GR79445B - - Google Patents

Info

Publication number
GR79445B
GR79445B GR73353A GR830173353A GR79445B GR 79445 B GR79445 B GR 79445B GR 73353 A GR73353 A GR 73353A GR 830173353 A GR830173353 A GR 830173353A GR 79445 B GR79445 B GR 79445B
Authority
GR
Greece
Prior art keywords
compositions
piperazinyl
cyclopropyl
dihydro
oxo
Prior art date
Application number
GR73353A
Other languages
English (en)
Inventor
Uwe Dr Petersen
Klaus Dr Grohe
Hans Joachim Dr Zeiler
Karl Georg Dr Metzger
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6182078&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GR79445(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of GR79445B publication Critical patent/GR79445B/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
GR73353A 1982-12-29 1983-12-27 GR79445B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19823248506 DE3248506A1 (de) 1982-12-29 1982-12-29 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7(alkyl-1-piperazinyl)-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel

Publications (1)

Publication Number Publication Date
GR79445B true GR79445B (el) 1984-10-30

Family

ID=6182078

Family Applications (1)

Application Number Title Priority Date Filing Date
GR73353A GR79445B (el) 1982-12-29 1983-12-27

Country Status (20)

Country Link
US (1) US4544658A (el)
EP (1) EP0113093B1 (el)
JP (1) JPS59130880A (el)
KR (2) KR870000901B1 (el)
AT (1) ATE19877T1 (el)
AU (1) AU560153B2 (el)
CA (1) CA1218070A (el)
DD (1) DD216016A5 (el)
DE (2) DE3248506A1 (el)
DK (1) DK160989C (el)
ES (1) ES8406846A1 (el)
FI (1) FI79102C (el)
GR (1) GR79445B (el)
HU (1) HU191392B (el)
IE (1) IE56460B1 (el)
IL (1) IL70539A (el)
NO (1) NO162236C (el)
NZ (1) NZ206705A (el)
PH (3) PH20545A (el)
ZA (1) ZA839646B (el)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3420798A1 (de) * 1984-06-04 1985-12-05 Bayer Ag, 5090 Leverkusen 7-(3-aryl-l-piperazinyl)- sowie 7-(3-cyclohexyl-l-piperazinyl)-3-chinoloncarbonsaeuren
DE3420743A1 (de) * 1984-06-04 1985-12-05 Bayer Ag, 5090 Leverkusen 7-amino-1-cyclopropyl-6,8-dihalogen-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
DE3420770A1 (de) * 1984-06-04 1985-12-05 Bayer Ag, 5090 Leverkusen 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7-(3-oxo-1-piperazinyl)-3-chinoloncarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
US5468861A (en) * 1984-06-04 1995-11-21 Bayer Aktiengesellschaft 8-chloro-1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid and alkyl esters thereof
DE3426483A1 (de) * 1984-07-18 1986-01-30 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von halogenierten chinoloncarbonsaeuren
DE3435392A1 (de) * 1984-09-27 1986-04-03 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von 2,4-dichlor-5-fluor-benzoesaeure
JPS6191183A (ja) * 1984-10-11 1986-05-09 Kyorin Pharmaceut Co Ltd キノロンカルボン酸誘導体
US4636506A (en) * 1984-12-06 1987-01-13 Pfizer, Inc. 7-heterocyclic-1,4-dihydroquinolones
DE3576335D1 (de) * 1984-12-14 1990-04-12 Daiichi Seiyaku Co Chinolincarbonsaeure-derivate.
DE3508816A1 (de) * 1985-01-10 1986-07-10 Bayer Ag, 5090 Leverkusen 6,7-disubstituierte 1-cyclopropyl-1,4-dihydro-4-oxo-1,8-naphtyridin-3-carbonsaeuren
DE3509546A1 (de) * 1985-03-16 1986-09-25 Bayer Ag, 5090 Leverkusen 7-amino-1-(subst.cyclopropyl)-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
AU594983B2 (en) 1985-10-29 1990-03-22 Dainippon Pharmaceutical Co. Ltd. Novel quinoline derivatives and processes for preparation thereof
DE3617803A1 (de) * 1985-11-07 1987-11-19 Bayer Ag Verwendung von gyrasehemmern zur dekontamination von mycoplasma-infizierten zellkulturen
DE3542002A1 (de) * 1985-11-28 1987-06-04 Bayer Ag 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7- (1-piperazinyl)-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
US4977154A (en) * 1985-12-12 1990-12-11 Warner-Lambert Company 5-amino and 5-hydroxy-6-fluoroquinolones as antibacterial agents
US4940710A (en) * 1986-01-17 1990-07-10 American Cyanamid Company 7-(substituted)piperazinyl-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids
US5210193A (en) * 1986-01-17 1993-05-11 American Cyanamid Company Piperazine derivatives
DE3705621C2 (de) * 1986-02-25 1997-01-09 Otsuka Pharma Co Ltd Heterocyclisch substituierte Chinoloncarbonsäurederivate
JPS62215572A (ja) * 1986-03-17 1987-09-22 Kyorin Pharmaceut Co Ltd キノロンカルボン酸誘導体
IL88003A (en) * 1987-10-16 1992-11-15 Dainippon Pharmaceutical Co Quinoline derivatives,their preparation and pharmaceutical compositions containing them
US5164392A (en) * 1987-10-16 1992-11-17 Dainippon Pharmaceutical Co., Ltd. Quinoline derivatives and antibacterial agent containing them
AU683569B2 (en) * 1994-07-18 1997-11-13 Sankyo Company Limited Trifluoromethylquinolinecarboxylic acid derivative
JP3449658B2 (ja) * 1994-12-21 2003-09-22 杏林製薬株式会社 安定性に優れた8−アルコキシキノロンカルボン酸水和物並びにその製造方法
US6387928B1 (en) 1997-09-15 2002-05-14 The Procter & Gamble Co. Antimicrobial quinolones, their compositions and uses
CA2303389C (en) 1997-09-15 2007-07-17 The Procter & Gamble Company Antimicrobial quinolones, their compositions and uses
KR100821894B1 (ko) * 2004-07-02 2008-04-16 주식회사 코오롱 항균 염료 및 그를 이용한 항균 섬유
DK2001862T3 (da) * 2006-03-28 2011-08-08 Warner Chilcott Co Llc Malatsalte og polymorfe af (3S,5S)-7-[3-amino-5-methyl-piperidinyl]-1-cyklopropyl-1,4-dihydro-8-methoxy-4-oxo-3-quinolincarboxylsyre
CA2647457C (en) * 2006-03-28 2011-05-24 The Procter & Gamble Company A hydride reduction process for preparing quinolone intermediates
CA2647454A1 (en) * 2006-03-28 2007-10-04 The Procter & Gamble Company A coupling process for preparing quinolone intermediates

