα υδραλογονου της ριφαπεντινης. - Google Patents

Αλατα υδραλογονου της ριφαπεντινης.

Info

Publication number
GR890100448A
GR890100448A GR890100448A GR890100448A GR890100448A GR 890100448 A GR890100448 A GR 890100448A GR 890100448 A GR890100448 A GR 890100448A GR 890100448 A GR890100448 A GR 890100448A GR 890100448 A GR890100448 A GR 890100448A
Authority
GR
Greece
Prior art keywords
pct
rifapentine
sec
date
hydrohalides
Prior art date
Application number
GR890100448A
Other languages
English (en)
Other versions
GR1002222B (en
Inventor
Bruno Cavalleri
Marino Nebuloni
Emilio Occelli
Original Assignee
Lepetit Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lepetit Spa filed Critical Lepetit Spa
Publication of GR890100448A publication Critical patent/GR890100448A/el
Publication of GR1002222B publication Critical patent/GR1002222B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Fats And Perfumes (AREA)
  • Dental Preparations (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Liquid Crystal Substances (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)

Abstract

Λαμβάνονται τα άλατα προσ?ήκης οξέων της ριφαπεντίνης με υδροχλωρικό και υδροβρωμικό οξύ από τα υδατικά διαλύματα των ελευ?έρων βάσεων και οξέων υδραλογόνων. Η κρυστάλλωση από διαφορετικούς οργανικούς διαλύτες ή η καταβύ?ιση από διαλύτες δια προσ?ήκης μη διαλυτών αποδίδουν δύο διάκριτα πολυμορφικά σώματα και την άμορφη κατάσταση. Οι πολυμορφικές μορφές εμφανίζουν απο?ήκευση φαρμάκου με μεγάλη στα?ερότητα και υπό τις συνή?ως χρησιμοποιούμενες συν?ήκες για την μορφοποίηση των φαρμακευτικών δοσολογικών μορφών. ω
GR890100448A 1988-07-13 1989-07-13 Rifapentine hydrohalides GR1002222B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888816620A GB8816620D0 (en) 1988-07-13 1988-07-13 Rifapentine hydrohalides

Publications (2)

Publication Number Publication Date
GR890100448A true GR890100448A (el) 1990-06-27
GR1002222B GR1002222B (en) 1996-04-17

Family

ID=10640347

Family Applications (1)

Application Number Title Priority Date Filing Date
GR890100448A GR1002222B (en) 1988-07-13 1989-07-13 Rifapentine hydrohalides

Country Status (20)

Country Link
US (1) US5306715A (el)
EP (1) EP0440642B1 (el)
JP (1) JP2716553B2 (el)
KR (1) KR0135312B1 (el)
CN (1) CN1039421A (el)
AT (1) ATE111101T1 (el)
AU (1) AU632754B2 (el)
CA (1) CA1339215C (el)
DE (1) DE68918107T2 (el)
DK (1) DK173423B1 (el)
ES (1) ES2018374A6 (el)
GB (1) GB8816620D0 (el)
GR (1) GR1002222B (el)
HK (1) HK1005455A1 (el)
HU (1) HU210716A9 (el)
IE (1) IE65812B1 (el)
IL (1) IL90892A0 (el)
PT (1) PT91132B (el)
WO (1) WO1990000553A1 (el)
ZA (1) ZA894991B (el)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69111607T2 (de) * 1990-06-29 1995-12-21 Lepetit Spa Reine kristalline form von rifapentin.
HRP20000162B1 (en) 2000-03-20 2004-06-30 Pliva D D Amorphous torasemide modification
JP4393098B2 (ja) * 2002-06-21 2010-01-06 独立行政法人科学技術振興機構 アンサマイシン系抗生物質の新規用途及び新規血管新生抑制物質のスクリーニング方法
WO2004072040A1 (en) * 2003-02-12 2004-08-26 Ciba Specialty Chemicals Holding Inc. Crystalline forms of pitavastatin calcium
ITMI20032144A1 (it) * 2003-11-07 2005-05-08 Alfa Wassermann Spa Forme polimorfe di rifaximina, processi per ottenerle e
PT1698630E (pt) * 2005-03-03 2014-09-15 Alfa Wassermann Spa Novas formas polimorfas de rifaximina, processos para a sua produção e a sua utilização nas preparações medicinais
JP2007246514A (ja) * 2006-02-14 2007-09-27 Toyama Chem Co Ltd ピペラシリンナトリウムの新規な結晶
US20100063273A1 (en) * 2007-01-31 2010-03-11 Toyama Chemical Co., Ltd Novel crystal of piperacillin sodium
IT1398550B1 (it) 2010-03-05 2013-03-01 Alfa Wassermann Spa Formulazioni comprendenti rifaximina utili per ottenere un effetto prolungato nel tempo
CA2861104A1 (en) * 2012-01-25 2013-08-01 Salix Pharmaceuticals, Ltd. Rifaximin derivative and uses thereof
ITBO20120368A1 (it) 2012-07-06 2014-01-07 Alfa Wassermann Spa Composizioni comprendenti rifaximina e amminoacidi, cristalli di rifaximina derivanti da tali composizioni e loro uso.
US20240199642A1 (en) * 2021-04-21 2024-06-20 Interquim S.A. De C.V. Method for obtaining rifapentine with a new crystalline form

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR5518M (el) * 1964-07-31 1967-11-06
FR2309556A1 (fr) * 1975-04-29 1976-11-26 Aries Robert Aminoguanidines derivees de la rifamycine
US4002752A (en) * 1975-03-05 1977-01-11 Gruppo Lepetit S.P.A. Piperazinylimino rifamycins

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4876258A (en) * 1987-08-13 1989-10-24 Ciba-Geigy Corporation Biphenylyl compounds
US4916126A (en) * 1987-09-25 1990-04-10 Ciba-Geigy Corporation Diacyl derivatives of 4-(trialkylbenzyl)-piperazinyl compounds

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR5518M (el) * 1964-07-31 1967-11-06
US4002752A (en) * 1975-03-05 1977-01-11 Gruppo Lepetit S.P.A. Piperazinylimino rifamycins
FR2309556A1 (fr) * 1975-04-29 1976-11-26 Aries Robert Aminoguanidines derivees de la rifamycine

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CLAIMS SEARCHED: ALL *

Also Published As

Publication number Publication date
CA1339215C (en) 1997-08-05
IL90892A0 (en) 1990-02-09
KR900701798A (ko) 1990-12-04
EP0440642B1 (en) 1994-09-07
DK292590D0 (da) 1990-12-10
DE68918107T2 (de) 1995-01-26
EP0440642A1 (en) 1991-08-14
JP2716553B2 (ja) 1998-02-18
AU632754B2 (en) 1993-01-14
JPH03506025A (ja) 1991-12-26
KR0135312B1 (ko) 1998-04-23
GB8816620D0 (en) 1988-08-17
IE892247L (en) 1990-01-13
CN1039421A (zh) 1990-02-07
ATE111101T1 (de) 1994-09-15
DK292590A (da) 1990-12-10
HU210716A9 (en) 1995-06-28
AU3770289A (en) 1990-02-05
DE68918107D1 (de) 1994-10-13
HK1005455A1 (en) 1999-01-08
ES2018374A6 (es) 1991-04-01
PT91132A (pt) 1990-02-08
ZA894991B (en) 1990-08-29
IE65812B1 (en) 1995-11-15
WO1990000553A1 (en) 1990-01-25
US5306715A (en) 1994-04-26
GR1002222B (en) 1996-04-17
DK173423B1 (da) 2000-10-09
PT91132B (pt) 1994-12-30

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