GR851499B - - Google Patents

Info

Publication number
GR851499B
GR851499B GR851499A GR850101499A GR851499B GR 851499 B GR851499 B GR 851499B GR 851499 A GR851499 A GR 851499A GR 850101499 A GR850101499 A GR 850101499A GR 851499 B GR851499 B GR 851499B
Authority
GR
Greece
Application number
GR851499A
Other languages
Greek (el)
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of GR851499B publication Critical patent/GR851499B/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003Androstane derivatives
    • C07J1/0011Androstane derivatives substituted in position 17 by a keto group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J13/00Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/005Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005Ketals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J53/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002Carbocyclic rings fused
    • C07J53/0043 membered carbocyclic rings
    • C07J53/0083 membered carbocyclic rings in position 15/16
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/001Oxiranes
    • C07J71/0015Oxiranes at position 9(11)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GR851499A 1984-06-21 1985-06-19 GR851499B (US06633600-20031014-M00021.png)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH300984 1984-06-21
CH464684 1984-09-28

Publications (1)

Publication Number Publication Date
GR851499B true GR851499B (US06633600-20031014-M00021.png) 1985-11-25

Family

ID=25691934

Family Applications (1)

Application Number Title Priority Date Filing Date
GR851499A GR851499B (US06633600-20031014-M00021.png) 1984-06-21 1985-06-19

Country Status (16)

Country Link
US (1) US4670551A (US06633600-20031014-M00021.png)
EP (1) EP0165902B1 (US06633600-20031014-M00021.png)
AR (2) AR242036A1 (US06633600-20031014-M00021.png)
AU (1) AU582754B2 (US06633600-20031014-M00021.png)
CA (1) CA1239388A (US06633600-20031014-M00021.png)
DE (1) DE3569540D1 (US06633600-20031014-M00021.png)
DK (1) DK173854B1 (US06633600-20031014-M00021.png)
ES (2) ES8704967A1 (US06633600-20031014-M00021.png)
FI (1) FI83225C (US06633600-20031014-M00021.png)
GR (1) GR851499B (US06633600-20031014-M00021.png)
HU (1) HU192232B (US06633600-20031014-M00021.png)
IE (1) IE58050B1 (US06633600-20031014-M00021.png)
IL (1) IL75569A (US06633600-20031014-M00021.png)
NO (1) NO165496C (US06633600-20031014-M00021.png)
NZ (1) NZ212492A (US06633600-20031014-M00021.png)
PT (1) PT80663B (US06633600-20031014-M00021.png)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE365171T1 (de) * 1995-12-11 2007-07-15 Searle Llc Verfahren zur herstellung einer epoxyverbindung
US6887991B1 (en) 1996-12-11 2005-05-03 G. D. Searle & Company Processes for preparation of 9, 11-epoxy steroids and intermediates useful therein
NZ336004A (en) 1996-12-11 2001-04-27 G Process for preparation of 3-keto-7-alpha-alkoxycarbonyl substituted delta-4,5-steroid by reacting 4,5-dihydro-5,7-lactone steroid substrate in the presence of a base
EP1223174A3 (en) * 1996-12-11 2005-03-16 G.D. Searle & Co. Processes for preparation of 3-keto-7alpha-alkoxycarbonyl-delta-4,5- steroids and intermediates useful therein
AU4093799A (en) 1998-05-22 1999-12-13 Board Of Trustees Of The Leland Stanford Junior University Bifunctional molecules and therapies based thereon
KR20040080439A (ko) 2001-12-12 2004-09-18 파마시아 코포레이션 에폭시-스테로이드성 알도스테론 수용체 길항제에 의한안구 질환의 치료 방법
US7235655B2 (en) 2002-03-22 2007-06-26 Pharmacia & Upjohn Company Processes to prepare eplerenone
PT1889198E (pt) 2005-04-28 2015-03-06 Proteus Digital Health Inc Sistema fármaco-informático
WO2007025780A2 (en) * 2005-09-02 2007-03-08 Recordati Ireland Limited Aldosterone receptor antagonists
JP2009508494A (ja) 2005-09-16 2009-03-05 ラプトール ファーマシューティカル インコーポレイテッド Crを含むタンパク質に対して特異的な受容体−結合タンパク質(rap)変異体を含む組成物およびその使用
PT2398500T (pt) 2009-02-20 2019-06-14 2 Bbb Medicines B V Sistema de entrega de medicamentos à base de glutationas
ES2942923T3 (es) 2009-05-06 2023-06-07 Laboratory Skin Care Inc Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3013012A (en) * 1960-12-22 1961-12-12 Searle & Co Alkanoylthio-17alpha-carboxyethyl-17beta-hydroxyandrosten-3-one lactones
US3095412A (en) * 1961-12-19 1963-06-25 Searle & Co 9alpha, 11alpha-epoxy and 11beta-chloro-9alpha-hydroxy 17alpha-(2-carboxyethyl)-17beta-hydroxyandrost-4-en-3-one gamma-lactones and delta1 and delta6 analogs
GB1041534A (en) * 1963-04-24 1966-09-07 Merck & Co Inc 20-spiroxane compounds
DE2652761C2 (de) * 1976-11-16 1985-11-21 Schering AG, 1000 Berlin und 4709 Bergkamen 15,16-Methylen-Spirolactone, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
US4559332A (en) * 1983-04-13 1985-12-17 Ciba Geigy Corporation 20-Spiroxanes and analogues having an open ring E, processes for their manufacture, and pharmaceutical preparations thereof
EP0134529B1 (de) * 1983-08-17 1990-03-21 Schering Aktiengesellschaft 7-alpha-Substituierte 3-Oxo-17alpha-pregn-4-en-21.17-carbolactone, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate

Also Published As

Publication number Publication date
AR242036A1 (es) 1993-02-26
FI852430A0 (fi) 1985-06-19
ES8707737A1 (es) 1987-08-16
DK280085A (da) 1985-12-22
DK173854B1 (da) 2001-12-27
FI852430L (fi) 1985-12-22
NO165496B (no) 1990-11-12
NO165496C (no) 1991-02-20
NO852501L (no) 1985-12-23
AR245731A1 (es) 1994-02-28
PT80663B (en) 1987-05-08
CA1239388A (en) 1988-07-19
FI83225B (fi) 1991-02-28
HU192232B (en) 1987-05-28
NZ212492A (en) 1989-02-24
IE58050B1 (en) 1993-06-16
IE851535L (en) 1985-12-21
IL75569A0 (en) 1985-10-31
DE3569540D1 (en) 1989-05-24
EP0165902A2 (de) 1985-12-27
ES544387A0 (es) 1987-04-16
AU582754B2 (en) 1989-04-13
DK280085D0 (da) 1985-06-20
IL75569A (en) 1989-03-31
PT80663A (en) 1985-07-01
AU4397185A (en) 1986-01-02
US4670551A (en) 1987-06-02
EP0165902A3 (en) 1986-10-22
FI83225C (fi) 1991-06-10
HUT38367A (en) 1986-05-28
ES557112A0 (es) 1987-08-16
ES8704967A1 (es) 1987-04-16
EP0165902B1 (de) 1989-04-19

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