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3149104A (en) * 1961-01-03 1964-09-15 Sterling Drug Inc 4-hydroxy-7-styryl-1, 8-naphthyridine-3-carboxylic acids and esters
DE2808070A1 (de) * 1978-02-24 1979-08-30 Bayer Ag Verfahren zur herstellung von 4-pyridon-3-carbonsaeuren und/oder deren derivaten
DE3142854A1 (de) * 1981-10-29 1983-05-11 Bayer Ag, 5090 Leverkusen 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7-piperazino-chinolin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
DE3033157A1 (de) * 1980-09-03 1982-04-01 Bayer Ag, 5090 Leverkusen 7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-naphthyridin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel

Also Published As

Publication number Publication date
HU191392B (en) 1987-02-27
NO834632L (no) 1984-07-02
DK160989B (da) 1991-05-13
FI834806A0 (fi) 1983-12-27
PH22453A (en) 1988-09-12
IE833034L (en) 1984-06-29
FI79102B (fi) 1989-07-31
ES528495A0 (es) 1984-09-01
KR870001003B1 (ko) 1987-05-18
DK160989C (da) 1991-10-28
CA1218070A (en) 1987-02-17
NZ206705A (en) 1986-01-24
ZA839646B (en) 1984-08-29
IL70539A (en) 1987-08-31
KR870000901B1 (ko) 1987-05-04
DE3248506A1 (de) 1984-07-05
NO162236C (no) 1989-11-29
JPH0323549B2 (el) 1991-03-29
AU2251083A (en) 1984-07-05
ES8406846A1 (es) 1984-09-01
PH20545A (en) 1987-02-09
AU560153B2 (en) 1987-04-02
US4544658A (en) 1985-10-01
DK604083D0 (da) 1983-12-28
FI834806A (fi) 1984-06-30
NO162236B (no) 1989-08-21
DK604083A (da) 1984-06-30
DE3363608D1 (en) 1986-06-26
JPS59130880A (ja) 1984-07-27
PH21478A (en) 1987-10-28
IL70539A0 (en) 1984-03-30
ATE19877T1 (de) 1986-06-15
FI79102C (fi) 1989-11-10
EP0113093A1 (de) 1984-07-11
KR840006990A (ko) 1984-12-04
IE56460B1 (en) 1991-08-14
EP0113093B1 (de) 1986-05-21
DD216016A5 (de) 1984-11-28

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IL66192A0 (en) Antibiotic compounds,their production and pharmaceutical compositions containing them